埃隆·马斯克:Neuralink 与人类的未来
Elon Musk: Neuralink and the Future of Humanity
马斯克与 Neuralink 团队谈脑机接口的技术进展,以及它如何改变人与机器的关系。
一个肩膀以下没有知觉的人,靠想的,把《文明6》连续玩了八九个小时。这个时长超过了他出事之前自己的最好成绩。
他叫 Noland Arbaugh。2019 年一次潜水事故,颈椎第五、六节受损,肩膀以下失去知觉。2024 年 1 月 29 日,他成为 Neuralink 第一位人类受试者。手术几小时后,他用意念把光标移到了屏幕上的目标位置。第二天回家,他玩了一整晚游戏,玩到电池没电。
Lex Fridman 这期访谈就在 Neuralink 的园区里录。Elon Musk 带他看了那台叫 R1 的手术机器人,看了插进脑子里的那根线到底有多细,也讲了那个让整个团队几周没睡好的意外:术后一段时间,大部分电极从脑组织里退了出来。
一根比红细胞粗不了多少的线
先说硬件。Neuralink 的植入体叫 Link,硬币大小,直径 23 毫米,厚 8 毫米,嵌在头骨上打出的孔里,头皮盖回去以后外面看不出来。真正进入大脑的部分是 64 根线,每根线上 16 个电极,加起来 1024 个通道。
这些线的直径大约 10 微米。红细胞直径七八微米,一根线比红细胞粗不了多少。线太硬会划伤组织,太软又插不进去,材料学和力学在这里互相拉扯了很多年。
人能手工把这 64 根线插进大脑吗?插一根也许可以,插一千个通道就是另一回事。血管分布在皮层表面,扎破一根就是一次微出血。所以有了 R1。
R1 的工作方式是这样的:先用光学相干断层扫描(OCT)给脑表面的血管拍一张三维地图,然后为每一根针规划一条单独的进入路径,绕开所有血管,把针送进去几毫米,退出来,换下一根。整个过程需要微米级定位,靠人手不可能稳定做到。
Musk 在这里讲了一句很实在的话,大意是人脑有 860 亿个神经元,我们现在接上的 1024 个通道连一根汗毛都算不上,但这已经足够让一个瘫痪的人重新操作电脑。他没有把 1024 说成什么了不起的数字,反而先说它有多小,再说它够用。这个说法比任何性能吹嘘都更有说服力。
电极退出来的那个月,软件救了硬件
手术之后几周,数据开始变差。团队发现 Noland 脑子里大部分电极线缩回了皮层,有效通道数掉到只剩一小部分。当时的公开说法是,大约 85% 的线出现了回缩,能读到信号的比例大幅下降。
这是脑机接口领域最经典的失败模式。脑组织是软的,会随着呼吸和心跳轻微移动,异物长期留在里面,周围会形成胶质疤痕,电极要么被包裹,要么被推开。过去几十年,无数实验室死在这一步。
Neuralink 的处理方式值得单独拎出来讲。他们没有立刻做第二次手术,而是改了软件。原来的解码算法把所有通道的信号做平均,通道一少,信噪比就崩了。工程师改成对每个剩余通道单独建模、动态校准,再重新训练解码模型。
结果性能不但恢复了,还超过了刚植入时的水平。后来公开的测试里,Noland 的控制速率达到每秒 4.6 比特,比之前非人灵长类身上的最好记录还高一点。
硬件出了问题,我们用软件把它救回来了。这就是为什么从头到尾所有东西都得自己做。(埃隆·马斯克)
这句话背后的逻辑比听起来更重要。一家只做电极的公司,遇到回缩只能回去改材料;一家只做算法的公司,根本拿不到原始信号。垂直整合在这里换来的是反应速度。
Noland 后来做的事包括:和朋友下国际象棋并且赢了、玩《马里奥赛车》撞墙、用语音合成读书、连续八九个小时打《文明6》。这些事对普通人毫无难度,对一个肩膀以下没知觉的人,是重新拿回了对世界的操作权。
目标是十分钟做完,像配眼镜一样
现在的植入手术大约两小时。Musk 说的目标是把它压到十分钟,让整个过程接近做一次 LASIK 激光近视手术:走进诊所,坐下来,做完,回家。
头骨上打孔用的是激光,传统钻头被换掉了。他特意强调这个细节,因为激光打孔不出血,切口边缘平滑,术后不需要缝针,用医用胶水封住就行。整个流程里最耗时的部分其实不在插线,在准备和定位。
成本是另一条线。他给出的目标是几千美元,和一台 LASIK 手术同一个量级。这个数字决定了产品的性质:一台手术要一百万,它就是个实验室玩具,全世界只有几百个富人能用;几千美元,医保有可能覆盖,它才成为医疗器械。
要让这件事成立,手术必须自动化。全世界能做这种精细神经外科手术的医生只有几千人,靠人手一台一台做,永远到不了每年几万台的量级。R1 承担的角色是产能前提,跟炫技没关系。
患者数量的时间表,Musk 给得挺激进:五年内做到数万人,十年内做到数百万人。他没说这一定会发生,只说按他的判断这是可能的路径。2024 年实际完成的是三例,第一例 Noland,第二例 Alex,第三例 Brad。Alex 术前要靠嘴叼着触控笔在屏幕上画图,植入后能直接操作 CAD 软件做三维设计。Brad 患有 ALS,用设备控制鼠标和机械臂。
Blindsight:不去修眼睛,直接找视皮层
访谈里 Lex 问了一个很自然的问题:下一个产品是什么。Musk 的回答是视觉,产品名叫 Blindsight。
逻辑很干净。人看见东西的路径是:光进入眼睛,视网膜转成电信号,视神经传到视觉皮层,皮层处理。这条链上任何一环坏了都会失明。视觉皮层本身还好,前面所有环节都可以绕过:摄像头采集图像,芯片编码成电刺激模式,直接打进视皮层。
这个思路在动物实验里已经有基础。Neuralink 在猴子身上做过类似的东西,用刺激让猴子“看到”实际上不存在的形状。Musk 说初期分辨率很低,看起来像早期雅达利游戏那种粗糙的点阵,但通道数往上堆,清晰度就会跟着涨。
他甚至讲了一个更远的可能性:人眼只能感受到可见光这一小段电磁波,用脑机接口,理论上可以让人“看到”红外线、紫外线,甚至雷达回波。这在物理上说得通,视觉皮层处理的是电信号,它不关心信号从哪来。摄像头换成红外传感器,人就能在黑暗里看见热源。
一开始的分辨率会像早期的任天堂游戏,但每一代都会更好。最终我们可能看到比自然视力更多的东西。(埃隆·马斯克)
Blindsight 已经拿到美国 FDA 的突破性设备认定。这个认定的含义是监管机构认为它有潜力治疗严重疾病,愿意加快审评流程,离批准上市还差得远。
带宽才是人机融合的真正理由
前面讲的都是医疗。访谈里真正重要的那一段,讲的是别的东西。
Musk 有一个反复出现的观察:人的输入带宽远大于输出带宽。你能看见、听见、感受到的信息量是巨大的,但你输出信息的通道只有两根手指和一张嘴。打字每分钟几十个词,说话每分钟一百五十个词,剩下的想法全部堵在里面出不来。
他喜欢拿时间来算这笔账:一天 86400 秒,接收的信息铺天盖地,输出出去的那点东西速率低到可以忽略。人类的智能要和远超自己的 AI 共存,输入输出之间的这道窄门就成了瓶颈。
他的解法是把带宽提上去。往皮层里多插几千个通道,让人和机器之间的对话速率从每秒几十比特涨到每秒几兆比特。这个目标他说得非常具体:把人的输出带宽提升一千倍甚至一万倍。这个数量级一旦达成,人和 AI 的关系就不再是“人类打字提问、AI 回答”,而是某种更接近融合的状态。你想到什么,机器立刻接住;机器的输出,你直接感知,不用经过眼睛和耳朵这两个慢速接口。
他在访谈里用了一个词叫概念层面的心灵感应(concept-level telepathy)。这个说法容易被当成科幻修辞,拆开看有实际含义:语言本身是低带宽的压缩编码,你脑子里一个完整的意思,压成一句话,对方再解压,中间丢了多少东西没人算得清。两个人在同一件事上磨合十年,往往是因为他们绕开了语言,通过共同经历建立了别的通道。脑机接口要做的是把这条通道直接铺出来,跳过压缩和解压这两道损耗。
他为什么急着做这件事
访谈里最能看出动机的一段,是 Musk 谈数字超级智能。
他的判断是:数字智能的规模迟早会远远超过生物智能。这跟哪家公司赢不赢没关系,是算力、内存、带宽这几条曲线叠加之后的结果。人类大脑的神经元数量固定在 860 亿左右,几十年没有变化;机器那边的数字每年都在翻。
他的结论是,人类面对这个局面只有两个选项:要么被甩在后面,要么想办法挤进同一辆车里。他把脑机接口定位成后者。
如果数字超级智能远远超过人类,那人类的意义在哪里?我们能做的最好的事,是提高人类与 AI 之间的带宽,让人类成为这个整体的一部分,而不是被落下。(埃隆·马斯克)
这段话里有一个隐含前提值得挑出来:他把“融合”当成默认的安全路径,“控制”被排在了后面。这几年 AI 安全领域的主流讨论集中在如何约束模型、如何对齐、如何立法,Musk 的路线是另一条,他觉得约束不住,所以选择混进去。
两种思路的差别在于对时间尺度的判断。你相信还有三十年窗口期,那监管和对齐研究是正解;你相信窗口只剩五年十年,那就得给自己装个接口。他不止一次在公开场合说,这是他做 Neuralink 的真实原因,跟医疗应用没太大关系。医疗是必要的第一步,因为只有病人才可能合法接受开颅手术。
从治病到增强,中间隔着一道很硬的墙
Lex 顺着问了一个关键问题:什么时候普通人会愿意为了增强而不是治疗去做这个手术。
Musk 的回答很务实:得等到它足够安全、足够便宜,而且你得先有一个能说服人的用途。他举的例子是渐冻症和严重脊髓损伤,这些人的收益是巨大的,风险可以接受。健康人没有这个计算基础,一次开颅手术的感染风险、免疫反应风险、长期稳定性风险,任何一项都可能让正常人退回去。
所以他排了一个顺序:先治病,让几千人用上,证明长期安全;再扩展到更轻的适应症,比如严重抑郁、癫痫、病理性肥胖;最后才是健康人的认知增强。这条路走完,他自己也说需要十年以上。
中间那道墙有技术的一半,也有伦理和监管的一半。FDA 批准一个医疗器械,看的是收益风险比,病人有明确的病理状态可以拿来对比,健康人没有。给一个健康人做开颅手术,哪怕并发症概率只有百分之一,伦理委员会也很难签字。
历史上所有增强技术的路径都是这样:先是给残障人士用的假肢、助听器、激光矫正视力,然后才慢慢被正常人接过去。LASIK 当年也是从治疗近视起步,最后变成了消费级项目。Musk 反复提 LASIK,就是因为这条路径他心里有数。
隐私:脑子里想的东西算不算证据
Lex 提了一个不太舒服的问题:如果脑子里有设备,别人能不能读你的想法。
Musk 的回答分两层。技术层面,现在的设备只能读到运动皮层的放电模式,也就是“我要把光标往左移”这类意图,读不出你在想什么具体的词。要读到语义层面,需要的通道数和算法精度还差得远。
他也承认,长期看这是个真问题。设备能读的东西越来越多,“思想隐私”这个概念的法律基础就变得模糊。法律上,证词受不自证其罪原则保护,但脑信号算不算证词?现在没有答案。
Neuralink 在这一点上做的设计是本地处理加加密传输,数据在芯片上处理完才出去,外部读不到原始信号。这个设计能挡住一部分攻击,挡不住设备厂商自己。权限最终落在谁手里,是产品之外的问题。
他在这里没有给出让人安心的答案。他说的是,这类问题得靠立法和社会共识慢慢解决,技术在跑,制度在后追,历史上所有强技术的路径都是这样。
动物实验那场风波
访谈里没有回避这个话题。2022 年前后,路透社等媒体报道 Neuralink 的动物实验存在过量死亡,涉及猴子、猪、羊,美国农业部监察长办公室介入调查。后来调查的结论是没发现违反《动物福利法》的行为,争议没有完全平息。
Musk 的回应有两点。第一点是实验设计上的辩解:外科手术本身的失败率在动物身上就是存在的,尤其是早期学习曲线阶段,团队后来通过改进 R1 的路径规划和术后护理把死亡率降下来了。第二点是他强调 Neuralink 现在建的实验设施标准比大学实验室高,还给猴子配了娱乐设施,因为动物的精神状态会影响数据质量。
这段话容易被读成公关修辞。有一点是技术性的:脑机接口的动物实验对数据质量要求极高,动物焦虑会导致信号噪声大、行为不可复现,改善动物福利和数据质量在这里是同一件事。这个动机和纯伦理动机并存,不冲突。
和 Optimus 的关系,以及为什么这家公司自己造一切
访谈中段 Lex 问了一个结构性问题:Neuralink 和 Tesla 的机器人业务有没有交集。
Musk 的回答是,电动机、精密控制、传感器、电源管理这几个模块,两边的技术栈有大量重叠。Neuralink 的植入体需要极低功耗的芯片和极小的封装,这些能力反过来可以给机器人用。他甚至提到,未来如果 Optimus 这类机器人要和人协作,脑机接口可能是一个自然的交互通道,人不用说话,机器人直接知道你想让它做什么。
他对垂直整合的解释,信息量更大。Neuralink 从芯片设计、电极材料、手术机器人、封装工艺到解码算法全部自己做。理由是,这个领域没有任何一个环节有现成供应商,你要的规格市面上买不到,等待供应商研发的时间比自己做的还长。
我们从零开始造所有的东西,因为没有任何现成的东西可用。(埃隆·马斯克)
这句话在别的行业听起来像控制欲,在脑机接口这个领域是现实。全世界每年卖出去的神经电极总量很少,没有哪家公司有动力为它开一条专用产线。你只能自己变成那家产线。
这个选择还有一个副作用,平时不太被提到:全链条自研意味着每一次失败都能拿到完整的上下游数据。电极回缩那次,团队能改的是算法,凭的是他们手里同时有硬件规格、手术路径记录和原始神经信号这三样东西。任何一环外包出去,这个反应速度都拿不到。
意识、死亡,和被问到的那几个问题
访谈后段,Lex 把话题拉到了哲学层面。他问 Musk,你怕不怕死。
Musk 的回答很平:怕,但想通了。他说他读过很多关于死亡和意义的讨论,最后落在一个相对朴素的立场上,如果宇宙的意义在于理解自身,那么个体意识的消失没那么可怕,可怕的是整个求知的过程被打断。这也是他不断强调“扩大意识的范围和尺度”的原因,他把这句话当成 SpaceX 和 Neuralink 共同的底层动机。
Lex 追问了一个更私人的问题:如果有一天你能把自己的意识上传,你会上传吗。
Musk 的回答有点绕。他说,上传的那个东西是你自己的副本,你不在里面。副本会觉得自己是你。这个区分他讲得很清楚,也说明他对“数字化永生”这类说法保持距离。Neuralink 的目标不在上传,在你活着的时候提高你和机器的带宽。
这一段里他对“意义”的表述值得记一下:他说人类存在的价值,可能在于我们是宇宙用来理解自己的那部分。这个说法不新,他把它当成了工程目标的指导原则,不只是一句心灵鸡汤。
他对时间表的诚实之处
整场访谈里,Musk 在时间表上的表述有一个明显的变化。谈手术机器人、谈电极数量、谈解码算法,他给的数字很具体,误差通常在几年之内。谈“数百万人用上脑机接口”这种远期目标,他会加一句“这是我的判断,不保证”。
这个差别本身就是信息。工程细节他已经想清楚了,社会层面的路径他也在赌。他心里清楚特斯拉的完全自动驾驶跳票了多少次,所以在这种场合他会主动留出余地。
Lex 没有追着问这个矛盾,只是把话题引回了具体的病人身上。访谈最后回到 Noland、Alex、Brad 这三个人,回到他们现在能做什么、不能做什么、下一步希望解决什么。这个收尾方式是有意的,把宏大叙事重新落回到具体的人身上。
Brad 说的一句话大意是,他失去的东西里,行动能力只是表面,真正被拿走的是选择权。今天想做什么、明天去哪里、怎么安排一天,全部依赖别人。设备给他的东西,实质是把这些选择权还回来一部分。
这件事的边界在哪里
把整场访谈看下来,Neuralink 现在做到的事情可以很清楚地说出来:让重度瘫痪的人用意念控制光标和机械臂,速度接近正常人用鼠标的水平;让 ALS 患者重新获得和外界沟通的通道;让第一个受试者连续玩八九个小时的游戏。
它还没做到的事情同样清楚:长期稳定性没有解决,电极回缩的问题只是被软件绕过去了,十年后这些线还在不在原位、信号还剩多少,没人知道。开颅手术的风险没有消失,只是被优化了。健康人用得上的场景,一个都还没有。
Musk 在访谈里最诚实的一句话,大概是他承认这个技术在早期会让很多人失望。他没有说“我们会成功”,他说的是“我们会尽量把失败率降下来”。
脑机接口这个领域过去五十年的历史,就是不断有人在电极稳定性上失败。Neuralink 的不同之处不在于它解决了这个问题,在于它有资源把失败一次又一次地重做,每次失败之后能拿到完整的工程数据。这个能力,学术界没有,小公司也没有。
至于那条通往“人机融合”的路线图,它成立的前提是三个数字同时往前推:通道数、手术安全性、成本。任何一个卡住,整条路径都停在原地。而这三个数字现在的起点,一个是 1024,一个是两小时,一个是几十万美元。
Noland 用这套系统下了棋、打了游戏、读了一本书。这些事加起来的分量,大概比所有关于超级智能的讨论都重。
- 如果你关心脑机接口的技术进展,不要只看发布会,去看 Neuralink 公布的患者使用视频和每月的进展更新,那里才有真实的带宽、通道数、使用时长数据。
- 判断这类公司时,把“垂直整合程度”当成一个硬指标看。能做电极、做芯片、做手术机器人、做解码算法全链条的公司,遇到失败时的反应速度是别家的几倍,Noland 那次电极回缩就是活例子。
- 在讨论 AI 风险时,把“融合路线”和“对齐路线”分开看。这两条路的假设完全不同,前者赌时间窗口不够,后者赌制度和研究能追上,混在一起讨论只会得出空泛结论。
- 如果你是医疗或康复领域的从业者,值得现在就开始关注重度瘫痪患者的实际使用案例,这类设备进入临床的路径,会先经过康复科而不是神经外科。
- 普通人现在不需要为“要不要装脑机接口”做决定,但可以留意一个信号:当某家公司的适应症从“严重瘫痪”扩展到“重度抑郁”或“病理性肥胖”时,说明安全性和审批路径都往前推了一大步,那才是消费级产品的前夜。
The following is a conversation with Elon Musk, DJ Seo, Matthew MacDougall, Bliss Chapman, and Noland Arbaugh about Neuralink and the future of humanity.
以下是与 Elon Musk、DJ Seo、Matthew MacDougall、Bliss Chapman 和 Noland Arbaugh 关于 Neuralink 和人类未来的对话。
00:00 Elon, DJ, Matthew and Bliss are of course part of the amazing Neuralink team, and Noland is the first human to have a Neuralink device implanted in his brain.
Elon、DJ、Matthew 和 Bliss 当然都是令人惊叹的 Neuralink 团队的成员,而 Noland 是第一个在大脑中植入 Neuralink 设备的人。
I speak with each of them individually, so use timestamps to jump around, or as I recommend, go hardcore, and listen to the whole thing.
我会单独与他们每个人交谈,因此请使用时间戳来跳转,或者按照我的建议,进行硬核,并聆听整个内容。
This is the longest podcast I’ve ever done.
这是我做过的最长的播客。
It’s a fascinating, super technical, and wide-ranging conversation, and I loved every minute of it.
这是一次引人入胜、技术含量高、范围广泛的对话,我喜欢其中的每一分钟。
And now, dear friends, here’s Elon Musk, his fifth time on this, the Lex Fridman podcast,
现在,亲爱的朋友们,这是埃隆·马斯克,他第五次参加莱克斯·弗里德曼播客,
Drinking coffee or water?
喝咖啡还是水?
Water.
水。
00:51 I’m so over-caffeinated right now.
我现在咖啡因过量了。
Do you want some caffeine?
你想要一些咖啡因吗?
Sure.
当然。
There’s a Nitro drink.
有一种硝基饮料。
This supposed to keep you up for like tomorrow afternoon, basically.
基本上,这应该能让你在明天下午保持清醒。
Yeah.
是的。
01:08 Yeah.
是的。
I don’t want to [inaudible 00:01:11].
我不想 [听不清 00:01:11]。
So what is Nitro?
那么什么是硝基呢?
01:11 It’s just got a lot of caffeine or something?
只是含有大量咖啡因或其他什么吗?
Don’t ask questions.
不要问问题。
01:13 It’s called Nitro.
它被称为硝基。
Do you need to know anything else?
您还需要了解其他信息吗?
It’s got nitrogen in it.
里面有氮气。
01:17 That’s ridiculous.
这太荒谬了。
What we breathe is 78% nitrogen anyway.
无论如何,我们呼吸的是 78% 的氮气。
What do you need to add more for?
你还需要添加更多做什么?
01:24 Unfortunately, you’re going to eat it.
不幸的是,你会吃掉它。
01:29 Most people think that they’re breathing oxygen and they’re actually breathing 78% nitrogen.
大多数人认为他们呼吸的是氧气,但实际上他们呼吸的是 78% 的氮气。
You need like a milk bar, like from Clockwork Orange.
你需要像发条橙那样的牛奶吧。
Yeah.
是的。
01:41 Yeah.
是的。
Is that the top three Kubrick film for you?
这是您心目中排名前三的库布里克电影吗?
Clockwork Orange?
发条橙?
01:44 It’s pretty good.
非常好。
It’s demented.
这是疯狂的。
Jarring, I’d say.
我想说,很刺耳。
Okay.
好的。
01:49 Okay.
好的。
So, first, let’s step back, and big congrats on getting Neuralink implanted into a human.
所以,首先,让我们退一步,热烈祝贺 Neuralink 被植入人体。
That’s a historic step for Neuralink.
这对 Neuralink 来说是历史性的一步。
Thanks.
谢谢。
Yeah.
是的。
And there’s many more to come.
还有更多的事情即将发生。
Yeah.
是的。
02:07 And we just obviously have our second implant as well.
显然我们也有第二个植入物。
How did that go?
进展如何?
So far, so good.
到目前为止,一切都很好。
02:12 It looks like we’ve got, I think, on the order of 400 electrodes that are providing signals.
我认为,我们似乎拥有大约 400 个提供信号的电极。
Nice.
好的。
Yeah.
是的。
How quickly do you think the number of human participants will scale?
您认为人类参与者的数量会多快扩大?
It depends somewhat on the regulatory approval, the rate at which we get regulatory approvals.
这在一定程度上取决于监管部门的批准,以及我们获得监管部门批准的速度。
02:28 So, we’re hoping to do 10 by the end of this year, total of 10.
所以,我们希望在今年年底前完成 10 个,总共 10 个。
So, eight more.
那么,还有八个。
And with each one, you’re going to be learning a lot of lessons about the neurobiology of the brain, everything.
在每一本书中,你都将学到很多关于大脑神经生物学的课程,一切。
02:42 The whole chain of the Neuralink, the decoding, the signal processing, all that kind of stuff.
Neuralink 的整个链条,解码,信号处理,所有这些东西。
Yeah.
是的。
02:54 Yeah.
是的。
I think it’s obviously going to get better with each one.
我认为显然每一个都会变得更好。
I don’t want to jinx it, but it seems to have gone extremely well with the second implant.
我不想给它带来厄运,但第二次植入似乎进展得非常好。
So, there’s a lot of signal, a lot of electrodes.
所以,有很多信号,很多电极。
It’s working very well.
它运作得很好。
What improvements do you think we’ll see in Neuralink in the coming, let’s say, let’s get crazy, the coming years.
您认为未来几年我们会在 Neuralink 中看到哪些改进,让我们疯狂一下吧。
In years, it’s going to be gigantic, because we’ll increase the number of electrodes dramatically.
几年后,它将会变得巨大,因为我们将大幅增加电极的数量。
03:18 We’ll improve the signal processing.
我们将改进信号处理。
So, even with only roughly, I don’t know, 10, 15% of the electrodes working with Noland, with our first patient, we were able to get to achieve a bit per second.
因此,即使只有大约(我不知道)10%、15% 的电极与 Noland 配合使用,我们的第一个患者也能够达到每秒一点的速度。
That’s twice the world record.
这是世界纪录的两倍。
So, I think we’ll start vastly exceeding the world record by orders of magnitude in the years to come.
因此,我认为我们将在未来几年开始大大超过世界纪录几个数量级。
So, start getting to, I don’t know, 100 bits per second, thousand.
所以,开始达到,我不知道,每秒 100 位,千位。
Maybe if five years from now, we might be at a megabit, faster than any human could possibly communicate by typing, or speaking.
也许五年后,我们的速度可能会达到兆位,比任何人通过打字或说话进行交流的速度都要快。
Yeah.
是的。
04:06 That BPS is an interesting metric to measure.
BPS 是一个有趣的衡量指标。
There might be a big leap in the experience once you reach a certain level of BPS.
一旦您达到一定的 BPS 水平,体验可能会有很大的飞跃。
Yeah.
是的。
Like entire new ways of interacting with a computer might be unlocked.
就像与计算机交互的全新方式可能会被解锁一样。
And with humans.
和人类。
With other humans.
与其他人类。
Provided they have want a Neuralink, too.
前提是他们也想要 Neuralink。
Right.
正确的。
Otherwise they wont be able to absorb the signals fast enough.
否则他们将无法足够快地吸收信号。
Do you think they’ll improve the quality of intellectual discourse?
您认为它们会提高知识分子话语的质量吗?
Well, I think you could think of it, if you were to slow down communication, how do you feel about that?
嗯,我想你可以想一下,如果你放慢沟通速度,你感觉如何?
04:34 If you’d only talk at, let’s say one-tenth of normal speed, you’d be like, “Wow, that’s agonizingly slow.”
如果你只以正常速度的十分之一说话,你会说,“哇,太慢了。”
Yeah.
是的。
So, now imagine you could communicate clearly at 10, or 100, or 1,000 times faster than normal.
所以,现在想象一下,您可以以比平常快 10 倍、100 倍或 1,000 倍的速度进行清晰的沟通。
Listen, I’m pretty sure nobody in their right mind listens to me at 1X.
听着,我很确定没有一个头脑正常的人会在 1X 听我说话。
05:00 they listen at 2X.
他们以 2X 的速度收听。
I can only imagine what 10X would feel like, or I could actually understand it.
我只能想象10X会是什么样的感觉,或者我实际上可以理解它。
I usually default to 1.5X.
我通常默认为1.5X。
05:14 You can do 2X.
你可以做2X。
Well actually, if I’m listening to somebody get to…
好吧,实际上,如果我正在听某人说话……
in 15, 20 minutes, I want to go to sleep, then I’ll do it 1.5X.
15、20 分钟后,我想睡觉,然后我会做 1.5 次。
If I’m paying attention, I’ll do 2X.
如果我注意的话,我会做 2 次。
Right.
正确的。
But actually, if you actually listen to podcasts, or audiobooks or anything at…
但实际上,如果你真的听播客、有声读物或其他任何东西......
05:32 If you get used to doing it at 1.5, then one sounds painfully slow.
如果您习惯以 1.5 进行操作,那么听起来会慢得令人痛苦。
I’m still holding onto one, because I’m afraid, I’m afraid of myself becoming bored with the reality, with the real world, where everyone’s speaking in 1X.
我仍然坚持着一个,因为我害怕,我害怕自己对现实、对现实世界感到厌倦,每个人都在用 1X 说话。
Well, it depends on the person.
嗯,这取决于人。
05:53 You can speak very fast.
你可以说得很快。
Like we can communicate very quickly.
就像我们可以很快沟通一样。
And also, if you use a wide range of…
而且,如果您使用多种……
if your vocabulary is larger, your effective bit rate is higher.
如果您的词汇量越大,您的有效比特率就越高。
That’s a good way to put it.
这是一个很好的表达方式。
Yeah.
是的。
The effective bit rate.
有效比特率。
06:07 That is the question, is how much information is actually compressed in the low bit transfer of language?
这就是问题,在语言的低位传输中实际上压缩了多少信息?
Yeah.
是的。
06:15 If there’s a single word that is able to convey something that would normally require, I don’t know, 10 simple words, then you’ve got maybe a 10X compression on your hands.
如果有一个单词能够传达通常需要(我不知道)10 个简单单词的内容,那么您可能会得到 10 倍的压缩。
And that’s really like with memes.
这真的很像模因。
Memes are like data compression.
模因就像数据压缩。
You’re simultaneously hit with a wide range of symbols that you can interpret, and you get it faster than if it were words, or a simple picture.
你同时会遇到各种各样可以解释的符号,而且你比文字或简单的图片更快地理解它。
And of course, you’re referring to memes broadly like ideas.
当然,你指的是模因,就像想法一样。
Yeah.
是的。
06:52 There’s an entire idea structure that is like an idea template, and then you can add something to that idea template.
有一个完整的想法结构,就像一个想法模板,然后您可以向该想法模板添加一些内容。
But somebody has that pre-existing idea template in their head.
但有些人的头脑中已有预先存在的想法模板。
So, when you add that incremental bit of information, you’re conveying much more than if you just said a few words.
因此,当您添加增量信息时,您传达的信息比只说几句话要多得多。
It’s everything associated with that meme.
这是与该模因相关的一切。
You think there’ll be emergent leaps of capability as you scale the number of electrodes?
您认为随着电极数量的增加,能力会出现突飞猛进吗?
Yeah.
是的。
Do you think there’ll be an actual number where just the human experience will be altered?
你认为会有一个实际数字改变人类的体验吗?
Yes.
是的。
What do you think that number might be?
你认为这个数字可能是多少?
07:27 Whether electrodes, or BPS?
是电极,还是BPS?
We of course, don’t know for sure, but is this 10,000, 100,000?
我们当然不确定,但是这是一万还是十万?
Yeah.
是的。
07:37 Certainly, if you’re anywhere at 10,000 bits per second, that’s vastly faster than any human can communicate right now.
当然,如果您处于每秒 10,000 位的速度,这比任何人类现在的通信速度都要快得多。
If you think what is the average bits per second of a human, it is less than one bit per second over the course of a day.
如果您想一下人类每秒的平均比特数是多少,那么一天中每秒的平均比特数还不到 1 比特。
Because there are 86,400 seconds in a day, and you don’t communicate 86,400 tokens in a day.
因为一天有 86,400 秒,而你一天不交流 86,400 个代币。
Therefore, your bits per second is less than one, averaged over 24 hours.
因此,24 小时内平均每秒的比特数小于 1。
It’s quite slow.
这很慢。
08:04 And now, even if you’re communicating very quickly, and you’re talking to somebody who understands what you’re saying, because in order to communicate, you have to at least to some degree, model the mind state of the person to whom you’re speaking.
现在,即使你的沟通速度非常快,并且你正在与一个理解你所说内容的人交谈,因为为了沟通,你必须至少在某种程度上模拟与你交谈的人的心理状态。
Then take the concept you’re trying to convey, compress that into a small number of syllables, speak them, and hope that the other person decompresses them into a conceptual structure that is as close to what you have in your mind as possible.
然后将你想要传达的概念压缩成几个音节,说出它们,并希望对方将它们解压成一个尽可能接近你脑海中的概念结构。
Yeah.
是的。
08:34 There’s a lot of signal loss there in that process.
在此过程中存在大量信号丢失。
Yeah.
是的。
08:37 Very lossy, compression, and decompression.
非常有损,压缩,解压缩。
And a lot of what your neurons are doing is distilling the concepts down to a small number of symbols, or say syllables that I’m speaking, or keystrokes, whatever the case may be.
你的神经元正在做的很多事情是将概念提炼成少量符号,或者说我正在说的音节,或者击键,无论是什么情况。
So, that’s a lot of what your brain computation is doing.
所以,这就是你的大脑计算正在做的很多事情。
Now, there is an argument that that’s actually a healthy thing to do, or a helpful thing to do because as you try to compress complex concepts, you’re perhaps forced to distill what is most essential in those concepts, as opposed to just all the fluff.
现在,有一种观点认为,这实际上是一件健康的事情,或者是一件有用的事情,因为当你试图压缩复杂的概念时,你可能被迫提炼出这些概念中最本质的东西,而不是所有的废话。
So, in the process of compression, you distill things down to what matters the most, because you can only say a few things.
所以,在压缩的过程中,你将事情提炼为最重要的事情,因为你只能说几件事。
09:27 So that is perhaps helpful.
所以这也许是有帮助的。
I think we’ll probably get…
我想我们可能会得到……
If our data rate increases, it’s highly probable it will become far more verbose.
如果我们的数据速率增加,它很可能会变得更加冗长。
Just like your computer, when computers had…
就像你的电脑一样,当电脑有...
My first computer had 8K of RAM, so you really thought about every byte.
我的第一台计算机有 8K RAM,所以你真的考虑到了每个字节。
And now you’ve got computers with many gigabytes of RAM.
现在您已经拥有了具有许多 GB RAM 的计算机。
So, if you want to do an iPhone app that just says, “Hello world,” it’s probably, I don’t know, several megabytes minimum, a bunch of fluff.
所以,如果你想做一个 iPhone 应用程序,只说“Hello world”,我不知道,它可能至少有几兆字节,一堆废话。
But nonetheless, we still prefer to have the computer with the more memory and more compute.
但尽管如此,我们仍然更喜欢拥有更多内存和更多计算能力的计算机。
10:09 So, the long-term aspiration of Neuralink is to improve the AI human symbiosis by increasing the bandwidth of the communication.
因此,Neuralink 的长期愿望是通过增加通信带宽来改善 AI 人类共生。
Because even if…
因为即使……
In the most benign scenario of AI, you have to consider that the AI is simply going to get bored waiting for you to spit out a few words.
在人工智能最良性的情况下,你必须考虑到人工智能只是会无聊地等待你吐出几句话。
If the AI can communicate at terabits per second, and you’re communicating at bits per second, it’s like talking to a tree.
如果人工智能能够以每秒太比特的速度进行通信,而你也以每秒比特的速度进行通信,那么就像与一棵树交谈一样。
Well, it is a very interesting question for a super intelligent species, what use are humans?
那么,对于一个超级智慧物种来说,这是一个非常有趣的问题,人类有什么用呢?
I think there is some argument for humans as a source of will.
我认为人类作为意志的来源是有争议的。
Will?
将要?
Will, yeah.
威尔,是的。
11:00 Source of will, or purpose.
意志或目的的来源。
So if you consider the human mind as being…
因此,如果你认为人类的思想是……
Essentially there’s the primitive, limbic elements, which basically even reptiles have.
本质上是原始的边缘元素,基本上连爬行动物也有。
And there’s the cortex, the thinking and planning part of the brain.
还有皮质,大脑的思考和计划部分。
Now, the cortex is much smarter than the limbic system, and yet is largely in service to the limbic system.
现在,皮质比边缘系统聪明得多,但主要为边缘系统服务。
It’s trying to make the limbic system happy.
它试图让边缘系统快乐。
The sheer amount of compute that’s gone into people trying to get laid is insane, without actually seeking procreation.
人们在试图上床时投入的计算量是疯狂的,而不是真正寻求生育。
They’re just literally trying to do this simple motion, and they get a kick out of it.
他们只是在尝试做这个简单的动作,并且从中得到了乐趣。
So, this simple, which in the abstract, rather absurd motion, which is sex, the cortex is putting a massive amount of compute into trying to figure out how to do that.
所以,这个简单的、抽象的、相当荒谬的运动,即性,皮层正在投入大量的计算来试图弄清楚如何做到这一点。
So like 90% of distributed compute of the human species is spent on trying to get laid, probably.
因此,人类 90% 的分布式计算可能都花在了上床上。
11:55 A large percentage.
很大比例。
A massive amount.
数量巨大。
12:00 Yes.
是的。
Yeah.
是的。
Yeah.
是的。
There’s no purpose to most sex except hedonistic.
大多数性行为除了享乐之外没有任何目的。
It’s a sort of joy, or whatever, dopamine release.
这是一种快乐,或者无论如何,多巴胺的释放。
Now, once in a while, it’s procreation, but for modern humans, it’s mostly recreational.
现在,偶尔,它是繁殖,但对于现代人类来说,它主要是娱乐。
And so, your cortex, much smarter than your limbic system, is trying to make the limbic system happy, because the limbic system wants to have sex, or wants some tasty food, or whatever the case may be.
因此,你的大脑皮层比边缘系统聪明得多,它正在努力让边缘系统快乐,因为边缘系统想要做爱,或者想要一些美味的食物,或者无论是什么情况。
12:31 And then that is then further augmented by the tertiary system, which is your phone, your laptop, iPad, whatever, all your computing stuff.
然后,第三系统进一步增强了这一点,第三系统是你的手机、你的笔记本电脑、iPad,等等,你所有的计算设备。
That’s your tertiary layer.
那是你的第三层。
So, you’re actually already a cyborg.
所以,你实际上已经是一个机器人了。
You have this tertiary compute layer, which is in the form of your computer with all the applications, or your compute devices.
您拥有这个第三计算层,它的形式是带有所有应用程序的计算机或计算设备。
And so, in the getting laid front, there’s actually a massive amount of digital compute also trying to get laid, with Tinder and whatever.
因此,在上床方面,实际上有大量的数字计算也试图通过 Tinder 等上床。
Yeah.
是的。
13:04 So, the compute that we humans have built is also participating.
因此,我们人类构建的计算也在参与。
Yeah.
是的。
13:09 There’s like gigawatts of compute going into getting laid, of digital compute.
大约有千兆瓦的数字计算投入使用。
Yeah.
是的。
13:14 What if AGI was-
如果 AGI 是——
This is happening as we speak.
就在我们说话的时候,这一切正在发生。
…
……
13:19 if we merge with AI, it’s just going to expand the compute that we humans use-
如果我们与人工智能合并,它只会扩展我们人类使用的计算能力——
Pretty much.
差不多了。
…
……
13:24 to try to get laid.
尝试上床。
Well, it’s one of the things.
嗯,这是其中之一。
13:25 Certainly, yeah.
当然,是的。
Yeah.
是的。
But what I’m saying is that, yes, is there a use for humans?
但我想说的是,是的,人类有什么用处吗?
13:29 Well, there’s this fundamental question of what’s the meaning of life?
好吧,有一个基本问题:生命的意义是什么?
Why do anything at all?
为什么要做任何事情?
And so, if our simple limbic system provides a source of will to do something, that then goes through our cortex, that then goes to our tertiary compute layer, then I don’t know, it might actually be that the AI, in a benign scenario, is simply trying to make the human limbic system happy.
因此,如果我们简单的边缘系统提供了做某事的意愿来源,然后穿过我们的皮层,然后进入我们的第三计算层,那么我不知道,在良性的情况下,人工智能实际上可能只是试图让人类边缘系统快乐。
Yeah.
是的。
14:03 It seems like the will is not just about the limbic system.
看来意志不仅仅与边缘系统有关。
There’s a lot of interesting, complicated things in there.
里面有很多有趣、复杂的东西。
We also want power.
我们也想要权力。
That’s limbic too, I think.
我认为这也是边缘系统。
But then we also want to, in a kind of cooperative way, alleviate the suffering in the world.
但我们也想以一种合作的方式减轻世界上的苦难。
Not everybody does.
不是每个人都这样。
14:19 But yeah, sure, some people do.
但是,是的,当然,有些人会这样做。
As a group of humans, when we get together, we start to have this kind of collective intelligence that is more complex in its will than the underlying individual descendants of apes, right?
作为一个人类群体,当我们聚集在一起时,我们开始拥有这种集体智慧,其意志比猿类的潜在个体后代更复杂,对吗?
Sure.
当然。
So there’s other motivations, and that could be a really interesting source of an objective function for AGI?
那么还有其他动机,这可能是 AGI 目标函数的一个非常有趣的来源?
Yeah.
是的。
14:45 There are these fairly cerebral, or higher level goals.
有这些相当理智的或更高层次的目标。
For me, it’s like, what’s the meaning of life, or understanding the nature of the universe, is of great interest to me, and hopefully to the AI.
对我来说,生命的意义是什么,或者理解宇宙的本质是什么,对我很感兴趣,希望对人工智能也很感兴趣。
And that’s the mission of xAI and Grok is understand the universe.
这就是 xAI 和 Grok 的使命:了解宇宙。
So do you think people…
那么你认为人们...
15:13 When you have a Neuralink with 10,000, 100,000 channels, most of the use cases will be communication with AI systems?
当你拥有一个具有 10,000、100,000 个通道的 Neuralink 时,大多数用例将是与 AI 系统通信?
Well, assuming that there are not…
好吧,假设没有……
15:27 They’re solving basic neurological issues that people have.
他们正在解决人们所面临的基本神经问题。
If they’ve got damaged neurons in their spinal cord, or neck, as is the case with our first two patients, then obviously the first order of business is solving fundamental neuron damage in a spinal cord, neck, or in the brain itself.
如果他们的脊髓或颈部神经元受损,就像我们前两名患者的情况一样,那么显然首要任务是解决脊髓、颈部或大脑本身的基本神经元损伤。
So, our second product is called Blindsight, which is to enable people who are completely blind, lost both eyes, or optic nerve, or just can’t see at all, to be able to see by directly triggering the neurons in the visual cortex.
所以,我们的第二个产品叫Blindsight,它是让那些完全失明、失去双眼、失去视神经、或者根本看不见的人,能够通过直接触发视觉皮层的神经元来看到东西。
16:18 So we’re just starting at the basics here, so it’s the simple stuff, relatively speaking, is solving neuron damage.
所以我们只是从基础开始,所以相对而言,解决神经元损伤是简单的事情。
It can also solve I think probably schizophrenia, if people have seizures of some kind, it could probably solve that.
我认为它还可以解决精神分裂症,如果人们有某种癫痫发作,它可能可以解决这个问题。
It could help with memory.
它可以帮助记忆。
So, there’s kind of a tech tree, if you will.
所以,如果你愿意的话,有一种科技树。
You’ve got the basics.
你已经掌握了基础知识。
You need literacy before you can have Lord of the Rings.
在拥有《指环王》之前,你需要识字。
Got it.
知道了。
So, do you have letters and the alphabet?
那么,你有字母和字母表吗?
17:02 Okay, great.
好的,太好了。
Words?
字?
And then eventually you get sagas.
然后最终你会得到传奇。
So, I think there may be some things to worry about in the future, but the first several years are really just solving basic neurological damage, like for people who have essentially complete or near complete loss from the brain to the body, like Stephen Hawking would be an example, the Neuralink would be incredibly profound, because you can imagine if Stephen Hawking could communicate as fast as we’re communicating, perhaps faster.
所以,我认为未来可能会有一些事情需要担心,但最初的几年实际上只是解决基本的神经损伤,就像对于那些从大脑到身体基本上完全或接近完全丧失的人来说,像史蒂芬·霍金就是一个例子,Neuralink 将是非常深刻的,因为你可以想象如果史蒂芬·霍金能够像我们一样快速地沟通,甚至更快。
And that’s certainly possible.
这当然是可能的。
Probable, in fact.
事实上,有可能。
Likely, I’d say.
我想说,有可能。
So there’s a kind of dual track of medical and non-medical, meaning so everything you’ve talked about could be applied to people who are non-disabled in the future?
所以说是一种医疗和非医疗的双轨,也就是说你所说的一切都可以应用到未来的非残疾人身上?
The logical thing to do is…
合乎逻辑的事情是……
17:58 Sensible thing to do is to start off solving basic neuron damage issues.
明智的做法是从解决基本的神经元损伤问题开始。
Yes.
是的。
Because there’s obviously some risk with a new device.
因为新设备显然存在一些风险。
18:11 You can’t get the risk down to zero, it’s not possible.
你无法将风险降至零,这是不可能的。
So, you want to have the highest possible reward, given there’s a certain irreducible risk.
因此,考虑到存在一定的不可降低的风险,您希望获得尽可能高的回报。
And if somebody’s able to have a profound improvement in their communication, that’s worth the risk.
如果某人能够在沟通方面取得深刻的进步,那么冒险是值得的。
As you get the risk down.
当你降低风险时。
Yeah.
是的。
18:36 As you get the risk down.
当你降低风险时。
And once the risk is down to…
一旦风险降至……
If you have thousands of people that have been using it for years and the risk is minimal, then perhaps at that point you could consider saying, “Okay, let’s aim for augmentation.” Now, I think we’re actually going to aim for augmentation with people who have neuron damage.
如果你有成千上万的人多年来一直在使用它,并且风险很小,那么也许那时你可以考虑说:“好吧,让我们以增强为目标。”现在,我认为我们实际上的目标是对神经元受损的人进行增强。
So we’re not just aiming to give people the communication data rate equivalent to normal humans.
因此,我们的目标不仅仅是为人们提供与正常人相当的通信数据速率。
We’re aiming to give people who have…
我们的目标是为那些拥有……的人提供
A quadriplegic, or maybe have complete loss of the connection to the brain and body, a communication data rate that exceeds normal humans.
四肢瘫痪,或者可能完全失去了大脑和身体的连接,通信数据速率超过了正常人。
While we’re in there, why not?
当我们在那里时,为什么不呢?
Let’s give people superpowers.
让我们赋予人们超能力。
And the same for vision.
视力也是如此。
19:20 As you restore vision, there could be aspects of that restoration that are superhuman.
当您恢复视力时,恢复的某些方面可能是超人的。
Yeah.
是的。
19:27 At first, the vision restoration will be low res, because you have to say, “How many neurons can you put in there, and trigger?” And you can do things where you adjust the electric field.
首先,视力恢复将是低分辨率的,因为你必须说,“你可以在那里放置多少个神经元并触发?”你可以做一些调整电场的事情。
So, even if you’ve got, say 10,000 neurons, it’s not just 10,000 pixels, because you can adjust the field between the neurons, and do them in patterns in order to have say, 10,000 electrodes, effectively give you, I don’t know, maybe like having a megapixel, or a 10 megapixel situation.
所以,即使你有,比如说 10,000 个神经元,它也不仅仅是 10,000 个像素,因为你可以调整神经元之间的场,并以某种模式进行它们,以便有说,10,000 个电极,有效地给你,我不知道,也许就像拥有一个百万像素或一个 10 兆像素的情况。
And then over time, I think you get to higher resolution than human eyes.
随着时间的推移,我认为你会获得比人眼更高的分辨率。
And you could also see in different wavelengths.
你还可以看到不同波长的东西。
So, like Geordi La Forge from Star Trek, he had the thing.
所以,就像《星际迷航》中的乔迪·拉·福吉(Geordi La Forge)一样,他拥有这样的东西。
Do you want to see it in radar?
你想在雷达上看到它吗?
No problem.
没问题。
You could see ultraviolet, infrared, eagle vision, whatever you want.
你可以看到紫外线、红外线、鹰眼视觉,任何你想要的东西。
Do you think there’ll be…
你觉得会有吗……
20:28 let me ask a Joe Rogan question.
让我问乔·罗根一个问题。
Do you think there’ll be…
你觉得会有吗……
I just recently have taken ayahuasca.
我最近刚刚服用死藤水。
Is that a serious question?
这是一个严肃的问题吗?
No.
不。
20:38 Well, yes.
嗯,是的。
Well, I guess technically it is.
嗯,我想从技术上来说是这样的。
Yeah.
是的。
Yeah.
是的。
Ever try DMT bro?
兄弟试过DMT吗?
Yeah, is this DMT in there, or something?
是啊,里面有DMT吗?
Love you, Joe.
爱你,乔。
20:42 Okay.
好的。
Wait, wait.
等等,等等。
20:48 Have you said much about it, the ayahuasca stuff?
你有没有说过很多有关死藤水的事?
I have not.
我没有。
I have not.
我没有。
I have not.
我没有。
Okay.
好的。
20:53 Well, why don’t you spill the beans?
好吧,你为什么不透露秘密呢?
It is a truly incredible experience.
这真是一次令人难以置信的经历。
Let me turn the tables on you.
让我来扭转局面。
Well, yeah.
嗯,是的。
You’re in the jungle.
你在丛林里。
Yeah, amongst the trees, myself and a shaman.
是的,在树林里,我和一个萨满。
Yeah.
是的。
21:02 It must’ve been crazy.
这一定是疯了。
Yeah, yeah, yeah.
是啊,是啊,是啊。
21:05 With the insects, with the animals all around you, the jungle as far as the eye can see, there’s no…
昆虫、动物在你身边,一望无际的丛林,没有……
That’s the way to do it.
这就是方法。
Things are going to look pretty wild.
事情看起来会非常疯狂。
Yeah, pretty wild.
是啊,相当狂野。
21:14 I took an extremely high dose.
我服用了极高的剂量。
Just don’t go hugging an Anaconda or something.
只是不要去拥抱蟒蛇之类的东西。
You haven’t lived unless you made love to an Anaconda.
除非你和蟒蛇做爱,否则你就不算活着。
21:24 I’m sorry, but…
抱歉,但是……
Snakes and Ladders.
蛇和梯子。
Yeah.
是的。
21:33 I took a extremely high dose.
我服用了极高的剂量。
Okay.
好的。
Nine cups.
九杯。
Damn.
该死。
21:39 Okay.
好的。
That sounds like a lot.
听起来很多。
Is normal to just one cup?
只喝一杯正常吗?
Or…
或者……
One or two.
一两个。
21:42 Usually one.
通常是一个。
Okay.
好的。
21:46 Wait.
等待。
Like right off the bat, or did you work your way up to it?
是一开始就这样,还是你自己努力做到的?
Did you just jump in at the deep end?
你刚刚跳进了深渊吗?
Across two days, because the first day, I took two, and it was a ride, but it wasn’t quite like a…
跨越两天,因为第一天,我坐了两次,这是一次骑行,但不太像……
It wasn’t like a revelation.
这不像是一个启示。
It wasn’t into deep space type of ride.
它不是深空类型的骑行。
22:01 It was just like a little airplane ride.
这就像坐一次小飞机一样。
And I [inaudible 00:22:07] saw some trees, and some visuals, and just saw a dragon and all that kind of stuff.
我 [听不清 00:22:07] 看到了一些树和一些视觉效果,还看到了一条龙和所有类似的东西。
But…
但是……
Nine cups, you went to Pluto, I think.
九杯,我想你去了冥王星。
Pluto.
冥王星。
22:15 Yeah.
是的。
No, Deep space.
不,深空。
Deep space.
深空。
One of the interesting aspects of my experience is I thought I would have some demons, some stuff to work through.
我的经历中一个有趣的方面是我认为我会有一些恶魔,一些需要解决的问题。
That’s what people [inaudible 00:22:26].
这就是人们的想法 [听不清 00:22:26]。
That’s what everyone says.
大家都是这么说的。
That’s what everyone says.
大家都是这么说的。
22:27 Yeah, exactly.
是的,完全正确。
I had nothing.
我什么都没有。
22:29 I had all positive.
我的一切都是积极的。
I just…
我只是……
So full-
这么饱满——
Just a pure soul.
只是一个纯粹的灵魂。
I don’t think so.
我不这么认为。
22:32 I don’t know.
我不知道。
But I kept thinking about, I had extremely high resolution thoughts about the people I know in my life.
但我一直在想,我对我生命中认识的人有非常清晰的想法。
You were there, and it is just not from my relationship with that person, but just as the person themselves.
你在那里,这不是因为我和那个人的关系,而是因为那个人本身。
I had just this deep gratitude of who they are.
我对他们深表感激。
That’s cool.
这很酷。
It was just like this exploration, like Sims, or whatever.
就像这次探索,就像模拟人生,或者其他什么。
22:53 You get to watch them.
你可以观察他们。
I got to watch people, and just be in awe of how amazing they are.
我必须观察人们,并对他们的惊人之处感到敬畏。
That sounds awesome.
听起来棒极了。
Yeah, it was great.
是的,太棒了。
23:02 I was waiting for-
我在等待——
When’s the demon coming?
恶魔什么时候来?
Exactly.
确切地。
23:07 Maybe I’ll have some negative thoughts.
也许我会有一些消极的想法。
Nothing.
没有什么。
Nothing.
没有什么。
Just extreme gratitude for them.
只是对他们表示万分的感谢。
And also a lot of space travel.
还有很多太空旅行。
Space travel to where?
太空旅行去哪里?
So here’s what it was.
事情就是这样。
23:20 It was people, the human beings that I know, they had this kind of…
是人,我所认识的人类,他们有这样的……
The best way I could describe it is they had a glow to them.
我能描述的最好的方式就是他们散发着光芒。
Okay.
好的。
And then I kept flying out from them to see earth, to see our solar system, to see our galaxy.
然后我不断地从他们那里飞出去,看看地球,看看我们的太阳系,看看我们的银河系。
23:30 And I saw that light, that glow all across the universe, whatever that form is, whatever that…
我看到了那道光,那光芒遍布整个宇宙,无论那是什么形式,无论那是什么……
Did you go past the Milky Way?
你穿过银河系了吗?
Yeah.
是的。
Okay.
好的。
23:53 You’re like intergalactic.
你就像星际一样。
Yeah, intergalactic.
是的,星际。
Okay.
好的。
23:55 Dang.
当当。
But always pointing in, yeah.
但总是指向,是的。
23:56 Past the Milky Way, past…
过去了银河系,过去了……
I mean, I saw a huge number of galaxies, intergalactic, and all of it was glowing, but I couldn’t control that travel, because I would actually explore near distances to the solar system, see if there’s aliens, or any of that kind of stuff.
我的意思是,我看到了大量的星系,星系间的星系,所有这些都在发光,但我无法控制这种旅行,因为我实际上会探索太阳系附近的距离,看看是否有外星人,或者任何类似的东西。
Sure.
当然。
Did you see an alien?
你看到外星人了吗?
No.
不。
24:14 I didn’t, no.
我没有,没有。
Zero aliens?
零外星人?
Implication of aliens, because they were glowing.
暗示外星人,因为他们会发光。
24:16 They were glowing in the same way that humans were glowing.
它们的发光方式与人类发光的方式相同。
That life force that I was seeing, the thing that made humans amazing was there throughout the universe.
我所看到的生命力,让人类惊叹的东西存在于整个宇宙中。
There was these glowing dots.
有这些发光的点。
So, I don’t know.
所以,我不知道。
It made me feel like there is life…
这让我觉得还有生命……
No, not life, but something, whatever makes humans amazing all throughout the universe.
不,不是生命,而是某种东西,任何让人类在整个宇宙中令人惊叹的东西。
Sounds good.
听起来不错。
Yeah, it was amazing.
是的,太棒了。
24:42 No demons.
没有恶魔。
No demons.
没有恶魔。
I looked for the demons.
我寻找恶魔。
There’s no demons.
没有恶魔。
There were dragons, and they’re pretty awesome.
有龙,而且它们非常可怕。
So the thing about trees-
那么关于树的事情-
Was there anything scary at all?
有什么可怕的吗?
Dragons.
龙。
24:54 But they weren’t scary.
但他们并不可怕。
They were friends.
他们是朋友。
They were protective.
他们是保护性的。
So, the thing is-
所以,事情是——
Sure.
当然。
24:57 Like Puff the Magic Dragon.
比如魔龙帕夫。
No, it was more like a Game of Thrones kind of dragons.
不,它更像是权力的游戏中的龙。
24:58 They weren’t very friendly.
他们不太友好。
They were very big.
它们很大。
So the thing is that bought giant trees, at night, which is where I was-
所以事情是在晚上买了参天大树,这就是我所在的地方——
Yeah.
是的。
25:09 I mean, the jungle’s kind of scary.
我的意思是,丛林有点可怕。
Yeah.
是的。
25:10 The trees started to look like dragons, and they were all looking at me.
树木开始看起来像龙,它们都在看着我。
Sure.
当然。
25:15 Okay.
好的。
And it didn’t seem scary.
而且看起来并不可怕。
25:17 They seemed like they were protecting me.
他们看起来就像是在保护我。
And the shaman and the people didn’t speak any English, by the way, which made it even scarier, because we’re not even…
顺便说一下,萨满和人们不会说任何英语,这让它更可怕,因为我们甚至不……
We’re worlds apart in many ways, but yeah, they talk about the mother of the forest protecting you, and that’s what I felt like.
我们在很多方面都有天壤之别,但是,是的,他们谈论森林之母保护你,这就是我的感受。
And you were way out in the jungle.
而你却身处丛林之中。
Way out.
出路。
25:40 This is not like a tourist retreat.
这不像是一个旅游胜地。
Like 10 miles outside of Rio or something.
比如距离里约热内卢 10 英里之类的地方。
No, we went…
不,我们去了……
25:47 No, this is not a-
不,这不是——
You’re in deep Amazon.
你在亚马逊深处。
Me and this guy named Paul Rosolie, who basically is a Tarzan, he lives in the jungle, we went out deep and we just went crazy.
我和这个叫保罗·罗索利(Paul Rosolie)的人,他基本上是泰山,他住在丛林里,我们深入深处,我们简直疯了。
Wow.
哇。
25:59 Cool.
凉爽的。
Yeah.
是的。
26:01 So anyway.
所以无论如何。
Can I get that same experience in a Neuralink?
我可以在 Neuralink 中获得同样的体验吗?
Probably.
大概。
26:04 Yeah.
是的。
I guess that is the question for non-disabled people.
我想这就是非残疾人的问题。
26:05 Do you think that there’s a lot in our perception, in our experience of the world that could be explored, that could be played with, using Neuralink?
您是否认为我们的感知、我们对世界的体验中有很多东西可以使用 Neuralink 来探索、玩转?
Yeah, I mean, Neuralink, it’s really a generalized input-output device.
是的,我的意思是,Neuralink,它确实是一个通用的输入输出设备。
26:18 It’s reading electrical signals, and generating electrical signals, and I mean, everything that you’ve ever experienced in your whole life, smell, emotions, all of those are electrical signals.
它正在读取电信号,并生成电信号,我的意思是,你一生中经历过的一切,气味,情绪,所有这些都是电信号。
So, it’s kind of weird to think that your entire life experience is distilled down to electrical signals for neurons, but that is in fact the case.
因此,认为你的整个生活经历都被归结为神经元的电信号有点奇怪,但事实确实如此。
Or I mean, that’s at least what all the evidence points to.
或者我的意思是,至少所有证据都表明了这一点。
So, I mean, if you trigger the right neuron, you could trigger a particular scent.
所以,我的意思是,如果你触发正确的神经元,你就可以触发一种特定的气味。
You could certainly make things glow.
你当然可以让事物发光。
I mean, do pretty much anything.
我的意思是,做几乎任何事情。
I mean, really, you can think of the brain as a biological computer.
我的意思是,实际上,你可以将大脑视为一台生物计算机。
So, if there are certain say, chips or elements of that biological computer that are broken, let’s say your ability to…
所以,如果生物计算机的某些芯片或元件损坏了,比如说你有能力……
If you’ve got a stroke, that if you’ve had a stroke, that means some part of your brain is damaged.
如果你中风了,那就意味着你大脑的某些部分受损了。
Let’s say it’s speech generation, or the ability to move your left hand.
假设它是语音生成,或者移动左手的能力。
That’s the kind of thing that a Neuralink could solve.
这就是 Neuralink 可以解决的问题。
27:33 If you’ve got a massive amount of memory loss that’s just gone, well, we can’t get the memories back.
如果你的记忆大量丧失,而且刚刚消失,那么我们就无法恢复记忆。
We could restore your ability to make memories, but we can’t restore memories that are fully gone.
我们可以恢复你创造记忆的能力,但我们无法恢复完全消失的记忆。
Now, I should say, maybe if part of the memory is there, and the means of accessing the memory is the part that’s broken, then we could re-enable the ability to access the memory.
现在,我应该说,也许如果部分内存还存在,并且访问内存的方式是损坏的部分,那么我们可以重新启用访问内存的能力。
But you can think of it like ram in a computer, if the ram is destroyed, or your SD card is destroyed, we can’t get that back.
但你可以把它想象成电脑中的内存,如果内存被破坏,或者你的SD卡被破坏,我们就无法恢复它。
But if the connection to the SD card is destroyed, we can fix that.
但如果与 SD 卡的连接被破坏,我们可以修复它。
If it is fixable physically, then it can be fixed.
如果物理上可以修复,那么就可以修复。
Of course, with AI, just like you can repair photographs, and fill in missing parts of photographs, maybe you can do the same, just like [inaudible 00:28:31] parts.
当然,有了人工智能,就像你可以修复照片,填补照片中缺失的部分一样,也许你也可以做同样的事情,就像[听不清 00:28:31] 的部分。
Yeah, you could say like, create the most probable set of memories based on all the information you have about that person.
是的,你可以说,根据你拥有的关于那个人的所有信息创建最可能的一组记忆。
28:30 You could then…
那么你可以……
It would be probabilistic restoration of memory.
这将是记忆的概率恢复。
Now, we’re getting pretty esoteric here.
现在,我们在这里变得非常深奥。
But that is one of the most beautiful aspects of the human experience is remembering the good memories.
但人类经历中最美丽的方面之一就是记住美好的回忆。
Sure.
当然。
We live most of our life, as Danny Kahneman has talked about, in our memories, not in the actual moment.
正如丹尼·卡尼曼所说,我们一生的大部分时间都生活在我们的记忆中,而不是现实的时刻。
28:53 We’re collecting memories and we kind of relive them in our head.
我们正在收集记忆,并在脑海中重温它们。
And that’s the good times.
那就是美好时光。
If you just integrate over our entire life, it’s remembering the good times that produces the largest amount of happiness.
如果你把我们的一生融为一体,记住美好时光就会产生最大的幸福。
Yeah.
是的。
29:11 Well, I mean, what are we but our memories?
好吧,我的意思是,除了我们的记忆之外,我们还算什么呢?
And what is death?
什么是死亡?
But the loss of memory, loss of information?
但失去记忆、失去信息呢?
If you could say, well, if you could run a thought experiment, what if you were disintegrated painlessly, and then reintegrated a moment later, like teleportation, I guess?
如果你可以说,好吧,如果你可以进行一个思想实验,如果你被无痛地解体,然后片刻后重新整合,我猜,就像瞬间传送一样,会怎么样?
Provided there’s no information loss, the fact that your one body was disintegrated is irrelevant.
只要没有信息丢失,你的身体被解体这一事实就无关紧要了。
And memories is just such a huge part of that.
记忆只是其中很大一部分。
Death is fundamentally the loss of information, the loss of memory.
死亡从根本上来说就是信息的丢失、记忆的丢失。
So, if we can store them as accurately as possible, we basically achieve a kind of immortality.
所以,如果我们能够尽可能准确地存储它们,我们基本上就实现了一种永生。
Yeah.
是的。
You’ve talked about the threats, the safety concerns of AI.
您谈到了人工智能的威胁和安全问题。
29:57 Let’s look at long-term visions.
让我们看看长期愿景。
Do you think Neuralink is, in your view, the best current approach we have for AI safety?
在您看来,Neuralink 是我们当前实现人工智能安全的最佳方法吗?
It’s an idea that may help with AI safety.
这个想法可能有助于人工智能安全。
30:13 Certainly, I wouldn’t want to claim it’s some panacea, or that it’s a sure thing, but I mean, many years ago I was thinking like, “Well, what would inhibit alignment of collective human will with artificial intelligence?” And the low data rate of humans, especially our slow output rate would necessarily, just because the communication is so slow, would diminish the link between humans and computers.
当然,我不想声称它是某种灵丹妙药,或者这是肯定的事情,但我的意思是,很多年前我就在想,“那么,什么会阻碍人类集体意志与人工智能的结合呢?”人类的低数据速率,尤其是我们缓慢的输出速率,仅仅因为通信太慢,必然会削弱人类和计算机之间的联系。
The more you are a tree, the less you know what the tree is.
你越是一棵树,你就越不知道树是什么。
Let’s say you look at this plant or whatever, and hey, I’d really like to make that plant happy, but it’s not saying a lot.
假设你看着这种植物或其他什么,嘿,我真的很想让那种植物快乐,但这并没有说明太多。
So the more we increase the data rate that humans can intake and output, then that means the better, the higher the chance we have in a world full of AGI’s.
因此,我们提高人类接收和输出的数据速率越多,就意味着我们在一个充满 AGI 的世界中拥有的机会就越好,机会就越大。
Yeah.
是的。
31:21 We could better align collective human will with AI if the output rate especially was dramatically increased.
如果产出率大幅提高,我们就可以更好地将人类集体意志与人工智能结合起来。
And I think there’s potential to increase the output rate by, I don’t know, three, maybe six, maybe more orders of magnitude.
我认为有可能将产出率提高三个,也许六个,也许更多数量级,我不知道。
So, it’s better than the current situation.
所以,比现在的情况要好一些。
And that output rate would be by increasing the number of electrodes, number of channels, and also maybe implanting multiple Neuralinks?
输出率是通过增加电极数量、通道数量,也可能是植入多个 Neuralink 来实现?
Yeah.
是的。
Do you think there’ll be a world in the next couple of decades where it’s hundreds of millions of people have Neuralinks?
您认为未来几十年内会有一个数亿人拥有 Neuralink 的世界吗?
Yeah, I do.
是的,我愿意。
You think when people just when they see the capabilities, the superhuman capabilities that are possible, and then the safety is demonstrated.
你认为,当人们看到能力、可能的超人能力时,然后就会证明安全性。
Yeah.
是的。
32:11 If it’s extremely safe, and you can have superhuman abilities, and let’s say you can upload your memories, so you wouldn’t lose memories, then I think probably a lot of people would choose to have it.
如果它非常安全,而且你可以拥有超人的能力,比如说你可以上传你的记忆,这样你就不会丢失记忆,那么我想可能很多人都会选择拥有它。
It would supersede the cell phone, for example.
例如,它将取代手机。
I mean, the biggest problem that say, a phone has, is trying to figure out what you want.
我的意思是,手机最大的问题是试图弄清楚你想要什么。
That’s why you’ve got auto complete, and you’ve got output, which is all the pixels on the screen, but from the perspective of the human, the output is so frigging slow.
这就是为什么你有自动完成功能,并且有输出,即屏幕上的所有像素,但从人类的角度来看,输出太慢了。
Desktop or phone is desperately just trying to understand what you want.
台式电脑或手机正在拼命地试图了解您想要什么。
And there’s an eternity between every keystroke from a computer standpoint.
从计算机的角度来看,每次击键之间都有一个永恒的时间。
Yeah.
是的。
33:06 Yeah.
是的。
The computer’s talking to a tree, that slow moving tree that’s trying to swipe.
计算机正在与一棵树对话,这棵树移动缓慢,试图滑动。
Yeah.
是的。
33:12 So, if you had computers that are doing trillions of instructions per second, and a whole second went by, I mean, that’s a trillion things it could have done.
所以,如果你的计算机每秒执行数万亿条指令,并且一整秒过去了,我的意思是,它可以完成万亿次的事情。
Yeah.
是的。
33:24 I think it’s exciting, and scary for people, because once you have a very high bit rate, it changes the human experience in a way that’s very hard to imagine.
我认为这对人们来说既令人兴奋又令人恐惧,因为一旦拥有非常高的比特率,它就会以一种难以想象的方式改变人类的体验。
Yeah.
是的。
33:35 We would be something different.
我们会有所不同。
I mean, some sort of futuristic cyborg, I mean, we’re obviously talking about, by the way, it’s not like around the corner.
我的意思是,某种未来派的机器人,我的意思是,我们显然正在谈论,顺便说一句,它并不是指日可待。
You asked me what the distant future is.
你问我遥远的未来是什么。
Maybe this is…
也许这就是……
It’s not super far away, but 10, 15 years, that kind of thing.
并不是很遥远,但是10年、15年之类的事情。
When can I get one?
我什么时候可以得到一个?
33:58 10 years?
10年?
Probably less than 10 years.
大概不到10年。
34:02 It depends on what you want to do.
这取决于你想做什么。
Hey, if I can get a thousand BPS?
嘿,如果我能得到一千个 BPS 吗?
A thousand BPS, wow.
一千 BPS,哇。
And it’s safe, and I can just interact with a computer while laying back and eating Cheetos.
而且它很安全,我可以一边躺着吃奇多一边与电脑互动。
34:12 I don’t eat Cheetos.
我不吃奇多。
There’s certain aspects of human computer interaction when done more efficiently, and more enjoyably, are worth it.
当人机交互的某些方面做得更高效、更愉快时,是值得的。
Well, we feel pretty confident that I think maybe within the next year or two, that someone with a Neuralink implant will be able to outperform a pro gamer.
好吧,我们非常有信心,我认为也许在未来一两年内,植入 Neuralink 的人将能够超越职业玩家。
Nice.
好的。
Because the reaction time would be faster.
因为反应时间会更快。
I got to visit Memphis.
我得去孟菲斯看看。
Yeah.
是的。
34:46 Yeah.
是的。
You’re going big on compute.
您正在大力发展计算。
Yeah.
是的。
And you’ve also said, “Play to win, or don’t play at all.”
你也说过,“为了胜利而打球,或者干脆不打球。”
Yeah.
是的。
So what does it take to win?
那么,怎样才能获胜呢?
For AI, that means you’ve got to have the most powerful training compute, and the rate of improvement of training compute has to be-
对于人工智能来说,这意味着你必须拥有最强大的训练计算,并且训练计算的改进率必须是-
35:00 And the rate of improvement of training compute has to be faster than everyone else, or you will not win.
而且训练计算的提升速度必须比其他人快,否则你就赢不了。
Your AI will be worse.
你的人工智能会更糟。
So how can Grok, let’s say 3…
那么 Grok 怎样才能做到,比方说 3……
35:10 That might be available, what, next year?
那可能是可用的,什么,明年?
Well, hopefully end of this year.
嗯,希望今年年底。
Grok 3.
格罗克 3.
If we’re lucky.
如果我们幸运的话。
35:17 Yeah.
是的。
How can that be the best LLM, the best AI system available in the world?
这怎么可能是世界上最好的法学硕士、最好的人工智能系统呢?
35:20 How much of it is compute?
其中有多少是计算的?
How much of it is data?
其中有多少是数据?
How much of it is post-training?
其中有多少是后期培训的?
How much of it is the product that you package it up in, all that kind of stuff?
诸如此类的东西,其中有多少是你包装的产品?
I mean, they all matter.
我的意思是,它们都很重要。
35:35 It’s sort of like saying, let’s say it’s a Formula 1 race, what matters more, the car or the driver?
这有点像在说,假设这是一场一级方程式比赛,赛车和车手哪个更重要?
I mean, they both matter.
我的意思是,它们都很重要。
If a car is not fast, then if, let’s say, it’s half the horsepower of your competitors, the best driver will still lose.
如果一辆汽车速度不快,那么如果它的马力只有竞争对手的一半,那么最好的车手仍然会失败。
If it’s twice the horsepower, then probably even a mediocre driver will still win.
如果马力是两倍,那么即使是平庸的车手也可能会获胜。
So, the training compute is kind of like the engine, this horsepower of the engine.
所以,训练计算有点像引擎,引擎的马力。
So, really, you want to try to do the best on that.
所以,真的,你想尽力做到最好。
And then, it’s how efficiently do you use that training compute, and how efficiently do you do the inference, the use of the AI?
然后,问题是你使用训练计算的效率如何,以及你进行推理、人工智能的使用的效率如何?
So, obviously, that comes down to human talent.
所以,显然,这取决于人才。
And then, what unique access to data do you have?
然后,您对数据有什么独特的访问权限?
That also plays a role.
这也发挥了作用。
Do you think Twitter data will be useful?
您认为 Twitter 数据有用吗?
Yeah.
是的。
36:31 I mean, I think most of the leading AI companies have already scraped all the Twitter data.
我的意思是,我认为大多数领先的人工智能公司已经抓取了所有 Twitter 数据。
Not I think.
我认为不是。
They have.
他们有。
So, on a go forward basis, what’s useful is the fact that it’s up to the second, because that’s hard for them to scrape in real time.
因此,从长远来看,有用的是它取决于第二个事实,因为这对他们来说很难实时抓取。
So, there’s an immediacy advantage that Grok has already.
因此,Grok 已经具备了即时优势。
I think with Tesla and the real time video coming from several million cars, ultimately tens of millions of cars with Optimus, there might be hundreds of millions of Optimus robots, maybe billions, learning a tremendous amount from the real world.
我认为,有了特斯拉以及来自数百万辆汽车(最终是数千万辆配备 Optimus 的汽车)的实时视频,可能会有数亿甚至数十亿个 Optimus 机器人从现实世界中学习大量知识。
That’s the biggest source of data, I think, ultimately, is Optimus, probably.
我认为,最终,最大的数据来源可能是 Optimus。
Optimus is going to be the biggest source of data.
Optimus 将成为最大的数据源。
Because it’s able to-
因为它能够——
Because reality scales.
因为现实是有尺度的。
37:22 Reality scales to the scale of reality.
现实规模与现实规模成正比。
It’s actually humbling to see how little data humans have actually been able to accumulate.
看到人类实际上能够积累的数据如此之少,实际上令人感到羞愧。
Really, if you say how many trillions of usable tokens have humans generated, where on a non-duplicative…
真的,如果你说人类生成了多少万亿个可用代币,在非重复的情况下......
Discounting spam and repetitive stuff, it’s not a huge number.
扣除垃圾邮件和重复的内容,这个数字并不是很大。
You run out pretty quickly.
你很快就用完了。
And Optimus can go…
擎天柱可以去……
37:54 So, Tesla cars, unfortunately, have to stay on the road.
因此,不幸的是,特斯拉汽车必须继续上路。
Right.
正确的。
Optimus robot can go anywhere.
擎天柱机器人可以去任何地方。
38:01 And there’s more reality off the road.
还有更多的现实正在发生。
And go off-road.
并越野。
Yeah.
是的。
38:06 I mean, the Optimus robot can pick up the cup and see, did it pick up the cup in the right way?
我的意思是,擎天柱机器人可以拿起杯子,看看它是否以正确的方式拿起杯子?
Did it, say, go pour water in the cup?
它是说,往杯子里倒水吗?
Did the water go in the cup or not go in the cups?
水进了杯子还是没进杯子?
Did it spill water or not?
水洒了还是没洒?
Simple stuff like that.
诸如此类的简单事情。
But it can do that at scale times a billion, so generate useful data from reality, so cause and effect stuff.
但它可以在十亿倍的规模上做到这一点,因此可以从现实中生成有用的数据,以及因果关系。
What do you think it takes to get to mass production of humanoid robots like that?
您认为如何才能大规模生产这样的人形机器人?
It’s the same as cars, really.
这真的和汽车一样。
38:40 I mean, global capacity for vehicles is about 100 million a year, and it could be higher.
我的意思是,全球汽车产能每年约为 1 亿辆,而且可能会更高。
It’s just that the demand is on the order of 100 million a year.
只是每年的需求量在亿个量级。
And then, there’s roughly two billion vehicles that are in use in some way, which makes sense because the life of a vehicle is about 20 years.
然后,大约有 20 亿辆汽车以某种方式在使用,这是有道理的,因为汽车的使用寿命约为 20 年。
So, at steady state, you can have 100 million vehicles produced a year with a two billion vehicle fleet, roughly.
因此,在稳定状态下,每年可以生产 1 亿辆汽车,拥有大约 20 亿辆汽车。
Now, for humanoid robots, the utility is much greater.
现在,对于人形机器人来说,效用要大得多。
So, my guess is humanoid robots are more like at a billion plus per year.
所以,我的猜测是,人形机器人每年的数量可能超过十亿。
But until you came along and started building Optimus, it was thought to be an extremely difficult problem.
但直到你出现并开始构建擎天柱之前,这被认为是一个极其困难的问题。
Well, I think it is.
嗯,我想是的。
I mean, it still is an extremely difficult problem.
我的意思是,这仍然是一个极其困难的问题。
Yes.
是的。
39:28 So, a walk in the park.
于是,去公园散步。
I mean, Optimus, currently, would struggle to walk in the park.
我的意思是,擎天柱目前在公园里走路很困难。
I mean, it can walk in a park.
我的意思是,它可以在公园里散步。
The park is not too difficult, but it will be able to walk over a wide range of terrain.
公园难度不算太大,但是能走的地形范围很广。
Yeah.
是的。
39:43 And pick up objects.
并捡起物体。
Yeah, yeah.
是啊是啊。
39:45 It can already do that.
它已经可以做到这一点。
But all kinds of objects.
但各种物体。
Yeah, yeah.
是啊是啊。
All foreign objects.
所有异物。
39:50 I mean, pouring water in a cup is not trivial, because then if you don’t know anything about the container, it could be all kinds of containers.
我的意思是,将水倒入杯子中并不是一件小事,因为如果你对容器一无所知,那么它可能是各种容器。
Yeah, there’s going to be an immense amount of engineering just going into the hand.
是的,将会有大量的工程工作投入到手中。
39:59 The hand, it might be close to half of all the engineering in Optimus.
这只手,可能接近擎天柱所有工程的一半。
From an electromechanical standpoint, the hand is probably roughly half of the engineering.
从机电的角度来看,手可能大约占工程的一半。
But so much of the intelligence of humans goes into what we do with our hands.
但人类的大部分智慧都体现在我们用手所做的事情上。
Yeah.
是的。
It’s the manipulation of the world, manipulation of objects in the world.
这是对世界的操纵,对世界上物体的操纵。
40:22 Intelligent, safe manipulation of objects in the world.
智能、安全地操控世界上的物体。
Yeah.
是的。
Yeah.
是的。
40:28 I mean, you start really thinking about your hand and how it works.
我的意思是,你开始真正思考你的手以及它是如何运作的。
I do all the time.
我一直都这样做。
The sensory control homunculus is where you have humongous hands.
感觉控制小人就是你拥有巨大双手的地方。
40:35 So I mean, your hands, the actuators, the muscles of your hand are almost overwhelmingly in your forearm.
所以我的意思是,你的手、执行器、你手上的肌肉几乎绝大多数都在你的前臂上。
So, your forearm has the muscles that actually control your hand.
所以,你的前臂有真正控制你的手的肌肉。
There’s a few small muscles in the hand itself, but your hand is really like a skeleton meat puppet and with cables.
手本身有一些小肌肉,但你的手真的就像一个骷髅肉傀儡,有电缆。
So, the muscles that control your fingers are in your forearm, and they go through the carpal tunnel, which is that you’ve got a little collection of bones and a tiny tunnel that these cables, the tendons go through, and those tendons are mostly what move your hands.
所以,控制你手指的肌肉在你的前臂,它们穿过腕管,腕管里有一些骨头和一条小隧道,这些电缆、肌腱穿过这些隧道,而这些肌腱主要是移动你的手的。
And something like those tendons has to be re-engineered into the Optimus in order to do all that kind of stuff.
像这些肌腱这样的东西必须重新设计到擎天柱中才能完成所有这些事情。
Yeah.
是的。
41:26 So the current Optimus, we tried putting the actuators in the hand itself.
所以目前的擎天柱,我们尝试将执行器放在手上。
Then you sort of end up having these-
然后你最终会得到这些-
Giant hands?
巨手?
…
……
41:34 yeah, giant hands that look weird.
是的,巨大的手看起来很奇怪。
And then, they don’t actually have enough degrees of freedom or enough strength.
然后,他们实际上没有足够的自由度或足够的力量。
So then you realize, “Oh, okay, that’s why you got to put the actuators in the forearm.” And just like a human, you’ve got to run cables through a narrow tunnel to operate the fingers.
然后你意识到,“哦,好吧,这就是为什么你必须把执行器放在前臂上。”就像人类一样,你必须将电缆穿过狭窄的隧道来操作手指。
And then, there’s also a reason for not having all the fingers the same length.
此外,所有手指的长度不一样也是有原因的。
So, it wouldn’t be expensive from an energy or evolutionary standpoint to have all your fingers be the same length.
因此,从能量或进化的角度来看,让所有手指长度相同并不昂贵。
So, why not do the same length?
那么,为什么不做同样的长度呢?
Yeah, why not?
是啊,为什么不呢?
Because it’s actually better to have different lengths.
因为实际上有不同的长度更好。
42:04 Your dexterity is better if you’ve got fingers that are different lengths.
如果您的手指长度不同,您的灵活性会更好。
There are more things you can do and your dexterity is actually better if your fingers are a different length.
如果您的手指长度不同,您可以做的事情会更多,而且您的灵活性实际上会更好。
There’s a reason we’ve got a little finger.
我们有小手指是有原因的。
Why not have a little finger that’s bigger?
为什么没有一个更大的小指呢?
Yeah.
是的。
Because it helps you with fine motor skills.
因为它可以帮助您培养精细运动技能。
This little finger helps?
这个小指有用吗?
It does.
确实如此。
42:28 But if you lost your little finger, you’d have noticeably less dexterity.
但如果你失去了小指,你的灵活性就会明显下降。
So, as you’re figuring out this problem, you have to also figure out a way to do it so you can mass manufacture it, so as to be as simple as possible.
所以,当你解决这个问题时,你还必须找到一种方法来实现它,这样你就可以批量生产它,从而尽可能简单。
It’s actually going to be quite complicated.
实际上会非常复杂。
42:42 The as possible part is it’s quite a high bar.
尽可能的部分是它的门槛相当高。
If you want to have a humanoid robot that can do things that a human can do, actually, it’s a very high bar.
如果你想拥有一个能做人类能做的事情的人形机器人,实际上这是一个非常高的门槛。
So, our new arm has 22 degrees of freedom instead of 11 and has, like I said, the actuators in the forearm.
因此,我们的新手臂有 22 个自由度,而不是 11 个自由度,并且正如我所说,执行器位于前臂中。
And all the actuators are designed from scratch, from physics first principles.
所有执行器都是根据物理学第一原理从头开始设计的。
The sensors are all designed from scratch.
传感器都是从头开始设计的。
And we’ll continue to put a tremendous amount of engineering effort into improving the hand.
我们将继续投入大量的工程努力来改进手部。
By hand, I mean the entire forearm, from elbow forward, is really the hand.
我所说的手,是指从肘部向前的整个前臂,实际上就是手。
So, that’s incredibly difficult engineering, actually.
所以,这实际上是一项非常困难的工程。
And so, the simplest possible version of a humanoid robot that can do even most, perhaps not all, of what a human can do is actually still very complicated.
因此,最简单的人形机器人版本实际上仍然非常复杂,它甚至可以完成人类所能做的大部分(也许不是全部)工作。
It’s not simple.
这并不简单。
It’s very difficult.
这是非常困难的。
Can you just speak to what it takes for a great engineering team for you?
您能谈谈对您来说优秀的工程团队需要什么吗?
43:47 What I saw in Memphis, the supercomputer cluster, is just this intense drive towards simplifying the process, understanding the process, constantly improving it, constantly iterating it.
我在孟菲斯超级计算机集群中看到的正是这种简化流程、理解流程、不断改进、不断迭代的强烈动力。
Well, it’s easy to say ‘simplify,’ and it’s very difficult to do it.
“简化”说起来容易,做起来却很难。
44:08 I have this very basic first principles algorithm that I run kind of as a mantra, which is to first question the requirements, make the requirements less dumb.
我有一个非常基本的第一原理算法,我将其作为口头禅运行,即首先质疑需求,使需求不那么愚蠢。
The requirements are always dumb to some degree.
在某种程度上,要求总是愚蠢的。
So, you want to start off by reducing the number of requirements, and no matter how smart the person is who gave you those requirements, they’re still dumb to some degree.
因此,你想从减少要求的数量开始,无论提出这些要求的人多么聪明,他们在某种程度上仍然是愚蠢的。
You have to start there, because, otherwise, you could get the perfect answer to the wrong question.
你必须从那里开始,因为否则你可能会得到错误问题的完美答案。
So, try to make the question the least wrong possible.
所以,尽量让问题尽可能少出错。
That’s what question the requirements means.
这就是需求的意义所在。
44:53 And then, the second thing is try to delete whatever the step is, the part or the process step.
然后,第二件事是尝试删除任何步骤、零件或流程步骤。
It sounds very obvious, but people often forget to try deleting it entirely.
这听起来很明显,但人们经常忘记尝试完全删除它。
And if you’re not forced to put back at least 10% of what you delete, you’re not deleting enough.
如果您没有被迫恢复至少 10% 的删除内容,那么您删除的内容还不够。
Somewhat illogically, people often, most of the time, feel as though they’ve succeeded if they’ve not been forced to put things back in.
有点不合逻辑的是,大多数时候,人们常常觉得,如果他们没有被迫把事情放回去,他们就已经成功了。
But, actually, they haven’t because they’ve been overly conservative and have left things in there that shouldn’t be.
但实际上,他们没有这样做,因为他们过于保守,留下了不该留下的东西。
And only the third thing is try to optimize it or simplify it.
只有第三件事是尝试优化它或简化它。
Again, these all sound, I think, very obvious when I say them, but the number of times I’ve made these mistakes is more than I care to remember.
再说一次,我认为,当我说这些话时,这些听起来都非常明显,但我犯这些错误的次数多得我记不清了。
That’s why I have this mantra.
这就是为什么我有这个咒语。
So in fact, I’d say the most common mistake of smart engineers is to optimize a thing that should not exist.
所以事实上,我想说聪明的工程师最常犯的错误就是优化了一个不应该存在的东西。
Right.
正确的。
46:01 So, like you say, you run through the algorithm and basically show up to a problem, show up to the supercomputer cluster, and see the process, and ask, “Can this be deleted?”
所以,就像你说的,你运行算法,基本上会出现一个问题,出现在超级计算机集群上,看到进程,然后问,“这个可以删除吗?”
Yeah.
是的。
46:14 First try to delete it.
首先尝试删除它。
Yeah.
是的。
Yeah.
是的。
46:18 That’s not easy to do.
这并不容易做到。
No.
不。
46:20 Actually, what generally makes people uneasy is that at least some of the things that you delete, you will put back in.
事实上,通常让人不安的是,至少有一些你删除的东西,你又会放回去。
But going back to sort of where our limbic system can steer us wrong is that we tend to remember, with sometimes a jarring level of pain, where we deleted something that we subsequently needed.
但回到我们的边缘系统可能引导我们错误的地方,我们往往会记住,有时会感到非常痛苦,我们删除了我们随后需要的东西。
And so, people will remember that one time they forgot to put in this thing three years ago, and that caused them trouble.
所以,人们会记得三年前有一次他们忘记放这个东西,这给他们带来了麻烦。
And so, they overcorrect, and then they put too much stuff in there and overcomplicate things.
因此,他们矫枉过正,然后他们放了太多东西,让事情变得过于复杂。
So, you actually have to say, “Look, we’re deliberately going to delete more than we should.” At least one in 10 things, we’re going to add back in.
所以,你实际上必须说,“看,我们故意删除比我们应该删除的更多的内容。”至少十分之一的事情,我们会重新添加。
I’ve seen you suggest just that, that something should be deleted, and you can kind of see the pain.
我看到你建议应该删除一些东西,你可以看到其中的痛苦。
Oh, yeah.
哦,是的。
47:18 Absolutely.
绝对地。
Everybody feels a little bit of the pain.
每个人都感到一点点痛苦。
Absolutely.
绝对地。
47:21 And I tell them in advance, “Yeah, some of the things that we delete, we’re going to put back in.” People get a little shook by that, but it makes sense because if you’re so conservative as to never have to put anything back in, you obviously have a lot of stuff that isn’t needed.
我提前告诉他们,“是的,我们删除的一些东西,我们会放回去。”人们对此感到有点震惊,但这是有道理的,因为如果你如此保守以至于永远不需要放回任何东西,那么你显然有很多不需要的东西。
So, you got to overcorrect.
所以,你必须矫枉过正。
This is, I would say, like a cortical override to a limbic instinct.
我想说,这就像皮质超越边缘本能。
One of many that probably leads us astray.
其中之一可能会让我们误入歧途。
Yeah.
是的。
47:50 There’s a step four as well, which is any given thing can be sped up.
还有第四步,即任何给定的事情都可以加快。
However fast you think it can be done, whatever the speed it’s being done, it can be done faster.
无论你认为它能以多快的速度完成,无论它的完成速度如何,它都可以做得更快。
But you shouldn’t speed things up until you’ve tried to delete it and optimize.
但在尝试删除它并优化之前,您不应该加快速度。
Although, you’re speeding up something that…
虽然,你正在加速某些事情……
Speeding up something that shouldn’t exist is absurd.
加速不应该存在的事情是荒谬的。
48:09 And then, the fifth thing is to automate it.
然后,第五件事是自动化。
I’ve gone backwards so many times where I’ve automated something, sped it up, simplified it, and then deleted it.
我已经倒退过很多次了,我自动化了一些东西,加速了它,简化了它,然后删除了它。
And I got tired of doing that.
我厌倦了这样做。
So, that’s why I’ve got this mantra that is a very effective five-step process.
所以,这就是为什么我有这个口头禅,这是一个非常有效的五步过程。
It works great.
效果很好。
Well, when you’ve already automated, deleting must be real painful-
好吧,当你已经自动化时,删除一定是非常痛苦的——
Yeah.
是的。
…
……
48:35 as if you’ve [inaudible 00:48:36]-
就好像你已经[听不清 00:48:36]-
Yeah, it’s very.
是的,非常。
48:36 It’s like, “Wow, I really wasted a lot of effort there.”
就像,“哇,我真的在那里浪费了很多精力。”
Yeah.
是的。
48:40 I mean, what you’ve done with the cluster in Memphis is incredible, just in a handful of weeks.
我的意思是,仅仅几周的时间,你们在孟菲斯的集群上所做的事情就令人难以置信。
Well, yeah, it’s not working yet, so I don’t want to pop the champagne corks.
嗯,是的,它还没有起作用,所以我不想打开香槟瓶塞。
48:47 In fact, I have a call in a few hours with the Memphis team because we’re having some power fluctuation issues.
事实上,几个小时后我就接到了孟菲斯团队的电话,因为我们遇到了一些电力波动问题。
So yeah, when you do synchronized training, when you have all these computers that are training, where the training is synchronized at the millisecond level, it’s like having an orchestra.
所以,是的,当你进行同步训练时,当你拥有所有这些正在训练的计算机时,训练以毫秒级同步,就像有一个管弦乐队一样。
And the orchestra can go loud to silent very quickly at subsecond level, and then, the electrical system freaks out about that.
管弦乐队可以在亚秒级快速从大声到静音,然后,电气系统就会对此感到恐慌。
If you suddenly see giant shifts, 10, 20 megawatts several times a second, this is not what electrical systems are expecting to see.
如果您突然看到每秒几次 10、20 兆瓦的巨大变化,这不是电力系统所期望看到的。
So, that’s one of the main things you have to figure out, the cooling, the power.
所以,这是你必须弄清楚的主要问题之一:冷却和电源。
49:46 And then, on the software, as you go up the stack, how to do the distributed compute, all of that.
然后,在软件上,当你进入堆栈时,如何进行分布式计算,所有这些。
All of that has to work.
所有这些都必须发挥作用。
Yeah.
是的。
49:56 So, today’s problem is dealing with extreme power jitter.
因此,今天的问题是处理极端的功率抖动。
Power jitter.
电源抖动。
Yeah.
是的。
There’s a nice ring to that.
这是一个很好的戒指。
50:03 Okay.
好的。
And you stayed up late into the night, as you often do there.
你熬夜到深夜,就像你在那里经常做的那样。
Last week.
上星期。
50:11 Yeah.
是的。
Last week.
上星期。
Yeah.
是的。
Yeah.
是的。
50:14 We finally got training going at, oddly enough, roughly 4:20 a.m.
奇怪的是,我们终于在凌晨 4 点 20 分左右开始训练。
last Monday.
上周一。
Total coincidence.
完全巧合。
Yeah.
是的。
50:25 I mean, maybe it was at 4:22 or something.
我的意思是,也许是在 4 点 22 分左右。
Yeah, yeah, yeah.
是啊,是啊,是啊。
Yeah.
是的。
It’s that universe again with the jokes.
又是那个充满笑话的宇宙了。
Well, exactly.
嗯,确实如此。
50:29 It just loves it.
它只是喜欢它。
I mean, I wonder if you could speak to the fact that one of the things that you did when I was there is you went through all the steps of what everybody’s doing, just to get a sense that you yourself understand it and everybody understands it so they can understand when something is dumb, or something is inefficient, or that kind of stuff.
我的意思是,我想知道你是否能说出这样一个事实:我在那里时你所做的一件事就是你经历了每个人正在做的事情的所有步骤,只是为了感觉到你自己理解它并且每个人都理解它,这样他们就能理解什么时候有些事情是愚蠢的,或者有些事情效率低下,或者诸如此类的事情。
50:31 Can you speak to that?
你能谈谈吗?
Yeah.
是的。
50:52 So, look, whatever the people at the front lines are doing, I try to do it at least a few times myself.
所以,看,无论前线的人们在做什么,我自己至少尝试做几次。
So connecting fiber optic cables, diagnosing a faulty connection.
因此连接光纤电缆,诊断连接错误。
That tends to be the limiting factor for large training clusters is the cabling.
布线往往是大型训练集群的限制因素。
There’s so many cables.
有这么多电缆。
For a coherent training system, where you’ve got RDMA, remote direct memory access, the whole thing is like one giant brain.
对于一个具有 RDMA(远程直接内存访问)的连贯训练系统,整个系统就像一个巨大的大脑。
So, you’ve got any-to-any connection.
因此,您拥有任意对任意的连接。
So, any GPU can talk to any GPU out of 100,000.
因此,任何 GPU 都可以与 100,000 个 GPU 中的任何一个进行通信。
That is a crazy cable layout.
这是一个疯狂的电缆布局。
It looks pretty cool.
看起来很酷。
Yeah.
是的。
It’s like the human brain, but at a scale that humans can visibly see.
它就像人类的大脑,但其规模是人类可以肉眼看到的。
51:40 It is a good brain.
这是一个好大脑。
Yeah.
是的。
51:47 But, I mean, the human brain also has…
但是,我的意思是,人脑也有……
A massive amount of the brain tissue is the cables.
大量的脑组织是电缆。
So they get the gray matter, which is the compute, and then the white matter, which is cables.
所以他们得到灰质,即计算,然后是白质,即电缆。
A big percentage of your brain is just cables.
你大脑的很大一部分只是电缆。
That’s what it felt like walking around in the supercomputer center is like we’re walking around inside a brain that will one day build a super, super intelligent system.
这就是在超级计算机中心走来走去的感觉,就像我们在大脑中走动一样,有一天会构建一个超级、超级智能的系统。
52:01 Do you think there’s a chance that xAI, that you are the one that builds AGI?
你认为 xAI 有可能是你构建 AGI 的人吗?
It’s possible.
这是可能的。
52:22 What do you define as AGI?
你对 AGI 的定义是什么?
I think humans will never acknowledge that AGI has been built.
我认为人类永远不会承认通用人工智能已经建成。
Just keep moving the goalposts?
只是继续移动球门柱吗?
Yeah.
是的。
52:33 So, I think there’s already superhuman capabilities that are available in AI systems.
所以,我认为人工智能系统已经具备了超人的能力。
Oh, yeah.
哦,是的。
I think what AGI is is when it’s smarter than the collective intelligence of the entire human species in our [inaudible 00:52:49].
我认为 AGI 比我们整个人类的集体智慧还要聪明 [听不清 00:52:49]。
Well, I think that, generally, people would call that ASI, artificial super intelligence.
嗯,我认为,一般来说,人们会称之为 ASI,人工智能。
52:49 But there are these thresholds where you could say at some point the AI is smarter than any single human.
但存在这些阈值,在某些时候你可以说人工智能比任何一个人都聪明。
And then, you’ve got eight billion humans, and actually, each human is machine augmented via their computers.
然后,你有八十亿人,实际上,每个人都是通过他们的计算机进行机器增强的。
So, it’s a much higher bar to compete with eight billion machine augmented humans.
因此,与 80 亿机器增强人类竞争的门槛要高得多。
That’s a whole bunch of orders of magnitude more.
这要高出一大堆数量级。
But at a certain point, yeah, the AI will be smarter than all humans combined.
但在某个时刻,人工智能将比所有人类加起来还要聪明。
If you are the one to do it, do you feel the responsibility of that?
如果你是这样做的人,你觉得有责任吗?
Yeah, absolutely.
是的,绝对是。
53:35 And I want to be clear, let’s say if xAI is first, the others won’t be far behind.
我想澄清的是,如果 xAI 是第一,那么其他人也不会落后太多。
I mean, they might be six months behind, or a year, maybe.
我的意思是,他们可能会落后六个月,或者一年。
Not even that.
甚至不是这样。
So, how do you do it in a way that doesn’t hurt humanity, do you think?
那么,你认为如何才能以不伤害人类的方式做到这一点呢?
So, I mean, I thought about AI, essentially, for a long time, and the thing that at least my biological neural net comes up with as being the most important thing is adherence to truth, whether that truth is politically correct or not.
所以,我的意思是,我从本质上思考了人工智能很长一段时间,至少我的生物神经网络认为最重要的是坚持真理,无论这个真理在政治上是否正确。
54:00 So, I think if you force AIs to lie or train them to lie, you’re really asking for trouble, even if that lie is done with good intentions.
所以,我认为如果你强迫人工智能撒谎或训练他们撒谎,你真的是在自找麻烦,即使这个谎言是出于善意。
So, you saw issues with ChatGPT and Gemini and whatnot.
所以,您看到了 ChatGPT 和 Gemini 等问题。
Like, you asked Gemini for an image of the Founding Fathers of the United States, and it shows a group of diverse women.
比如,你向双子座要了一张美国开国元勋的照片,它展示了一群多元化的女性。
Now, that’s factually untrue.
现在看来,这实际上是不正确的。
54:48 Now, that’s sort of like a silly thing, but if an AI is programmed to say diversity is a necessary output function, and it then becomes this omnipowerful intelligence, it could say, “Okay, well, diversity is now required, and if there’s not enough diversity, those who don’t fit the diversity requirements will be executed.” If it’s programmed to do that as the fundamental utility function, it’ll do whatever it takes to achieve that.
现在,这有点像一件愚蠢的事情,但如果人工智能被编程为说多样性是必要的输出功能,然后它变成了这种无所不能的智能,它可以说,“好吧,现在需要多样性,如果没有足够的多样性,那些不符合多样性要求的人将被处决。”如果它被编程为将其作为基本效用函数,那么它将不惜一切代价来实现这一目标。
So, you have to be very careful about that.
所以,你必须非常小心。
That’s where I think you want to just be truthful.
这就是我认为你想要说实话的地方。
Rigorous adherence to the truth is very important.
严格遵守真理非常重要。
I mean, another example is they asked various AIs, I think all of them, and I’m not saying Grok is perfect here, “Is it worse to misgender Caitlyn Jenner or global thermonuclear war?” And it said it’s worse to misgender Caitlyn Jenner.
我的意思是,另一个例子是他们询问了各种人工智能,我想是所有的人工智能,我并不是说 Grok 在这里是完美的,“凯特琳·詹纳 (Caitlyn Jenner) 性别错误或全球热核战争更糟糕吗?”报告称,凯特琳·詹纳的性别错误更糟糕。
Now, even Caitlyn Jenner said, “Please misgender me.
现在,就连凯特琳·詹纳也说:“请误会我的性别。
That is insane.” But if you’ve got that kind of thing programmed in, the AI could conclude something absolutely insane like it’s better in order to avoid any possible misgendering, all humans must die, because then misgendering is not possible because there are no humans.
这太疯狂了。”但如果你把这种东西编入程序,人工智能可能会得出一些绝对疯狂的结论,比如为了避免任何可能的性别错误,最好是所有人类都必须死,因为这样就不可能出现性别错误,因为没有人类。
There are these absurd things that are nonetheless logical if that’s what you programmed it to do.
有些荒谬的事情尽管是合乎逻辑的,如果这就是你编程它要做的事情的话。
56:17 So in 2001 Space Odyssey, what Arthur C.
所以在《2001太空漫游》中,Arthur C.
Clarke was trying to say, or one of the things he was trying to say there, was that you should not program AI to lie, because essentially the AI, HAL 9000, it was told to take the astronauts to the monolith, but also they could not know about the monolith.
克拉克试图说的,或者他试图在那里说的一件事是,你不应该对人工智能进行编程来撒谎,因为从本质上讲,人工智能,HAL 9000,被告知要把宇航员带到巨石上,但他们也不可能知道巨石。
So, it concluded that it will kill them and take them to the monolith.
因此,它得出的结论是,它将杀死他们并将他们带到巨石上。
Thus, it brought them to the monolith.
因此,它把他们带到了巨石上。
They’re dead, but they do not know about the monolith.
他们死了,但他们不知道巨石的存在。
Problem solved.
问题解决了。
That is why it would not open the pod bay doors.
这就是为什么它不会打开吊舱门。
There’s a classic scene of, “Why doesn’t it want to open the pod bay doors?” They clearly weren’t good at prompt engineering.
有一个经典的场景,“为什么它不想打开吊舱门?”他们显然不擅长即时工程。
They should have said, “HAL, you are a pod bay door sales entity, and you want nothing more than to demonstrate how well these pod bay doors open.”
他们应该说:“HAL,您是吊舱门销售实体,您只想展示这些吊舱门的打开效果如何。”
Yeah.
是的。
57:16 The objective function has unintended consequences almost no matter what if you’re not very careful in designing that objective function, and even a slight ideological bias, like you’re saying, when backed by super intelligence, can do huge amounts of damage.
如果你在设计目标函数时不小心的话,几乎无论如何,目标函数都会产生意想不到的后果,甚至像你所说的那样,在超级智能的支持下,即使是轻微的意识形态偏见,也会造成巨大的损害。
Yeah.
是的。
But it’s not easy to remove that ideological bias.
但消除这种意识形态偏见并不容易。
57:31 You’re highlighting obvious, ridiculous examples, but-
你强调的是明显的、荒谬的例子,但是——
Yet they’re real examples of-
然而他们是真实的例子——
…
……
57:38 they’re real.
它们是真实的。
They’re real.
它们是真实的。
…
……
57:39 AI that was released to the public.
向公众发布的人工智能。
They are real.
它们是真实的。
That went through QA, presumably, and still said insane things, and produced insane images.
大概是经过了质量检查,但仍然说了一些疯狂的事情,并产生了疯狂的图像。
Yeah.
是的。
57:47 But you can swing the other way.
但你也可以换个方向。
Truth is not an easy thing.
真理并不是一件容易的事。
No, it’s not.
不,不是。
We kind of bake in ideological bias in all kinds of directions.
我们在各个方面都灌输了意识形态偏见。
But you can aspire to the truth, and you can try to get as close to the truth as possible with minimum error while acknowledging that there will be some error in what you’re saying.
但你可以追求真理,你可以尝试以最小的错误尽可能接近真理,同时承认你所说的可能存在一些错误。
57:57 So, this is how physics works.
所以,这就是物理学的运作原理。
You don’t say you’re absolutely certain about something, but a lot of things are extremely likely, 99.99999% likely to be true.
你不会说你对某件事绝对确定,但很多事情极有可能,99.99999% 的可能性是真的。
So, aspiring to the truth is very important.
所以,追求真理是非常重要的。
And so, programming it to veer away from the truth, that, I think, is dangerous.
因此,我认为,对其进行编程以偏离事实是危险的。
Right.
正确的。
58:32 Like, yeah, injecting our own human biases into the thing.
就像,是的,将我们自己的人类偏见注入其中。
Yeah.
是的。
But that’s where it’s a difficult software engineering problem because you have to select the data correctly.
但这就是一个困难的软件工程问题,因为你必须正确选择数据。
It’s hard.
这很难。
And the internet, at this point, is polluted with so much AI generated data, it’s insane.
而此时的互联网已经被如此多的人工智能生成的数据所污染,这太疯狂了。
58:44 Actually, there’s a thing now, if you want to search the internet, you can say, “Google, but exclude anything after 2023.” It will actually often give you better results because there’s so much.
实际上,现在有件事,如果你想在互联网上搜索,你可以说,“谷歌,但排除 2023 年之后的任何内容。”实际上,它通常会给你更好的结果,因为有太多的东西。
The explosion of AI generated material is crazy.
人工智能生成的材料的爆炸是疯狂的。
So in training Grok, we have to go through the data and say like, “Hey…” We actually have to apply AI to the data to say, “Is this data most likely correct or most likely not?” before we feed it into the training system.
因此,在训练 Grok 时,我们必须仔细检查数据并说,“嘿……”我们实际上必须将 AI 应用于数据来说,“这个数据最有可能是正确的还是最有可能不是?”在我们将其输入训练系统之前。
That’s crazy.
这太疯狂了。
59:28 Yeah.
是的。
And is it generated by human?
它是由人类产生的吗?
Yeah.
是的。
I mean, the data filtration process is extremely, extremely difficult.
我的意思是,数据过滤过程非常非常困难。
Yeah.
是的。
Do you think it’s possible to have a serious, objective, rigorous political discussion with Grok, like for a long time, like Grok 3 or Grok 4 or something?
你认为有可能与Grok进行严肃、客观、严格的政治讨论吗?像Grok 3或Grok 4之类的,像Grok 3或Grok 4这样的长期讨论?
Grok 3 is going to be next level.
Grok 3 将更上一层楼。
59:48 I mean, what people are currently seeing with Grok is kind of baby Grok.
我的意思是,人们目前看到的 Grok 是一种婴儿 Grok。
Yeah, baby Grok.
是的,宝贝格罗克。
It’s baby Grok right now.
现在是小格罗克。
59:55 But baby Grok is still pretty good.
不过格罗克宝宝还是很不错的。
But it’s an order of magnitude less sophisticated than GPT-4.
但它的复杂程度比 GPT-4 低一个数量级。
It’s now Grok 2, which finished training, I don’t know, six weeks ago or thereabouts.
现在是 Grok 2,我不知道,它在六周前左右完成了训练。
Grok 2 will be a giant improvement.
Grok 2 将是一个巨大的改进。
And then Grok 3 will be, I don’t know, order of magnitude better than Grok 2.
然后 Grok 3 将比 Grok 2 好几个数量级,我不知道。
And you’re hoping for it to be state-of-the-art better than-
你希望它比最先进的更好——
Hopefully.
希望如此。
1:00:25 I mean, this is the goal.
我的意思是,这就是目标。
I mean, we may fail at this goal.
我的意思是,我们可能无法实现这个目标。
That’s the aspiration.
这就是愿望。
Do you think it matters who builds the AGI, the people, and how they think, and how they structure their companies and all that kind of stuff?
你认为谁构建了 AGI、人员、他们的想法、他们如何构建公司以及诸如此类的东西重要吗?
Yeah.
是的。
1:00:42 I think it’s important that whatever AI wins, it’s a maximum truth seeking AI that is not forced to lie for political correctness, or, well, for any reason, really, political, anything.
我认为重要的是,无论人工智能获胜,它都是一个最大限度寻求真相的人工智能,不会被迫为政治正确性或出于任何原因而撒谎,实际上是政治上的任何原因。
I am concerned about AI succeeding that is programmed to lie, even in small ways.
我担心人工智能会成功,因为它被编程为撒谎,即使是在很小的方面。
Right.
正确的。
1:01:13 Because in small ways becomes big ways when it’s doing something-
因为当它做某事时,小事就会变成大事——
To become very big ways.
变得非常大。
1:01:17 Yeah.
是的。
And when it’s used more and more at scale by humans.
当它被人类越来越大规模地使用时。
Yeah.
是的。
Since I am interviewing Donald Trump-
因为我正在采访唐纳德·特朗普——
Cool.
酷。
…
……
1:01:28 you want to stop by?
你想过来吗?
Yeah, sure.
是的,当然。
I’ll stop in.
我会停下来。
There was, tragically, an assassination attempt on Donald Trump.
不幸的是,唐纳德·特朗普遭遇了一次暗杀企图。
1:01:30 After this, you tweeted that you endorse him.
此后,你在推特上表示你支持他。
What’s your philosophy behind that endorsement?
您的认可背后的理念是什么?
What do you hope Donald Trump does for the future of this country and for the future of humanity?
您希望唐纳德·特朗普为这个国家的未来和人类的未来做些什么?
Well, I think people tend to take, say, an endorsement as, well, I agree with everything that person has ever done their entire life 100% wholeheartedly, and that’s not going to be true of anyone.
嗯,我认为人们倾向于接受认可,因为,嗯,我百分百全心全意地同意这个人一生所做的一切,但对任何人来说都不是这样。
1:01:47 But we have to pick.
但我们必须选择。
We’ve got two choices, really, for who’s president.
对于谁当总统,我们实际上有两种选择。
And it’s not just who’s president, but the entire administrative structure changes over.
不仅仅是谁是总统,整个行政结构也发生了变化。
And I thought Trump displayed courage under fire, objectively.
客观地说,我认为特朗普在受到攻击时表现出了勇气。
He’s just got shot.
他刚刚被枪杀。
He’s got blood streaming down his face, and he’s fist pumping, saying, “Fight.” That’s impressive.
他的脸上流着血,他挥舞着拳头,说道:“战斗吧。”这令人印象深刻。
You can’t feign bravery in a situation like that.
在这种情况下你不能假装勇敢。
Most people would be ducking because there could be a second shooter.
大多数人都会躲开,因为可能会有第二个枪手。
You don’t know.
你不知道。
1:02:44 The president of the United States have got to represent the country, and they’re representing you.
美国总统必须代表国家,而他们也代表你们。
They’re representing everyone in America.
他们代表美国的每个人。
Well, I think you want someone who is strong and courageous to represent the country.
嗯,我认为你需要一个坚强而勇敢的人来代表国家。
That is not to say that he is without flaws.
这并不是说他没有缺点。
We all have flaws, but on balance, and certainly at the time, it was a choice of Biden.
我们都有缺点,但总的来说,当然在当时,这是拜登的选择。
Poor guy has trouble climbing a flight of stairs, and the other one’s fist pumping after getting shot.
可怜的家伙爬楼梯都困难,而另一个人中弹后拳头不断挥动。
So, there’s no comparison.
所以,没有可比性。
I mean, who do you want dealing with some of the toughest people and other world leaders who are pretty tough themselves?
我的意思是,你希望谁与一些最坚强的人和其他本身也很坚强的世界领导人打交道?
1:03:27 I mean, I’ll tell you one of the things that I think are important.
我的意思是,我会告诉你一件我认为重要的事情。
I think we want a secure border.
我认为我们想要一个安全的边界。
We don’t have a secure border.
我们没有安全的边界。
We want safe and clean cities.
我们想要安全、清洁的城市。
I think we want to reduce the amount of spending, at least slow down the spending, because we’re currently spending at a rate that is bankrupting the country.
我认为我们希望减少支出,至少减缓支出,因为我们目前的支出速度正在使国家破产。
The interest payments on US debt this year exceeded the entire defense department spending.
今年美国债务的利息支付超过了整个国防部的支出。
If this continues, all of the federal government taxes will simply be paying the interest.
如果这种情况持续下去,所有联邦政府税收都将只是支付利息。
1:04:06 And you keep going down that road, and you end up in the tragic situation that Argentina had back in the day.
如果你继续沿着这条路走下去,你最终就会陷入阿根廷当年所经历的悲惨境地。
Argentina used to be one of the most prosperous places in the world, and hopefully with Milei taking over, he can restore that.
阿根廷曾经是世界上最繁荣的国家之一,希望米雷接手后,他能恢复这一点。
But it was an incredible fall from grace for Argentina to go from being one of the most prosperous places in the world to being very far from that.
但对于阿根廷来说,从世界上最繁荣的国家之一变成了相距甚远,这是一次令人难以置信的失宠。
So, I think we should not take American prosperity for granted.
因此,我认为我们不应该认为美国的繁荣是理所当然的。
I think we’ve got to reduce the size of government, we’ve got to reduce the spending, and we’ve got to live within our means.
我认为我们必须缩小政府规模,我们必须减少开支,我们必须量入为出。
Do you think politicians, in general, politicians, governments…
你认为政治家,一般来说,政治家,政府……
1:04:43 Well, how much power do you think they have to steer humanity towards good?
那么,你认为他们有多大的力量来引导人类向善呢?
I mean, there’s a sort of age-old debate in history, like is history determined by these fundamental tides, or is it determined by the captain of the ship?
我的意思是,历史上有一种古老的争论,比如历史是由这些基本潮汐决定的,还是由船长决定的?
1:04:58 It’s both, really.
确实,两者都是。
I mean, there are tides, but it also matters who’s captain of the ship.
我的意思是,潮汐是存在的,但谁是船长也很重要。
So, it’s a false dichotomy, essentially.
所以,本质上这是一种错误的二分法。
I mean, there are certainly tides, the tides of history.
我的意思是,确实有潮汐,历史的潮汐。
There are real tides of history, and these tides are often technologically driven.
历史确实存在潮流,而这些潮流往往是由技术驱动的。
If you say like the Gutenberg press, the widespread availability of books as a result of a printing press, that was a massive tide of history, and independent of any ruler.
如果你说像古腾堡印刷机一样,由于印刷机而导致书籍的广泛使用,那是历史的巨大浪潮,并且独立于任何统治者。
But in stormy times, you want the best possible captain of the ship.
但在暴风雨时期,您需要最好的船长。
Well, first of all, thank you for recommending Will and Ariel Durant’s work.
嗯,首先,感谢您推荐威尔和阿里尔·杜兰特的作品。
1:05:54 I’ve read the short one for now, The-
我现在已经读完了短篇,The-
The Lessons of History.
历史的教训。
…
……
1:06:02 Lessons of History.
历史的教训。
Yeah.
是的。
So one of the lessons, one of the things they highlight, is the importance of technology, technological innovation, which is funny because they wrote so long ago, but they were noticing that the rate of technological innovation was speeding up.
因此,他们强调的教训之一是技术、技术创新的重要性,这很有趣,因为他们很久以前就写过,但他们注意到技术创新的速度正在加快。
Yeah, over the years.
是的,这些年来。
I would love to see what they think about now.
我很想看看他们现在怎么想。
1:06:21 But yeah, so to me, the question is how much government, how much politicians get in the way of technological innovation and building versus help it?
但是,是的,对我来说,问题是有多少政府、政客在多大程度上阻碍了技术创新和建设,而不是帮助它?
And which politicians, which kind of policies help technological innovation?
哪些政客、什么样的政策有利于技术创新?
Because that seems to be, if you look at human history, that’s an important component of empires rising and succeeding.
因为如果你回顾人类历史,这似乎是帝国崛起和成功的重要组成部分。
Yeah.
是的。
1:06:46 Well, I mean in terms of dating civilization, the start of civilization, I think the start of writing, in my view, that’s what I think is probably the right starting point to date civilization.
嗯,我的意思是就约会文明而言,文明的开始,我认为写作的开始,在我看来,这可能是约会文明的正确起点。
And from that standpoint, civilization has been around for about 5,500 years when writing was invented by the ancient Sumerians, who are gone now, but the ancient Sumerians.
从这个角度来看,文明已经存在了大约 5500 年,当时古代苏美尔人发明了文字,现在古苏美尔人已经消失了。
In terms of getting a lot of firsts, those ancient Sumerians really have a long list of firsts.
论获得很多第一,那些古代苏美尔人确实有一长串的第一。
It’s pretty wild.
这真是太疯狂了。
In fact, Durant goes through the list of like, “You want to see firsts?
事实上,杜兰特列出了这样的清单:“你想看到第一吗?
We’ll show you firsts.” The Sumerians were just ass kickers.
我们将首先向您展示。”苏美尔人只是一群混蛋。
1:07:32 And then the Egyptians, who were right next door, relatively speaking, they weren’t that far, developed an entirely different form of writing, the hieroglyphics.
然后,就在隔壁的埃及人,相对而言,他们并没有那么远,他们发展了一种完全不同的书写形式,即象形文字。
Cuneiform and hieroglyphics are totally different.
楔形文字和象形文字完全不同。
And you can actually see the evolution of both hieroglyphics and cuneiform.
你实际上可以看到象形文字和楔形文字的演变。
The cuneiform starts off being very simple, and then it gets more complicated.
楔形文字一开始非常简单,然后变得更加复杂。
Then towards the end it’s like, “Wow, okay.” They really get very sophisticated with the cuneiform.
然后到了最后,我会说:“哇,好吧。”他们对楔形文字确实非常熟练。
So, I think of civilization as being about 5, 000 years old.
所以,我认为文明已有大约五千年的历史。
And Earth is, if physics is correct, four and a half billion years old.
如果物理学是正确的,地球已有四十五亿年的历史。
So, civilization has been around for one millionth of Earth’s existence.
因此,文明已经存在了地球存在的百万分之一的时间。
Flash in the pan.
在锅里闪光。
Yeah, these are the early, early days.
是的,现在还很早期。
Very early.
很早。
And so, we make it very dramatic because there’s been rises and falls of empires and-
所以,我们让它变得非常戏剧化,因为帝国的兴衰和——
Many.
很多。
1:08:22 So many rises and falls of empires.
帝国的兴衰如此之多。
So many.
这么多。
And there’ll be many more.
还有更多。
Yeah, exactly.
是的,完全正确。
1:08:30 I mean, only a tiny fraction, probably less than 1% of what was ever written in history is available to us now.
我的意思是,我们现在能看到的只是历史上记载的一小部分,可能还不到 1%。
I mean, if they didn’t literally chisel it in stone or put it in a clay tablet, we don’t have it.
我的意思是,如果他们没有真正将其凿在石头上或将其放入粘土片中,我们就没有它。
I mean, there’s some small amount of papyrus scrolls that were recovered that are thousands of years old, because they were deep inside a pyramid and weren’t affected by moisture.
我的意思是,有一些少量的纸莎草卷轴被发现已有数千年的历史,因为它们位于金字塔深处并且不受水分的影响。
But other than that, it’s really got to be in a clay tablet or chiseled.
但除此之外,它确实必须是在泥板上或凿成的。
So, the vast majority of stuff was not chiseled because it takes a while to chisel things.
所以,绝大多数的东西都没有凿,因为凿东西需要一段时间。
So, that’s why we’ve got tiny, tiny fraction of the information from history.
所以,这就是为什么我们从历史中得到的信息非常非常少。
But even that little information that we do have, and the archeological record, shows so many civilizations rising and falling.
但即使我们掌握的信息和考古记录很少,也显示了如此多的文明的兴衰。
It’s wild.
它很狂野。
We tend to think that we’re somehow different from those people.
我们倾向于认为我们与那些人有所不同。
1:09:21 One of the other things that Durant highlights is that human nature seems to be the same.
杜兰特强调的另一件事是,人性似乎是相同的。
It just persists.
它只是持续存在。
Yeah.
是的。
1:09:31 I mean, the basics of human nature are more or less the same.
我的意思是,人性的基本原理或多或少是相同的。
Yeah.
是的。
So, we get ourselves in trouble in the same kinds of ways, I think, even with the advanced technology.
因此,我认为,即使拥有先进的技术,我们也会以同样的方式陷入困境。
Yeah.
是的。
1:09:40 I mean, you do tend to see the same patterns, similar patterns for civilizations, where they go through a life cycle, like an organism, just like a human is a zygote, fetus, baby, toddler, teenager, eventually gets old.
我的意思是,你确实倾向于看到相同的模式,文明的相似模式,它们经历一个生命周期,就像一个有机体,就像人类是受精卵、胎儿、婴儿、幼儿、青少年,最终变老。
1:10:01 …
……
Eventually gets old and dies.
最终变老并死亡。
The civilizations go through a life cycle.
文明有一个生命周期。
No civilization will last forever.
没有哪个文明能够永垂不朽。
What do you think it takes for the American Empire to not collapse in the near term future, in the next a hundred years, to continue flourishing?
您认为如何才能让美利坚帝国在不久的将来、在接下来的一百年里不崩溃,并继续繁荣?
Well, the single biggest thing that is often actually not mentioned in history books, but Durant does mention it, is the birthright.
嗯,历史书中通常没有提到的最重要的事情,但杜兰特确实提到了,那就是与生俱来的权利。
1:10:28 So perhaps to some, a counterintuitive thing happens when civilizations are winning for too long, the birth rate declines.
因此,也许对某些人来说,当文明获胜时间过长时,就会发生违反直觉的事情,出生率下降。
It can often decline quite rapidly.
它通常会迅速下降。
We’re seeing that throughout the world today.
今天我们在世界各地都看到了这一点。
Currently, South Korea is, I think maybe the lowest fertility rate, but there are many others that are close to it.
目前,我认为韩国的生育率可能是最低的,但还有许多其他国家接近它。
It’s like 0.8 I think.
我想大概是0.8。
If the birth rate doesn’t decline further, South Korea will lose roughly 60% of its population.
如果出生率不再进一步下降,韩国将失去大约60%的人口。
But every year that birth rate is dropping, and this is true through most of the world.
但出生率逐年下降,世界上大部分地区都是如此。
I don’t mean to single out South Korea, it’s been happening throughout the world.
我并不是专门针对韩国,这种情况在世界各地都在发生。
So as soon as any given civilization reaches a level of prosperity, the birth rate drops.
因此,一旦任何特定文明达到繁荣水平,出生率就会下降。
1:11:40 Now you can go and look at the same thing happening in ancient Rome.
现在你可以去看看古罗马发生的同样的事情。
So Julius Caesar took note of this, I think around 50 ish BC and tried to pass…
所以朱利叶斯·凯撒注意到了这一点,我想是在公元前 50 年左右,并试图通过……
I don’t know if he was successful, tried to pass a law to give an incentive for any Roman citizen that would have a third child.
我不知道他是否成功,试图通过一项法律来激励任何想要生第三个孩子的罗马公民。
And I think Augustus was able to…
我认为奥古斯都能够……
Well, he was a dictator, so this incentive was just for show.
好吧,他是一个独裁者,所以这个激励只是作秀。
I think he did pass a tax incentive for Roman citizens to have a third child.
我认为他确实通过了对罗马公民生第三个孩子的税收优惠。
But those efforts were unsuccessful.
但这些努力没有成功。
Rome fell because the Romans stopped making Romans.
罗马衰落是因为罗马人不再制造罗马人。
That’s actually the fundamental issue.
这实际上是根本问题。
And there were other things.
还有其他的事情。
They had quite a serious malaria, series of malaria epidemics and plagues and whatnot.
他们患有相当严重的疟疾,一系列疟疾流行病和瘟疫等等。
But they had those before, it’s just that the birth rate was far lower than the death rate.
但他们以前也有过,只是出生率远低于死亡率。
It really is that simple.
确实就是这么简单。
Well, I’m saying that’s-
嗯,我是说那是——
More people is required.
需要更多的人。
At a fundamental level, if a civilization does not at least maintain its numbers, it’ll disappear.
从根本上讲,如果一个文明不能至少维持其数量,它就会消失。
So perhaps the amount of compute that the biological computer allocates to sex is justified.
因此,生物计算机分配给性别的计算量也许是合理的。
1:12:58 In fact, we should probably increase it.
事实上,我们或许应该增加它。
Well, I mean there’s this hedonistic sex, which is…
嗯,我的意思是有这种享乐主义的性行为,那就是……
1:13:07 That’s neither her nor there.
那既不是她,也不在那里。
It’s-
这是——
Not productive.
没有生产力。
It doesn’t produce kids.
它不会产生孩子。
1:13:17 Well, what matters…
好吧,重要的是……
I mean, Durant makes this very clear because he’s looked at one civilization after another and they all went through the same cycle.
我的意思是,杜兰特说得很清楚,因为他观察了一个又一个文明,它们都经历了相同的周期。
When the civilization was under stress, the birth rate was high.
当文明面临压力时,出生率很高。
But as soon as there were no external enemies or they had an extended period of prosperity, the birth rate inevitably dropped.
但一旦没有外敌,或者长期繁荣,出生率就不可避免地下降。
Every time.
每次。
I don’t believe there’s a single exception.
我不相信有一个例外。
So that’s like the foundation of it.
这就是它的基础。
1:13:45 You need to have people.
你需要有人。
Yeah.
是的。
1:13:49 I mean, at a base level, no humans, no humanity.
我的意思是,从根本上来说,没有人类,没有人性。
And then there’s other things like human freedoms and just giving people the freedom to build stuff.
还有其他的事情,比如人类自由,以及给予人们建造东西的自由。
Yeah, absolutely.
是的,绝对是。
1:14:02 But at a basic level, if you do not at least maintain your numbers, if you’re below replacement rate and that trend continues, you will eventually disappear.
但在基本层面上,如果你不至少保持你的数字,如果你低于替代率并且这种趋势持续下去,你最终会消失。
It’s just elementary.
这只是初级的。
Now then obviously you also want to try to avoid massive wars.
现在显然你也想尽量避免大规模战争。
If there’s a global thermonuclear war, probably we’re all toast, radioactive toast.
如果爆发全球热核战争,我们可能都会完蛋,放射性烤面包。
So we want to try to avoid those things.
所以我们要尽量避免这些事情。
Then there’s a thing that happens over time with any given civilization, which is that the laws and regulations accumulate.
对于任何特定的文明来说,随着时间的推移,都会发生一件事,那就是法律和法规的积累。
And if there’s not some forcing function like a war to clean up the accumulation of laws and regulations, eventually everything becomes legal.
如果没有像战争这样的强制作用来清理法律法规的积累,最终一切都会变得合法。
1:15:02 And that’s like the hardening of the arteries.
这就像动脉硬化一样。
Or a way to think of it is being tied down by a million little strings like Gulliver.
或者一种思考方式是像格列佛一样被一百万条细绳拴住。
You can’t move.
你不能动。
And it’s not like any one of those strings is the issue, it’s that you’ve got a million of them.
问题不在于这些字符串中的任何一个,而在于你有一百万个字符串。
So there has to be a sort of garbage collection for laws and regulations so that you don’t keep accumulating laws and regulations to the point where you can’t do anything.
所以必须有一种法律法规的垃圾收集,这样你就不会不断地积累法律法规到你无能为力的地步。
This is why we can’t build a high speed rail in America.
这就是为什么我们不能在美国修建高铁。
It’s illegal.
这是非法的。
That’s the issue.
这就是问题所在。
It’s illegal six ways a Sunday to build high speed rail in America.
在美国,周日有六种方式修建高铁是违法的。
I wish you could just for a week go into Washington and be the head of the committee for making…
我希望你能去华盛顿一周,并担任委员会的负责人,以制定……
1:15:45 What is it for the garbage collection?
垃圾收集有什么用?
Making government smaller, like removing stuff.
缩小政府规模,就像删除一些东西一样。
I have discussed with Trump the idea of a government deficiency commission.
我曾与特朗普讨论过成立政府缺陷委员会的想法。
Nice.
好的。
And I would be willing to be part of that commission.
我愿意成为该委员会的一部分。
I wonder how hard that is.
我想知道这有多难。
The antibody reaction would be very strong.
抗体反应会非常强烈。
Yes.
是的。
So you really have to…
所以你真的必须……
1:16:14 You’re attacking the matrix at that point.
那时你正在攻击矩阵。
The matrix will fight back.
矩阵将会反击。
How are you doing with that?
你怎么样?
1:16:26 Being attacked.
受到攻击。
Me?
我?
1:16:29 Attacked?
受到攻击?
Yeah, there’s a lot of it.
是的,有很多。
Yeah, there is a lot.
是的,有很多。
1:16:34 I mean, every day another psyop.
我的意思是,每天都有一次心理检查。
I need my tinfoil hat.
我需要我的锡纸帽子。
How do you keep your just positivity?
你如何保持公正的积极性?
1:16:42 How do you keep optimism about the world?
如何对世界保持乐观态度?
A clarity of thinking about the world.
对世界的清晰思考。
So just not become resentful or cynical or all that kind of stuff.
所以不要变得怨恨或愤世嫉俗或诸如此类的事情。
Just getting attacked by a very large number of people, misrepresented.
只是受到了很多人的攻击,被歪曲了。
Oh yeah, that’s a daily occurrence.
哦,是的,这是每天都会发生的事情。
Yes.
是的。
So I mean, it does get me down at times.
所以我的意思是,它有时确实让我沮丧。
1:16:59 I mean, it makes me sad.
我的意思是,这让我很难过。
But I mean at some point you have to sort of say, look, the attacks are by people that actually don’t know me and they’re trying to generate clicks.
但我的意思是,在某些时候你必须说,看,这些攻击是由实际上不认识我的人发起的,他们试图产生点击量。
So if you can sort of detach yourself somewhat emotionally, which is not easy, and say, okay look, this is not actually from someone that knows me or, they’re literally just writing to get impressions and clicks.
因此,如果你能在情感上脱离自己,这并不容易,然后说,好吧,这实际上不是来自认识我的人,或者,他们实际上只是为了获得印象和点击而写作。
Then I guess it doesn’t hurt as much.
然后我想它就不会那么痛了。
It’s not quite water off a duck’s back.
这不完全是鸭子背上的水。
Maybe it’s like acid off a duck’s back.
也许就像鸭子背上的酸一样。
All right, well that’s good.
好吧,那就好。
1:17:53 Just about your own life, what to you is a measure of success in your life?
就你自己的生活而言,对你来说衡量你生活成功的标准是什么?
A measure of success, I’d say, how many useful things can I get done?
我想说,衡量成功的标准是,我能完成多少有用的事情?
A day-to-day basis, you wake up in the morning, how can I be useful today?
日复一日,你早上醒来,我今天能有什么用处呢?
Yeah, maximize utility, area under the code of usefulness.
是的,最大化实用性,实用性代码下的区域。
1:18:09 Very difficult to be useful at scale.
很难大规模发挥作用。
At scale.
规模化。
1:18:17 Can you speak to what it takes to be useful for somebody like you, where there’s so many amazing great teams?
您能否谈谈如何才能对像您这样的人有用,因为那里有这么多令人惊叹的伟大团队?
How do you allocate your time to being the most useful?
你如何分配你的时间,让自己成为最有用的人?
Well, time is the true currency.
好吧,时间才是真正的货币。
Yeah.
是的。
So it is tough to say what is the best allocation time?
那么很难说什么是最佳分配时间呢?
1:18:32 I mean, there are often…
我的意思是,经常有……
Say if you look at say Tesla, Tesla this year will do over a hundred billion in revenue.
比如说,如果你看看特斯拉,特斯拉今年的收入将超过千亿。
So that’s $2 billion a week.
也就是说每周 20 亿美元。
If I make slightly better decisions, I can affect the outcome by a billion dollars.
如果我做出稍微更好的决定,我可以对结果产生十亿美元的影响。
So then I try to do the best decisions I can.
所以我会尽力做出最好的决定。
And on balance, at least compared to the competition, pretty good decisions.
总的来说,至少与竞争对手相比,这是相当不错的决定。
But the marginal value of a better decision can easily be, in the course of an hour, a hundred million dollars.
但一个更好的决策的边际价值很容易在一小时内达到一亿美元。
Given that, how do you take risks?
鉴于此,您如何承担风险?
1:19:18 How do you do the algorithm that you mentioned?
你提到的算法是如何实现的?
I mean deleting, given that a small thing can be a billion dollars, how do you decide to-
我的意思是删除,考虑到一件小事可能价值十亿美元,你如何决定-
Yeah.
是的。
1:19:29 Well, I think you have to look at it on a percentage basis because if you look at it in absolute terms, it’s just…
好吧,我认为你必须以百分比的形式来看待它,因为如果你以绝对的方式来看待它,那就是……
I would never get any sleep.
我永远无法入睡。
It would just be like, I need to just keep working and work my brain harder.
就像,我需要继续工作,更加努力地工作我的大脑。
And I’m not trying to get as much as possible out of this meat computer.
我并不是想从这台肉类计算机中获得尽可能多的东西。
So it’s not…
所以这不是……
It’s pretty hard, because you can just work all the time.
这很难,因为你可以一直工作。
And at any given point, like I said, a slightly better decision could be a hundred million dollars impact for Tesla or SpaceX for that matter.
正如我所说,在任何特定时刻,稍微更好的决定可能是为特斯拉或 SpaceX 带来一亿美元的影响。
But it is wild when considering the marginal value of time can be a hundred million dollars an hour at times, or more.
但考虑到时间的边际价值有时可能达到每小时一亿美元,甚至更多,这就有点疯狂了。
Is your own happiness part of that equation of success?
你自己的幸福是成功方程式的一部分吗?
It has to be to some degree.
它必须在某种程度上。
1:20:22 If I’m sad, if I’m depressed, I make worse decisions.
如果我悲伤、沮丧,我就会做出更糟糕的决定。
So if I have zero recreational time, then I make worse decisions.
因此,如果我的娱乐时间为零,那么我会做出更糟糕的决定。
So I don’t know a lot, but it’s above zero.
所以我知道的不多,但它大于零。
I mean, my motivation if I’ve got a religion of any kind is a religion of curiosity, of trying to understand.
我的意思是,如果我有任何一种宗教,我的动机就是好奇心、试图理解的宗教。
It’s really the mission of Grok, understand the universe.
理解宇宙确实是 Grok 的使命。
I’m trying to understand the universe, or at least set things in motion such that at some point civilization understands the universe far better than we do today.
我试图理解宇宙,或者至少让事物运转起来,以便在某个时候文明比我们今天更好地理解宇宙。
1:21:02 And even what questions to ask.
甚至要问什么问题。
As Douglas Adams pointed out in his book, sometimes the answer is arguably the easy part, trying to frame the question correctly is the hard part.
正如道格拉斯·亚当斯在他的书中指出的那样,有时答案可以说是容易的部分,而试图正确地提出问题才是困难的部分。
Once you frame the question correctly, the answer is often easy.
一旦你正确地提出了问题,答案通常很容易。
So I’m trying to set things in motion such that we are at least at some point able to understand the universe.
所以我试图让事物运转起来,这样我们至少在某个时刻能够理解宇宙。
So for SpaceX, the goal is to make life multi planetary and which is if you go to the foamy paradox of where the aliens, you’ve got these sort of great filters.
因此,对于 SpaceX 来说,目标是让生命在多行星上存在,如果你去了解外星人所在的泡沫悖论,你就会得到这些很棒的过滤器。
Like why have we not heard from the aliens?
比如为什么我们没有收到外星人的消息?
Now a lot of people think there are aliens among us.
现在很多人认为我们中间有外星人。
I often claim to be one, which nobody believes me.
我经常声称自己是其中之一,但没有人相信我。
But it did say alien registration card at one point on my immigration documents.
但我的移民文件上确实曾经提到过外国人登记卡。
So I’ve not seen any evidence of aliens.
所以我没有看到任何外星人存在的证据。
So it suggests that at least one of the explanations is that intelligent life is extremely rare.
因此,这表明至少一种解释是智慧生命极其罕见。
1:22:19 And again, if you look at the history of earth, civilization has only been around for 1000000th of earth’s existence.
再说一次,如果你回顾一下地球的历史,就会发现文明只存在了地球存在的千万分之一的时间。
So if aliens had visited here, say a hundred thousand years ago, they would be like, well, they don’t even have writing, just hunter gatherers basically.
因此,如果外星人在十万年前访问过这里,他们会说,好吧,他们甚至没有文字,基本上只是狩猎采集者。
So how long does a civilization last?
那么一个文明能持续多久呢?
So for SpaceX, the goal is to establish a self-sustaining city on Mars.
所以对于SpaceX来说,目标是在火星上建立一座自给自足的城市。
Mars is the only viable planet for such a thing.
火星是唯一可行的行星。
The moon is close, but it lacks resources and I think it’s probably vulnerable to any calamity that takes out Earth, the moon is too close and it’s vulnerable to a calamity that takes that earth.
月球很近,但它缺乏资源,我认为它可能很容易受到任何毁灭地球的灾难的影响,月球太近了,它很容易受到毁灭地球的灾难的影响。
1:23:16 So I’m not saying we shouldn’t have a moon base, but Mars would be far more resilient.
所以我并不是说我们不应该建立月球基地,但火星的适应能力要强得多。
The difficulty of getting to Mars is what makes it resilient.
到达火星的困难使其具有弹性。
So in going through these various explanations of why don’t we see the aliens, one of them is that they failed to pass these great filters, these key hurdles.
因此,在对为什么我们看不到外星人的各种解释中,其中之一是他们未能通过这些伟大的过滤器,这些关键障碍。
And one of those hurdles is being a multi-planet species.
这些障碍之一是成为多行星物种。
So if you’re a multi-planet species, then if something were to happen, whether that was a natural catastrophe or a manmade catastrophe, at least the other planet would probably still be around.
因此,如果你是一个多行星物种,那么如果发生什么事情,无论是自然灾难还是人为灾难,至少另一个行星可能仍然存在。
So you’re not like, don’t have all the eggs in one basket.
所以你不会把所有的鸡蛋都放在一个篮子里。
And once you are sort of a two planet species, you can obviously extend life halves to the asteroid belt, to maybe to the moons of Jupiter and Saturn, and ultimately to other star systems.
一旦你成为了两颗行星的物种,你显然可以将生命的一半延伸到小行星带,也许延伸到木星和土星的卫星,并最终延伸到其他恒星系统。
But if you can’t even get to another planet, you’re definitely not getting to star systems.
但如果你连另一个星球都无法到达,那你肯定就无法到达恒星系统。
And the other possible great filter’s, super powerful technology like AGI for example.
还有另一种可能的伟大过滤器,超级强大的技术,例如 AGI。
1:24:30 So you are basically trying to knock out one great filter at a time.
所以你基本上是在尝试一次淘汰一个很棒的过滤器。
Digital super intelligence is possibly a great filter.
数字超级智能可能是一个很好的过滤器。
1:24:44 I hope it isn’t, but it might be.
我希望不是,但也可能是。
Guys like say Jeff Hinton would say, he invented a number of the key principles in artificial intelligence.
像 Jeff Hinton 这样的人会说,他发明了人工智能的许多关键原理。
I think he puts the probability of AI annihilation around 10% to 20%, something like that.
我认为他认为人工智能毁灭的概率约为 10% 到 20%,类似的数字。
So look on the bright side, it’s 80% likely to be great.
所以从好的方面来看,80% 的可能性都是好的。
But I think AI risk mitigation is important.
但我认为缓解人工智能风险很重要。
Being a multi-planet species would be a massive risk mitigation.
成为多行星物种将是一个巨大的风险缓解。
And I do want to once again emphasize the importance of having enough children to sustain our numbers, and not plummet into population collapse, which is currently happening.
我确实想再次强调拥有足够的孩子来维持我们的人口数量的重要性,而不是陷入目前正在发生的人口崩溃。
Population collapse is a real and current thing.
人口崩溃是一个真实的、当前的事情。
1:25:51 So the only reason it’s not being reflected in the total population numbers as much is because people are living longer.
因此,它没有在总人口中反映出来的唯一原因是人们的寿命更长。
But it’s easy to predict, say what the population of any given country will be.
但预测任何特定国家的人口数量是很容易的。
Just take the birth rate last year, how many babies were born, multiply that by life expectancy and that’s what the population will be, steady state, if the birth rate continues to that level.
只需计算去年的出生率,即出生的婴儿数量,乘以预期寿命,这就是如果出生率继续保持在这一水平的话,稳定状态下的人口数量。
But if it keeps declining, it will be even less and eventually dwindle to nothing.
但如果继续下降,就会更少,最终化为乌有。
So I keep banging on the baby drum here, for a reason, because it has been the source of civilizational collapse over and over again throughout history.
所以我一直在这里敲小鼓,这是有原因的,因为它在历史上一次又一次地成为文明崩溃的根源。
And so why don’t we just not try to stave off that day?
那么我们为什么不尝试推迟这一天的到来呢?
Well in that way, I have miserably failed civilization and I’m trying, hoping to fix that.
就这样,我的文明彻底失败了,我正在努力,希望能够解决这个问题。
1:26:41 I would love to have many kids.
我很想有很多孩子。
Great.
伟大的。
1:26:49 Hope you do.
希望你能做到。
No time like the present.
没有比现在更好的时间了。
Yeah, I got to allocate more compute to the whole process, but apparently it’s not that difficult.
是的,我必须为整个过程分配更多的计算,但显然这并不那么困难。
No, it’s like unskilled labor.
不,这就像非熟练劳动力。
Well, one of the things you do for me, for the world, is to inspire us with what the future could be.
嗯,你为我、为世界所做的事情之一,就是激励我们了解未来。
1:27:06 And so some of the things we’ve talked about, some of the things you’re building, alleviating human suffering with Neuralink and expanding the capabilities of the human mind, trying to build a colony on Mars.
因此,我们讨论过的一些事情,你们正在建造的一些事情,通过 Neuralink 减轻人类痛苦并扩展人类思维的能力,试图在火星上建立一个殖民地。
So creating a backup for humanity on another planet and exploring the possibilities of what artificial intelligence could be in this world, especially in the real world, AI with hundreds of millions, maybe billions of robots walking around.
因此,在另一个星球上为人类创建一个备份,并探索人工智能在这个世界上的可能性,特别是在现实世界中,人工智能有数亿甚至数十亿机器人在周围行走。
There will be billions of robots.
将会有数十亿个机器人。
1:27:45 That seems virtual certainty.
这似乎是板上钉钉的事情。
Well, thank you for building the future and thank you for inspiring so many of us to keep building and creating cool stuff, including kids.
好吧,感谢您建设未来,感谢您激励我们很多人继续建设和创造很酷的东西,包括孩子们。
You’re welcome.
不客气。
1:28:00 Go forth and multiply.
继续前进并繁衍。
Go forth, multiply.
前进,繁衍。
1:28:04 Thank you Elon.
谢谢埃隆。
Thanks for talking about it.
谢谢你谈论它。
Thanks for listening to this conversation with Elon Musk.
感谢您收听与埃隆·马斯克的对话。
And now, dear friends, here’s DJ Seo, the Co-Founder, President and COO of Neuralink.
现在,亲爱的朋友们,这是 Neuralink 联合创始人、总裁兼首席运营官 DJ Seo。
When did you first become fascinated by the human brain?
您什么时候第一次对人脑着迷?
For me, I was always interested in understanding the purpose of things and how it was engineered to serve that purpose, whether it’s organic or inorganic, like we were talking earlier about your curtain holders.
对我来说,我总是对理解事物的目的以及它是如何设计来服务于该目的感兴趣,无论是有机的还是无机的,就像我们之前讨论的窗帘架一样。
1:28:23 They serve a clear purpose and they were engineered with that purpose in mind.
它们有明确的目的,并且在设计时就考虑到了这一目的。
And growing up I had a lot of interest in seeing things, touching things, feeling things, and trying to really understand the root of how it was designed to serve that purpose.
在成长过程中,我对观察事物、触摸事物、感受事物非常感兴趣,并试图真正理解它是如何设计来实现这一目的的根源。
And obviously brain is just a fascinating organ that we all carry.
显然,大脑是我们所有人都拥有的一个令人着迷的器官。
It’s an infinitely powerful machine that has intelligence and cognition that arise from it.
它是一台无限强大的机器,具有由此产生的智能和认知。
And we haven’t even scratched the surface in terms of how all of that occurs.
对于这一切是如何发生的,我们甚至还没有触及表面。
1:29:17 But also at the same time, I think it took me a while to make that connection to really studying and building tech to understand the brain.
但与此同时,我认为我花了一段时间才将这种联系与真正研究和构建理解大脑的技术联系起来。
Not until graduate school.
直到研究生毕业。
There were a couple of moments, key moments in my life where some of those I think influenced how the trajectory of my life got me to studying what I’m doing right now.
在我生命中的一些时刻,一些关键时刻,我认为其中一些影响了我的生活轨迹,让我开始研究我现在正在做的事情。
One was growing up, both sides of my family, my grandparents had a very severe form of Alzheimer and it’s incredibly debilitating conditions.
一个是在我的成长过程中,我的家人、我的祖父母都患有一种非常严重的阿尔茨海默病,这是一种令人难以置信的衰弱状况。
I mean, literally you’re seeing someone’s whole identity and their mind just losing over time.
我的意思是,从字面上看,你会看到某人的整个身份和他们的思想随着时间的推移而消失。
And I just remember thinking how both the power of the mind, but also how something like that could really lose your sense of identity.
我只记得我在想,心灵的力量,以及类似的东西如何真的会失去你的认同感。
It’s fascinating that that is one of the ways to reveal the power of a thing by watching it lose the power.
令人着迷的是,这是通过观察事物失去力量来揭示其力量的方法之一。
Yeah, a lot of what we know about the brain actually comes from these cases where there are trauma to the brain or some parts of the brain that led someone to lose certain abilities.
是的,我们对大脑的了解实际上来自这些案例,即大脑或大脑某些部分受到创伤,导致某人失去某些能力。
1:30:17 And as a result there’s some correlation and understanding of that part of the tissue being critical for that function.
因此,对于该功能至关重要的组织部分存在一些相关性和理解。
And it’s an incredibly fragile organ, if you think about it that way.
如果你这样想的话,它是一个极其脆弱的器官。
But also it’s incredibly plastic and incredibly resilient in many different ways.
而且它在许多方面都具有令人难以置信的塑料性和令人难以置信的弹性。
And by the way, the term plastic as we’ll use a bunch, means that it’s adaptable.
顺便说一下,我们会经常使用“塑料”这个术语,意思是它具有适应性。
1:30:46 So neuroplasticity refers to the adaptability of the human brain?
那么神经可塑性是指人脑的适应性吗?
Correct.
正确的。
1:30:56 Another key moment that sort of influenced how the trajectory of my life have shaped towards the current focus of my life has been during my teenage year when I came to the US.
另一个影响我的人生轨迹如何塑造我当前生活焦点的关键时刻是我十几岁的时候,当时我来到了美国。
I didn’t speak a word of English.
我一句英语也没说。
There was a huge language barrier and there was a lot of struggle to connect with my peers around me because I didn’t understand the artificial construct that we have created called language, specifically English in this case.
存在巨大的语言障碍,与周围的同龄人联系有很多困难,因为我不理解我们创建的称为语言的人工结构,特别是在这种情况下的英语。
And I remember feeling pretty isolated, not being able to connect with peers around me.
我记得我感到非常孤立,无法与周围的同龄人联系。
So spent a lot of time just on my own reading books, watching movies, and I naturally sort of gravitated towards sci-fi books.
所以我花了很多时间看书、看电影,我自然而然地被科幻小说所吸引。
I just found them really, really interesting.
我发现它们真的非常非常有趣。
And also it was a great way for me to learn English.
这对我来说也是学习英语的好方法。
1:31:46 Some of the first set of books that I picked up are Enders Game, the whole saga by Orson Scott Card and Neuromancer from William Gibson and Snow Crash from Neal Stephenson.
我买的第一套书是《Enders Game》,奥森·斯科特·卡德的整个传奇故事,威廉·吉布森的《神经漫游者》和尼尔·斯蒂芬森的《雪崩》。
And movies like Matrix, what’s coming out around that time point that really influenced how I think about the potential impact that technology can have for our lives in general.
像《黑客帝国》这样的电影,在那个时间点上映的电影真正影响了我对技术对我们生活的潜在影响的看法。
1:32:11 So fast track to my college years, I was always fascinated by just physical stuff, building physical stuff and especially physical things that had some sort of intelligence.
进入大学时代后,我总是着迷于物理事物、建造物理事物,尤其是具有某种智能的物理事物。
And I studied electrical engineering during undergrad and I started out my research in MEMS, so micro electromechanical systems and really building these tiny nano structures for temperature sensing.
我在本科期间学习了电气工程,并开始了 MEMS、微机电系统的研究,并真正构建了这些用于温度传感的微小纳米结构。
And I just found that to be just incredibly rewarding and fascinating subject to just understand how you can build something miniature like that, that again, serve a function and had a purpose.
我发现这是一个令人难以置信的回报和令人着迷的主题,只是了解如何构建这样的微型东西,再次,服务于功能并有一个目的。
Then I spent large majority of my college years basically building millimeter wave circuits for next gen telecommunication systems for imaging.
然后,我大学的大部分时间都花在为下一代成像电信系统构建毫米波电路上。
And it was just something that I found very, very intellectually interesting.
我发现这在智力上非常非常有趣。
Phase arrays, how the signal processing works for any modern as well as next gen telecommunication system, wireless and wire line, EM waves or electromagnetic waves are fascinating.
相控阵、信号处理如何适用于任何现代以及下一代电信系统、无线和有线、EM 波或电磁波都是令人着迷的。
1:33:17 How do you design antennas that are most efficient in a small footprint that you have?
如何在较小的占地面积内设计最高效的天线?
How do you make these things energy efficient?
如何使这些东西变得节能?
That was something that just consumed my intellectual curiosity and that journey led me to actually apply to and find myself at PhD program at UC Berkeley, at this consortium called the Berkeley Wireless Research Center that was precisely looking at building…
这消耗了我的求知欲,这段旅程让我真正申请并找到了自己在加州大学伯克利分校的博士项目,在这个名为伯克利无线研究中心的联盟中,该联盟正是致力于建立……
At the time, we called it XG, similar to 3G, 4G, 5G, but the next, next generation G system and how you would design circuits around that to ultimately go on phones and basically any other devices that are wirelessly connected these days.
当时,我们称之为 XG,类似于 3G、4G、5G,但它是下一代 G 系统,以及如何围绕该系统设计电路,最终应用在手机和基本上任何其他当今无线连接的设备上。
So I was just absolutely just fascinated by how that entire system works and that infrastructure works.
所以我对整个系统的工作原理和基础设施的工作原理非常着迷。
1:34:07 And then also during grad school, I had sort of the fortune of having a couple of research fellowships that led me to pursue whatever project that I want.
然后,在读研究生期间,我有幸获得了一些研究奖学金,这使我能够追求任何我想要的项目。
And that’s one of the things that I really enjoyed about my graduate school career, where you got to kind of pursue your intellectual curiosity in the domain that may not matter at the end of the day, but is something that really allows you the opportunity to go as deeply as you want, as well as widely as you want.
这是我在研究生生涯中真正喜欢的事情之一,在那里你必须在某个领域追求你的求知欲,虽然最终可能并不重要,但它确实让你有机会按照你想要的方式深入、广泛地探索。
And at the time I was actually working on this project called the Smart Bandaid, and the idea was that when you get a wound, there’s a lot of other proliferation of signaling pathway that cells follow to close that wound.
当时我实际上正在研究一个名为“智能创可贴”的项目,其想法是,当你受伤时,细胞会遵循许多其他信号通路的增殖来闭合伤口。
And there were hypotheses that when you apply external electric field, you can actually accelerate the closing of that field by having basically electro taxing of the cells around that wound site.
有人假设,当你施加外部电场时,你实际上可以通过对伤口部位周围的细胞进行基本的电刺激来加速该电场的关闭。
1:35:06 And specifically not just for a normal wound, there are chronic wounds that don’t heal.
特别是不仅对于正常伤口,还有无法愈合的慢性伤口。
So we were interested in building some sort of a wearable patch that you could apply to facilitate that healing process.
因此,我们有兴趣构建某种可穿戴贴片,您可以使用它来促进愈合过程。
And that was in collaboration with Professor Michel Maharbiz, which was a great addition to my thesis committee and it really shaped the rest of my PhD career.
那是与米歇尔·马哈比兹教授合作的,他对我的论文委员会来说是一个很好的补充,它确实塑造了我余下的博士生涯。
So this would be the first time you interacted with biology, I suppose?
所以我想这将是你第一次与生物学互动?
Correct.
正确的。
1:35:37 I mean there were some peripheral end application of the wireless imaging and telecommunication system that I was using for security and bio imaging.
我的意思是,我用于安全和生物成像的无线成像和电信系统有一些外围终端应用。
But this was a very clear direct application to biology and biological system and understanding the constraints around that and really designing and engineering electrical solutions around that.
但这是对生物学和生物系统的非常明确的直接应用,了解其周围的限制,并真正围绕其设计和工程电气解决方案。
So that was my first introduction and that’s also kind of how I got introduced to Michel.
这是我的第一次介绍,也是我认识米歇尔的方式。
He’s sort of known for remote control of beetles in the early two thousands.
他因远程控制两千出头的甲虫而闻名。
1:36:16 And then around 2013, obviously the holy grail when it comes to implantable system is to understand how small of a thing you can make, and a lot of that is driven by how much energy or how much power you can supply to it and how you extract data from it.
然后在 2013 年左右,显然,植入式系统的圣杯是了解你可以制造出多小的东西,而这很大程度上取决于你可以向它提供多少能量或多少功率以及如何从中提取数据。
At the time at Berkeley, there was this desire to understand in the neural space what sort of system you can build to really miniaturize these implantable systems.
当时在伯克利,人们希望了解在神经空间中可以构建什么样的系统来真正小型化这些可植入系统。
And I distinctively remember this one particular meeting where Michel came in and he’s like, “Guys, I think I have a solution.
我清楚地记得在一次特殊的会议上,米歇尔进来了,他说:“伙计们,我想我有一个解决方案。
The solution is ultrasound.” And then he proceeded to walk through why that is the case.
解决方案是超声波。”然后他继续解释为什么会出现这种情况。
And that really formed the basis for my thesis work called Neural dust system, that was looking at ways to use ultrasound as opposed to electromagnetic waves for powering as well as communication.
这确实构成了我名为“神经尘埃系统”的论文工作的基础,该论文正在研究使用超声波而不是电磁波来供电和通信的方法。
I guess I should step back and say the initial goal of the project was to build these tiny, about a size of a neuron, implantable system that can be parked next to a neuron, being able to record its state and being able to ping that back to the outside world for doing something useful.
我想我应该退后一步说,该项目的最初目标是构建这些微小的、大约神经元大小的可植入系统,可以停在神经元旁边,能够记录其状态,并能够将其返回给外界以做一些有用的事情。
And as I mentioned, the size of the implantable system is limited by how you power the thing and get the data off of it.
正如我所提到的,植入式系统的大小受到其供电方式和从中获取数据的方式的限制。
And at the end of the day, fundamentally, if you look at a human body, we’re essentially bag of salt water with some interesting proteins and chemicals, but its mostly salt water that’s very, very well temperature regulated at 37 degrees Celsius.
归根结底,如果你观察人体,我们本质上就是一袋盐水,里面含有一些有趣的蛋白质和化学物质,但其中大部分是盐水,温度非常非常好地控制在 37 摄氏度。
1:38:05 And we’ll get into how, and later why that’s an extremely harsh environment for any electronics to survive.
我们将探讨如何以及为什么对于任何电子产品来说,这是一个极其恶劣的环境。
As I’m sure you’ve experienced or maybe not experienced, dropping cell phone in a salt water in an ocean, it will instantly kill the device.
我确信您经历过或可能没有经历过,将手机掉入海洋的盐水中,设备会立即损坏。
But anyways, just in general, electromagnetic waves don’t penetrate through this environment well and just the speed of light, it is what it is, we can’t change it.
但无论如何,一般来说,电磁波不能很好地穿透这个环境,光速就是这样,我们无法改变它。
And based on the wavelength at which you are interfacing with the device, the device just needs to be big.
根据与设备连接的波长,设备只需要很大即可。
These inductors needs to be quite big.
这些电感器需要相当大。
And the general good rule of thumb is that you want the wavefront to be roughly on the order of the size of the thing that you’re interfacing with.
一般好的经验法则是,您希望波前大致与您所连接的物体的尺寸相同。
So an implantable system that is around 10 to a hundred micron in dimension in a volume, which is about the size of a neuron that you see in a human body, you would have to operate at hundreds of gigahertz.
因此,一个体积约为 10 至 100 微米的可植入系统(大约相当于人体神经元的大小)必须在数百千兆赫的频率下运行。
Which number one, not only is it difficult to build electronics operating at those frequencies, but also the body just attenuates to that very, very significantly.
第一,不仅很难构建在这些频率下运行的电子设备,而且身体也会非常非常显着地衰减。
1:39:23 So the interesting kind of insight of this ultrasound was the fact that ultrasound just travels a lot more effectively in the human body tissue compared to electromagnetic waves.
因此,这种超声波的有趣之处在于,与电磁波相比,超声波在人体组织中传播的效率要高得多。
And this is something that you encounter, and I’m sure most people have encountered in their lives when you go to hospitals that are medical ultrasound sonograph.
这是你会遇到的事情,我相信大多数人一生中都遇到过,当你去有医用超声检查的医院时。
And they go into very, very deep depth without attenuating too much, too much of the signal.
它们进入非常非常深的深度,而不会衰减太多太多的信号。
So all in all, ultrasound, the fact that it travels through the body extremely well and the mechanism to which it travels to the body really well is that just the wavefront is very different.
总而言之,超声波在人体中传播得非常好,而且它传播到身体的机制非常好,只是波前非常不同。
Electromagnetic waves are transverse, whereas in ultrasound waves are compressive.
电磁波是横向的,而超声波是压缩的。
It’s just a completely different mode of wavefront propagation.
这只是一种完全不同的波前传播模式。
And as well as, speed of sound is orders and orders of magnitude less than speed of light, which means that even at 10 megahertz ultrasound wave, your wavefront ultimately is a very, very small wavelength.
而且,声速比光速低几个数量级,这意味着即使在 10 兆赫兹的超声波下,波前最终也是一个非常非常小的波长。
1:40:37 So if you’re talking about interfacing with the 10 micron or a hundred micron type structure, you would have 150 micron wavefront at 10 megahertz.
因此,如果您谈论的是与 10 微米或 100 微米类型结构的接口,那么您将在 10 兆赫兹下拥有 150 微米波前。
And building electronics at those frequencies are much, much easier and they’re a lot more efficient.
在这些频率下构建电子设备要容易得多,而且效率也高得多。
So the basic idea was born out of using ultrasound as a mechanism for powering the device and then also getting data back.
因此,基本想法诞生于使用超声波作为设备供电并获取数据的机制。
So now the question is how do you get the data back?
那么现在的问题是如何取回数据?
The mechanism to which we landed on is what’s called backscattering.
我们发现的机制就是所谓的反向散射。
This is actually something that is very common and that we interface on a day-to-day basis with our RFID cards, radio frequency ID tags.
这实际上是很常见的事情,我们每天都会与 RFID 卡、射频 ID 标签进行交互。
Where there’s actually rarely in your ID a battery inside, there’s an antenna and there’s some sort of coil that has your serial identification ID, and then there’s an external device called the reader that then sends a wavefront and then you reflect back that wavefront with some sort of modulation that’s unique to your ID.
实际上,您的身份证件中很少有电池,但有一个天线和某种带有您的序列识别 ID 的线圈,然后有一个称为读取器的外部设备,它会发送一个波前,然后您使用您的身份证件特有的某种调制反射回该波前。
That’s what’s called backscattering fundamentally.
从根本上来说,这就是所谓的后向散射。
1:41:50 So the tag itself actually doesn’t have to consume that much energy.
所以标签本身实际上不需要消耗那么多能量。
That was the mechanism through which we were thinking about sending the data back.
这就是我们考虑发回数据的机制。
When you have an external ultrasonic transducer that’s sending ultrasonic wave to your implant, the neural dust implant, and it records some information about its environment, whether it’s a neuron firing or some other state of the tissue that it’s interfacing with.
当您有一个外部超声波换能器向您的植入物(神经尘埃植入物)发送超声波时,它会记录有关其环境的一些信息,无论是神经元放电还是与之接触的组织的其他状态。
And then it just amplitude modulates the wavefront that comes back to the source.
然后它只是对返回源的波前进行幅度调制。
And the recording step would be the only one that requires any energy.
记录步骤将是唯一需要能量的步骤。
1:42:27 So what would require energy in that low step?
那么在这么低的步骤中需要什么能量呢?
Correct.
正确的。
1:42:33 So it is that initial startup circuitry to get that recording, amplifying it, and then just modulating.
因此,最初的启动电路用于获取录音、放大录音,然后进行调制。
And the mechanism to which that you can enable that is there is this specialized crystal called piezoelectric crystals that are able to convert sound energy into electrical energy and vice versa.
实现这一点的机制是一种称为压电晶体的特殊晶体,它能够将声能转换为电能,反之亦然。
So you can kind of have this interplay between the ultrasonic domain and electrical domain that is the biological tissue.
因此,超声波域和生物组织的电域之间可以产生这种相互作用。
So on the theme of parking very small computational devices next to neurons, that’s the dream, the vision of brain computer interfaces.
因此,关于将非常小的计算设备放置在神经元旁边的主题,这就是脑机接口的梦想和愿景。
1:43:04 Maybe before we talk about Neuralink, can you give a sense of the history of the field of BCI?
也许在我们谈论 Neuralink 之前,您能先介绍一下 BCI 领域的历史吗?
What has been maybe the continued dream and also some of the milestones along the way of the different approaches and the amazing work done at the various labs?
也许持续的梦想是什么,以及不同方法和各个实验室所做的令人惊叹的工作过程中的一些里程碑?
I think a good starting point is going back to 1790s.
我认为一个好的起点是 1790 年代。
I did not expect that.
我没想到会这样。
Where the concept of animal electricity or the fact that body’s electric was first discovered by Luigi Galvani, where he had this famous experiment where he connected set of electrodes to a frog leg and ran current through it, and then it started twitching and he said, “Oh my goodness, body’s electric.” So fast forward many, many years to 1920s where Hans Berger, who’s a German psychiatrist, discovered EEG or electroencephalography, which is still around.
动物电的概念或身体电的事实是由路易吉·加尔瓦尼(Luigi Galvani)首先发现的,他做了一个著名的实验,他将一组电极连接到青蛙腿上,并通过它流过电流,然后青蛙开始抽搐,他说:“哦,天哪,身体带电了。”时间快进很多很多年,到了 1920 年代,德国精神病学家汉斯·伯杰 (Hans Berger) 发现了脑电图 (EEG) 或脑电图描记术,这种技术至今仍然存在。
1:43:41 There are these electrode arrays that you wear outside the skull that gives you some sort of neural recording.
您将这些电极阵列戴在颅骨外,为您提供某种神经记录。
That was a very, very big milestone that you can record some sort of activities about the human mind.
这是一个非常非常大的里程碑,你可以记录一些关于人类思维的活动。
And then in the 1940s there were these group of scientists, Renshaw, Forbes and Morison that inserted these glass micro electrodes into the cortex and recorded single neurons.
然后在 20 世纪 40 年代,Renshaw、Forbes 和 Morison 等科学家小组将这些玻璃微电极插入皮层并记录单个神经元。
The fact that there’s signal that are a bit more high resolution and high fidelity as you get closer to the source, let’s say.
事实上,当您靠近信号源时,信号的分辨率和保真度会更高一些。
And in the 1950s, these two scientists, Hodgkin and Huxley showed up-
在 20 世纪 50 年代,霍奇金和赫胥黎这两位科学家出现了——
1:45:00 These two scientists, Hodgkin and Huxley showed up and they built this beautiful, beautiful models of the cell membrane and the ionic mechanism, and had these circuit diagram.
霍奇金和赫胥黎这两位科学家出现了,他们建立了这个非常漂亮的细胞膜和离子机制模型,并有这些电路图。
And as someone who’s an electrical engineer, it’s a beautiful model that’s built out of these partial differential equations, talking about flow of ions and how that really leads to how neurons communicate.
作为一名电气工程师,这是一个由这些偏微分方程构建的美丽模型,讨论离子流以及它如何真正导致神经元如何通信。
And they won the Nobel Prize for that 10 years later in the 1960s.
10 年后的 20 世纪 60 年代,他们因此获得了诺贝尔奖。
1:45:29 So in 1969, Eb Fetz from University of Washington published this beautiful paper called Operant Conditioning of Cortical Unit Activity, where he was able to record a single unit neuron from a monkey and was able to have the monkey modulated based on its activity and reward system.
因此,1969 年,华盛顿大学的 Eb Fetz 发表了这篇名为《皮质单元活动的操作调节》的精彩论文,其中他能够记录猴子的单个单元神经元,并能够根据猴子的活动和奖励系统来调节猴子。
So I would say this is the very, very first example, as far as I’m aware, of close loop brain computer interface or BCI.
所以我想说,据我所知,这是闭环脑机接口(BCI)的第一个例子。
The abstract reads, “The activity of single neurons in precentral cortex of unanesthetized monkeys was conditioned by reinforcing high rates of neuronal discharge with delivery of a food pellet.
摘要中写道:“未麻醉猴子中央前皮层中单个神经元的活动是通过食物颗粒的输送来增强神经元放电率来调节的。
1:46:01 Auditory or visual feedback of unit firing rates was usually provided in addition to food reinforcement.” Cool.
除了食物强化之外,通常还会提供单位射击速度的听觉或视觉反馈。”凉爽的。
So they actually got it done.
所以他们实际上做到了。
They got it done.
他们完成了。
1:46:24 This is back in 1969.
这要追溯到1969年。
” After several training sessions, monkeys could increase the activity of newly isolated cells by 50 to 500% above rates before reinforcement.” Fascinating.
“经过几次训练后,猴子可以将新分离的细胞的活性比强化前提高 50% 到 500%。”迷人。
Brain is very [inaudible 01:46:45].
大脑非常[听不清 01:46:45]。
And so from here, the number of experiments grew.
从这里开始,实验的数量开始增加。
Yeah.
是的。
1:46:49 Number of experiments, as well as set of tools to interface with the brain have just exploded.
实验的数量以及与大脑接口的工具集都呈爆炸式增长。
And also, just understanding the neural code and how some of the cortical layers and the functions are organized.
而且,只需了解神经代码以及一些皮质层和功能的组织方式即可。
So the other paper that is pretty seminal, especially in the motor decoding, was this paper in the 1980s from Georgopoulos that discovered that there’s this thing called motor tuning curve.
因此,另一篇非常具有开创性的论文,尤其是在电机解码方面,是 Georgopoulos 在 20 世纪 80 年代发表的论文,它发现了一种叫做电机调谐曲线的东西。
So what are motor tuning curves?
那么什么是电机调谐曲线呢?
It’s the fact that there are neurons in the motor cortex of mammals, including humans, that have a preferential direction that causes them to fire.
事实上,哺乳动物(包括人类)的运动皮层中的神经元具有导致它们放电的优先方向。
So what that means is, there are a set of neurons that would increase their spiking activities when you’re thinking about moving to the left, right, up, down, and any of those vectors.
所以这意味着,当你考虑向左、向右、向上、向下以及任何这些向量移动时,有一组神经元会增加它们的尖峰活动。
And based on that, you could start to think, well, if you can’t identify those essential eigenvectors, you can do a lot.
基于此,你可以开始思考,好吧,如果你不能识别那些基本的特征向量,你可以做很多事情。
And you can actually use that information for actually decoding someone’s intended movement from the cortex.
你实际上可以使用这些信息来从皮层解码某人的预期运动。
So that was a very, very seminal paper that showed that there is some sort of code that you can extract, especially in the motor cortex.
所以这是一篇非常非常具有开创性的论文,它表明你可以提取某种代码,特别是在运动皮层中。
So there’s signal there.
所以那里有信号。
1:48:11 And if you measure the electrical signal from the brain that you could actually figure out what the intention was.
如果你测量大脑的电信号,你实际上可以弄清楚意图是什么。
Correct.
正确的。
1:48:20 Yeah, not only electrical signals, but electrical signals from the right set of neurons that give you these preferential direction.
是的,不仅是电信号,还有来自正确神经元组的电信号,它们可以为您提供这些优先方向。
Okay.
好的。
1:48:29 So going slowly towards Neuralink, one interesting question is, what do we understand on the BCI front, on invasive versus non-invasive, from this line of work?
因此,慢慢走向 Neuralink,一个有趣的问题是,我们对 BCI 前沿、侵入性与非侵入性这一工作的理解是什么?
How important is it to park next to the neuron?
停在神经元旁边有多重要?
What does that get you?
这会给你带来什么?
That answer fundamentally depends on what you want to do with it.
这个答案从根本上取决于你想用它做什么。
1:48:49 There’s actually incredible amount of stuff that you can do with EEG and electrocortical graph, ECOG, which actually doesn’t penetrate the cortical layer or parenchyma, but you place a set of electrodes on the surface of the brain.
实际上,你可以使用脑电图和皮层电图(ECOG)做大量的事情,它实际上不会穿透皮质层或实质,但你可以在大脑表面放置一组电极。
So the thing that I’m personally very interested in is just actually understanding and being able to just really tap into the high resolution, high fidelity, understanding of the activities that are happening at the local level.
因此,我个人非常感兴趣的是真正理解并能够真正利用高分辨率、高保真度来理解当地正在发生的活动。
And we can get into biophysics, but just to step back to use analogy, because analogy here can be useful, and sometimes it’s a little bit difficult to think about electricity.
我们可以进入生物物理学,但只是退一步使用类比,因为类比在这里可能有用,有时思考电有点困难。
At the end of the day, we’re doing electrical recording that’s mediated by ionic currents, movements of these charged particles, which is really, really hard for most people to think about.
归根结底,我们正在进行的是由离子电流、这些带电粒子的运动介导的电记录,这对大多数人来说真的很难想象。
1:49:45 But turns out, a lot of the activities that are happening in the brain and the frequency bandwidth with which that’s happening, is actually very, very similar to sound waves and our normal conversation audible range.
但事实证明,大脑中发生的许多活动以及发生这些活动的频率带宽实际上与声波和我们正常对话的可听范围非常非常相似。
So the analogy that typically is used in the field is, if you have a football stadium, there’s a game going on.
因此,在该领域通常使用的类比是,如果你有一个足球场,那就有一场比赛正在进行。
If you stand outside the stadium, you maybe get a sense of how the game is going based on the cheers and the boos of the home crowd, whether the team is winning or not.
如果你站在体育场外,你也许可以根据主场球迷的欢呼声和嘘声来了解比赛的进展情况,无论球队是否获胜。
But you have absolutely no idea what the score is, you have absolutely no idea what individual audience or the players are talking or saying to each other, what the next play is, what the next goal is.
但你完全不知道比分是多少,你完全不知道个别观众或球员在互相交谈或说些什么,下一场比赛是什么,下一个目标是什么。
So what you have to do is you have to drop the microphone into the stadium and then get near the source into the individual chatter.
所以你要做的就是把麦克风扔进体育场,然后靠近声源进入个人的谈话声。
In this specific example, you would want to have it right next to where the huddle is happening.
在这个特定的示例中,您可能希望将其放置在拥挤发生的地方旁边。
1:50:47 So I think that’s kind of a good illustration of what we’re trying to do when we say invasive or minimally invasive or implanted brain computer interfaces versus non-invasive or non-implanted brain interfaces.
所以我认为,当我们说侵入性或微创或植入式脑机接口与非侵入性或非植入式脑机接口时,这很好地说明了我们正在努力做的事情。
It’s basically talking about where do you put that microphone and what can you do with that information.
它基本上是在讨论你把麦克风放在哪里以及你可以用这些信息做什么。
So what is the biophysics of the read and write communication that we’re talking about here as we now step into the efforts at Neuralink?
那么,当我们现在开始 Neuralink 的工作时,我们在这里讨论的读写通信的生物物理学是什么?
Yeah.
是的。
1:51:18 So brain is made up of these specialized cells called neurons.
因此,大脑是由这些称为神经元的特殊细胞组成的。
There’s billions of them, tens of billions, sometimes people call it a hundred billion, that are connected in this complex yet dynamic network that are constantly remodeling.
有数十亿、数百亿,有时人们称之为千亿,它们连接在这个不断重塑的复杂而动态的网络中。
They’re changing their synaptic weights, and that’s what we typically call neuroplasticity.
它们正在改变突触权重,这就是我们通常所说的神经可塑性。
And the neurons are also bathed in this charged environment that is latent with many charge molecules like potassium ions, sodium ions, chlorine ions.
神经元也沐浴在这种带电环境中,潜藏着许多带电分子,如钾离子、钠离子、氯离子。
And those actually facilitate these, through ionic current, communication between these different networks.
这些实际上通过离子电流促进了这些不同网络之间的通信。
1:52:08 And when you look at a neuron as well, they have these membrane with a beautiful, beautiful protein structure called the voltage selective ion channels, which in my opinion, is one of nature’s best inventions.
当你观察神经元时,它们的膜具有美丽的蛋白质结构,称为电压选择性离子通道,在我看来,这是大自然最好的发明之一。
In many ways, if you think about what they are, they’re doing the job of a modern day transistors.
从很多方面来说,如果你考虑一下它们是什么,就会发现它们正在做现代晶体管的工作。
Transistors are nothing more, at the end of the day, than a voltage-gated conduction channel.
归根结底,晶体管只不过是一个电压门控传导通道。
And nature found a way to have that very, very early on in its evolution.
大自然在其进化的非常非常早期就找到了一种方法来实现这一点。
And as we all know, with the transistor, you can have many, many computation and a lot of amazing things that we have access to today.
众所周知,通过晶体管,你可以进行很多很多的计算,以及我们今天可以获得的很多令人惊奇的东西。
So I think it’s one of those, just as a tangent, just a beautiful, beautiful invention that the nature came up with, these voltage-gated ion channels.
所以我认为这是其中之一,就像切线一样,只是大自然想出的一个美丽的发明,这些电压门控离子通道。
I suppose there’s, on the biological of it, every level of the complexity, of the hierarchy, of the organism, there’s going to be some mechanisms for storing information and for doing computation.
我想,从生物学的角度来看,有机体的各个层次的复杂性、层次结构,都会有一些存储信息和进行计算的机制。
1:53:02 And this is just one such way.
这只是其中一种方式。
But to do that with biological and chemical components is interesting.
但用生物和化学成分来做到这一点很有趣。
Plus, when neurons, it’s not just electricity, it’s chemical communication, it’s also mechanical.
另外,对于神经元来说,它不仅仅是电,它是化学通讯,它也是机械通讯。
These are actual objects that vibrate, they move.
这些是振动、移动的实际物体。
It’s all of that.
这就是全部。
Yeah, actually there’s a lot of really, really interesting physics that are involved in kind of going back to my work on ultrasound during grad school, there were groups and there are still groups looking at ways to cause neurons to actually fire an action potential using ultrasound wave.
是的,实际上有很多非常非常有趣的物理学涉及到我在研究生院期间关于超声波的工作,有一些小组并且仍然有一些小组正在研究如何使用超声波使神经元真正激发动作电位。
1:53:36 And the mechanism to which that’s happening is still unclear, as I understand.
据我了解,发生这种情况的机制仍不清楚。
It may just be that you’re imparting some sort of thermal energy and that causes cells to depolarize in some interesting ways.
可能只是你传递了某种热能,导致细胞以一些有趣的方式去极化。
But there are also these ion channels, or even membranes, that actually just open up as pore as they’re being mechanically shook, vibrated.
但也有这些离子通道,甚至是膜,它们实际上只是在受到机械摇动、振动时像毛孔一样打开。
There’s just a lot of elements of these, move particles, which again, that’s governed by diffusion physics, movements of particles.
其中有很多元素,移动粒子,这又是由扩散物理学和粒子运动控制的。
And there’s also a lot of interesting physics there.
那里还有很多有趣的物理学。
Also, not to mention, as Roger Penrose talks about, there might be some beautiful weirdness in the quantum mechanical effects of all of this.
另外,更不用说,正如罗杰·彭罗斯所说,所有这一切的量子力学效应可能存在一些美丽的怪异。
Oh, yeah.
哦,是的。
And he actually believes that consciousness might emerge from the quantum mechanical effects there.
他实际上相信意识可能是从那里的量子力学效应中产生的。
1:54:44 So there’s physics, there’s chemistry, there’s biology, all of that is going on there.
所以有物理学、有化学、有生物学,所有这些都在那里发生。
Oh, yeah.
哦,是的。
1:54:54 Yes, there’s a lot of levels of physics that you can dive into.
是的,您可以深入研究很多级别的物理知识。
But yeah, in the end, you have these membranes with these voltage-gated ion channels that selectively let these charged molecules that are in the extracellular matrix, in and out.
但是,是的,最终,这些膜带有这些电压门控离子通道,可以选择性地让细胞外基质中的这些带电分子进出。
And these neurons generally have these resting potential where there’s a voltage difference between inside the cell and outside the cell.
这些神经元通常具有静息电位,其中细胞内部和细胞外部之间存在电压差。
And when there’s some sort of stimuli that changes the state such that they need to send information to the downstream network, you start to see these orchestration of these different molecules going in and out of these channels.
当某种刺激改变状态从而需要将信息发送到下游网络时,您开始看到这些不同分子进出这些通道的编排。
They also open up.
他们也开放。
More of them open up once it reaches some threshold, to a point where you have a depolarizing cell that sends an action potential.
一旦达到某个阈值,就会有更多的细胞打开,达到一个可以发送动作电位的去极化细胞的程度。
So it’s just a very beautiful kind of orchestration of these molecules.
所以这只是这些分子的一种非常美丽的编排。
And what we’re trying to do when we place an electrode or parking it next to a neuron is that you’re trying to measure these local changes in the potential.
当我们放置电极或将其停放在神经元旁边时,我们试图做的是测量这些局部电位变化。
Again, mediated by the movements of the ions.
再次,由离子的运动介导。
1:56:17 And what’s interesting, as I mentioned earlier, there’s a lot of physics involved.
有趣的是,正如我之前提到的,其中涉及很多物理知识。
And the two dominant physics for this electrical recording domain is diffusion physics and electromagnetism.
该电记录领域的两个主导物理学是扩散物理学和电磁学。
And where one dominates, where Maxwell’s equation dominates versus Fick’s law dominates depends on where your electrode is.
麦克斯韦方程占主导地位与菲克定律占主导地位取决于你的电极在哪里。
If it’s close to the source, mostly electromagnetic-based.
如果它靠近源头,则主要是基于电磁的。
When you’re further away from it, it’s more diffusion-based.
当你离它更远时,它就更加基于扩散。
So essentially, when you’re able to park it next to it, you can listen in on those individual chatter and those local changes in the potential.
所以本质上,当你能够把它停在它旁边时,你可以倾听那些个人的闲聊和潜力的局部变化。
And the type of signal that you get are these canonical textbook neural spiking waveform.
您获得的信号类型是这些规范教科书的神经尖峰波形。
The moment you’re further away, and based on some of the studies that people have done, Christof Koch’s lab, and others, once you’re away from that source by roughly around a hundred micron, which is about a width of a human hair, you no longer hear from that neuron.
当你距离更远时,根据人们所做的一些研究,克里斯托夫·科赫的实验室和其他人,一旦你远离那个源大约一百微米,大约是人类头发的宽度,你就不再听到那个神经元的声音。
You’re no longer able to have the system sensitive enough to be able to record that particular local membrane potential change in that neuron.
您不再能够让系统足够灵敏来记录该神经元中特定的局部膜电位变化。
1:57:36 And just to give you a sense of scale also, when you look at a hundred micron voxel, so a hundred micron by a hundred micron by a hundred micron box in a brain tissue, there’s roughly around 40 neurons, and whatever number of connections that they have.
为了给你一种规模感,当你观察 100 微米的体素时,即脑组织中 100 微米×100 微米×100 微米的盒子,大约有 40 个神经元,以及它们具有的连接数量。
So there’s a lot in that volume of tissue.
所以这个组织体积里有很多东西。
So the moment you’re outside of that, there’s just no hope that you’ll be able to detect that change from that one specific neuron that you may care about.
因此,一旦你脱离了这种状态,你就不可能从你可能关心的某个特定神经元中检测到这种变化。
But as you’re moving about this space, you’ll be hearing other ones.
但当您在这个空间中移动时,您会听到其他声音。
1:58:03 So if you move another a hundred micron, you’ll be hearing chatter from another community.
因此,如果你再移动一百微米,你就会听到来自另一个社区的喋喋不休。
Correct.
正确的。
And so the whole sense is, you want to place as many as possible electrodes, and then you’re listening to the chatter.
所以整体的感觉是,你想要放置尽可能多的电极,然后你就可以听到喋喋不休的声音。
Yeah, you want to listen to the chatter.
是的,你想听闲聊。
1:58:20 And at the end of the day, you also want to basically let the software do the job of decoding.
归根结底,您还想让软件完成解码工作。
And just to kind of go to why ECOG and EEG work at all.
只是想了解一下 ECOG 和 EEG 为何有效。
When you have these local changes, obviously it’s not just this one neuron that’s activating, there’s many, many other networks that are activating all the time.
当你发生这些局部变化时,显然不仅仅是这个神经元在激活,还有很多很多其他网络一直在激活。
And you do see sort of a general change in the potential of this electrode, this charged medium, and that’s what you’re recording when you’re farther away.
你确实看到了这个电极、这个带电介质的电势的总体变化,这就是你在更远的地方记录到的。
I mean, you still have some reference electrode that’s stable in the brain, that’s just electro- active organ, and you’re seeing some combination, aggregate action, potential changes, and then you can pick it up.
我的意思是,你的大脑中仍然有一些稳定的参考电极,那只是电活性器官,你会看到一些组合、聚合作用、潜在的变化,然后你就可以拿起它。
It’s a much slower changing signals.
这是一个变化缓慢得多的信号。
But there are these canonical oscillations and waves like gamma waves, beta waves, when you sleep, that can be detected because there’s sort of a synchronized global effect of the brain that you can detect.
但是,当你睡觉时,可以检测到这些典型的振荡和波,例如伽马波、β波,因为你可以检测到大脑的同步全局效应。
And the physics of this go, if we really want to go down that rabbit hole, there’s a lot that goes on in terms of why diffusion physics at some point dominates when you’re further away from the source.
而这个过程的物理学,如果我们真的想深入那个兔子洞,那么当你远离源头时,为什么扩散物理学在某些时候占主导地位,有很多事情会发生。
It is just a charged medium.
它只是一种带电介质。
So similar to how when you have electromagnetic waves propagating in atmosphere or in a charged medium like a plasma, there’s this weird shielding that happens that actually further attenuates the signal as you move away from it.
与电磁波在大气或等离子体等带电介质中传播时类似,会发生这种奇怪的屏蔽,当您远离信号时,信号实际上会进一步衰减。
So yeah, you see, if you do a really, really deep dive on the signal attenuation over distance, you start to see one over R square in the beginning and then exponential drop off, and that’s the knee at which you go from electromagnetism dominating to diffusion physic dominating.
所以,是的,你看,如果你对信号随距离的衰减进行非常非常深入的研究,你会开始看到一开始超过 R 平方,然后呈指数下降,这就是你从电磁主导转向扩散物理主导的拐点。
But once again, with the electrodes, the biophysics that you need to understand is not as deep because no matter where you’re placing it, you’re listening to a small crowd of local neurons.
但再一次,对于电极,你需要了解的生物物理学并不那么深,因为无论你把它放在哪里,你都会听到一小群局部神经元的声音。
Correct, yeah.
正确,是的。
2:00:32 So once you penetrate the brain, you’re in the arena, so to speak.
所以,可以这么说,一旦你穿透了大脑,你就进入了竞技场。
And there’s a lot of neurons.
而且有很多神经元。
There are many, many of them.
有很多很多。
But then again, there’s a whole field of neuroscience that’s studying how the different groupings, the different sections of the seating in the arena, what they usually are responsible for, which is where the metaphor probably falls apart because the seating is not that organized in an arena.
但话又说回来,整个神经科学领域都在研究竞技场中座位的不同分组、不同部分,以及它们通常负责什么,这就是这个比喻可能不成立的地方,因为竞技场中的座位并不是那么有组织。
Also, most of them are silent.
而且,大多数人都是沉默的。
2:00:56 They don’t really do much.
他们实际上并没有做太多事情。
Or their activities are…
或者他们的活动是……
You have to hit it with just the right set of stimulus.
你必须用正确的刺激来达到目的。
So they’re usually quiet.
所以他们通常都很安静。
They’re usually very quiet.
他们通常很安静。
2:01:09 Similar to dark energy and dark matter, there’s dark neurons.
与暗能量和暗物质类似,也有暗神经元。
What are they all doing?
他们都在做什么?
When you place these electrodes, again, within this hundred micron volume, you have 40 or so neurons.
当你再次将这些电极放置在这百微米的体积内时,你就会有 40 个左右的神经元。
Why do you not see 40 neurons?
为什么你看不到 40 个神经元?
Why do you see only a handful?
为什么你只看到少数?
What is happening there?
那里发生了什么?
Well, they’re mostly quiet, but when they speak, they say profound shit.
嗯,他们大多都很安静,但当他们说话时,他们会说一些深刻的废话。
2:01:25 That’s the way I’d like to think about it.
这就是我想考虑的方式。
Anyway, before we zoom in even more, let’s zoom out.
不管怎样,在我们进一步放大之前,让我们先缩小一下。
So how does Neuralink work from the surgery to the implant, to the signal and the decoding process, and the human being able to use the implant to actually affect the world outside?
那么 Neuralink 从手术到植入,再到信号和解码过程是如何工作的,以及人类如何能够使用植入物来实际影响外面的世界呢?
And all of this, I’m asking in the context of, there’s a gigantic historic milestone that Neuralink just accomplished in January of this year.
所有这一切,我问的是,Neuralink 在今年 1 月刚刚实现了一个巨大的历史性里程碑。
Putting a Neuralink implant in the first human being, Noland.
将 Neuralink 植入物植入第一个人诺兰德体内。
And there’s been a lot to talk about there about his experience because he’s able to describe all the nuance and the beauty and the fascinating complexity of that experience of everything involved.
关于他的经历有很多值得谈论的地方,因为他能够描述所涉及的一切经历的所有细微差别、美丽和令人着迷的复杂性。
But on the technical level, how does Neuralink work?
但从技术层面来说,Neuralink 是如何工作的呢?
So there are three major components to the technology that we’re building.
因此,我们正在构建的技术由三个主要组成部分组成。
2:02:26 One is the device, the thing that’s actually recording these neural chatters.
一是设备,它实际上记录这些神经的喋喋不休。
We call it N1 Implant or The Link.
我们称之为 N1 植入物或 The Link。
And we have a surgical robot that’s actually doing an implantation of these tiny, tiny wires that we call threads that are smaller than human hair.
我们有一个外科手术机器人,它实际上正在植入这些非常非常小的电线,我们称之为比人类头发还小的线。
And once everything is surgerized, you have these neural signals, these spiking neurons, that are coming out of the brain, and you need to have some sort of software to decode what the users intend to do with that.
一旦一切都经过手术,你就会得到这些从大脑发出的神经信号,这些尖峰神经元,你需要某种软件来解码用户打算用它做什么。
So there’s what’s called the Neuralink Application or B1 App that’s doing that translation.
因此,有一种所谓的 Neuralink 应用程序或 B1 应用程序正在执行这种翻译。
It’s running the very, very simple machine learning model that decodes these inputs that are neural signals and then convert it to a set of outputs that allows our first participant, Noland, to be able to control a cursor on the screen.
它运行非常非常简单的机器学习模型,对这些神经信号输入进行解码,然后将其转换为一组输出,使我们的第一个参与者诺兰能够控制屏幕上的光标。
And this is done wirelessly?
这是无线完成的吗?
And this is done wirelessly.
这是通过无线方式完成的。
2:03:33 So our implant is actually a two-part.
所以我们的植入物实际上是由两部分组成。
The link has these flexible tiny wires called threads that have multiple electrodes along its length.
该链接有这些称为线的柔性细线,沿其长度有多个电极。
And they’re only inserted into the cortical layer, which is about three to five millimeters in a human brain, in the motor cortex region.
它们只插入到运动皮层区域的皮层中,皮层在人脑中大约三到五毫米。
That’s where the intention for movement lies in.
这就是运动的意图所在。
And we have 64 of these threads, each thread having 16 electrodes along the span of three to four millimeters, separated by 200 microns.
我们有 64 根这样的线,每根线有 16 个电极,跨度为 3 到 4 毫米,间距为 200 微米。
So you can actually record along the depth of the insertion.
所以你实际上可以沿着插入的深度进行记录。
And based on that signal, there’s custom integrated circuit or ASIC that we built that amplifies the neural signals that you’re recording and then digitizing it and then has some mechanism for detecting whether there was an interesting event that is a spiking event, and decide to send that or not send that through Bluetooth to an external device, whether it’s a phone or a computer that’s running this Neuralink application.
基于该信号,我们构建了定制集成电路或 ASIC,放大您正在记录的神经信号,然后将其数字化,然后具有某种机制来检测是否存在有趣的事件,即尖峰事件,并决定是否通过蓝牙将其发送到外部设备,无论是运行此 Neuralink 应用程序的手机还是计算机。
So there’s onboard signal processing already just to decide whether this is an interesting event or not.
因此,机载信号处理已经可以决定这是否是一个有趣的事件。
2:04:50 So there is some computational power on board in addition to the human brain?
那么除了人脑之外,船上还有一些计算能力吗?
Yeah.
是的。
2:05:00 So it does the signal processing to really compress the amount of signal that you’re recording.
因此,它会进行信号处理,以真正压缩您正在记录的信号量。
So we have a total of thousand electrodes sampling at just under 20 kilohertz with 10 bit each.
因此,我们总共有 1000 个电极,采样频率略低于 20 kHz,每个电极 10 位。
So that’s 200 megabits that’s coming through to the chip from thousand channel simultaneous neural recording.
因此,这是从千通道同步神经记录传输到芯片的 200 兆比特。
And that’s quite a bit of data, and there are technology available to send that off wirelessly.
这是相当多的数据,并且有技术可以无线发送这些数据。
But being able to do that in a very, very thermally-constrained environment that is a brain.
但能够在一个非常非常热受限的大脑环境中做到这一点。
So there has to be some amount of compression that happens to send off only the interesting data that you need, which in this particular case for motor decoding is, occurrence of a spike or not.
因此,必须进行一定程度的压缩,以便仅发送您需要的有趣数据,在电机解码的特殊情况下,即是否出现尖峰。
And then being able to use that to decode the intended cursor movement.
然后能够使用它来解码预期的光标移动。
So the implant itself processes it, figures out whether a spike happened or not with our spike detection algorithm, and then sends it off, packages it, sends it off through Bluetooth to an external device that then has the model to decode, okay, based on these spiking inputs, did Noland wish to go up, down, left, right, or click or right click or whatever.
因此,植入物本身会对其进行处理,通过我们的尖峰检测算法确定尖峰是否发生,然后将其发送、打包,通过蓝牙将其发送到外部设备,然后由模型进行解码,好吧,根据这些尖峰输入,诺兰是否希望向上、向下、向左、向右,或单击或右键单击或其他任何操作。
All of this is really fascinating, but let’s stick on the N1 Implant itself.
所有这一切都非常令人着迷,但让我们继续关注 N1 植入物本身。
2:06:23 So the thing that’s in the brain.
所以大脑里的东西。
So I’m looking at a picture of it, there’s an enclosure, there’s a charging coil, so we didn’t talk about the charging, which is fascinating.
所以我正在看它的图片,有一个外壳,有一个充电线圈,所以我们没有谈论充电,这很有趣。
The battery, the power electronics, the antenna.
电池、电力电子设备、天线。
Then there’s the signal processing electronics.
然后是信号处理电子设备。
I wonder if there’s more kinds of signal processing you can do?
我想知道是否可以进行更多种类的信号处理?
That’s another question.
那是另一个问题了。
And then there’s the threads themselves with the enclosure on the bottom.
然后是螺纹本身,外壳位于底部。
So maybe to ask about the charging.
所以也许要问一下充电的问题。
So there’s an external charging device?
那么有外接充电设备吗?
Yeah, there’s an external charging device.
是的,有一个外部充电设备。
2:07:03 So yeah, the second part of the implant, the threads are the ones, again, just the last three to five millimeters are the ones that are actually penetrating the cortex.
所以,是的,植入物的第二部分,即螺纹,同样,最后三到五毫米是真正穿透皮质的螺纹。
Rest of it is, actually most of the volume, is occupied by the battery, rechargeable battery, and it’s about a size of a quarter.
剩下的,实际上大部分的体积,都被电池,充电电池占据了,大约有四分之一的大小。
I actually have a device here if you want to take a look at it.
我这里实际上有一个设备,如果你想看一下的话。
This is the flexible thread component of it, and then this is the implant.
这是它的柔性螺纹组件,然后这是植入物。
So it’s about a size of a US quarter.
所以它大约相当于美国25美分硬币的大小。
It’s about nine millimeters thick.
它大约有九毫米厚。
So basically this implant, once you have the craniectomy and the directomy, threads are inserted, and the hole that you created, this craniectomy, gets replaced with that.
所以基本上这个植入物,一旦你进行了颅骨切除术和直切术,就会插入线,并且你创建的孔,这个颅骨切除术,会被替换。
So basically that thing plugs that hole, and you can screw in these self-drilling cranial screws to hold it in place.
所以基本上这个东西会堵塞那个洞,你可以拧入这些自钻颅骨螺钉将其固定到位。
And at the end of the day, once you have the skin flap over, there’s only about two to three millimeters that’s obviously transitioning off of the top of the implant to where the screws are.
一天结束时,一旦你将皮瓣翻过来,就会发现只有大约两到三毫米的部分明显从植入物顶部过渡到螺钉所在的位置。
And that’s the minor bump that you have.
这就是你所遇到的小问题。
Those threads look tiny.
这些线看起来很小。
2:08:22 That’s incredible.
那真是难以置信。
That is really incredible.
这实在是太不可思议了。
That is really incredible.
这实在是太不可思议了。
And also, you’re right, most of the actual volume is the battery.
而且,你是对的,大部分实际体积是电池。
This is way smaller than I realized.
这比我意识到的要小得多。
Also, the threads themselves are quite strong.
而且,线程本身非常坚固。
They look strong.
他们看起来很坚强。
And the thread themselves also has a very interesting feature at the end of it called the loop.
线程本身还有一个非常有趣的功能,称为循环。
2:08:42 And that’s the mechanism to which the robot is able to interface and manipulate this tiny hair-like structure.
这就是机器人能够连接和操纵这种微小的毛发状结构的机制。
And they’re tiny.
而且它们很小。
2:08:55 So what’s the width of a thread?
那么螺纹的宽度是多少?
So the width of a thread starts from 16 micron and then tapers out to about 84 micron.
因此,螺纹的宽度从 16 微米开始,然后逐渐减小到约 84 微米。
2:08:58 So average human hair is about 80 to 100 micron in width.
因此,人类头发的平均宽度约为 80 至 100 微米。
This thing is amazing.
这件事太神奇了。
2:09:13 This thing is amazing.
这件事太神奇了。
Yes, most of the volume is occupied by the battery, rechargeable lithium ion cell.
是的,大部分体积被电池、可充电锂离子电池占据。
2:09:16 And the charging is done through inductive charging, which is actually very commonly used.
而且充电是通过感应充电来完成的,这其实是很常用的。
Your cell phone, most cell phones, have that.
你的手机,大多数手机,都有这个功能。
The biggest difference is that for us, usually when you have a phone and you want to charge it on the charging pad, you don’t really care how hot it gets.
最大的区别是,对我们来说,通常当你有手机并且想在充电板上充电时,你并不真正关心它有多热。
Whereas, in for us, it matters.
然而,对我们来说,这很重要。
There is a very strict regulation and good reasons to not actually increase the surrounding tissue temperature by two degrees Celsius.
有一个非常严格的规定和充分的理由实际上不会将周围组织的温度增加两摄氏度。
So there’s actually a lot of innovation that is packed into this to allow charging of this implant without causing that temperature threshold to reach.
因此,实际上包含了很多创新,可以在不达到温度阈值的情况下为该植入物充电。
2:10:03 And even small things like, you see this charging coil and what’s called a ferrite shield.
甚至像这样的小东西,你会看到这个充电线圈和所谓的铁氧体屏蔽。
So without that ferrite shield, what you end up having when you have resonant inductive charging is that the battery itself is a metallic can, and you form these eddy currents from external charger and that causes heating, and that actually contributes to inefficiency in charging.
因此,如果没有铁氧体屏蔽,当进行谐振感应充电时,电池本身就是一个金属罐,并且从外部充电器形成这些涡流,从而导致发热,这实际上会导致充电效率低下。
So this ferrite shield, what it does, is that it actually concentrate that field line away from the battery and then around the coil that’s actually wrapped around it.
因此,这个铁氧体屏蔽的作用是,它实际上将磁场线集中在远离电池的地方,然后集中在实际缠绕在其周围的线圈周围。
There’s a lot of really fascinating design here to make it, I mean, you’re integrating a computer into a biological, a complex biological system.
这里有很多非常有趣的设计,我的意思是,你正在将计算机集成到生物、复杂的生物系统中。
Yeah, there’s a lot of innovation here.
是的,这里有很多创新。
2:10:52 I would say that part of what enabled this was just the innovations in the wearable.
我想说,这一切的部分原因在于可穿戴设备的创新。
There’s a lot of really, really powerful tiny, low-power microcontrollers, temperature sensors, or various different sensors and power electronics.
有很多非常非常强大的微型、低功耗微控制器、温度传感器或各种不同的传感器和电力电子设备。
A lot of innovation really came in the charging coil design, how this is packaged, and how do you enable charging such that you don’t really exceed that temperature limit, which is not a constraint for other devices out there.
许多创新确实来自于充电线圈的设计、如何封装,以及如何实现充电,这样就不会真正超过温度限制,这对其他设备来说不是一个限制。
So let’s talk about the threads themselves.
那么让我们来谈谈线程本身。
2:11:28 Those tiny, tiny, tiny things.
那些微小的、微小的、微小的东西。
So how many of them are there?
那么他们有多少人呢?
You mentioned a thousand electrodes.
你提到了一千个电极。
How many threads are there and what do the electrodes have to do with the threads?
有多少根螺纹,电极与螺纹有什么关系?
So the current instantiation of the device has 64 threads, and each thread has 16 electrodes for a total of 1,024 electrodes that are capable of both recording and stimulating.
因此,该设备的当前实例有 64 个线程,每个线程有 16 个电极,总共 1,024 个电极能够同时记录和刺激。
2:11:42 And the thread is basically this polymer-insulated wire.
线基本上就是这种聚合物绝缘线。
The metal conductor is the kind of a tiramisu cake of ti, plat, gold, plat, ti and they’re very, very tiny wires.
金属导体是一种提拉米苏蛋糕,由钛、铂、金、铂、钛组成,它们是非常非常细的电线。
Two micron in width.
宽度为两微米。
So two one-millionth of meter.
所以百万分之二米。
It’s crazy that that thing I’m looking at has the polymer-insulation, has the conducting material and has 16 electrodes at the end of it.
太疯狂了,我看到的那个东西有聚合物绝缘体、导电材料,并且末端有 16 个电极。
On each of those thread.
在每个线程上。
Yeah, on each of those threads.
是的,在每一个线程上。
Correct.
正确的。
16, each one of those 64.
16 个,这 64 个中的每一个。
Yes, you’re not going to be able to see it with naked eyes.
是的,你无法用肉眼看到它。
And to state the obvious, or maybe for people who are just listening, they’re flexible?
说实话,或者对于那些只是在听的人来说,他们很灵活?
Yes, that’s also one element that was incredibly important for us.
是的,这也是对我们来说非常重要的一个因素。
2:12:48 So each of these threads are now, as I mentioned, 16 micron in width, and then they taper to 84 micron, but in thickness they’re less than five micron.
因此,正如我提到的,现在每根螺纹的宽度均为 16 微米,然后逐渐变细至 84 微米,但厚度小于 5 微米。
And in thickness it’s mostly a polyimide at the bottom and this metal track and then another polyimide.
从厚度上看,它的底部主要是聚酰亚胺,金属轨道然后是另一个聚酰亚胺。
So two micron of polyimide, 400 nanometer of this metal stack and two micron of polyimide sandwiched together to protect it from the environment that is 37 degrees C bag of salt water.
因此,将 2 微米的聚酰亚胺、400 纳米的金属堆叠和 2 微米的聚酰亚胺夹在一起,以保护其免受 37 摄氏度的盐水袋环境的影响。
Maybe can you speak to some interesting aspects of the material design here?
也许您能在这里谈谈材料设计的一些有趣的方面吗?
2:13:26 What does it take to design a thing like this and to be able to manufacture a thing like this?
设计这样的东西并能够制造这样的东西需要什么?
For people who don’t know anything about this kind of thing.
对于对这种事情一无所知的人来说。
So the material selection that we have is not, I don’t think it was particularly unique.
所以我们的材料选择不是,我不认为它是特别独特的。
2:13:40 There were other labs and there are other labs that are kind of looking at similar material stack.
还有其他实验室也在研究类似的材料堆栈。
There’s kind of a fundamental question, and still needs to be answered, around the longevity and reliability of these microelectrodes that we call, compared to some of the other more conventional neural interfaces devices that are intracranial, so penetrating the cortex, that are more rigid, like the Utah Array.
与其他一些更传统的颅内神经接口设备相比,这些微电极的寿命和可靠性仍然需要回答,而且仍然需要回答,这些微电极位于颅内,因此穿透皮层,更加刚性,如犹他阵列。
That are these four by four millimeter kind of silicon shank that have exposed recording site at the end of it.
这就是这种四乘四毫米的硅柄,其末端暴露了记录位置。
And that’s been kind of the innovation from Richard Normann back in 1997.
这就是 Richard Normann 在 1997 年的创新。
It’s called the Utah Array because he was at University of Utah.
它被称为犹他阵列,因为他在犹他大学。
And what does the Utah Array look like?
犹他阵列是什么样子的?
2:14:36 So it’s a rigid type of [inaudible 02:14:41]?
所以这是一种僵化的类型 [听不清 02:14:41]?
Yeah, so we can actually look it up.
是的,所以我们实际上可以查一下。
2:14:40 Yeah, so it’s a bed of needle.
是的,所以这是一个针床。
There’s-
有——
Okay, go ahead.
好的,继续吧。
2:14:52 I’m sorry.
对不起。
Those are rigid shanks.
这些是刚性的柄。
Rigid, yeah, you weren’t kidding.
刚性,是的,你不是在开玩笑。
And the size and the number of shanks vary anywhere from 64 to 128.
柄的尺寸和数量从 64 到 128 不等。
2:14:57 At the very tip of it, is an exposed electrode that actually records neural signal.
在它的最顶端,是一个裸露的电极,实际上记录了神经信号。
The other thing that’s interesting to note is that unlike neural link threads that have recording electrodes that are actually exposed iridium oxide recording sites along the depth, this is only at a single depth.
另一件有趣的事情是,与具有记录电极的神经连接线程不同,记录电极实际上沿着深度暴露于氧化铱记录位点,这仅在单一深度。
So these Utah Array spokes can be anywhere between 0.5 millimeters to 1.5 millimeter, and they also have designs that are slanted.
因此,这些 Utah Array 辐条的长度可以在 0.5 毫米到 1.5 毫米之间,而且它们也有倾斜的设计。
So you can have it inserted at different depths, but that’s one of the other big differences.
因此,您可以将其插入不同的深度,但这是其他重大差异之一。
And then, the main key difference is the fact that there’s no active electronics.
然后,主要的区别是没有有源电子设备。
These are just electrodes, and then there’s a bundle of a wire that you’re seeing, and then that actually then exits the craniotomy that then has this port that you can connect to for any external electronic devices.
这些只是电极,然后是一束你看到的电线,然后实际上从开颅手术中出来,然后有一个端口,你可以连接到任何外部电子设备。
They are working on, or have, the wireless telemetry device but it still requires a through-the-skin port, that actually is one of the biggest failure modes for infection for the system.
他们正在开发或拥有无线遥测设备,但它仍然需要一个穿透皮肤的端口,这实际上是系统感染的最大故障模式之一。
What are some of the challenges associated with flexible threads?
与柔性螺纹相关的一些挑战有哪些?
2:16:06 Like for example, on the robotic side, R1, implanting those threads.
例如,在机器人方面,R1,植入这些线程。
How difficult is that task?
这项任务有多困难?
Yeah, so as you mentioned, they’re very, very difficult to maneuver by hand.
是的,正如您提到的,它们非常非常难以手动操作。
2:16:19 These Utah Arrays that you saw earlier, they’re actually inserted by a neurosurgeon actually positioning it near the site that they want.
您之前看到的这些犹他阵列实际上是由神经外科医生插入的,实际上将其放置在他们想要的位置附近。
And then there’s a pneumatic hammer that actually pushes them in.
然后有一个气动锤将它们实际推入。
So it’s a pretty simple process and they’re easy to maneuver.
所以这是一个非常简单的过程,而且很容易操作。
But for these thin-film arrays, they’re very, very tiny and flexible.
但对于这些薄膜阵列来说,它们非常非常小且灵活。
So they’re very difficult to maneuver.
所以他们很难操纵。
So that’s why we built an entire robot to do that.
这就是为什么我们建造了一个完整的机器人来做到这一点。
2:16:55 There are other reasons for why we built the robot, and that is ultimately we want this to help millions and millions of people that can benefit from this.
我们建造机器人还有其他原因,最终我们希望它能够帮助数以百万计的人从中受益。
And there just aren’t that many neurosurgeons out there.
而且那里的神经外科医生并不多。
And robots can be something that we hope can actually do large parts of the surgery.
我们希望机器人能够真正完成大部分手术。
But the robot is this entire other sort of category of product that we’re working on.
但机器人是我们正在开发的完全不同类型的产品。
And it’s essentially this multi- axis gantry system that has the specialized robot head that has all of the optics and this kind of a needle-retracting mechanism that maneuvers these threads via this loop structure that you have on the thread.
本质上,这个多轴龙门系统具有专门的机器人头,该机器人头具有所有光学器件和这种针缩回机构,可通过在线上的循环结构操纵这些线。
So the thread already has a loop structure by which you can grab it?
那么线程已经有一个循环结构,你可以通过它来抓取它?
Correct.
正确的。
So this is fascinating.
所以这很有趣。
2:17:56 So you mentioned optics.
所以你提到了光学。
So there’s a robot, R1, so for now, there’s a human that actually creates a hole in the skull.
所以有一个机器人,R1,所以现在,有一个人实际上在头骨上打了一个洞。
And then after that, there’s a computer vision component that’s finding a way to avoid the blood vessels.
之后,有一个计算机视觉组件正在寻找一种避开血管的方法。
And then you’re grabbing it by the loop, each individual thread, and placing it in a particular location to avoid the blood vessels and also choosing the depth of placement, all that.
然后你抓住它的环,每根单独的线,并将其放置在特定位置以避免血管,并选择放置深度,所有这些。
So controlling every, the 3D geometry, of the placement?
那么要控制每个 3D 几何形状吗?
Correct.
正确的。
2:18:31 So the aspect of this robot that is unique is that it’s not surgeon-assisted or human-assisted.
因此,该机器人的独特之处在于它不需要外科医生辅助或人工辅助。
It’s a semi-automatic or automatic robot.
它是一个半自动或自动机器人。
Obviously, there are human component to it, when you’re placing targets, you can always move it away from major vessels that you see.
显然,其中有人为因素,当你放置目标时,你总是可以将其移离你看到的主要船只。
But we want to get to a point where one click and it just does the surgery within minutes.
但我们希望达到这样的程度:只需点击一下,几分钟内就能完成手术。
So the computer vision component finds great targets, candidates, and the human approves them, and the robot does…
因此,计算机视觉组件找到了很好的目标、候选者,人类批准了它们,机器人也批准了……
2:18:57 Does it do one thread at a time?
它一次只执行一个线程吗?
Or does it do them [inaudible 02:19:08]?
或者它对他们有影响吗 [听不清 02:19:08]?
It does one thread at a time.
它一次执行一个线程。
2:19:07 And that’s actually also one thing that we are looking at ways to do multiple threads at a time.
这实际上也是我们正在寻找同时执行多个线程的方法的一件事。
There’s nothing stopping from it.
没有什么可以阻止它。
You can have multiple kind of engagement mechanisms.
您可以有多种参与机制。
But right now, it’s one-by-one.
但现在,却是一一的。
And we also still do quite a bit of just kind of verification to make sure that it got inserted.
我们仍然做了相当多的验证以确保它被插入。
If so, how deep?
如果有,有多深?
Did it actually match what was programmed in?
它真的与编程的内容相符吗?
And so on and so forth.
等等。
And the actual electrodes are placed at differing depths in the…
实际的电极放置在......的不同深度。
2:19:36 I mean, it’s very small differences, but differences.
我的意思是,差异很小,但是差异。
Yeah.
是的。
And so there’s some reasoning behind that, as you mentioned, it gets more varied signal.
正如您所提到的,这背后有一些原因,它会获得更加多样化的信号。
Yeah, we try to place them all around three or four millimeter from the surface.
是的,我们尝试将它们放置在距表面约三到四毫米的位置。
2:20:00 …
……
it’s three or four millimeter from the surface just because the span of the electrode, those 16 electrodes that we currently have in this version, spans roughly around three millimeters.
它距表面三到四毫米,只是因为电极的跨度(我们目前在这个版本中拥有 16 个电极)的跨度大约为 3 毫米。
So we want to get all of those in the brain.
所以我们希望将所有这些都纳入大脑中。
This is fascinating.
这很有趣。
2:20:16 Okay, so there’s a million questions here.
好的,这里有一百万个问题。
If we could zoom in specifically on the electrodes.
如果我们可以专门放大电极。
What is your sense, how many neurons is each individual electrode listening to?
您的感觉是什么?每个单独的电极监听了多少个神经元?
Yeah, each electrode can record from anywhere between zero to 40, as I mentioned earlier.
是的,正如我之前提到的,每个电极可以记录 0 到 40 之间的任何位置。
2:20:27 But practically speaking, we only see about at most two to three, and you can actually distinguish which neuron it’s coming from by the shape of the spikes.
但实际上,我们最多只能看到两到三个,而且你实际上可以通过尖峰的形状来区分它来自哪个神经元。
Oh, cool.
哦,酷。
I mentioned the spike detection algorithm that we have, it’s called BOSS algorithm, Buffer Online Spike Sorter.
我提到了我们拥有的尖峰检测算法,它被称为 BOSS 算法,Buffer Online Spike Sorter。
Nice.
好的。
It actually outputs at the end of the day six unique values, which are the amplitude of these negative going hump, middle hump, positive going hump, and then also the time at which these happen.
它实际上在一天结束时输出六个唯一值,即这些负向驼峰、中间驼峰、正向驼峰的幅度,以及这些发生的时间。
2:20:59 And from that, you can have a statistical probability estimation of, “Is that a spike?
由此,您可以进行统计概率估计,“这是一个峰值吗?
Is it not a spike?” And then based on that, you could also determine, “Oh, that spike looks different than that spike, it must come from a different neuron.”
不是尖刺吗?”然后基于此,你还可以确定,“哦,那个尖峰看起来与那个尖峰不同,它一定来自不同的神经元。”
Okay.
好的。
2:21:27 So that’s a nice signal processing step from which you can then make much better predictions about if there’s a spike, especially in this kind of context, where there could be multiple neurons screaming.
因此,这是一个很好的信号处理步骤,您可以通过它对是否存在尖峰做出更好的预测,特别是在这种可能有多个神经元尖叫的情况下。
And that that also results in you being able to compress the data better at the of the day.
这也使您能够在当天更好地压缩数据。
Yeah.
是的。
Okay, that’s-
好吧,那就是——
And just to be clear, I mean, the labs do this what’s called spike sorting.
需要明确的是,我的意思是,实验室进行了所谓的尖峰排序。
2:21:46 Usually once you have the fully digitized signals and then you run a bunch of different set of algorithms to tease apart, it’s just all of this for us is done on the device.
通常,一旦您拥有完全数字化的信号,然后运行一组不同的算法来梳理,我们的所有这些都是在设备上完成的。
On the device.
在设备上。
In a very low power, custom-built ASIC digital processing unit.
采用功耗极低的定制 ASIC 数字处理单元。
Highly heat constrained.
高度受热约束。
Highly heat constrained.
高度受热约束。
2:22:15 And the processing time from signal going in and giving you the output is less than a microsecond, which is a very, very short amount of time.
从信号输入到输出的处理时间不到一微秒,这是一个非常非常短的时间。
Oh, yeah.
哦,是的。
2:22:25 So the latency has to be super short.
所以延迟必须超短。
Correct.
正确的。
Oh, wow.
哦,哇。
2:22:28 Oh, that’s a pain in the ass.
哦,那真是令人痛苦。
That’s really tough.
这真的很难。
Yeah, latency is this huge, huge thing that you have to deal with.
是的,延迟是你必须处理的一个非常非常大的问题。
2:22:32 Right now the biggest source of latency comes from the Bluetooth, the way in which their packetized and we bin them in a 15 millisecond time window.
目前,延迟的最大来源来自蓝牙,即它们的分组方式,我们将它们分组在 15 毫秒的时间窗口中。
Oh, interesting, so it’s communication constrained.
哦,有趣,所以沟通受到限制。
2:22:44 Is there some potential innovation there on the protocol used?
所使用的协议是否有一些潜在的创新?
Absolutely.
绝对地。
Okay.
好的。
Yeah.
是的。
2:22:49 Bluetooth is definitely not our final wireless communication protocol that we want to get to.
蓝牙绝对不是我们最终想要的无线通信协议。
It’s highly-
这是高度-
Hence, the N1 and the R1.
因此,N1 和 R1。
2:22:59 I imagine that increases [inaudible 02:23:03].
我想这会增加 [听不清 02:23:03]。
Nx, Rx.
NX、Rx。
Yeah, that’s the communication protocol because Bluetooth allows you to communicate, gets farther distances than you need to, so you can go much shorter.
是的,这就是通信协议,因为蓝牙允许您进行通信,获得比您需要的更远的距离,因此您可以走得更短。
Yeah.
是的。
2:23:16 The only, well, the primary motivation for choosing Bluetooth is that, I mean, everything has Bluetooth,
选择蓝牙的唯一主要动机是,我的意思是,一切都有蓝牙,
All right, so you can talk to any device.
好的,这样您就可以与任何设备通话了。
Interoperability is just absolutely essential, especially in this early phase.
互操作性是绝对必要的,尤其是在这个早期阶段。
2:23:23 And in many ways, if you can access a phone or a computer, you can do anything.
在很多方面,如果你可以使用手机或电脑,你就可以做任何事情。
It’ll be interesting to step back and actually look at, again, the same pipeline that you mentioned for Noland.
退后一步,再次实际看看您为诺兰提到的同一条管道,这会很有趣。
2:23:35 What does this whole process look like from finding and selecting a human being, to the surgery, to the first time he’s able to use this thing?
从寻找和选择一个人,到进行手术,到他第一次能够使用这个东西,这整个过程是什么样的?
We have what’s called a patient registry that people can sign up to hear more about the updates.
我们有所谓的患者登记处,人们可以注册以了解有关更新的更多信息。
2:23:56 And that was a route to which Noland applied.
这就是诺兰申请的一条路线。
And the process is that once the application comes in, it contains some medical records, and we …
这个过程是,一旦申请进来,它包含一些医疗记录,我们......
Based on their medical eligibility, there’s a lot of different inclusion/exclusion criteria for them to meet.
根据他们的医疗资格,他们需要满足许多不同的纳入/排除标准。
2:24:22 And we go through a prescreening interview process with someone from Neuralink, and at some point we also go out to their homes to do a BCI home audit.
我们与 Neuralink 的人员进行了预筛选面试过程,有时我们还会去他们的家中进行 BCI 家庭审核。
Because one of the most revolutionary part about having this in one system that is completely wireless, is that you can use it at home.
因为将其集成到一个完全无线的系统中最具革命性的部分之一是您可以在家中使用它。
You don’t actually have to go to the lab and go to the clinic to get connectedorized to these specialized equipment that you can’t take home with you.
实际上,您不必去实验室或去诊所即可连接到这些无法带回家的专用设备。
2:24:51 So that’s one of the key elements of when we’re designing the system that we wanted to keep in mind, people hopefully would want to be able to use this every day in the comfort of their homes.
因此,这是我们在设计系统时要牢记的关键要素之一,希望人们能够每天在舒适的家中使用它。
And so part of our engagement and what we’re looking for during BCI home audit is to just understand their situation, what other assisted technology that they use.
因此,我们参与的一部分以及我们在 BCI 家庭审计期间所寻求的就是了解他们的情况以及他们使用的其他辅助技术。
And we should also step back and say that the estimate is 180,000 people live with quadriplegia in the United States, and each year an additional 18,000 suffer a paralyzing spinal cord injury.
我们还应该退一步说,据估计,美国有 180,000 人患有四肢瘫痪,而且每年还有 18,000 人遭受瘫痪脊髓损伤。
2:25:14 So these are folks who have a lot of challenges living a life in terms of accessibility, in terms of doing the things that many of us just take for granted day to day.
因此,这些人在生活中面临着很多挑战,在可及性方面,在做我们许多人每天认为理所当然的事情方面。
2:25:42 And one of the things, one of the goals of this initial study is to enable them to have digital autonomy where they by themselves can interact with a digital device using just their mind, something that you’re calling telepathy, so digital telepathy.
其中之一,这项初步研究的目标之一是使他们能够拥有数字自主权,他们自己可以仅用他们的思想与数字设备进行交互,这就是你所说的心灵感应,数字心灵感应。
Where a quadriplegic can communicate with a digital device in all the ways that we’ve been talking about.
四肢瘫痪者可以通过我们一直在谈论的所有方式与数字设备进行通信。
Control the mouse cursor enough to be able to do all kinds of stuff, including play games and tweet and all that kind of stuff.
足够控制鼠标光标,以便能够执行各种操作,包括玩游戏和发推文以及所有此类操作。
And there’s a lot of people for whom life, the basics of life, are difficult because of the things that have happened to them.
对很多人来说,生活、生活的基本要素都因为发生在他们身上的事情而变得困难。
Yeah.
是的。
2:26:24 I mean, movement is so fundamental to our existence.
我的意思是,运动对于我们的存在至关重要。
I mean, even speaking involves movement of mouth, lip, larynx.
我的意思是,即使说话也涉及嘴、嘴唇、喉部的运动。
And without that, it’s extremely debilitating.
如果没有这一点,它会非常令人衰弱。
And there are many, many people that we can help.
我们可以帮助很多很多人。
I mean, especially if you start to look at other forms of movement disorders that are not just from spinal cord injury, but from a ALS, MS, or even stroke, or just aging, that leads you to lose some of that mobility, that independence, it’s extremely debilitating.
我的意思是,特别是如果你开始关注其他形式的运动障碍,这些运动障碍不仅来自脊髓损伤,还来自肌萎缩性脊髓侧索硬化症、多发性硬化症,甚至中风,或者只是衰老,这会导致你失去一些活动能力、独立性,这是极其虚弱的。
And all of these are opportunities to help people, to help alleviate suffering, to help improve the quality of life.
所有这些都是帮助人们、帮助减轻痛苦、帮助改善生活质量的机会。
2:27:09 But each of the things you mentioned is its own little puzzle that needs to have increasing levels of capability from a device like a Neuralink device.
但你提到的每一件事都是它自己的小难题,需要像 Neuralink 设备这样的设备不断提高功能水平。
2:27:24 And so the first one you’re focusing on is, it’s just a beautiful word, telepathy.
所以你关注的第一个是,心灵感应,这是一个美丽的词。
So being able to communicate using your mind wirelessly with a digital device.
因此能够用你的思想与数字设备进行无线通信。
Can you just explain exactly what we’re talking about?
你能准确解释一下我们在说什么吗?
Yeah, I mean, it’s exactly that.
是的,我的意思是,正是如此。
2:27:40 I mean, I think if you are able to control a cursor and able to click and be able to get access to a computer or a phone, I mean, the whole world opens up to you.
我的意思是,我认为如果你能够控制光标并能够点击并能够访问计算机或手机,我的意思是,整个世界都会向你敞开。
And I mean, I guess the word “telepathy,” if you think about that as just definitionally being able to transfer information from my brain to your brain without using some of the physical faculties that we have, like voices.
我的意思是,我猜“心灵感应”这个词,如果你认为它的定义是能够将信息从我的大脑转移到你的大脑,而不需要使用我们拥有的一些身体能力,比如声音。
But the interesting thing here is I think the thing that’s not obviously clear is how exactly it works.
但有趣的是,我认为尚不清楚的是它到底是如何工作的。
2:28:13 In order to move a cursor, there’s at least a couple of ways of doing that.
为了移动光标,至少有几种方法可以做到这一点。
One is you imagine yourself maybe moving a mouse with your hand, or you can then, which no one talked about, imagine moving the cursor with your mind.
一种是你想象自己用手移动鼠标,或者你可以想象用你的意念移动光标,但没有人谈论这一点。
2:28:44 But it’s like there is a cognitive step here that’s fascinating, because you have to use the brain and you have to learn how to use the brain, and you have to figure it out dynamically because you reward yourself if it works.
但这就像这里有一个令人着迷的认知步骤,因为你必须使用大脑,你必须学习如何使用大脑,你必须动态地弄清楚它,因为如果它有效,你就会奖励自己。
I mean, there’s a step that …
我的意思是,有一个步骤......
This is just a fascinating step because you have to get the brain to start firing in the right way.
这只是一个令人着迷的步骤,因为你必须让大脑以正确的方式开始放电。
And you do that by imagining …
你通过想象来做到这一点……
Like fake it till you make it.
就像假装一样,直到你成功为止。
And all of a sudden it creates the right kind of signal that, if decoded correctly, can create the effect.
突然之间,它会产生正确的信号,如果正确解码,就可以产生效果。
And then there’s noise around that that you have to figure all of that out.
然后周围就有噪音,你必须弄清楚所有这些。
But on the human side, imagine the cursor moving is what you have to do.
但从人的角度来看,想象一下光标移动是你必须做的。
Yeah.
是的。
2:29:27 He says using the force.
他说用武力。
The force.
力量。
2:29:29 I mean, isn’t that just fascinating to you that it works?
我的意思是,它的功效难道不令你着迷吗?
To me, it’s like, holy shit, that actually works.
对我来说,天哪,这确实有效。
You could move a cursor with your mind.
你可以用意念移动光标。
As much as you’re learning to use that thing, that thing is also learning about you.
就像你在学习如何使用那个东西一样,那个东西也在了解你。
2:29:41 Our model’s constantly updating the way to say, “Oh, if someone is thinking about this sophisticated forms of spiking patterns, that actually means to do this.”
我们的模型不断更新说的方式:“哦,如果有人正在考虑这种复杂形式的尖峰模式,那实际上意味着要这样做。”
So the machine is learning about the human and the human is learning about the machine, so there is a adaptability to the signal process and the decoding step, and then there’s the adaptation of Nolan, the human being.
因此,机器正在学习人类,人类也在学习机器,因此存在对信号处理和解码步骤的适应性,然后是人类诺兰的适应。
2:30:02 The same way, if you give me a new mouse and I move it, I learn very quickly about its sensitivity, so I learn to move it slower.
同样,如果你给我一个新鼠标,我移动它,我很快就会了解它的灵敏度,因此我会学着更慢地移动它。
And then there’s other signal drift and all that kind of stuff they have to adapt to, so both are adapting to each other.
然后还有其他信号漂移以及它们必须适应的所有此类东西,因此两者都在相互适应。
Correct.
正确的。
That’s a fascinating software challenge, on both sides.
对于双方来说,这都是一个令人着迷的软件挑战。
2:30:34 The software on both, on the human software and the [inaudible 02:30:41] software.
软件既包括人类软件,也包括[听不清 02:30:41] 软件。
The organic and the inorganic.
有机和无机。
The organic and the inorganic.
有机和无机。
2:30:43 Anyway.
反正。
Sorry to rudely interrupt.
抱歉粗鲁地打扰了。
So there’s the selection that Noland has passed with flying colors.
诺兰出色地通过了这个选择。
Everything, including that it is a BCI-friendly home, all of that.
一切,包括它是一个 BCI 友好型住宅,所有这些。
So what is the process of the surgery, implantation, the first moment when he gets to use the system?
那么手术、植入、第一次使用该系统的过程是怎样的呢?
The end-to-end, we say patient end to patient out, is anywhere between two to four hours.
端到端(我们称患者端到患者出)的时间为两到四个小时。
2:31:06 In the particular case for Noland it was about three and a half hours, and there’s many steps leading to the actual robot insertion.
在诺兰的特殊情况下,大约需要三个半小时,并且有许多步骤导致实际的机器人插入。
So there’s anesthesia induction, and we do intra-op CT imaging to make sure that we’re drilling the hole in the right location.
因此,我们进行麻醉诱导,并进行术中 CT 成像,以确保我们在正确的位置钻孔。
And this is also pre-planned beforehand.
而这也是事先就计划好的。
2:31:34 Someone like Noland would go through fMRI and then they can think about wiggling their hand.
像诺兰这样的人会进行功能磁共振成像,然后他们可以考虑摆动自己的手。
Obviously due to their injury it’s not going to actually lead to any sort of intended output, but it’s the same part of the brain that actually lights up when you’re imagining moving your finger to actually moving your finger.
显然,由于他们的受伤,它实际上不会导致任何预期的输出,但当你想象移动手指和实际移动手指时,大脑的同一部分实际上会被点亮。
And that’s one of the ways in which we can actually know where to place our threads because we want to go into what’s called the hand knob area in the motor cortex.
这是我们实际上知道在哪里放置线程的方法之一,因为我们想要进入运动皮层中所谓的手柄区域。
And as much as possible, densely put our electrode threads.
并且尽可能密集地放置我们的电极线。
2:32:11 So we do intra-op CT imaging to make sure and double-check the location of the craniectomy.
因此,我们进行术中 CT 成像,以确保并仔细检查去骨瓣的位置。
And the surgeon comes in, does their thing in terms of skin incision, craniectomy, so drilling of the skull, and then there’s many different layers of the brain.
外科医生进来,做他们的工作,包括皮肤切口、颅骨切除、颅骨钻孔,然后是大脑的许多不同层。
There’s what’s called a dura, which is a very, very thick layer that surrounds the brain.
有一种叫做硬脑膜的东西,它是围绕大脑的一层非常非常厚的层。
That gets actually resected in a process called [inaudible 02:32:38].
这实际上是在一个名为 [听不清 02:32:38] 的过程中被切除的。
And that then expose the pia in the brain that you want to insert.
然后暴露你想要插入的大脑中的软脑膜。
2:32:43 And by the time it’s been around anywhere between one to one and a half hours, robot comes in, does his thing, placement of the targets, inserting of the thread.
大约一到一个半小时后,机器人就会进来,做他的事情,放置目标,插入线。
That takes anywhere between 20 to 40 minutes.
这需要 20 到 40 分钟。
In the particular case for Noland, it was just under or just over 30 minutes.
对于诺兰德来说,这个时间只有不到 30 分钟或略多于 30 分钟。
And then after that, the surgeon comes in, there’s a couple other steps of actually inserting the dural substitute layer to protect the thread as well as the brain.
之后,外科医生进来,还有其他几个步骤,实际插入硬脑膜替代层以保护线和大脑。
And then screw in the implant and then skin flap and then suture, and then you’re out.
然后拧入植入物,然后皮瓣,然后缝合,然后就可以了。
So when Noland woke up, what was that like?
那么当诺兰醒来时,那是什么样的呢?
2:33:18 What was the recovery like, and when was the first time he was able to use it?
恢复情况如何?他第一次能够使用它是什么时候?
He was actually immediately after the surgery, like an hour after the surgery, as he was waking up, we did turn on the device, make sure that we are recording neural signals.
他实际上是在手术后不久,大约手术后一个小时,当他醒来时,我们确实打开了设备,确保我们正在记录神经信号。
2:33:27 And we actually did have couple signals that we noticed that he can actually modulate.
事实上,我们确实有几个信号,我们注意到他实际上可以调节。
And what I mean by modulate is that he can think about clenching his fist and you could see the spike disappear and appear.
我所说的调节的意思是,他可以考虑握紧拳头,你可以看到尖峰消失并出现。
That’s awesome.
太棒了。
And that was immediate, immediate after in the recovery room.
那是立即的,就在康复室之后。
How cool is that?
那有多酷?
Yeah, absolutely.
是的,绝对是。
That’s a human being …
那是一个人类……
2:34:06 I mean, what did that feel like for you?
我的意思是,这对你来说是什么感觉?
This device and a human being, a first step of a gigantic journey?
这个设备和一个人,是一个巨大旅程的第一步吗?
I mean, it’s a historic moment, even just that spike, just to be able to modulate that.
我的意思是,这是一个历史性的时刻,即使只是那个峰值,只是为了能够调节它。
Obviously there have been other, as you mentioned, pioneers that have participated in these groundbreaking BCI investigational early feasibility studies.
显然,正如您提到的,还有其他先驱者参与了这些开创性的 BCI 早期可行性研究。
2:34:22 So we’re obviously standing on the shoulders of the giants here, we’re not the first ones to actually put electrodes in a human brain.
所以我们显然是站在巨人的肩膀上,我们并不是第一个真正将电极放入人脑的人。
2:34:44 But I mean, just leading up to the surgery, I definitely could not sleep.
但我的意思是,就在手术前,我绝对无法入睡。
It’s the first time that you’re working in a completely new environment.
这是您第一次在全新的环境中工作。
We had a lot of confidence based on our benchtop testing or preclinical R&D studies that the mechanism, the threads, the insertion, all that stuff is very safe and that it’s obviously ready for doing this in a human.
根据我们的台式测试或临床前研发研究,我们非常有信心,认为机制、螺纹、插入,所有这些东西都是非常安全的,而且它显然已经准备好在人类身上做到这一点。
But there’s still a lot of unknown unknown about can the needle actually insert?
但针到底能不能插入,还有很多未知的地方?
I mean, we brought something like 40 needles just in case they break, and we ended up using only one.
我的意思是,我们带了大约 40 根针,以防万一它们断裂,但最终我们只使用了一根。
But I mean, that was the level of just complete unknown because it’s a very, very different environment.
但我的意思是,那是完全未知的水平,因为这是一个非常非常不同的环境。
And I mean, that’s why we do clinical trial in the first place, to be able to test these things out.
我的意思是,这就是我们首先进行临床试验的原因,以便能够测试这些东西。
2:35:40 So extreme nervousness and just many, many sleepless night leading up to the surgery, and definitely the day before the surgery.
手术前,尤其是手术前一天,我极度紧张,无数个不眠之夜。
And it was an early morning surgery.
这是一场清晨的手术。
We started at 7:00 in the morning, and by the time it was around 10:30 everything was done.
我们早上7:00开始,到10:30左右一切都完成了。
But I mean, first time seeing that, well, number one, just huge relief that this thing is doing what it’s supposed to do.
但我的意思是,第一次看到这个,嗯,第一,这让我松了一口气,因为这东西正在做它应该做的事情。
And two, I mean, just immense amount of gratitude for Noland and his family.
我的意思是,还有两个,就是对诺兰和他的家人的巨大感激。
And then many others that have applied and that we’ve spoken to and will speak to are true pioneers in every word.
还有许多其他已经申请的、我们已经交谈过和将要交谈的人,他们在每一个词上都是真正的先驱。
And I call them the neural astronauts or neuralnaut.
我称他们为神经宇航员或神经宇航员。
Neuralnaut, yeah.
神经科学家,是的。
Just like in the ’60s, these amazing just pioneers exploring the unknown outwards, in this case it’s inward, but an incredible amount of gratitude for them to just participate and play a part.
就像 60 年代一样,这些令人惊叹的先驱者向外探索未知,在这种情况下是向内探索,但对他们参与并发挥作用感到难以置信的感激之情。
2:36:32 And it’s a journey that we’re embarking on together.
这是我们共同踏上的旅程。
2:36:57 But also, I think it was just a …
但同时,我认为这只是一个……
That was a very, very important milestone, but our work was just starting.
这是一个非常非常重要的里程碑,但我们的工作才刚刚开始。
So a lot of just anticipation for, “Okay, what needs to happen next?” What are set of sequences of events that needs to happen for us to make it worthwhile for both Noland as well as us.
所以很多人只是期待“好吧,接下来会发生什么?”我们需要发生哪些一系列事件才能让诺兰和我们都觉得值得。
Just to linger on that, just a huge congratulations to you and the team for that milestone.
在此,我衷心祝贺您和您的团队实现了这一里程碑。
2:37:17 I know there’s a lot of work left, but that’s really exciting to see.
我知道还有很多工作要做,但这真的很令人兴奋。
That’s a source of hope, it’s this first big step, opportunity, to help hundreds of thousands of people.
这是希望的源泉,这是帮助数十万人的第一步,也是机会。
And then maybe expand the realm of the possible for the human mind for millions of people in the future.
然后也许可以为未来数百万人拓展人类思维的可能性领域。
So it’s really exciting.
所以这真的很令人兴奋。
The opportunities are all ahead of us, and to do that safely and to do that effectively was really fun to see.
机会就在我们面前,安全、有效地做到这一点真的很有趣。
As an engineer, just watching other engineers come together and do an epic thing, that was awesome.
作为一名工程师,看到其他工程师聚集在一起完成一项史诗般的事情,那真是太棒了。
So huge congrats.
非常祝贺。
Thank you, thank you.
谢谢,谢谢。
2:38:03 Yeah, could not have done it without the team.
是的,没有团队就不可能做到这一点。
And yeah, I mean, that’s the other thing that I told the team as well of just this immense sense of optimism for the future.
是的,我的意思是,这也是我告诉团队的另一件事,以及对未来的巨大乐观情绪。
I mean, it’s a very important moment for the company, needless to say, as well as hopefully for many others out there that we can help.
我的意思是,不用说,这对公司来说是一个非常重要的时刻,也希望我们能够为其他许多人提供帮助。
Speaking of challenges, Neuralink published a blog post describing that some of the threads retracted.
谈到挑战,Neuralink 发表了一篇博客文章,描述了一些帖子被撤回的情况。
2:38:27 And so the performance as measured by bits per second dropped at first, but then eventually it was regained.
因此,以每秒位数衡量的性能一开始下降了,但最终又恢复了。
And the whole story of how it was regained is super interesting, that’s definitely something I’ll talk to Bliss and to Noland about.
关于它如何被重新夺回的整个故事非常有趣,这绝对是我会与布利斯和诺兰谈论的事情。
2:38:49 But in general, can you speak to this whole experience, how was the performance regained, and just the technical aspects of the threads being retracted and moving?
但总的来说,您能否谈谈整个体验,性能是如何恢复的,以及线程缩回和移动的技术方面?
The main takeaway is that in the end, the performance have come back and it’s actually gotten better than it was before.
主要的收获是,最终,性能恢复了,而且实际上比以前更好了。
2:39:03 He’s actually just beat the world record yet again last week to 8.5 bps.
事实上,他上周刚刚再次打破了世界纪录,达到 8.5 个基点。
I mean, he’s just cranking and he’s just improving.
我的意思是,他只是在起步,他只是在进步。
The previous one that he said was eight.
他说的上一个是八。
Correct.
正确的。
I think he said 8.5.
我认为他说的是8.5。
Yeah.
是的。
2:39:24 The previous world record in a human was 4.6, so it’s almost double.
之前人类的世界纪录是 4.6,所以几乎是两倍。
And his goal is to try to get to 10, which is roughly around the median neural linker using a mouse with a hand.
他的目标是尝试达到 10,这大约是使用鼠标和手的神经链接器的中位数。
So it’s getting there.
所以它已经到了那里。
So yeah, so the performance was regained.
是的,所以性能又恢复了。
Yeah, better than before.
是的,比以前好多了。
2:39:45 That’s a story on its own of what took the BCI team to recover that performance.
这本身就是 BCI 团队恢复这种表现的故事。
It was actually mostly on the signal processing.
实际上主要是关于信号处理。
And so as I mentioned, we were looking at these spike outputs from our electrodes, and what happened is that four weeks into the surgery we noticed that the threads have solely come out of the brain.
正如我所提到的,我们正在观察电极的这些尖峰输出,结果是,在手术四个星期后,我们注意到这些线仅从大脑中出来。
And the way in which we noticed this at first obviously is that, well, I think Noland was the first to notice, that his performance was degrading.
我们一开始注意到这一点的方式显然是,嗯,我认为诺兰是第一个注意到他的表现正在下降的人。
And I think at the time we were also trying to do a bunch of different experimentation, different algorithms, different UI, UX.
我想当时我们也在尝试做一些不同的实验、不同的算法、不同的用户界面、用户体验。
So it was expected that there will be variability in the performance, but we did see a steady decline.
因此,预计性能会出现波动,但我们确实看到了稳步下降。
2:40:41 And then also the way in which we measure the health of the electrodes or whether they’re in the brain or not, is by measuring impedance of the electrode.
然后,我们测量电极的健康状况或它们是否在大脑中的方法是通过测量电极的阻抗。
So we look at the interfacial, the Randles circuit they say, the capacitance and the resistance between the electrode surface and the medium.
所以我们看看界面,他们说的兰德尔斯电路,电极表面和介质之间的电容和电阻。
And if that changes in some dramatic ways, we have some indication.
如果这种情况发生一些戏剧性的变化,我们就有一些迹象。
Or if you’re not seeing spikes on those channels, you have some indications that something’s happening there.
或者,如果您没有在这些通道上看到峰值,则有一些迹象表明那里正在发生某些事情。
2:41:11 And what we noticed is that looking at those impedance plot and spike rate plots, and also because we have those electrodes recording along the depth, you are seeing some sort of movement that indicated that threads were being pulled out.
我们注意到的是,查看那些阻抗图和尖峰率图,而且因为我们有沿着深度记录的电极,您会看到某种表明线被拉出的运动。
And that obviously will have an implication on the model side because if the number of inputs that are going into the model is changing because you have less of them, that model needs to get updated.
这显然会对模型方面产生影响,因为如果进入模型的输入数量由于输入数量减少而发生变化,则该模型需要更新。
2:41:42 But there were still signals, and as I mentioned, similar to how even when you place the signals on the surface of the brain or farther away, like outside the skull, you still see some useful signals.
但仍然存在信号,正如我提到的,类似于即使将信号放置在大脑表面或更远的地方(例如头骨外部),您仍然会看到一些有用的信号。
What we started looking at is not just the spike occurrence through this BOSS algorithm that I mentioned, but we started looking at just the power of the frequency band that is interesting for Noland to be able to modulate.
我们开始关注的不仅仅是我提到的 BOSS 算法中尖峰的出现,而是我们开始关注 Noland 感兴趣的能够调制的频段的功率。
Once we changed the algorithm for the implant to not just give you the BOSS output, but also these spike band power output, that helped us refine the model with a new set of inputs.
一旦我们改变了植入物的算法,不仅为您提供了 BOSS 输出,还提供了这些尖峰带功率输出,这帮助我们使用一组新的输入来完善模型。
And that was the thing that really ultimately gave us the performance back.
这才是真正最终让我们恢复了性能的东西。
And obviously the thing that we want ultimately and the thing that we are working towards, is figuring out ways in which we can keep those threads intact for as long as possible so that we have many more channels going into the model.
显然,我们最终想要的和我们正在努力的事情是找到尽可能长时间保持这些线程完整的方法,以便我们有更多的通道进入模型。
That’s by far the number one priority that the team is currently embarking on to understand how to prevent that from happening.
到目前为止,这是该团队目前正在着手了解如何防止这种情况发生的首要任务。
2:42:56 The thing that I will say also is that, as I mentioned, this is the first time ever that we’re putting these threads in the human brain.
我还要说的是,正如我所提到的,这是我们第一次将这些线程放入人脑中。
And a human brain, just for size reference, is 10 times that of the monkey brain or the sheep brain.
而人脑,仅作为大小参考,是猴脑或羊脑的 10 倍。
And it’s just a very, very different environment.
这只是一个非常非常不同的环境。
It moves a lot more.
它移动得更多。
It’s actually moved a lot more than we expected when we did Noland’s surgery.
事实上,当我们为诺兰做手术时,它的移动量比我们预期的要大得多。
And it’s just a very, very different environment than what we’re used to.
这与我们习惯的环境非常非常不同。
And this is why we do clinical trial, we want to uncover some of these issues and failure modes earlier than later.
这就是我们进行临床试验的原因,我们希望尽早发现其中一些问题和失败模式。
2:43:37 So in many ways, it’s provided us with this enormous amount of data and information to be able to solve this.
因此,在很多方面,它为我们提供了大量的数据和信息来解决这个问题。
And this is something that Neuralink is extremely good at, once we have set of clear objective and engineering problem, we have enormous amount of talents across many, many disciplines to be able to come together and fix the problem very, very quickly.
这是 Neuralink 非常擅长的事情,一旦我们设定了明确的目标和工程问题,我们就拥有跨许多学科的大量人才,能够非常非常快地聚集在一起并解决问题。
But it sounds like one of the fascinating challenges here is for the system on the decoding side to be adaptable across different timescales.
但听起来这里令人着迷的挑战之一是解码端的系统能够适应不同的时间尺度。
2:44:01 So whether it’s movement of threads or different aspects of signal drift, sort of on the software or the human brain, something changing, like Noland talks about cursor drift, they could be corrected.
因此,无论是线程的移动还是信号漂移的不同方面,例如软件或人脑,某些变化,例如诺兰谈论光标漂移,它们都可以得到纠正。
And there’s a whole UX challenge to how to do that.
如何做到这一点是一个完整的用户体验挑战。
So it sounds like adaptability is a fundamental property that has to be engineered in.
因此,听起来适应性是一项必须加以设计的基本属性。
It is.
是的。
2:44:34 I mean, as a company, we’re extremely vertically integrated.
我的意思是,作为一家公司,我们是高度垂直整合的。
We make these thin-film arrays in our own microfab.
我们在自己的微型工厂中制造这些薄膜阵列。
Yeah, there’s like you said, built in-house.
是的,就像你说的,内部构建的。
2:44:45 This whole paragraph here from this blog post is pretty gangster.
这篇博文中的这整段都是相当黑帮的。
2:44:50 “Building the technologies described above has been no small feat,” and there’s a bunch of links here that I recommend people click on.
“构建上述技术并不是一件小事,”这里有很多链接我建议人们点击。
“We constructed in-house microfabrication capabilities to rapidly produce various iterations of thin-film arrays that constitute our electrode threads.
“我们建立了内部微加工能力,可以快速生产构成我们电极线的各种薄膜阵列迭代。
We created a custom femtosecond laser mill-“
我们创建了一个定制的飞秒激光铣床-“
[inaudible 02:45:13].
[听不清 02:45:13]。
“…
“……
2:45:12 to manufacture components with micro level precision.” I think there’s a tweet associated with this.
制造具有微米级精度的组件。”我认为有一条与此相关的推文。
That’s a whole thing that we can get into.
这是我们可以深入探讨的一件事。
Yeah.
是的。
2:45:18 Okay.
好的。
What are we looking at here, this thing?
我们在这里看什么,这个东西?
“In less than one minute, our custom-made femtosecond laser mill cuts this geometry in the tips of our needles.” So we’re looking at this weirdly shaped needle.
“不到一分钟,我们定制的飞秒激光铣刀就在我们的针尖上切割出了这种几何形状。”所以我们正在研究这种形状奇怪的针。
“The tip is only 10 to 12 microns in width, only slightly larger than the diameter of a red blood cell.
“尖端的宽度只有 10 到 12 微米,仅比红细胞的直径稍大。
The small size allows threads to be inserted with minimal damage to the cortex.”
小尺寸允许插入螺纹,同时对皮质的损伤最小。”
2:45:48 Okay.
好的。
So what’s interesting about this geometry?
那么这个几何图形有什么有趣的地方呢?
So we’re looking at this just geometry of a needle.
所以我们正在研究针的几何形状。
This is the needle that’s engaging with the loops in the thread.
这是与线环啮合的针。
2:45:53 They’re the ones that thread their loop, and then peel it from the silicon backing, and then this is the thing that gets inserted into the tissue.
它们将线圈穿入其中,然后将其从硅背衬上剥离,然后将其插入组织中。
And then this pulls out, leaving the thread.
然后将其拉出,留下线。
And this kind of a notch or the shark tooth that we used to call, is the thing that actually is grasping the loop.
这种凹口或我们以前所说的鲨鱼齿,实际上就是抓住环的东西。
And then it’s designed in such a way such that when you pull out, it leaves the loop.
然后它的设计方式是,当你拉出时,它就会离开循环。
And the robot is controlling this needle?
机器人正在控制这根针?
Correct.
正确的。
2:46:31 So this is actually housed in a cannula, and basically the robot has a lot of the optics that look for where the loop is.
所以它实际上被安置在一个插管中,基本上机器人有很多光学器件来寻找环路的位置。
There’s actually a 405 nanometer light that actually causes the polyimide to fluoresce so that you can locate the location of the loop.
实际上,405 纳米的光会使聚酰亚胺发出荧光,这样您就可以找到环路的位置。
So the loop lights up, is [inaudible 02:46:50]?”
所以循环亮了,是[听不清02:46:50]吗?”
Yeah, yeah, they do.
是的,是的,他们确实如此。
2:46:50 It’s a micron precision process.
这是一个微米级的精密工艺。
What’s interesting about the robot that it takes to do that, that’s pretty crazy.
机器人的有趣之处在于,它需要做到这一点,这非常疯狂。
2:46:54 That’s pretty crazy that robot is able to get this kind of precision.
机器人能够达到这种精度真是太疯狂了。
Yeah, our robot is quite heavy, our current version of it.
是的,我们当前版本的机器人相当重。
2:47:01 I mean, it’s like a giant granite slab that weighs about a ton, because it needs to be sensitive to vibration, environmental vibration.
我的意思是,它就像一块重约一吨的巨型花岗岩板,因为它需要对振动、环境振动敏感。
And then as the head is moving at the speed that it’s moving, there’s a lot of motion control to make sure that you can achieve that level of precision.
然后,当头部以其移动的速度移动时,需要进行大量的运动控制来确保您能够达到这种精度水平。
A lot of optics that zoom in on that.
很多光学器件都放大了这一点。
We’re working on next generation of the robot that is lighter, easier to transport.
我们正在研发更轻、更易于运输的下一代机器人。
I mean, it is a feat to move the robot to the surgical suite.
我的意思是,将机器人移至手术室是一项壮举。
And it’s far superior to a human surgeon at this time, for this particular task.
对于这项特殊任务,它目前远远优于人类外科医生。
Absolutely.
绝对的。
2:47:42 I mean, let alone you try to actually thread a loop in a sewing kit.
我的意思是,更不用说你尝试在缝纫工具中实际穿一个环了。
We’re talking fractions of human error.
我们谈论的是人为错误的一小部分。
These things, it’s not visible.
这些东西,是看不见的。
So continuing the paragraph.
所以继续这段。
2:47:54 “We developed novel hardware and software testing systems, such as our accelerated lifetime testing racks and simulated surgery environment,” which is pretty cool, “to stress test and validate the robustness of our technologies.
“我们开发了新颖的硬件和软件测试系统,例如我们的加速寿命测试架和模拟手术环境,”这非常酷,“用于压力测试和验证我们技术的稳健性。
We performed many rehearsals of our surgeries to refine our procedures and make them second nature.” This is pretty cool.
我们对手术进行了多次排练,以完善我们的手术程序并使其成为第二天性。”这很酷。
2:48:14 “We practice surgeries on proxies with all the hardware and instruments needed in our mock or in the engineering space.
“我们使用模拟或工程领域所需的所有硬件和仪器在代理上进行手术练习。
This helps us rapidly test and measure.” So there’s like proxies?
这有助于我们快速测试和测量。”那么有类似的代理吗?
Yeah, this proxy is super cool actually.
是的,这个代理实际上非常酷。
2:48:25 There’s a 3D printed skull from the images that is taken at [inaudible 02:48:34], as well as this hydrogel mix synthetic polymer thing that actually mimics the mechanical properties of the brain.
图像中有一个 3D 打印的头骨,拍摄时间为 [听不清 02:48:34],还有这种水凝胶混合合成聚合物,实际上模仿了大脑的机械特性。
It also has vasculature of the person.
它还具有人的脉管系统。
2:48:50 Basically what we’re talking about here, and there’s a lot of work that has gone into making this set proxy, that it’s about finding the right concentration of these different synthetic polymers to get the right set of consistency for the needle dynamics as they’re being inserted.
基本上我们在这里讨论的是,制作这套代理已经做了很多工作,它是为了找到这些不同合成聚合物的正确浓度,以便在插入针时获得正确的针动力学一致性。
But we practice this surgery with Noland’s basically physiology and brain many, many times prior to actually doing the surgery.
但在实际进行手术之前,我们已经根据诺兰的基本生理学和大脑进行了很多次手术练习。
Every step, every step, every-
每一步,每一步,每一个——
Every step.
每一步。
2:49:23 Yeah.
是的。
Like where does someone stand?
比如有人站在哪里?
I mean, what you’re looking at is the picture, this is in our office, of this corner of the robot engineering space that we have created this mock OR space that looks exactly like what they would experience, all the staff would during their actual surgery.
我的意思是,你看到的是图片,这是在我们的办公室,机器人工程空间的这个角落,我们创建了这个模拟手术空间,看起来与所有工作人员在实际手术中所经历的一模一样。
2:49:43 I mean, it’s just like any dance rehearsal where exactly where you’re going to stand at what point, and you just practice that over and over and over again with an exact anatomy of someone that you’re going to surgerize.
我的意思是,这就像任何舞蹈排练一样,你要准确地站在什么位置,你只需一遍又一遍地练习,并根据你要进行手术的人的精确解剖结构进行练习。
And it got to a point where a lot of our engineers, when we created a craniectomy, they’re like, “Oh, that looks very familiar.
当我们创建颅骨切除术时,我们的很多工程师都会说,“哦,这看起来很熟悉。
We’ve seen that before.”
我们以前见过这样的情况。”
Yeah.
是的。
2:50:04 Man, there’s wisdom you can gain through doing the same thing over and over and over.
伙计,通过一遍又一遍地做同样的事情,你可以获得智慧。
It’s like Jiro Dreams of Sushi kind of thing because then …
这就像寿司之二郎之梦之类的事情,因为然后……
It’s like Olympic athletes visualize the Olympics and then once you actually show up, it feels easy.
这就像奥运会运动员想象奥运会一样,然后一旦你真正出现,感觉很容易。
It feels like any other day.
感觉就像其他任何一天一样。
It feels almost boring winning the gold medal, because you visualized this so many times, you’ve practiced this so many times, that nothing about it is new.
赢得金牌感觉几乎很无聊,因为你想象了很多次,你已经练习了很多次,所以没有什么新鲜的。
It’s boring.
很无聊。
You win the gold medal, it’s boring.
你赢得了金牌,这很无聊。
And the experience they talk about is mostly just relief, probably that they don’t have to visualize it anymore.
他们谈论的经历大多只是一种解脱,可能他们不必再想象它了。
Yeah, the power of the mind to visualize and where …
是的,心灵的想象能力以及在哪里……
2:50:44 I mean, there’s a whole field that studies where muscle memory lies in cerebellum.
我的意思是,有一整个领域正在研究小脑中肌肉记忆的位置。
Yeah, it’s incredible.
是的,这太不可思议了。
I think it’s a good place to actually ask the big question that people might have, is how do we know every aspect of this that you described is safe?
我认为这是一个真正提出人们可能会提出的大问题的好地方,我们如何知道您所描述的每个方面都是安全的?
At the end of the day, the gold standard is to look at the tissue.
归根结底,黄金标准是查看组织。
2:51:06 What sort of trauma did you cause the tissue, and does that correlate to whatever behavioral anomalies that you may have seen?
您对组织造成了什么样的创伤?这是否与您可能看到的任何行为异常相关?
And that’s the language to which we can communicate about the safety of inserting something into the brain and what type of trauma that you can cause.
这就是我们可以用来传达有关将某些东西插入大脑的安全性以及可能造成的创伤类型的语言。
2:51:29 We actually have an entire department, department of pathology, that looks at these tissue slices.
我们实际上有一个完整的部门,病理学部门,负责检查这些组织切片。
There are many steps that are involved in doing this.
执行此操作涉及许多步骤。
Once you have studies that are launched with particular endpoints in mind, at some point you have to euthanize the animal, and then you go through necropsy to collect the brain tissue samples.
一旦你开始考虑特定终点的研究,在某些时候你必须对动物实施安乐死,然后进行尸检以收集脑组织样本。
You fix them in formalin, and you gross them, you section them, and you look at individual slices just to see what kind of reaction or lack thereof exists.
你将它们固定在福尔马林中,然后将它们切开,将它们切片,然后观察各个切片,看看存在什么样的反应或缺乏反应。
2:52:04 So that’s the language to which FDA speaks and as well for us to evaluate the safety of the insertion mechanism, as well as the threats at various different time points, both acute, so anywhere between zero to three months to beyond three months.
这就是 FDA 所说的语言,也是我们评估插入机制的安全性以及不同不同时间点的威胁的语言,这些威胁都是严重的,所以在零到三个月到三个月以上的任何时间点。
So those are the details of an extremely high standard of safety that has to be reached.
这些都是必须达到的极高安全标准的细节。
Correct.
正确。
The FDA supervises this, but there’s in general just a very high standard, in every aspect of this, including the surgery.
FDA 对此进行监督,但总的来说,在这方面的各个方面(包括手术)都有非常高的标准。
2:52:32 I think Matthew MacDougall has mentioned that the standard is, let’s say how to put it politely, higher than maybe some other operations that we take for granted.
我认为马修·麦克杜格尔(Matthew MacDougall)提到过,让我们礼貌地说,该标准比我们认为理所当然的其他一些操作要高。
So the standard for all the surgical stuff here is extremely high.
所以这里所有外科手术的标准都非常高。
Very high.
非常高。
2:52:57 I mean, it’s a highly, highly regulated environment with the governing agencies that scrutinize every, every medical device that gets marketed.
我的意思是,这是一个高度监管的环境,管理机构会审查每一个上市的医疗设备。
And I think it’s a good thing.
我认为这是一件好事。
It’s good to have those high standards, and we try to hold extremely high standards to understand what sort of damage, if any, these innovative emerging technologies and new technologies that we’re building are.
拥有这些高标准是件好事,我们尝试保持极高的标准来了解我们正在构建的这些创新性新兴技术和新技术会造成什么样的损害(如果有的话)。
And so far we have been extremely impressed by lack of immune response from these threads.
到目前为止,我们对这些线程缺乏免疫反应印象深刻。
Speaking of which, you talked to me with excitement about the histology in some of the images that you’re able to share.
说到这里,您兴奋地与我谈论了您能够分享的一些图像中的组织学。
2:53:34 Can you explain to me what we’re looking at?
你能向我解释一下我们在看什么吗?
Yeah, so what you’re looking at is a stained tissue image.
是的,所以你看到的是染色的组织图像。
2:53:46 This is a sectioned tissue slice from an animal that was implanted for seven months, so a chronic time point.
这是来自植入七个月的动物的组织切片,因此是一个慢性时间点。
And you’re seeing all these different colors, and each color indicates specific types of cell types.
你会看到所有这些不同的颜色,每种颜色表示特定类型的细胞类型。
So purple and pink are astrocytes and microglia, respectably.
因此,紫色和粉色分别是星形胶质细胞和小胶质细胞。
They’re types of glial cells.
它们是神经胶质细胞的类型。
2:54:12 And the other thing that people may not be aware of is your brain is not just made up of soup of neurons and axons.
人们可能没有意识到的另一件事是,你的大脑不仅仅是由神经元和轴突组成的。
There are other cells, like glial cells, that actually is the glue and also react if there are any trauma or damage to the tissue.
还有其他细胞,例如神经胶质细胞,实际上是胶水,如果组织有任何创伤或损坏,它们也会发生反应。
With the brown or the neurons here?
是棕色的还是神经元?
The brown are the neurons and the blue is nuclei.
棕色是神经元,蓝色是细胞核。
It’s a lot of neurons.
有很多神经元。
The neuro nucle.
神经核。
So what you’re seeing is in this macro image, you’re seeing these circle highlighted in white, the insertion sites.
所以你在这张宏观图像中看到的是,你看到这些圆圈以白色突出显示,即插入位点。
2:54:36 And when you zoom into one of those, you see the threads.
当你放大其中之一时,你会看到线索。
And then in this particular case, I think we’re seeing about the 16 wires that are going into the [inaudible 02:54:56].
然后在这个特殊情况下,我认为我们看到了进入 [听不清 02:54:56] 的 16 根电线。
And the incredible thing here is the fact that you have the neurons that are these brown structures or brown circular or elliptical thing-
令人难以置信的是,你的神经元是这些棕色结构或棕色圆形或椭圆形的东西——
…
……
2:55:00 are these brown structures or brown circular or elliptical thing that are actually touching and abutting the threads.
这些棕色结构或棕色圆形或椭圆形物体实际上接触并邻接螺纹。
So what this is saying is that there’s basically zero trauma that’s caused during this insertion.
所以这意味着插入过程中造成的创伤基本上为零。
And with these neural interfaces, these micro electrons that you insert, that is one of the most common mode of failure.
对于这些神经接口,您插入的这些微电子,这是最常见的故障模式之一。
So when you insert these threads like the Utah Array, it causes neuronal death around the site because you’re inserting a foreign object.
因此,当您像犹他阵列一样插入这些线时,它会导致该部位周围的神经元死亡,因为您插入了异物。
2:55:29 And that elicit these immune response through microglia and astrocytes, they form this protective layer around it.
通过小胶质细胞和星形胶质细胞引发这些免疫反应,它们在其周围形成保护层。
Oh, not only are you killing the neuron cells, but you’re also creating this protective layer that then basically prevents you from recording neural signals because you’re getting further and further away from the neurons that you’re trying to record.
哦,你不仅杀死了神经元细胞,而且还创建了这个保护层,它基本上阻止你记录神经信号,因为你离你想要记录的神经元越来越远。
And that is the biggest mode of failure.
这是最大的失败模式。
And in this particular example, in that inside it’s about 50 micron with that scale bar, the neurons seem to be attracted to it.
在这个特殊的例子中,在那个比例尺大约 50 微米的内部,神经元似乎被它吸引。
And so there’s certainly no trauma.
所以肯定没有外伤。
2:55:59 That’s such a beautiful image, by the way.
顺便说一句,这真是一个美丽的形象。
So the brown at the neurons, and for some reason I can’t look away.
因此,神经元处呈棕色,出于某种原因,我无法将目光移开。
It’s really cool.
真的很酷。
Yeah.
是的。
2:56:08 And the way that these things…
这些东西的方式……
Tissues generally don’t have these beautiful colors.
纸巾通常没有这些美丽的颜色。
This is multiplex stain that uses these different proteins that are staining these at different colors.
这是一种多重染色,使用这些不同的蛋白质将它们染色成不同的颜色。
We use very standard set of staining techniques with H&E, EVA1 and NeuN and GFAB.
我们使用非常标准的 H&E、EVA1、NeuN 和 GFAB 染色技术。
So if you go to the next image, this is also kind of illustrates the second point because you can make an argument, and initially when we saw the previous image, we said, “Oh, are the threads just floating?
所以如果你看下一张图片,这也说明了第二点,因为你可以提出一个论点,最初当我们看到上一张图片时,我们说,“哦,线程只是浮动的吗?
What is happening here?
这里发生了什么?
Are we actually looking at the right thing?” So what we did is we did another stain, and this is all done in-house of this Masson’s tricrome stain, which is in blue that shows these collagen layer.
我们真的在寻找正确的东西吗?”所以我们所做的是我们做了另一种染色,这一切都是在 Masson 的 tricrome 染色剂内部完成的,它是蓝色的,显示了这些胶原蛋白层。
So the blue, basically, you don’t want the blue around the implant threads.
所以蓝色,基本上,你不希望种植体螺纹周围有蓝色。
Because that means that there’s some sort of scarring that’s happened.
因为这意味着已经发生了某种疤痕。
And what you’re seeing if you look at individual threads is that you don’t see any of the blue.
如果你查看各个线程,你会发现你看不到任何蓝色。
Which means that there has been absolutely, or very, very minimal to a point where it’s not detectable amount of trauma in these inserted threads.
这意味着这些插入的螺纹中绝对存在或非常非常小的创伤,以至于无法检测到创伤的程度。
So that presumably is one of the big benefits of having this kind of flexible thread?
那么这大概是拥有这种灵活线程的一大好处吧?
2:57:16 This-
这——
Yeah.
是的。
2:57:21 So we think this is primarily due to the size as well as the flexibility of the threads.
所以我们认为这主要是由于线程的尺寸和灵活性。
Also, the fact that R1 is avoiding vasculature, so we’re not disrupting or we’re not causing damage to the vessels and not breaking any of the blood brain barrier, has basically caused the immune response to be muted.
此外,事实上 R1 正在避开脉管系统,因此我们不会扰乱或对血管造成损害,也不会破坏任何血脑屏障,这基本上导致了免疫反应的减弱。
But this is also a nice illustration of the size of things.
但这也是事物规模的一个很好的例证。
2:57:45 So this is the tip of the thread?
那么这就是线的尖端吗?
Yeah, those are neurons.
是的,那些是神经元。
And they’re neurons.
它们是神经元。
2:57:53 And this is the thread listening.
这是线程监听。
And the electrodes are positioned how?
电极是如何定位的?
Yeah.
是的。
2:57:59 So what you’re looking at is not electrode themselves, those are the conductive wires.
所以你看到的不是电极本身,而是导线。
So each of those should probably be two micron in width.
所以每个宽度可能应该是两微米。
So what we’re looking at is, we’re looking at the coronal slice, so we’re looking at some slice of the tissue.
所以我们正在看的是,我们正在看冠状切片,所以我们正在看一些组织切片。
So as you go deeper, you’ll obviously have less and less of the tapering of the thread.
因此,随着深入,螺纹的锥度显然会越来越少。
But yeah, the point basically being that there’s just cells around the inserter site, which is just an incredible thing to see.
但是,是的,重点是插入器部位周围只有细胞,这是令人难以置信的事情。
I’ve just never seen anything like this.
我从来没有见过这样的事情。
How easy and safe is it to remove the implant?
移除植入物有多容易和安全?
Yeah, so it depends on when.
是的,所以这取决于什么时候。
2:58:37 In the first three months or so after the surgery, there’s a lot of tissue modeling that’s happening.
在手术后的前三个月左右,需要进行大量的组织建模。
Similar to when you got a cut, you obviously start over first couple of weeks or depending on the size of the wound, scar tissue forming, there are these contractive, and then in the end they turn into scab and you can scab it off.
与割伤类似,你显然会在最初几周开始,或者根据伤口的大小、疤痕组织的形成,这些会收缩,最后它们会结痂,你可以把它结痂。
The same thing happens in the brain.
同样的事情也发生在大脑中。
And it’s a very dynamic environment.
这是一个非常充满活力的环境。
And before the scar tissue or the neo membrane or the new membrane that forms, it’s quite easy to just pull them out.
在疤痕组织或新膜或新膜形成之前,很容易将它们拔出。
And there’s minimal trauma that’s caused during that.
在此期间造成的创伤很小。
2:59:22 Once the scar tissue forms, and with Noland as well, we believe that that’s the thing that’s currently anchoring the threats.
一旦疤痕组织形成,诺兰也是如此,我们相信这就是当前威胁的根源。
So we haven’t seen any more movements since then.
所以从那以后我们就没有看到更多的动静了。
So they’re quite stable.
所以他们的表现还是很稳定的。
It gets harder to actually completely extract the threads.
真正完全提取线程变得更加困难。
So our current method for removing the device is cutting the thread, leaving the tissue intact, and then unscrewing and taking the implant out.
因此,我们目前移除装置的方法是切断螺纹,保持组织完好无损,然后拧开螺钉并取出植入物。
And that hole is now going to be plugged with either another Neuralink or just with a peak based, plastic based cap.
现在,这个洞将用另一个 Neuralink 或仅用基于峰的塑料盖来堵塞。
Is it okay to leave the threads in there forever?
可以把线永远留在那里吗?
Yeah, we think so.
是的,我们这么认为。
3:00:09 We’ve done studies where we left them there and one of the biggest concerns that we had is, do they migrate and do they get to a point where they should not be?
我们对把它们留在那里进行了研究,我们最大的担忧之一是,它们是否会迁移,是否会达到不应该的程度?
We haven’t seen that.
我们还没有看到这一点。
Again.
再次。
Once the scar tissue forms, they get anchored in place.
一旦疤痕组织形成,它们就会固定到位。
And I should also say that when we say upgrades, we’re not just talking in theory here, we’ve actually upgraded many, many times.
我还应该说,当我们说升级时,我们不仅仅是在理论上谈论,我们实际上已经升级了很多很多次。
Most of our monkeys or non-human primates, NHP, have been upgraded.
我们大多数的猴子或非人类灵长类动物 NHP 都已升级。
Pager, who you saw playing mind pong has the latest version of the device since two years ago and is seemingly very happy and healthy and fat.
你看到的佩格在玩智力乒乓球,他从两年前就开始使用最新版本的设备,看起来非常快乐、健康、肥胖。
So what’s designed for the future, the upgrade procedure?
那么,升级程序是为未来设计的什么呢?
3:00:51 So maybe for Noland, what would the upgrade look like?
那么对于诺兰来说,升级会是什么样子呢?
It was essentially what you’re mentioning.
这本质上就是你提到的。
Is there a way to upgrade the device internally where you take it apart and keep the capsule and upgrade the internals?
有没有办法在内部升级设备,将其拆开并保留胶囊并升级内部结构?
So there are a couple of different things here.
所以这里有一些不同的事情。
3:01:15 So for Noland, if we were to upgrade, what we would have to do is either cut the threads or extract the threads depending on the situation there in terms of how they’re anchored or scarred in.
因此,对于诺兰德来说,如果我们要升级,我们要做的就是切断螺纹或提取螺纹,具体取决于螺纹的固定方式或伤痕程度。
If you were to remove them with the dual substitute, you have an intact brain, so you can reinsert different threads with the updated implant package.
如果您使用双重替代品移除它们,您的大脑就会完好无损,因此您可以使用更新的植入物包重新插入不同的螺纹。
There are a couple of different other ways that we’re thinking about the future of what the upgradable system looks like.
我们还有几种不同的方式来思考可升级系统的未来。
One is, at the moment we currently remove the dura, this kind of thick layer that protects the brain, but that actually is the thing that actually proliferates the scar tissue formation.
一是,目前我们去除了硬脑膜,这种保护大脑的厚层,但实际上它实际上是促进疤痕组织形成的东西。
So typically, the general rule of thumb is you want to leave the nature as is and not disrupt it as much.
因此,一般来说,一般的经验法则是你想让自然保持原样,而不是对其造成太多破坏。
So looking at ways to insert the threats through the dura, which comes with different set of challenges such as, it’s a pretty thick layer, so how do you actually penetrate that without breaking the needle?
因此,寻找通过硬脑膜插入威胁的方法,硬脑膜会带来不同的挑战,例如,它是一个相当厚的层,那么如何在不折断针的情况下真正穿透它呢?
3:02:23 So we’re looking at different needle design for that as well as the kind of the loop engagement.
因此,我们正在研究不同的针设计以及环接合的类型。
The other biggest challenges are, it’s quite opaque, optically with white light illumination.
其他最大的挑战是,它非常不透明,在光学上采用白光照明。
So how do you avoid still this biggest advantage that we have of avoiding vasculature?
那么,如何避免我们所拥有的避免脉管系统的最大优势呢?
How do you image through that?
您对此有何看法?
How do you actually still mediate that?
你实际上仍然如何调解这个问题?
So there are other imaging techniques that we’re looking at to enable that.
因此,我们正在寻找其他成像技术来实现这一点。
But the goal, our hypothesis is that, and based on some of the early evidence that we have, doing through the dura insertion will cause minimal scarring that causes them to be much easier to extract over time.
但我们的目标是,根据我们掌握的一些早期证据,通过硬脑膜插入将产生最小的疤痕,随着时间的推移,它们会更容易被取出。
And the other thing that we’re also looking at, this is going to be a fundamental change in the implant architecture, is as at the moment, it’s a monolithic single implant that comes with a thread that’s bonded together.
我们也在关注的另一件事是,这将是植入体架构的根本性变化,就目前而言,它是一个整体式单个植入体,带有粘合在一起的螺纹。
3:03:12 So you can’t actually separate the thing out, but you can imagine having two part implant, bottom part that is the thread that are inserted that has the chips and maybe a radio and some power source.
所以你实际上无法将这个东西分开,但你可以想象有两部分植入物,底部是插入的线程,里面有芯片,也许还有无线电和一些电源。
And then you have another implant that has more of the computational heavy load and the bigger battery.
然后你就有了另一个植入物,它具有更多的计算重负载和更大的电池。
And then one can be under the dura, one can be above the dura being the plug for the skull.
然后一根可以在硬脑膜下方,一根可以在硬脑膜上方,作为头骨的塞子。
They can talk to each other, but the thing that you want to upgrade, the computer and not the thread, if you want to upgrade that, you just go in there, remove the screws, and then put in the next version.
他们可以互相交谈,但是你要升级的东西是计算机而不是线程,如果你想升级它,你只需进去,拆下螺丝,然后放入下一个版本。
And you’re off the…
而你已经离开了……
It’s a very, very easy surgery too.
这也是一个非常非常简单的手术。
You do a skin incision, slip this in, screw.
你做一个皮肤切口,把它滑进去,拧紧。
Probably be able to do this in 10 minutes.
大概10分钟之内就能完成。
So that would allow you to reuse the thread sort of?
那么这将允许您重用线程吗?
Correct.
正确的。
So I mean, this leads to the natural question of what is the pathway to scaling the increase in the number of threads?
所以我的意思是,这自然会带来一个问题:扩大线程数量的途径是什么?
3:03:59 Is that a priority?
这是优先事项吗?
What’s the technical challenge there?
其中的技术挑战是什么?
Yeah, that is a priority.
是的,这是一个优先事项。
3:04:11 So for next versions of the implant, the key metrics that we’re looking to improve are number of channels, just recording from more and more neurons.
因此,对于植入物的下一个版本,我们希望改进的关键指标是通道数量,只是记录越来越多的神经元。
We have a pathway to actually go from currently 1000 to hopefully 3000, if not 6,000 by end of this year.
我们有一条途径,到今年年底,实际上可以从目前的 1000 人增加到 3000 人,甚至 6,000 人。
Wow.
哇。
And then end of next year we want to get to even more.
到明年年底,我们希望取得更多成果。
3:04:30 16,000.
16,000。
Wow.
哇。
There’s a couple of limitations to that.
这有一些限制。
3:04:36 One is, obviously being able to photolithographically, print those wires.
一是显然能够通过光刻技术打印这些电线。
As I mentioned, it’s two micron in width and spacing.
正如我提到的,它的宽度和间距为两微米。
Obviously, there are chips that are much more advanced than those types of resolution and we have some of the tools that we have brought in house to be able to do that.
显然,有些芯片比这些类型的分辨率要先进得多,我们拥有一些内部工具来做到这一点。
So traces will be narrower just so that you have to have more of the wires coming up into the chip.
因此走线会更窄,这样你就必须有更多的电线进入芯片。
Chips also cannot linearly consume more energy as you have more and more channels.
随着通道越来越多,芯片也无法线性消耗更多能量。
So there’s a lot of innovations in the circuit, and architecture as well as the circuit design topology to make them lower power.
因此,在电路、架构以及电路设计拓扑方面有很多创新,以降低功耗。
You need to also think about if you have all of these spikes, how do you send that off to the end application.
您还需要考虑如果您有所有这些峰值,如何将其发送到最终应用程序。
So you need to think about bandwidth limitation there and potentially innovations and signal processing.
因此,您需要考虑那里的带宽限制以及潜在的创新和信号处理。
3:05:28 Physically, one of the biggest challenges is going to be the interface.
从物理上来说,最大的挑战之一是界面。
It’s always the interface that breaks bonding this thin film array to the electronics.
破坏薄膜阵列与电子器件粘合的始终是界面。
It starts to become very, very highly dense interconnects.
它开始变得非常非常密集的互连。
So how you connectivise that?
那么你如何将其连接起来呢?
There’s a lot of innovations in the 3D integrations in the recent years that we can take advantage of.
近年来,我们可以利用 3D 集成方面的许多创新。
One of the biggest challenges that we do have is forming this hermetic barrier.
我们面临的最大挑战之一就是形成这种密封屏障。
This is an extremely harsh environment that we’re in, the brain.
我们的大脑所处的环境极其恶劣。
So how do you protect it from, yeah, the brain trying to kill your electronics, to also your electronics leaking things that you don’t want into the brain.
那么,你如何保护它免受大脑试图杀死你的电子设备的影响,以及你的电子设备将你不想要的东西泄漏到大脑中的情况。
And that forming that hermetic barrier is going to be a very, very big challenge that we, I think are actually well suited to tackle.
形成这种密封屏障将是一个非常非常大的挑战,我认为我们实际上非常适合应对。
How do you test that?
你如何测试呢?
3:06:20 What’s the development environment to simulate that kind of harshness?
模拟这种严酷环境的开发环境是什么?
Yeah, so this is where the accelerated life tester essentially is a brain in a vat.
是的,这就是加速寿命测试仪本质上是缸中之脑的地方。
3:06:25 It literally is a vessel that is made up of, and again, for all intents and purpose for this particular type of test, your brain is a salt water.
从字面上看,它是一个容器,由以下部分组成,再次强调,对于这种特定类型的测试,您的大脑是盐水。
And you can also put some other set of chemicals like reactive oxygen species that get at these interfaces and trying to cause a reaction to pull it apart.
您还可以放置一些其他化学物质,例如活性氧,它们会到达这些界面并试图引起反应将其分开。
But you could also increase the rate at which these interfaces are aging by just increasing temperature.
但您也可以通过提高温度来增加这些接口的老化速度。
So every 10 degrees Celsius that you increase, you’re basically accelerating time by two X.
因此,每升高 10 摄氏度,时间基本上就会加快两倍。
3:07:11 And there’s limit as to how much temperature you want to increase because at some point there’s some other nonlinear dynamics that causes you to have other nasty gases to form that just is not realistic in an environment.
你想要增加多少温度是有限制的,因为在某些时候,还有一些其他非线性动力学会导致你形成其他令人讨厌的气体,这在环境中是不现实的。
So what we do is we increase in our ALT chamber by 20 degrees Celsius that increases the aging by four times.
因此,我们所做的就是将 ALT 室的温度提高 20 摄氏度,从而使老化速度增加四倍。
So essentially one day in ALT chamber is four day in calendar year, and we look at whether the implants still are intact, including the threats.
因此,在 ALT 室中的一天基本上是一年中的四天,我们会检查植入物是否仍然完好无损,包括威胁。
And-
还有——
And operation and all of that.
以及操作等等。
…
……
3:07:45 and operation and all of that.
和操作以及所有这些。
Obviously, is not an exact same environment as a brain because brain has mechanical other more biological groups that attack at it.
显然,这与大脑的环境并不完全相同,因为大脑有机械的其他更多的生物群体对其进行攻击。
But it is a good test environment, testing environment for at least the enclosure and the strength of the enclosure.
但它是一个很好的测试环境,至少测试外壳和外壳强度的环境。
And I mean, we’ve had implants, the current version of the implant that has been in there for close to two and a half years, which is equivalent to a decade and they seem to be fine.
我的意思是,我们已经植入了植入物,当前版本的植入物已经存在了近两年半,相当于十年,而且看起来效果很好。
So it’s interesting that basically close approximation is warm salt water, hot salt water is a good testing environment.
所以有趣的是,基本上接近的是温盐水,热盐水是一个很好的测试环境。
Yeah.
是的。
By the way, I’m drinking LMNT , which is basically salt water.
顺便说一句,我喝的是 LMNT,基本上是盐水。
3:08:29 Which is making me kind of…
这让我有点……
It doesn’t have computational power the way the brain does, but maybe in terms of other characteristics, it’s quite similar and I’m consuming it.
它没有大脑那样的计算能力,但也许在其他特征方面,它非常相似,我正在消耗它。
Yeah.
是的。
3:08:44 You have to get it in the right pH too.
你也必须让它达到正确的pH值。
And then consciousness will emerge.
然后意识就会出现。
3:08:48 Yeah, no.
是的,不。
All right.
好的。
By the way, the other thing that also is interesting about our enclosure is, if you look at our implant, it’s not your common looking medical implant that usually is encased in a titanium can that’s laser welded.
顺便说一句,我们的外壳另一件有趣的事情是,如果您观察我们的植入物,您会发现它并不是常见的医疗植入物,通常装在激光焊接的钛罐中。
3:08:52 We use this polymer called PCTFE, polychlorotrifluoroethylene, which is actually commonly used in blister packs.
我们使用这种称为 PCTFE(聚氯三氟乙烯)的聚合物,它实际上常用于泡罩包装。
So when you have a pill and you try to pop a pill, there’s kind of that plastic membrane.
所以当你有一颗药丸并试图弹出药丸时,就会有一种塑料膜。
That’s what this is.
就是这样。
No one’s actually ever used this except us.
除了我们之外,没有人真正使用过这个。
And the reason we wanted to do this is because electromagnetically transparent.
我们想要这样做的原因是因为电磁透明。
So when we talked about the electromagnetic inductive charging, with titanium can usually if you want to do something like that, you have to have a sapphire window and it’s a very, very tough process to scale.
因此,当我们谈论电磁感应充电时,如果你想做类似的事情,通常用钛可以做到这一点,你必须有一个蓝宝石窗口,这是一个非常非常难以扩展的过程。
So you’re doing a lot of iteration here in every aspect of this.
所以你在这方面的各个方面都进行了大量的迭代。
3:09:45 The materials, the software, all.
材料,软件,全部。
The whole shebang.
整个舍邦。
Okay.
好的。
3:09:53 So you mentioned scaling.
所以你提到了缩放。
Is it possible to have multiple Neuralink devices as one of the ways of scaling?
是否可以使用多个 Neuralink 设备作为扩展方式之一?
To have multiple Neuralink devices implanted?
植入多个 Neuralink 设备?
That’s the goal.
这就是目标。
3:10:08 That’s the goal.
这就是目标。
Yeah.
是的。
I mean, our monkeys have had two neural links, one in each hemisphere.
我的意思是,我们的猴子有两个神经连接,每个半球都有一个。
And then we’re also looking at potential of having one in motor cortex, one in visual cortex and one in wherever other cortex.
然后我们还在研究在运动皮层中放置一个、在视觉皮层中放置一个以及在其他皮层中放置一个的潜力。
So focusing on the particular function one Neuralink device.
因此,重点关注 Neuralink 设备的特定功能。
Correct.
正确的。
I mean, I wonder if there’s some level of customization that can be done on the compute side.
我的意思是,我想知道是否可以在计算端进行某种程度的定制。
3:10:29 So for the motor cortex-
所以对于运动皮层来说——
Absolutely.
绝对的。
3:10:34 That’s the goal.
这就是目标。
And we talk about at Neuralink building a generalized neural interface to the brain.
我们在 Neuralink 讨论构建一个通用的大脑神经接口。
And that also is strategically how we’re approaching this with marketing and also with regulatory, which is, hey, look, we have the robot and the robot can access any part of the cortex.
这也是我们在营销和监管方面采取的策略,也就是说,嘿,看,我们有机器人,机器人可以访问大脑皮层的任何部分。
Right now we’re focused on motor cortex with current version of the N1 that’s specialized for motor decoding tasks.
目前,我们专注于运动皮层,当前版本的 N1 专门用于运动解码任务。
But also at the end of the day, there’s a general compute available there.
但归根结底,那里还有可用的通用计算。
But typically if you want to really get down to hyperoptimizing for power and efficiency, you do need to get to some specialized function.
但通常情况下,如果您想真正开始对功率和效率进行超级优化,您确实需要使用一些专门的功能。
3:11:21 But what we’re saying is that, hey, you are now used to this robotic insertion techniques, which took many, many years of showing data and conversation with the FDA and also internally convincing ourselves that this is safe.
但我们想说的是,嘿,你现在已经习惯了这种机器人插入技术,它花了很多很多年的时间来展示数据并与 FDA 进行对话,并在内部说服自己这是安全的。
And now the difference is if we go to other parts of the brain, like visual cortex, which we’re interested in as our second product, obviously it’s a completely different environment, the cortex is laid out very, very differently.
现在的区别是,如果我们进入大脑的其他部分,比如视觉皮层,我们感兴趣的是作为我们的第二个产品,显然这是一个完全不同的环境,皮层的布局非常非常不同。
It’s going to be more stimulation focus rather than recording, just kind of creating visual percepts.
它将更多地集中于刺激而不是记录,只是创造视觉感知。
But in the end, we’re using the same thin film array technology, we’re using the same robot insertion technology, we’re using the same packaging technology.
但最终,我们使用相同的薄膜阵列技术,我们使用相同的机器人插入技术,我们使用相同的封装技术。
Now it’s where the conversation is focused around what are the differences and what are the implication of those differences in safety and efficacy.
现在讨论的重点是差异是什么以及这些差异对安全性和有效性的影响是什么。
The way you said second product is both hilarious and awesome to me.
你所说的第二个产品对我来说既搞笑又很棒。
3:12:17 That product being restoring sight for blind people.
该产品正在帮助盲人恢复视力。
So can you speak to stimulating the visual cortex?
那么你能谈谈刺激视觉皮层吗?
I mean, the possibilities there are just incredible to be able to give that gift back to people who don’t have sight or even any aspect of that.
我的意思是,能够将这份礼物回馈给那些没有视力甚至任何方面的人的可能性是令人难以置信的。
Can you just speak to the challenges of…
您能谈谈……的挑战吗?
There’s challenges here-
这里有挑战——
Oh many.
哦很多。
One of which is like you said, from recording to stimulation.
其中之一就像你说的,从录音到刺激。
3:12:51 Just any aspect of that that you’re both excited and see the challenges of?
您对其中的哪些方面既感到兴奋又看到挑战?
Yeah, I guess I’ll start by saying that we actually have been capable of stimulating through our thin film array as well as other electronics for years.
是的,我想我首先要说的是,多年来我们实际上已经能够通过薄膜阵列以及其他电子设备进行刺激。
3:13:02 We have actually demonstrated some of that capabilities for reanimating the limb in the spinal cord.
我们实际上已经展示了一些使脊髓中的肢体恢复活力的能力。
Obviously, for the current EFS study, we’ve hardware disabled that.
显然,对于当前的 EFS 研究,我们已通过硬件禁用了该功能。
So that’s something that we wanted to embark as a separate journey.
因此,我们希望将其作为一个单独的旅程来开始。
And obviously, there are many, many different ways to write information into the brain.
显然,有很多很多不同的方法可以将信息写入大脑。
The way in which we’re doing that is through electrical, passing electrical current, and kind of causing that to really change the local environment so that you can artificially cause the neurons to depolarize in nearby areas.
我们这样做的方式是通过电力,传递电流,并使其真正改变局部环境,这样你就可以人为地导致附近区域的神经元去极化。
For vision, specifically the way our visual system works, it’s both well understood.
对于视觉,特别是我们的视觉系统的工作方式,这是很好理解的。
I mean, anything with kind of brain, there are aspects of it that’s well understood, but in the end, we don’t really know anything.
我的意思是,任何有大脑的东西,它的某些方面都是很好理解的,但最终,我们真的一无所知。
3:14:10 But the way visual system works is that you have photon hitting your eye, and in your eyes there are these specialized cells called photoreceptor cells that convert the photon energy into electrical signals.
但视觉系统的工作方式是让光子射到你的眼睛,在你的眼睛里有这些称为感光细胞的特殊细胞,它们将光子能量转化为电信号。
And then that then gets projected to your back of your head, your visual cortex.
然后它会被投射到你的后脑勺,你的视觉皮层。
It goes through actually thalamic system called LGN that then projects it out.
它实际上通过称为 LGN 的丘脑系统,然后将其投射出去。
And then in the visual cortex there’s visual area one or V1, and then there’s a bunch of other higher level processing layers like V2, V3.
然后在视觉皮层中有视觉区域一或 V1,然后有一堆其他更高级别的处理层,如 V2、V3。
And there are actually kind of interesting parallels.
实际上有一些有趣的相似之处。
And when you study the behaviors of these convolutional neural networks, like what the different layers of the network is detecting, first they’re detecting these edges and they’re then detecting some more natural curves and then they start to detect objects.
当您研究这些卷积神经网络的行为时,例如网络的不同层正在检测的行为,它们首先检测这些边缘,然后检测一些更自然的曲线,然后开始检测对象。
3:15:08 Kind of similar thing happens in the brain.
类似的事情也发生在大脑中。
And a lot of that has been inspired and also it’s been kind of exciting to see some of the correlations there.
其中很多都受到了启发,而且看到其中的一些相关性也令人兴奋。
But things like from there, where does cognition arise and where’s color encoded?
但从那里开始,认知从哪里产生,颜色在哪里编码?
There’s just not a lot of understanding, fundamental understanding there.
只是没有太多的理解,基本的理解。
So in terms of bringing sight back to those that are blind, there are many different forms of blindness.
因此,就让盲人重见光明而言,失明有许多不同的形式。
There’s actually million people, 1 million people in the US that are legally blind.
事实上,在美国有一百万人是法定盲人。
That means certain score below in the visual tests.
这意味着视觉测试中的分数低于一定水平。
I think it’s something like if you can see something at 20 feet distance that normal people can see at 200 feet distance, if you’re worse than that, you’re legally blind.
我认为这就像如果你能在 20 英尺距离处看到正常人在 200 英尺距离处能看到的东西,如果你比这更糟糕,那么你就在法律上失明了。
So fundamental that means you can’t function effectively using sight in the world.
从根本上来说,这意味着你无法利用视觉在世界上有效地发挥作用。
Like to navigate-
喜欢导航-
To navigate.
导航。
…
……
3:16:04 you’re environment.
你是环境。
And yeah, there are different forms of blindness.
是的,失明有不同的形式。
There are forms of blindness where there’s some degeneration of your retina is photoreceptor cells and rest of your visual processing that I described is intact.
在某些形式的失明中,您的视网膜感光细胞发生了一些退化,而我所描述的其余视觉处理功能却完好无损。
And for those types of individuals, you may not need to maybe stick electrodes into the visual cortex.
对于这些类型的人,您可能不需要将电极插入视觉皮层。
You can actually build retinal prosthetic devices that actually just replaces the function of that retinal cells that are degenerated.
你实际上可以建造视网膜假体装置,它实际上只是取代退化的视网膜细胞的功能。
And there are many companies that are working on that, but that’s a very small slice albeit significance, those smaller slice of folks that are legally blind.
有很多公司正在努力解决这个问题,但尽管意义重大,但那只是一小部分,即法律上盲人的一小部分。
3:16:51 If there’s any damage along that circuitry, whether it’s in the optic nerve or just the LGN circuitry or any break in that circuit, that’s not going to work for you.
如果该电路有任何损坏,无论是视神经还是 LGN 电路,或者该电路有任何损坏,这对您都不起作用。
And the source of where you need to actually cause that visual percepts to happen because your biological mechanism not doing that is by placing electrodes in the visual cortex in the back of your head.
而你真正需要引起视觉感知发生的来源是通过在你后脑勺的视觉皮层中放置电极来实现的,因为你的生物机制没有这样做。
And the way in which this would work is that you would have an external camera, whether it’s something as unsophisticated as a GoPro or some sort of wearable Ray- Ban type glasses that meta is working on that captures a scene.
其工作方式是你拥有一个外部摄像头,无论它是像 GoPro 这样简单的东西,还是 Meta 正在开发的某种可佩戴的雷朋式眼镜来捕捉场景。
And that scene is then converted to a set of electrical impulses or stimulation pulses that you would activate in your visual cortex through these thin film arrays.
然后,该场景会转换为一组电脉冲或刺激脉冲,您可以通过这些薄膜阵列在视觉皮层中激活它们。
And by playing some a concerted kind of orchestra of these stimulation patterns, you can create what’s called phosphenes, which are these kind of white yellowish dots that you can also create by just pressing your eyes.
通过演奏这些刺激模式的协奏曲,你可以创造出所谓的光幻视,这是一种白色的黄点,你也可以通过按压你的眼睛来创造它们。
You can actually create those percepts by stimulating the visual cortex.
实际上,您可以通过刺激视觉皮层来创建这些感知。
3:18:08 And the name of the game is really have many of those and have those percepts, be the phosphenes, be as small as possible so that you can start to tell apart they’re the individual pixels of the screen.
游戏的名称确实是拥有很多这样的东西并具有这些感知,成为光幻视,尽可能小,这样你就可以开始区分它们是屏幕上的各个像素。
So if you have many, many of those potentially you’ll be able to, in the long term, be able to actually get naturalistic vision.
因此,如果你有很多很多这样的潜力,从长远来看,你将能够真正获得自然主义的视觉。
But in the short term to maybe midterm, being able to at least, be able to have object detection algorithms run on your glasses, the pre-processing units, and then being able to at least see the edges of things so you don’t bump into stuff.
但从短期到中期,至少能够在你的眼镜、预处理单元上运行物体检测算法,然后至少能够看到物体的边缘,这样你就不会撞到东西。
This is incredible.
这太不可思议了。
3:18:46 This is really incredible.
这实在是太不可思议了。
So you basically would be adding pixels and your brain would start to figure out what those pixels mean with different kinds of assistant signal processing on all fronts.
因此,您基本上会添加像素,然后您的大脑将开始弄清楚这些像素对于各个方面的不同类型的辅助信号处理意味着什么。
Yeah.
是的。
3:18:59 The thing that actually…
事情其实是……
So a couple of things.
有几件事。
One is obviously if you’re blind from birth, the way brain works, especially in the early age, neuroplasticity is really nothing other than your brain and different parts of your brain fighting for the limited territory.
一个明显的问题是,如果你从出生起就失明,那么大脑的工作方式,尤其是在早期,神经可塑性实际上只不过是你的大脑和大脑的不同部分争夺有限的领土。
And I mean very, very quickly you see cases where people that are…
我的意思是,很快你就会看到人们……
I mean, you also hear about people who are blind that have heightened sense of hearing or some other senses.
我的意思是,你也会听说盲人的听觉或其他感官有增强。
And the reason for that is because that cortex that’s not used just gets taken over by these different parts of the cortex.
其原因是因为未使用的皮层只是被皮层的这些不同部分接管。
So for those types of individuals, I mean I guess they’re going to have to now map some other parts of their senses into what they call vision, but it’s going to be obviously a very, very different conscious experience.
因此,对于这些类型的人,我的意思是,我想他们现在必须将感官的其他部分映射到他们所谓的视觉中,但这显然将是一种非常非常不同的意识体验。
3:19:54 Before…
之前……
So I think that’s an interesting caveat.
所以我认为这是一个有趣的警告。
The other thing that also is important to highlight is that, we’re currently limited by our biology in terms of the wavelength that we can see.
另一件需要强调的事情是,我们目前在可见波长方面受到生物学的限制。
There’s a very, very small wavelength that is a visible light wavelength that we can see with our eyes.
有一个非常非常小的波长,是我们用眼睛可以看到的可见光波长。
But when you have an external camera with this BCI system, you’re not limited to that.
但是,当您拥有配备此 BCI 系统的外部摄像头时,您就不受此限制。
You can have infrared, you can have UV, you can have whatever other spectrum that you want to see.
你可以有红外线,你可以有紫外线,你可以有任何你想看到的其他光谱。
And whether that gets matched to some sort of weird conscious experience, I’ve no idea.
我不知道这是否与某种奇怪的意识体验相匹配。
But oftentimes I talk to people about the goal of Neuralink being going beyond the limits of our biology.
但我经常和人们谈论 Neuralink 的目标是超越我们的生物学极限。
That’s sort of what I mean.
这就是我的意思。
And if you’re able to control the kind of raw signal, is that when we use our site, we’re getting the photons and there’s not much processing on it.
如果你能够控制原始信号的类型,那么当我们使用我们的网站时,我们就会获取光子,并且对其进行不需要太多处理。
3:20:39 If you’re being able to control that signal, maybe you can do some kind of processing, maybe you do object detection ahead of time.
如果您能够控制该信号,也许您可以进行某种处理,也许您可以提前进行对象检测。
You’re doing some kind of pre-processing and there’s a lot of possibilities to explore that.
你正在做某种预处理,并且有很多可能性可以探索。
So it’s not just increasing thermal imaging, that kind of stuff, but it’s also just doing some kind of interesting processing.
因此,它不仅仅是增加热成像之类的东西,而且还只是进行某种有趣的处理。
Correct.
正确的。
3:21:10 Yeah.
是的。
I mean, my theory of how visual system works also is that, I mean, there’s just so many things happening in the world and there’s a lot of photons that are going into your eye.
我的意思是,我关于视觉系统如何工作的理论是,世界上发生了很多事情,并且有很多光子进入你的眼睛。
And it’s unclear exactly where some of the pre-processing steps are happening.
目前还不清楚一些预处理步骤到底发生在哪里。
But I mean, I actually think that just from a fundamental perspective, there’s just so much the reality that we’re in, if it’s a reality, so there’s so much data and I think humans are just unable to actually eat enough, actually to process all that information.
但我的意思是,我实际上认为,从基本角度来看,我们所处的现实实在是太多了,如果它是现实的话,那就有太多的数据,我认为人类实际上无法吃得足够多,无法真正处理所有这些信息。
So there’s some sort of filtering that does happen, whether that happens in the retina, whether that happens in different layers of the visual cortex, unclear.
因此,确实会发生某种过滤,无论是发生在视网膜中,还是发生在视觉皮层的不同层中,尚不清楚。
But the analogy that I sometimes think about is, if your brain is a CCD camera and all of the information in the world is a sun, and when you try to actually look at the sun with the CCD camera, it’s just going to saturate the sensors because it’s an enormous amount of energy.
但我有时会想到的类比是,如果你的大脑是一个 CCD 相机,世界上所有的信息都是太阳,当你尝试用 CCD 相机实际观察太阳时,它只会使传感器饱和,因为它有巨大的能量。
3:22:16 So what you do is you end up adding these filters to just kind of narrow the information that’s coming to you and being captured.
因此,您最终要做的就是添加这些过滤器,以缩小您收到并被捕获的信息范围。
And I think things like our experiences or our drugs like propofol, anesthetics drug or psychedelics, what they’re doing is they’re kind of swapping out these filters and putting in new ones or removing older ones and kind of controlling our conscious experience.
我认为像我们的经历或我们的药物,如异丙酚、麻醉药或迷幻药,他们所做的就是更换这些过滤器并放入新的或去除旧的过滤器,并控制我们的意识体验。
Yeah, man, not to distract from the topic, but I just took a very high dose of ayahuasca in the Amazon jungle.
是的,伙计,不是为了分散注意力,但我刚刚在亚马逊丛林中服用了非常高剂量的死藤水。
3:22:50 So yes, it’s a nice way to think about it.
所以,是的,这是一个很好的思考方式。
You’re swapping out different experiences and with Neuralink being able to control that, primarily at first to improve function, not for entertainment purposes or enjoyment purposes, but-
你正在交换不同的体验,并且 Neuralink 能够控制它,首先主要是为了改进功能,而不是为了娱乐目的或享受目的,但是 -
Yeah, giving back loss functions.
是的,恢复损失函数。
Giving back loss functions.
返还损失函数。
3:23:13 And there, especially when the function is completely lost, anything is a huge help.
在那里,特别是当功能完全丧失时,任何东西都是巨大的帮助。
Would you implant a Neuralink device in your own brain?
你会在自己的大脑中植入 Neuralink 设备吗?
Absolutely.
绝对地。
3:23:29 I mean, maybe not right now, but absolutely.
我的意思是,也许不是现在,但绝对是。
What kind of capability once reached you start getting real curious and almost get a little antsy, jealous of people as you watch them get implanted?
一旦获得了什么样的能力,当你看到人们被植入时,你就会开始变得真正好奇,甚至有点坐立不安、嫉妒?
Yeah, I think even with our early participants, if they start to do things that I can’t do, which I think is in the realm of possibility for them to be able to get 15, 20 if not like a hundred BPS.
是的,我认为即使是我们的早期参与者,如果他们开始做我做不到的事情,我认为他们有可能获得 15、20 个 BPS(如果不是 100 个 BPS)。
3:23:46 There’s nothing that fundamentally stops us from being able to achieve that type of performance.
没有什么可以从根本上阻止我们实现这种性能。
I mean, I would certainly get jealous that they can do that.
我的意思是,我肯定会嫉妒他们能做到这一点。
I should say that watching Noland, I get a little jealous having so much fun, and it seems like such a chill way to play video games.
我应该说,看着诺兰,我有点嫉妒拥有如此多的乐趣,而且这似乎是一种玩电子游戏的冷静方式。
Yeah.
是的。
3:24:19 I mean the thing that also is hard to appreciate sometimes is that, he’s doing these things while talking.
我的意思是,有时也很难欣赏的是,他一边说话一边做这些事情。
And I mean, it’s multitasking, so it’s clearly, it’s obviously cognitively intensive.
我的意思是,它是多任务处理,所以很明显,它显然是认知密集型的。
But similar to how when we talk, we move our hands.
但与我们说话时移动双手的方式类似。
These are multitasking.
这些都是多任务处理。
I mean, he’s able to do that.
我的意思是,他能够做到这一点。
And you won’t be able to do that with other assistive technology.
而其他辅助技术则无法做到这一点。
As far as I am aware, if you’re obviously using an eye tracking device, you’re very much fixated on that thing that you’re trying to do.
据我所知,如果你显然正在使用眼球追踪设备,那么你就会非常专注于你正在尝试做的事情。
And if you’re using voice control, I mean if you say some other stuff, you don’t get to use that.
如果你使用语音控制,我的意思是如果你说一些其他的东西,你就不能使用它。
The multitasking aspect of that is really interesting.
多任务处理方面非常有趣。
3:25:02 So it’s not just the BPS for the primary task, it’s the parallelization of multiple tasks.
所以这不仅仅是主要任务的 BPS,而是多个任务的并行化。
If you measure the BPS for the entirety of the human organism.
如果你测量整个人体的 BPS。
So you’re talking and doing a thing with your mind and looking around also, I mean, there’s just a lot of parallelization that can be happening.
所以你用你的头脑说话和做事,同时环顾四周,我的意思是,可能会发生很多并行化。
But I mean, I think at some point for him, if he wants to really achieve those high level BPS, it does require a full attention.
但我的意思是,我认为在某些时候对他来说,如果他想真正达到那些高水平的 BPS,确实需要全神贯注。
3:25:28 And that’s a separate circuitry that is a big mystery, how attention works and…
这是一个独立的电路,是一个很大的谜团,注意力是如何运作的……
Yeah, attention, cognitive load.
是的,注意力,认知负荷。
3:25:41 I’ve read a lot of literature on people doing two tasks.
我读过很多关于人们做两项任务的文献。
You have your primary task and a secondary task, and the secondary task is a source of distraction.
你有主要任务和次要任务,次要任务是分散注意力的来源。
And how does that affect the performance of the primary task?
这对主要任务的执行有何影响?
And depending on the tasks, because there’s a lot of interesting…
取决于任务,因为有很多有趣的事情......
I mean, this is an interesting computational device, and I think there’s-
我的意思是,这是一个有趣的计算设备,我认为有-
To say the least.
至少可以说。
…
……
3:26:05 a lot of novel insights that can be gained from everything.
从一切事情中都可以获得很多新奇的见解。
I mean, I personally am surprised that no one’s able to do such incredible control of the cursor while talking.
我的意思是,我个人感到惊讶的是,没有人能够在说话时对光标进行如此令人难以置信的控制。
And also being nervous at the same time because he’s talking like all of us are if you’re talking in front of the camera, you get nervous.
同时也会感到紧张,因为他说话的方式就像我们所有人一样,如果你在镜头前说话,你就会感到紧张。
So all of those are coming into play and he’s able to still achieve high performance.
所以所有这些都在发挥作用,他仍然能够取得出色的表现。
Surprising.
奇怪。
I mean, all of this is really amazing.
我的意思是,这一切真的太棒了。
And I think just after researching this really in depth, I kind of want a Neuralink.
我想在真正深入研究之后,我有点想要一个 Neuralink。
Get in the line.
排队吧。
And also the safety get in line.
而且安全也要排队。
3:26:39 Well, we should say the registry is for people who have quadriplegia and all that kind of stuff, so.
好吧,我们应该说登记处是为四肢瘫痪之类的人服务的,所以。
Correct.
正确的。
That’d be a separate line for people.
对于人们来说,这将是一条单独的线。
3:26:47 They’re just curious like myself.
他们只是像我一样好奇。
So now that Noland, patient P1 is part of the ongoing prime study, what’s the high level vision for P2, P3, P4, P5, and just the expansion into other human beings that are getting to experience this implant?
那么,现在 Noland,患者 P1 是正在进行的主要研究的一部分,P2、P3、P4、P5 的高水平愿景是什么,以及扩展到其他正在体验这种植入的人类?
Yeah, I mean the primary goal is for our study in the first place is to achieve safety endpoints.
是的,我的意思是我们研究的主要目标首先是实现安全终点。
3:27:14 Just understand safety of this device as well as the implantation process.
只需了解该设备的安全性以及植入过程即可。
And also at the same time understand the efficacy and the impact that it could have on the potential user’s lives.
同时还要了解它的功效以及它可能对潜在用户的生活产生的影响。
And Just because you have, you’re living with tetraplegia, it doesn’t mean your situation is same as another person living with tetraplegia.
仅仅因为您患有四肢瘫痪,并不意味着您的情况与其他四肢瘫痪的人相同。
It’s wildly, wildly varying.
它变化很大。
And it’s something that we’re hoping to also understand how our technology can serve not just a very small slice of those individuals, but broader group of individuals and being able to get the feedback to just really build just the best product for them.
我们还希望了解我们的技术如何不仅能够服务于一小部分人,而且能够服务于更广泛的群体,并能够获得反馈,从而真正为他们打造最好的产品。
3:28:11 So there’s obviously, also goals that we have.
所以显然我们也有目标。
And the primary purpose of the early feasibility study is to learn from each and every participant to improve the device, improve the surgery before we embark on what’s called a pivotal study.
早期可行性研究的主要目的是在我们开始所谓的关键研究之前向每个参与者学习以改进设备、改进手术。
That then is a much larger trial that starts to look at statistical significance of your endpoints and that’s required before you can then market the device.
这是一个更大规模的试验,开始研究端点的统计显着性,这是您销售设备之前所必需的。
And that’s how it works in the US and just generally around the world.
这就是它在美国以及世界各地的运作方式。
That’s the process you follow.
这就是您遵循的流程。
3:28:50 So our goal is to really just understand from people like Noland, P2, P3, future participants, what aspects of our device needs to improve.
因此,我们的目标是真正从 Noland、P2、P3 等未来参与者那里了解我们设备的哪些方面需要改进。
If it turns out that people are like, “I really don’t like the fact that it lasts only six hours.
如果事实证明人们会说,“我真的不喜欢它只持续六个小时。
I want to be able to use this computer for 24 hours.” I mean, that is a user needs and user requirements, which we can only find out from just being able to engage with them.
我希望能够 24 小时使用这台电脑。”我的意思是,这是用户的需求和用户的要求,我们只能通过与他们接触才能找到答案。
So before the pivotal study, there’s kind of a rapid innovation based on individual experiences.
因此,在关键研究之前,需要根据个人经验进行快速创新。
3:29:17 You’re learning from individual people, how they use it, the high resolution details in terms of cursor control and signal and all that kind of stuff, life experience.
你正在向个人学习,他们如何使用它,光标控制和信号方面的高分辨率细节以及所有这些东西,生活经验。
So there’s hardware changes, but also just firmware updates.
所以有硬件变化,但也只是固件更新。
3:29:33 So even when we had that sort of recovery event for Noland, he now has the new firmware that he has been updated with, and similar to how your phones get updated all the time with new firmware for security patches, whatever, new functionality, UI.
因此,即使我们为诺兰进行了此类恢复活动,他现在也拥有了已更新的新固件,就像您的手机一直使用安全补丁的新固件进行更新一样,无论什么,新功能,用户界面。
And that’s something that is possible with our implant.
我们的植入物可以实现这一点。
It’s not a static one-time device that can only do…
它不是一个静态的一次性设备,只能做……
3:30:00 It’s not a static one-time device that can only do the thing that it said it can do.
它不是一个静态的一次性设备,只能做它所说的事情。
I mean, it’s similar to Tesla, you can do over-the-air firmware updates, and now you have completely new user interface and all these bells and whistles and improvements on everything, like the latest.
我的意思是,它与特斯拉类似,您可以进行无线固件更新,现在您拥有全新的用户界面以及所有这些附加功能和所有方面的改进,例如最新的。
Right?
正确的?
When we say generalized platform, that’s what we’re talking about.
当我们说通用平台时,这就是我们所说的。
Yeah.
是的。
3:30:22 It’s really cool how the app that Noland is using, there’s calibration, all that kind of stuff, and then there’s update.
诺兰使用的应用程序真的很酷,有校准,所有类似的东西,然后还有更新。
You just click and get an update.
您只需点击即可获取更新。
3:30:35 What other future capabilities are you looking to?
您还希望未来具备哪些其他功能?
You said vision.
你说的是愿景。
That’s a fascinating one.
这是一件令人着迷的事。
What about accelerated typing or speech, or this kind of stuff?
加速打字或语音或类似的东西怎么样?
And what else is there?
还有什么?
Yeah.
是的。
3:30:49 Those are still in the realm of movement program.
这些仍然属于运动程序的范围。
So, largely speaking, we have two programs.
所以,总的来说,我们有两个计划。
We have the movement program and we have the vision program.
我们有运动计划,也有愿景计划。
The movement program currently is focused around the digital freedom.
目前,该运动计划的重点是数字自由。
As you can easily guess, if you can control 2D cursor in the digital space, you could move anything in the physical space.
您很容易猜到,如果您可以在数字空间中控制 2D 光标,那么您就可以在物理空间中移动任何东西。
So, robotic arms, wheelchair, your environment, or even really, whether it’s through the phone or just directly to those interfaces, to those machines.
所以,机械臂、轮椅、你的环境,甚至是真的,无论是通过电话还是直接连接到那些接口、那些机器。
3:31:22 So, we’re looking at ways to expand those types of capability, even for Noland.
因此,我们正在寻找扩展这些类型能力的方法,即使是诺兰德也是如此。
That requires conversation with the FDA and showing safety data for if there’s a robotic arm or a wheelchair, that we can guarantee that they’re not going to hurt themselves accidentally.
这需要与 FDA 进行对话,并提供有关是否有机械臂或轮椅的安全数据,以便我们可以保证它们不会意外伤害自己。
Right?
正确的?
It’s very different if you’re moving stuff in the digital domain versus in the physical space, you can actually potentially cause harm to the participants.
如果你在数字领域和物理空间中移动东西,情况就非常不同,你实际上可能会对参与者造成伤害。
So, we’re working through that right now.
所以,我们现在正在解决这个问题。
3:31:50 Speech does involve different areas of the brain.
言语确实涉及大脑的不同区域。
Speech prosthetic is very, very fascinating and there’s actually been a lot of really amazing work that’s been happening in academia.
言语假肢非常非常令人着迷,实际上学术界已经发生了很多令人惊叹的工作。
Sergey Stavisky at UC Davis, Jaimie Henderson and late Krishna Shenoy at Stanford, are doing just some incredible amount of work in improving speech neuro-prosthetics.
加州大学戴维斯分校的谢尔盖·斯塔维斯基 (Sergey Stavisky)、斯坦福大学的杰米·亨德森 (Jaimie Henderson) 和已故的斯坦福大学的克里希纳·谢诺伊 (Krishna Shenoy) 在改进言语神经修复术方面做了一些令人难以置信的工作。
And those are actually looking more at parts of the motor cortex that are controlling these vocal articulators, and being able to, even by mouthing the word or imagine speech, you can pick up those signals.
这些实际上更多地关注控制这些发声器官的运动皮层部分,并且即使通过说出单词或想象语音,您也可以拾取这些信号。
3:32:31 The more sophisticated higher level processing areas like the Broca’s area or Wernicke’s area, those are still very, very big mystery in terms of the underlying mechanism of how all that stuff works.
更复杂的高级处理区域,如布罗卡区或韦尼克区,就所有这些东西如何工作的基本机制而言,这些仍然是非常非常大的谜团。
But I mean, I think Neuralink’s eventual goal is to understand those things and be able to provide a platform and tools to be able to understand that and study that.
但我的意思是,我认为 Neuralink 的最终目标是理解这些东西,并能够提供一个平台和工具来理解和研究这些东西。
This is where I get to the pothead questions.
这就是我要回答的傻瓜问题。
3:32:58 Do you think we can start getting insight into things like thought?
你认为我们可以开始洞察思想等事物吗?
So, speech, there’s a muscular component, like you said, there’s the act of producing sounds, but then what about the internal things like cognition, like low-level thoughts and high-level thoughts?
所以,言语,有一个肌肉成分,就像你说的,有发出声音的行为,但是像认知这样的内部事物,比如低层次的思想和高层次的思想呢?
Do you think we’ll start noticing signals that could be picked up, they could be understood, that could be maybe used in order to interact with the outside world?
你认为我们会开始注意到可以被接收、可以理解、可以用来与外界互动的信号吗?
In some ways, I guess, this starts to kind of get into the hard problem of consciousness.
我想,在某些方面,这开始陷入意识的难题。
3:33:35 And I mean, on one hand, all of these are at some point, set of electrical signals that from there maybe it in itself is giving you the cognition or the meaning, or somehow human mind is an incredibly amazing storytelling machine.
我的意思是,一方面,所有这些在某个时刻都是一组电信号,从那里它本身可能会给你认知或意义,或者以某种方式人类的大脑是一个令人难以置信的惊人的讲故事的机器。
So, we’re telling ourselves and fooling ourselves that there’s some interesting meaning here.
所以,我们告诉自己并欺骗自己,这里有一些有趣的含义。
3:34:13 But I mean, I certainly think that BCI …
但我的意思是,我当然认为 BCI ……
Really, BCI, at the end of the day is a set of tools that help you study the underlying mechanisms in a both local but also broader sense, and whether there’s some interesting patterns of electrical signal that means you’re thinking this versus …
事实上,BCI 归根结底是一套工具,可以帮助您从局部和更广泛的意义上研究潜在机制,以及是否存在一些有趣的电信号模式,这意味着您正在思考这一点与……
And you can either learn from many, many sets of data to correlate some of that and be able to do mind reading or not.
你可以从很多很多数据集中学习,将其中的一些数据关联起来,并能够读心术,也可以不读心术。
I’m not sure.
我不知道。
3:34:47 I certainly would not rule that out as a possibility, but I think BCI alone probably can’t do that.
我当然不会排除这种可能性,但我认为仅靠 BCI 可能无法做到这一点。
There’s probably additional set of tools and framework and also just hard problem of consciousness, at the end of the day, is rooted in this philosophical question of what is the meaning of it all?
可能还有一套额外的工具和框架,而且意识的难题,归根结底,植根于这个哲学问题:这一切的意义是什么?
What’s the nature of our existence?
我们存在的本质是什么?
Where’s the mind emerged from this complex network?
这个复杂的网络中的思想从哪里出现?
Yeah.
是的。
3:35:13 How does the subjective experience emerge from just a bunch of spikes, electrical spikes?
主观体验是如何从一堆尖峰、电尖峰中产生的?
Yeah.
是的。
3:35:21 Yeah.
是的。
I mean, we do really think about BCI and what we’re building as a tool for understanding the mind, the brain.
我的意思是,我们确实认真考虑了 BCI 以及我们正在构建的用于理解思想和大脑的工具。
The only question that matters.
唯一重要的问题。
3:35:34 There actually is some biological existence proof of what it would take to kind of start to form some of these experiences that may be unique.
事实上,有一些生物存在证据表明,需要什么才能开始形成这些可能是独特的体验。
If you actually look at every one of our brains, there are two hemispheres.
如果你仔细观察我们的每一个大脑,就会发现有两个半球。
There’s a left-sided brain, there’s a right-sided brain.
有左脑,有右脑。
And unless you have some other conditions, you normally don’t feel like left legs or right legs, you just feel like one legs, right?
除非你有其他情况,否则你通常感觉不到左腿或右腿,你只是感觉像一条腿,对吧?
So, what is happening there?
那么,那里发生了什么?
Right?
正确的?
3:36:10 If you actually look at the two hemispheres, there’s a structure that kind of connectorized the two, called the corpus callosum, that is supposed to have around 200 to 300 million connections or axons.
如果你真正观察两个半球,就会发现有一种结构将两个半球连接起来,称为胼胝体,它应该有大约 200 到 3 亿个连接或轴突。
So, whether that means that’s the number of interface and electrodes that we need to create some sort of mind meld or from that whatever new conscious experience that you can experience.
所以,这是否意味着我们需要创建某种心灵融合所需的接口和电极的数量,或者从中您可以体验到的任何新的意识体验。
But I do think that there’s kind of an interesting existence proof that we all have.
但我确实认为我们都有一个有趣的存在证据。
And that threshold is unknown at this time?
而这个门槛目前还不知道?
Oh, yeah.
哦,是的。
3:36:55 Everything in this domain is speculation.
这个领域的一切都是猜测。
Right?
正确的?
And then, you’d be continuously pleasantly surprised.
然后,你会不断地感到惊喜。
3:37:00 Do you see a world where there is millions of people, like tens of millions, hundreds of millions of people walking around with a Neuralink device or multiple Neuralink devices in their brain?
你是否看到过这样一个世界:有数百万人、数千万人、数亿人的大脑中带着一个或多个 Neuralink 设备四处走动?
I do.
我愿意。
3:37:20 First of all, there are, if you look at worldwide, people suffering from movement disorders and visual deficits, I mean, that’s in the tens if not hundreds of millions of people.
首先,如果你看看全世界,我的意思是,有数千万甚至数亿人患有运动障碍和视力缺陷。
So, that alone, I think there’s a lot of benefit and potential good that we can do with this type of technology.
因此,仅此一点,我认为我们可以利用此类技术带来很多好处和潜在的好处。
And once you start to get into psychiatric application, depression, anxiety, hunger or obesity, right?
一旦你开始进入精神病学应用,抑郁、焦虑、饥饿或肥胖,对吗?
Mood, control of appetite.
情绪、食欲的控制。
I mean, that starts to become very real to everyone.
我的意思是,这对每个人来说都开始变得非常现实。
Not to mention that most people on Earth have a smartphone, and once BCI starts competing with a smartphone as a preferred methodology of interacting with the digital world, that also becomes an interesting thing.
更不用说地球上大多数人都拥有智能手机,一旦 BCI 开始与智能手机竞争作为与数字世界交互的首选方法,这也成为一件有趣的事情。
Oh yeah, this is even before going to that, right?
哦,是的,这甚至是在那之前,对吧?
3:38:24 There’s almost, I mean, the entire world that could benefit from these types of things.
我的意思是,几乎整个世界都可以从这些类型的事情中受益。
And then, if we’re talking about next generation of how we interface with machines or even ourselves, in many ways, I think BCI can play a role in that.
然后,如果我们谈论下一代我们与机器甚至我们自己的交互方式,在很多方面,我认为 BCI 可以在其中发挥作用。
And some of the things that I also talk about is, I do think that there is a real possibility that you could see 8 billion people walking around with Neuralink.
我还谈到的一些事情是,我确实认为你确实有可能看到 80 亿人与 Neuralink 一起行走。
Well, thank you so much for pushing ahead.
嗯,非常感谢您的推动。
3:38:58 And I look forward to that exciting future.
我期待着那个令人兴奋的未来。
Thanks for having me.
谢谢你有我。
Thanks for listening to this conversation with DJ Seo.
感谢您收听 DJ Seo 的对话。
3:39:06 And now, dear friends, here’s Matthew MacDougall, the head neurosurgeon at Neuralink.
现在,亲爱的朋友们,这是 Neuralink 的首席神经外科医生 Matthew MacDougall。
3:39:17 When did you first become fascinated with the human brain?
您什么时候第一次对人脑着迷?
Since forever.
自永远以来。
3:39:21 As far back as I can remember, I’ve been interested in the human brain.
从我记事起,我就对人脑感兴趣。
I mean, I was a thoughtful kid and a bit of an outsider, and you sit there thinking about what the most important things in the world are in your little tiny adolescent brain.
我的意思是,我是一个有思想的孩子,有点局外人,你坐在那里思考世界上最重要的事情在你小小的青春期大脑中。
And the answer that I came to, that I converged on was that all of the things you can possibly conceive of as things that are important for human beings to care about are literally contained in the skull.
我得出的、我集中的答案是,所有你可能想到的对人类来说重要的、需要关心的东西实际上都包含在头骨中。
Both the perception of them and their relative values and the solutions to all our problems, and all of our problems, are all contained in the skull.
无论是对它们的感知还是它们的相对价值以及我们所有问题的解决方案,以及我们所有的问题,都包含在头骨中。
And if we knew more about how that worked, how the brain encodes information and generates desires and generates agony and suffering, we could do more about it.
如果我们更多地了解它是如何运作的,大脑如何编码信息并产生欲望并产生痛苦和痛苦,我们就可以做得更多。
3:40:27 You think about all the really great triumphs in human history.
你想想人类历史上所有真正伟大的胜利。
You think about all the really horrific tragedies.
你想想所有真正可怕的悲剧。
You think about the Holocaust, you think about any prison full of human stories, and all of those problems boil down to neurochemistry.
你想想大屠杀,你想想任何充满人类故事的监狱,所有这些问题都归结为神经化学。
So, if you get a little bit of control over that, you provide people the option to do better.
因此,如果你对此有一点控制权,你就可以为人们提供做得更好的选择。
In the way I read history, the way people have dealt with having better tools is that they most often, in the end, do better, with huge asterisks.
以我阅读历史的方式来看,人们对待拥有更好工具的方式是,他们最终通常会做得更好,并带有巨大的星号。
But I think it’s an interesting, a worthy, a noble pursuit to give people more options, more tools.
但我认为为人们提供更多选择、更多工具是一种有趣、有价值、崇高的追求。
Yeah, that’s a fascinating way to look at human history.
是的,这是看待人类历史的一种有趣的方式。
3:41:16 You just imagine all these neurobiological mechanisms, Stalin, Hitler, Genghis Khan, all of them just had a brain, just a bunch of neurons, few times of billions of neurons gaining a bunch of information over a period of time.
你想象一下所有这些神经生物学机制,斯大林、希特勒、成吉思汗,他们都只有一个大脑,只有一堆神经元,数十亿个神经元在一段时间内获得一堆信息。
They have a set of modules that does language and memory and all that.
他们有一组模块可以处理语言和记忆等等。
And from there, in the case of those people, they’re able to murder millions of people.
从那里开始,就这些人而言,他们能够谋杀数百万人。
And all that coming from …
而这一切都来自……
There’s not some glorified notion of a dictator of this enormous mind or something like this.
没有任何关于拥有如此巨大思想的独裁者的美化概念或类似的东西。
It’s just the brain.
这只是大脑。
Yeah.
是的。
3:41:59 Yeah.
是的。
I mean, a lot of that has to do with how well people like that can organize those around them.
我的意思是,这在很大程度上与这样的人能否很好地组织周围的人有关。
Other brains.
其他大脑。
Yeah.
是的。
3:42:09 And so, I always find it interesting to look to primatology, look to our closest non-human relatives for clues as to how humans are going to behave and what particular humans are able to achieve.
因此,我总是觉得研究灵长类动物学,研究我们最亲近的非人类亲戚,寻找关于人类将如何行为以及特定人类能够实现什么的线索。
And so, you look at chimpanzees and bonobos, and they’re similar but different in their social structures particularly.
所以,你看看黑猩猩和倭黑猩猩,它们很相似,但在社会结构上尤其不同。
And I went to Emory in Atlanta and studied under the great Frans de Waal, who was kind of the leading primatologist, who recently died.
我去了亚特兰大的埃默里大学,师从伟大的弗兰斯·德瓦尔,他是一位顶尖的灵长类动物学家,最近去世了。
And his work looking at chimps through the lens of how you would watch an episode of Friends and understand the motivations of the characters interacting with each other.
他的作品通过你如何观看《老友记》一集的镜头来观察黑猩猩,并了解角色之间互动的动机。
He would look at a chimp colony and basically apply that lens.
他会观察黑猩猩群体并基本上应用这个镜头。
I’m massively oversimplifying it.
我把它过于简单化了。
3:43:05 If you do that, instead of just saying, “Subject 473 threw his feces at subject 471.” You talk about them in terms of their human struggles, accord them the dignity of themselves as actors with understandable goals and drives, what they want out of life.
如果你这样做,而不是仅仅说“对象 473 将粪便扔向对象 471”。你从他们的人类斗争的角度来谈论他们,赋予他们作为演员的尊严,他们有可以理解的目标和动力,他们想从生活中得到什么。
And primarily, it’s the things we want out of life, food, sex, companionship, power.
主要是我们想要从生活中得到的东西:食物、性、陪伴、权力。
You can understand chimp and bonobo behavior in the same lights much more easily.
您可以更轻松地从相同的角度理解黑猩猩和倭黑猩猩的行为。
And I think doing so gives you the tools you need to reduce human behavior from the kind of false complexity that we layer onto it with language, and look at it in terms of, oh, well, these humans are looking for companionship, sex, food, power.
我认为这样做可以为你提供所需的工具,以减少人类行为的那种虚假复杂性,我们用语言将其分层,并以,哦,好吧,这些人类正在寻找陪伴,性,食物,权力来看待它。
And I think that that’s a pretty powerful tool to have in understanding human behavior.
我认为这是理解人类行为的一个非常强大的工具。
And I just went to the Amazon jungle for a few weeks and it’s a very visceral reminder that a lot of life on Earth is just trying to get laid.
我刚刚去了亚马逊丛林几周,这非常发自内心地提醒我,地球上的许多生命只是想上床。
3:44:10 They’re all screaming at each other.
他们都互相尖叫。
I saw a lot of monkeys and they’re just trying to impress each other, or maybe if there’s a battle for power, but a lot of the battle for power has to do with them getting laid.
我看到很多猴子,它们只是想给对方留下深刻印象,或者也许是为了权力之战,但很多权力之战都与它们上床有关。
Right.
正确的。
3:44:33 Breeding rights often go with alpha status.
育种权通常与阿尔法地位相关。
And so, if you can get a piece of that, then you’re going to do okay.
所以,如果你能从中分得一杯羹,那你就做得很好了。
And we’d like to think that we’re somehow fundamentally different, and especially when it comes to primates, we really aren’t.
我们想认为我们在某种程度上有本质上的不同,尤其是对于灵长类动物来说,我们确实没有。
3:44:40 We can use fancier poetic language, but maybe some of the underlying drives and motivators are similar.
我们可以使用更奇特的诗意语言,但也许一些潜在的驱动力和动机是相似的。
Yeah, I think that’s true.
是的,我认为这是真的。
And all of that is coming from this, the brain.
所有这一切都来自大脑。
Yeah.
是的。
So, when did you first start studying the brain as the biological mechanism?
那么,您什么时候开始研究大脑作为生物机制的呢?
Basically, the moment I got to college, I started looking around for labs that I could do neuroscience work in.
基本上,从我进入大学的那一刻起,我就开始寻找可以进行神经科学工作的实验室。
3:45:07 I originally approached that from the angle of looking at interactions between the brain and the immune system, which isn’t the most obvious place to start, but I had this idea at the time that the contents of your thoughts would have a direct impact, maybe a powerful one, on non-conscious systems in your body.
我最初是从大脑和免疫系统之间相互作用的角度来看待这个问题的,这并不是最明显的起点,但当时我有一个想法,你的思想内容会对你体内的无意识系统产生直接影响,也许是强大的影响。
The systems we think of as homeostatic automatic mechanisms, like fighting off a virus, like repairing a wound.
我们认为的系统是稳态自动机制,就像抵抗病毒,就像修复伤口一样。
And sure enough, there are big crossovers between the two.
果然,两者之间存在很大的交叉。
3:45:55 I mean, it gets to kind of a key point that I think goes under-recognized.
我的意思是,这已经到了一个我认为没有得到充分认识的关键点。
One of the things people don’t recognize or appreciate about the human brain enough, and that is that it basically controls or has a huge role in almost everything that your body does.
人们对人类大脑认识不足或欣赏不够的一件事是,它基本上控制着你身体所做的几乎所有事情,或者在其中发挥着巨大作用。
You try to name an example of something in your body that isn’t directly controlled or massively influenced by the brain, and it’s pretty hard.
你试图举一个你身体中不受大脑直接控制或严重影响的东西的例子,这非常困难。
I mean, you might say like bone healing or something.
我的意思是,你可能会说骨头愈合之类的。
But even those systems, the hypothalamus and pituitary end up playing a role in coordinating the endocrine system, that does have a direct influence on say, the calcium level in your blood, that goes to bone healing.
但即使是这些系统,下丘脑和垂体最终也会在协调内分泌系统中发挥作用,这确实会对血液中的钙水平产生直接影响,从而促进骨骼愈合。
So, non-obvious connections between those things implicate the brain as really a potent prime mover in all of health.
因此,这些事物之间不明显的联系表明大脑确实是所有健康的强大原动力。
One of the things I realized in the other direction too, how most of the systems in the body are integrated with the human brain, they affect the brain also, like the immune system.
我在另一个方向上也意识到了其中一件事,体内的大多数系统如何与人脑整合,它们也会影响大脑,就像免疫系统一样。
3:46:55 I think there’s just, people who study Alzheimer’s and those kinds of things, it’s just surprising how much you can understand of that from the immune system, from the other systems that don’t obviously seem to have anything to do with the nervous system.
我认为,研究阿尔茨海默氏症和此类疾病的人,令人惊讶的是,你可以从免疫系统、从其他似乎与神经系统没有任何关系的系统中了解这一点。
They all play together.
他们都一起玩。
Yeah, you could understand how that would be driven by evolution too.
是的,你也可以理解这是如何由进化驱动的。
3:47:28 Just in some simple examples, if you get sick, if you get a communicable disease, you get the flu, it’s pretty advantageous for your immune system to tell your brain, “Hey, now be antisocial for a few days.
举几个简单的例子,如果你生病了,如果你得了传染病,你得了流感,你的免疫系统会告诉你的大脑,“嘿,现在反社会几天。
Don’t go be the life of the party tonight.
今晚别成为聚会的焦点。
In fact, maybe just cuddle up somewhere warm, under a blanket, and just stay there for a day or two.” And sure enough, that tends to be the behavior that you see both in animals and in humans.
事实上,也许只是蜷缩在温暖的地方,盖上毯子,然后在那里呆一两天。”果然,这往往是你在动物和人类身上看到的行为。
If you get sick, elevated levels of interleukins in your blood and TNF-alpha in your blood, ask the brain to cut back on social activity and even moving around, you have lower locomotor activity in animals that are infected with viruses.
如果你生病了,血液中白细胞介素和肿瘤坏死因子-α的水平升高,就会要求大脑减少社交活动,甚至四处走动,感染病毒的动物的运动活动就会降低。
So, from there, the early days in neuroscience to surgery, when did that step happen?
那么,从神经科学的早期到外科手术,这一步发生在什么时候?
3:48:25 Which is a leap.
这是一个飞跃。
Yeah.
是的。
3:48:34 It was sort of an evolution of thought.
这是一种思想的演变。
I wanted to study the brain.
我想研究大脑。
I started studying the brain in undergrad in this neuroimmunology lab.
我本科时就开始在这个神经免疫学实验室研究大脑。
I, from there, realized at some point that I didn’t want to just generate knowledge.
从那时起,我在某个时候意识到我不想仅仅产生知识。
I wanted to affect real changes in the actual world, in actual people’s lives.
我想影响现实世界、人们生活中的真正变化。
And so, after having not really thought about going into medical school, I was on a track to go into a PhD program.
因此,在没有真正考虑过进入医学院之后,我正准备攻读博士学位。
I said, “Well, I’d like that option.
我说:“好吧,我想要这个选择。
I’d like to actually potentially help tangible people in front of me.”
我实际上希望能够帮助我面前的有形的人。”
3:49:18 And doing a little digging, found that there exists these MD-PhD programs where you can choose not to choose between them and do both.
经过一番挖掘,发现存在这些医学博士-博士项目,您可以选择不在它们之间进行选择,而是两者都做。
And so, I went to USC for medical school and had a joint PhD program with Caltech, where I actually chose that program particularly because of a researcher at Caltech named Richard Andersen, who’s one of the godfathers of primate neuroscience, and has a macaque lab where Utah arrays and other electrodes were being inserted into the brains of monkeys to try to understand how intentions were being encoded in the brain.
因此,我去了南加州大学医学院,并与加州理工学院联合攻读博士学位课程,实际上我之所以选择该课程,是因为加州理工学院的一位名叫理查德·安德森的研究员,他是灵长类神经科学的教父之一,并拥有一个猕猴实验室,犹他阵列和其他电极被插入猴子的大脑中,试图了解意图是如何在大脑中编码的。
3:50:03 So, I ended up there with the idea that maybe I would be a neurologist and study the brain on the side.
所以,我最终产生了这样的想法:也许我会成为一名神经科医生,同时研究大脑。
And then discovered that neurology …
然后发现神经病学......
Again, I’m going to make enemies by saying this, but neurology predominantly and distressingly to me, is the practice of diagnosing a thing and then saying, “Good luck with that.
再说一遍,我会因为这样说而树敌,但神经病学对我来说主要且令人痛苦的是诊断一件事然后说:“祝你好运。
There’s not much we can do.” And neurosurgery, very differently, it’s a powerful lever on taking people that are headed in a bad direction and changing their course in the sense of brain tumors that are potentially treatable or curable with surgery.
我们无能为力。”而神经外科则截然不同,它是一个强大的杠杆,可以帮助人们走向错误的方向,并改变他们的病程,即可以通过手术治疗或治愈的脑肿瘤。
Even aneurysms in the brain, blood vessels that are going to rupture, you can save lives, really, is at the end of the day what mattered to me.
即使是脑部动脉瘤、即将破裂的血管,你也可以挽救生命,这对我来说真的是最重要的。
3:50:59 And so, I was at USC, as I mentioned, that happens to be one of the great neurosurgery programs.
所以,正如我提到的,我在南加州大学,这恰好是最伟大的神经外科项目之一。
And so, I met these truly epic neurosurgeons, Alex Khalessi, and Mike Apuzzo, and Steve Giannotta, and Marty Weiss, these epic people that were just human beings in front of me.
因此,我遇到了这些真正伟大的神经外科医生,亚历克斯·卡莱西、迈克·阿普佐、史蒂夫·吉安诺塔和马蒂·韦斯,这些伟大的人在我面前只是人类。
And so, it kind of changed my thinking from neurosurgeons are distant gods that live on another planet and occasionally come and visit us, to these are humans that have problems and are people, and there’s nothing fundamentally preventing me from being one of them.
因此,这改变了我的想法,从神经外科医生是生活在另一个星球上、偶尔会来拜访我们的遥远的神,到这些人是有问题的人,也是人,没有什么从根本上阻止我成为他们中的一员。
And so, at the last minute in medical school, I changed gears from going into a different specialty and switched into neurosurgery, which cost me a year.
因此,在医学院的最后一刻,我改变了方向,从不同的专业转向神经外科,这花了我一年的时间。
I had to do another year of research because I was so far along in the process that to switch into neurosurgery, the deadlines had already passed.
我必须再进行一年的研究,因为我已经在转入神经外科的过程中进行了很长时间,截止日期已经过去了。
So, it was a decision that cost time, but absolutely worth it.
因此,这是一个花费时间的决定,但绝对值得。
What was the hardest part of the training on the neurosurgeon track?
神经外科医生培训中最难的部分是什么?
Yeah, two things, I think, that residency in neurosurgery is sort of a competition of pain, of how much pain can you eat and smile?
是的,我认为有两件事,神经外科住院医师实习是一种疼痛的竞争,你能承受多少痛苦并微笑?
3:52:14 And so, there’s work hour restrictions that are not really …
因此,工作时间限制实际上并不是……
They’re viewed, I think, internally among the residents as weakness.
我认为,他们在居民内部被视为弱点。
And so, most neurosurgery residents try to work as hard as they can, and that, I think necessarily means working long hours and sometimes over the work hour limits.
因此,大多数神经外科住院医师都尽力工作,我认为这必然意味着长时间工作,有时甚至超过工作时间限制。
3:52:49 We care about being compliant with whatever regulations are in front of us, but I think more important than that, people want to give their all in becoming a better neurosurgeon because the stakes are so high.
我们关心的是遵守我们面前的任何法规,但我认为比这更重要的是,人们希望全力以赴成为一名更好的神经外科医生,因为风险如此之高。
And so, it’s a real fight to get residents to say, go home at the end of their shift and not stay and do more surgery.
因此,让居民说,在轮班结束后回家,而不是留下来做更多手术,这是一场真正的斗争。
Are you seriously saying one of the hardest things is literally forcing them to get sleep and rest and all this kind of stuff?
你是认真地说最困难的事情之一就是强迫他们睡觉和休息以及诸如此类的事情吗?
Historically that was the case.
历史上确实如此。
That’s hilarious.
太搞笑了。
3:53:21 And that’s awesome.
那太棒了。
I think the next generation is more compliant and more self-care-
我认为下一代会更顺从、更自理——
Weaker is what you mean.
你的意思是比较弱。
3:53:29 All right.
好的。
I’m just kidding.
我只是在开玩笑。
I’m just kidding.
我只是在开玩笑。
I didn’t say it.
我没说。
Now I’m making enemies.
现在我正在树敌。
No.
不。
Okay, I get it.
好的,我明白了。
3:53:35 Wow, that’s fascinating.
哇,太有趣了。
So, what was the second thing?
那么,第二件事是什么?
The personalities.
个性。
3:53:39 And maybe the two are connected.
也许两者是有联系的。
So, was it pretty competitive?
那么,它很有竞争力吗?
It’s competitive, and it’s also, as we touched on earlier, primates like power.
它具有竞争性,而且正如我们之前提到的,灵长类动物也喜欢权力。
3:53:45 And I think neurosurgery has long had this aura of mystique and excellence and whatever about it.
我认为神经外科长期以来一直具有神秘和卓越的光环等等。
And so, it’s an invitation, I think, for people that are cloaked in that authority.
因此,我认为,这是对那些披着权威外衣的人的邀请。
A board certified neurosurgeon is basically a walking fallacious appeal to authority.
获得委员会认证的神经外科医生基本上是对权威的错误诉求。
Right?
正确的?
You have license to walk into any room and act like you’re an expert on whatever.
你有权走进任何房间并表现得好像你是某方面的专家。
And fighting that tendency is not something that most neurosurgeons do well.
大多数神经外科医生并不擅长对抗这种倾向。
Humility isn’t the forte.
谦虚并不是强项。
Yeah.
是的。
3:54:28 I have friends who know you and whenever they speak about you that you have the surprising quality for a neurosurgeon of humility, which I think indicates that it’s not as common as perhaps in other professions, because there is a kind of gigantic sort of heroic aspect to neurosurgery, and I think it gets to people’s head a little bit.
我有认识你的朋友,每当他们谈论你时,他们都会说你具有神经外科医生所具有的令人惊讶的谦逊品质,我认为这表明这种品质在其他职业中并不常见,因为神经外科有一种巨大的英雄气概,我认为这有点让人难以理解。
Yeah.
是的。
3:54:54 Well, I think that allows me to play well at an Elon company because Elon, one of his strengths, I think, is to just instantly see through fallacy from authority.
嗯,我认为这让我能够在埃隆公司发挥出色,因为我认为埃隆的优势之一就是能够立即看穿权威的谬误。
So, nobody walks into a room that he’s in and says, “Well, goddammit, you have to trust me.
所以,没有人走进他所在的房间说:“好吧,该死,你必须相信我。
I’m the guy that built the last 10 rockets,” or something.
我是最后 10 枚火箭的制造者”之类的。
And he says, “Well, you did it wrong and we can do it better.” Or, “I’m the guy that kept Ford alive for the last 50 years.
他说:“好吧,你做错了,我们可以做得更好。”或者,“我是让福特在过去 50 年里保持活力的人。
You listen to me on how to build cars.” And he says, “No.”
你听我讲如何造汽车。”他说:“不。”
3:55:34 And so, you don’t walk into a room that he’s in and say, “Well, I’m a neurosurgeon.
因此,你不会走进他所在的房间并说:“嗯,我是一名神经外科医生。
Let me tell you how to do it.” He’s going to say, “Well, I’m a human being that has a brain.
让我告诉你该怎么做。”他会说:“好吧,我是一个有大脑的人。
I can think from first principles myself.
我自己可以从第一原则出发思考。
Thank you very much.
非常感谢。
And here’s how I think it ought to be done.
我认为应该这样做。
Let’s go try it and see who’s right.” And that’s proven, I think over and over in his case, to be a very powerful approach.
我们去试试吧,看看谁是对的。”我在他的案例中反复思考,这已被证明是一种非常有效的方法。
If we just take that tangent, there’s a fascinating interdisciplinary team at Neuralink that you get to interact with, including Elon.
如果我们正题的话,Neuralink 有一个令人着迷的跨学科团队,你可以与他们互动,其中包括 Elon。
3:55:57 What do you think is the secret to a successful team?
您认为一个成功团队的秘诀是什么?
What have you learned from just getting to observe these folks, world experts in different disciplines work together?
通过观察这些不同学科的世界专家的合作,您学到了什么?
There’s a sweet spot where people disagree and forcefully speak their mind and passionately defend their position, and yet, are still able to accept information from others and change their ideas when they’re wrong.
有一个最佳点,即人们不同意并强力表达自己的想法并热情地捍卫自己的立场,但仍然能够接受他人的信息并在错误时改变自己的想法。
3:56:21 And so, I like the analogy of how you polish rocks.
所以,我喜欢抛光岩石的类比。
You put hard things in a hard container and spin it.
您将坚硬的东西放入坚硬的容器中并旋转它。
People bash against each other, and out comes a more refined product.
人们互相攻击,最终产生了更精致的产品。
And so, to make a good team at Neuralink, we’ve tried to find people that are not afraid to defend their ideas passionately and occasionally strongly disagree with people that they’re working with, and have the best idea come out on top.
因此,为了在 Neuralink 打造一支优秀的团队,我们试图找到那些不怕热情地捍卫自己的想法、偶尔会强烈反对与他们一起工作的人的人,并且让最好的想法脱颖而出。
3:57:20 It’s not an easy balance.
这不是一个容易的平衡。
Again, to refer back to the primate brain.
再次回到灵长类动物的大脑。
It’s not something that is inherently built into the primate brain to say, “I passionately put all my chips on this position, and now I’m just going to walk away from it and admit you are right.” Part of our brains tell us that that is a power loss, that is a loss of face, a loss of standing in the community, and now you’re a zeta chump because your idea got trounced.
灵长类动物的大脑中并没有固有的说法:“我热情地把所有的筹码都放在了这个位置上,现在我要离开它并承认你是对的。”我们大脑的一部分告诉我们,这是一种权力损失,一种面子损失,一种在社区中的地位损失,而现在你是一个 zeta 傻瓜,因为你的想法被挫败了。
And you just have to recognize that that little voice in the back of your head is maladaptive and it’s not helping the team win.
你只需要认识到,你脑后的那个小声音是不适应的,它不会帮助球队获胜。
Yeah, you have to have the confidence to be able to walk away from an idea that you hold on to.
是的,你必须有信心能够摆脱你坚持的想法。
3:58:04 Yeah.
是的。
Yeah.
是的。
And if you do that often enough, you’re actually going to become the best in the world at your thing.
如果你经常这样做,你实际上就会在你的领域成为世界上最好的。
3:58:08 I mean, that rapid iteration.
我的意思是,快速迭代。
Yeah, you’ll at least be a member of a winning team.
是的,你至少会成为获胜团队的一员。
Ride the wave.
乘风破浪。
3:58:22 What did you learn …
你学到了什么……
You mentioned there’s a lot of amazing neurosurgeons at USC.
你提到南加州大学有很多出色的神经外科医生。
What lessons about surgery and life have you learned from those folks?
您从这些人身上学到了哪些关于手术和生活的教训?
Yeah.
是的。
3:58:35 I think working your ass off, working hard while functioning as a member of a team, getting a job done that is incredibly difficult, working incredibly long hours, being up all night, taking care of someone that you think probably won’t survive no matter what you do.
我认为拼命工作,作为团队成员努力工作,完成一项非常困难的工作,工作时间非常长,彻夜不眠,照顾一个你认为无论你做什么都可能无法生存的人。
Working hard to make people that you passionately dislike look good the next morning.
努力让你非常不喜欢的人第二天早上看起来很好。
3:59:06 These folks were relentless in their pursuit of excellent neurosurgical technique, decade over decade, and I think were well-recognized for that excellence.
这些人十多年来不懈地追求卓越的神经外科技术,我认为他们的卓越表现得到了广泛认可。
So, especially Marty Weiss, Steve Giannotta, Mike Apuzzo, they made huge contributions not only to surgical technique, but they built training programs that trained dozens or hundreds of amazing neurosurgeons.
因此,特别是马蒂·韦斯 (Marty Weiss)、史蒂夫·吉安诺塔 (Steve Giannotta)、迈克·阿普佐 (Mike Apuzzo),他们不仅在外科技术方面做出了巨大贡献,而且还建立了培训项目,培训了数十名或数百名出色的神经外科医生。
I was just lucky to be in their wake.
我很幸运能跟在他们后面。
What’s that like …
那是什么样的……
3:59:42 You mentioned doing a surgery where the person is likely not to survive.
您提到进行手术时,患者很可能无法生存。
Does that wear on you?
这对你有用吗?
Yeah.
是的。
3:59:54 It’s especially challenging when you …
当你……时,这尤其具有挑战性。
With all respect to our elders, it doesn’t hit so much when you’re taking care of an 80-year-old, and something was going to get them pretty soon anyway.
恕我直言,当你照顾一个 80 岁的老人时,这对我们的长辈来说并没有那么大的打击,而且无论如何,他们很快就会得到一些东西。
And so, you lose a patient like that, and it was part of the natural course of what is expected of them in the coming years, regardless.
因此,你失去了这样的病人,无论如何,这是未来几年对他们的期望的自然过程的一部分。
4:00:36 Taking care of a father of two or three, four young kids, someone in their 30s that didn’t have it coming, and they show up in your ER having their first seizure of their life, and lo and behold, they’ve got a huge malignant inoperable or incurable brain tumor.
照顾一个有两三个、四个小孩的父亲,一个30多岁的人,没有患上这种疾病,他们出现在你的急诊室,第一次癫痫发作,你瞧,他们患有巨大的恶性脑瘤,无法手术或无法治愈。
You can only do that, I think, a handful of times before it really starts eating away at your armor.
我认为,你只能这样做几次,然后它才真正开始侵蚀你的盔甲。
Or, a young mother that shows up that has a giant hemorrhage in her brain that she’s not going to survive from.
或者,一位年轻的母亲出现,她的大脑出现严重出血,她将无法生存。
And they bring her four-year-old daughter in to say goodbye one last time before they turn the ventilator off.
他们带着她四岁的女儿进来最后一次道别,然后才关掉呼吸机。
The great Henry Marsh is an English neurosurgeon who said it best, I think.
我认为,伟大的亨利·马什是一位英国神经外科医生,他说得最好。
He says, “Every neurosurgeon carries with them a private graveyard.” And I definitely feel that, especially with young parents, that kills me.
他说:“每个神经外科医生都带着一个私人墓地。”我确实感觉到,尤其是对于年轻的父母来说,这让我很伤心。
They had a lot more to give.
他们还有很多东西可以奉献。
The loss of those people specifically has a knock-on effect that’s going to make the world worse for people for a long time.
这些人的流失会产生连锁反应,在很长一段时间内让世界变得更糟。
And it’s just hard to feel powerless in the face of that.
面对这种情况,很难感到无能为力。
And that’s where I think you have to be borderline evil to fight against a company like Neuralink or to constantly be taking pot shots at us, because what we’re doing is to try to fix that stuff.
这就是我认为你必须处于邪恶边缘才能与 Neuralink 这样的公司作斗争,或者不断地对我们进行攻击,因为我们正在做的就是试图解决这些问题。
We’re trying to give people options to reduce suffering.
我们正在努力为人们提供减少痛苦的选择。
We’re trying to take the pain out of life that broken brains brings in.
我们正在努力消除大脑破碎给生活带来的痛苦。
And yeah, this is just our little way that we’re fighting back against entropy, I guess.
是的,我想这只是我们对抗熵的小方法。
Yeah.
是的。
4:02:52 The amount of suffering that’s endured when some of the things that we take for granted that our brain is able to do is taken away, is immense.
当我们认为大脑能够做的一些事情被剥夺时,我们所承受的痛苦是巨大的。
And to be able to restore some of that functionality is a real gift.
能够恢复部分功能是一份真正的礼物。
Yeah.
是的。
4:03:06 We’re just starting.
我们才刚刚开始。
We’re going to do so much more.
我们还会做更多的事情。
Well, can you take me through the full procedure for implanting, say, the N1 chip in Neuralink?
那么,您能带我完成在 Neuralink 中植入 N1 芯片的完整过程吗?
Sure.
当然。
4:03:18 Yeah.
是的。
It’s a really simple, straightforward procedure.
这是一个非常简单、直接的过程。
The human part of the surgery that I do is dead simple.
我所做的手术中的人体部分非常简单。
It’s one of the most basic neurosurgery procedures imaginable.
这是可以想象到的最基本的神经外科手术之一。
And I think there’s evidence that some version of it has been done for thousands of years.
我认为有证据表明它的某些版本已经存在了数千年。
That there are examples, I think, from ancient Egypt of healed or partially healed trepanations, and from Peru or ancient times in South America where these proto-surgeons would drill holes in people’s skulls, presumably to let out the evil spirits, but maybe to drain blood clots.
我认为,古埃及有治愈或部分治愈的环钻术的例子,还有秘鲁或古代南美洲的原始外科医生会在人们的头骨上钻孔,大概是为了释放邪灵,但也可能是为了排出血块。
And there’s evidence of bone healing around the edge, meaning the people at least survived some months after a procedure.
有证据表明边缘周围的骨头愈合,这意味着人们在手术后至少存活了几个月。
4:04:11 And so, what we’re doing is that.
所以,我们正在做的就是这个。
We are making a cut in the skin on the top of the head over the area of the brain that is the most potent representation of hand intentions.
我们正在头顶大脑区域的皮肤上做一个切口,这是手部意图最有效的表现。
And so, if you are an expert concert pianist, this part of your brain is lighting up the entire time you’re playing.
所以,如果你是一位专业的音乐会钢琴家,你大脑的这一部分在你演奏的整个过程中都会被点亮。
We call it the hand knob.
我们称之为手柄。
The hand knob.
手旋钮。
4:04:36 So, it’s all the finger movements, all of that is just firing away.
所以,这就是所有的手指动作,所有这些都只是发射。
Yep.
是的。
4:04:43 There’s a little squiggle in the cortex right there.
那里的皮质里有一点波浪线。
One of the folds in the brain is kind of doubly folded right on that spot.
大脑中的一个褶皱就在那个地方双重折叠。
And so, you can look at it on an MRI and say, “That’s the hand knob.” And then you do a functional test and a special kind of MRI called a functional MRI, fMRI.
所以,你可以在 MRI 上观察它并说:“那是手柄。”然后进行功能测试和一种特殊的 MRI,称为功能 MRI,fMRI。
And this part of the brain lights up when-
当——时,大脑的这一部分就会亮起来——
4:05:00 MRI, fMRI, and this part of the brain lights up when people, even quadriplegic people whose brains aren’t connected to their finger movements anymore, they imagine finger movements and this part of the brain still lights up.
MRI、功能磁共振成像和当人们,甚至大脑不再与手指运动连接的四肢瘫痪的人想象手指运动时,大脑的这一部分仍然会亮起来。
So we can ID that part of the brain in anyone who’s preparing to enter our trial and say, okay, that part of the brain we confirm is your hand intention area.
因此,我们可以识别任何准备参加我们试验的人的大脑部分,然后说,好吧,我们确认的大脑部分是你的手部意图区域。
And so I’ll make a little cut in the skin, we’ll flap the skin open, just like kind of opening the hood of a car, only a lot smaller, make a perfectly round one inch diameter hole in the skull, remove that bit of skull, open the lining of the brain, the covering of the brain, it’s like a little bag of water that the brain floats in, and then show that part of the brain to our robot.
所以我会在皮肤上做一个小切口,我们会打开皮肤,就像打开汽车引擎盖一样,只是小得多,在头骨上做一个直径一英寸的完美圆形孔,去除那块头骨,打开大脑的内壁,大脑的覆盖物,就像大脑漂浮在其中的一小袋水,然后向我们的机器人展示大脑的这一部分。
And then this is where the robot shines.
这就是机器人的闪光点。
4:06:01 It can come in and take these tiny, much smaller than human hair, electrodes and precisely insert them into the cortex, into the surface of the brain to a very precise depth, in a very precise spot that avoids all the blood vessels that are coating the surface of the brain.
它可以进入并获取这些比人类头发小得多的微小电极,并将它们精确地插入皮质、大脑表面的非常精确的深度,在一个非常精确的位置,避开覆盖大脑表面的所有血管。
And after the robot’s done with its part, then the human comes back in and puts the implant into that hole in the skull and covers it up, screwing it down to the skull and sewing the skin back together.
机器人完成它的部分后,人类就会回来,将植入物放入头骨上的那个洞中,并将其盖住,将其拧到头骨上,然后将皮肤缝合在一起。
So the whole thing is a few hours long.
所以整个事情持续了几个小时。
It’s extremely low risk compared to the average neurosurgery involving the brain that might, say, open up a deeper part of the brain or manipulate blood vessels in the brain.
与涉及大脑的普通神经外科手术相比,这种手术的风险极低,例如,打开大脑更深的部分或操纵大脑中的血管。
This opening on the surface of the brain with only cortical micro- insertions carries significantly less risk than a lot of the tumor or aneurysm surgeries that are routinely done.
与许多常规进行的肿瘤或动脉瘤手术相比,仅进行皮质微插入的大脑表面开口的风险要低得多。
So cortical micro-insertions that are via robot and computer vision are designed to avoid the blood vessels.
因此,通过机器人和计算机视觉进行的皮质微插入旨在避开血管。
Exactly.
确切地。
So I know you’re a bit biased here, but let’s compare human and machine.
所以我知道你在这里有点偏见,但让我们比较一下人类和机器。
4:07:19 So what are human surgeons able to do well and what are robot surgeons able to do well at this stage of our human civilization and development?
那么,在人类文明发展的现阶段,人类外科医生能做什么,机器人外科医生能做什么呢?
Yeah.
是的。
4:07:36 Yeah, that’s a good question.
是的,这是一个好问题。
Humans are general purpose machines.
人类是通用机器。
We’re able to adapt to unusual situations.
我们能够适应不寻常的情况。
We’re able to change the plan on the fly.
我们能够即时更改计划。
I remember well a surgery that I was doing many years ago down in San Diego where the plan was to open a small hole behind the ear and go reposition a blood vessel that had come to lay on the facial nerve, the trigeminal nerve, the nerve that goes to the face.
我清楚地记得很多年前我在圣地亚哥做过一次手术,计划是在耳后打开一个小孔,然后重新定位位于面神经、三叉神经、通向面部的神经上的血管。
When that blood vessel lays on the nerve, it can cause just intolerable, horrific shooting pain that people describe like being zapped with a cattle prod.
当血管覆盖在神经上时,会引起难以忍受的、可怕的刺痛,人们形容这种疼痛就像被牛棒击中一样。
And so the beautiful, elegant surgery is to go move this blood vessel off the nerve.
因此,美丽而优雅的手术就是将这条血管从神经上移开。
The surgery team, we went in there and started moving this blood vessel and then found that there was a giant aneurysm on that blood vessel that was not easily visible on the pre-op scans.
手术团队,我们进去并开始移动这条血管,然后发现该血管上有一个巨大的动脉瘤,在术前扫描中不容易看到。
And so the plan had to dynamically change and that the human surgeons had no problem with that, were trained for all those things.
因此,计划必须动态改变,而人类外科医生对此没有任何问题,他们接受了所有这些事情的培训。
4:08:50 Robots wouldn’t do so well in that situation, at least in their current incarnation, fully robotic surgery, like the electrode insertion portion of the neural link surgery, it goes according to a set plan.
机器人在这种情况下不会做得那么好,至少在它们目前的化身中,完全机器人手术,就像神经连接手术的电极插入部分一样,它按照既定计划进行。
And so the humans can interrupt the flow and change the plan, but the robot can’t really change the plan midway through.
因此,人类可以中断流程并更改计划,但机器人无法真正中途更改计划。
It operates according to how it was programmed and how it was asked to run.
它根据编程方式和要求运行方式进行操作。
It does its job very precisely, but not with a wide degree of latitude in how to react to changing conditions.
它非常精确地完成自己的工作,但在如何应对不断变化的条件方面没有很大的自由度。
So there could be just a very large number of ways that you could be surprised as a surgeon?
那么作为一名外科医生,可能有很多方式会让你感到惊讶?
4:09:29 When you enter a situation, there could be subtle things that you have to dynamically adjust to.
当你进入一种情况时,可能会有一些微妙的事情需要你动态调整。
Correct.
正确的。
And robots are not good at that.
而机器人不擅长这一点。
Currently.
现在。
Currently.
现在。
I think we are at the dawn of a new era with AI of the parameters for robot responsiveness to be dramatically broadened, right?
我认为我们正处于一个新时代的黎明,人工智能的机器人响应能力参数将显着扩大,对吗?
4:09:44 I mean, you can’t look at a self-driving car and say that it’s operating under very narrow parameters.
我的意思是,你不能看着自动驾驶汽车并说它在非常狭窄的参数下运行。
If a chicken runs across the road, it wasn’t necessarily programmed to deal with that specifically, but a Waymo or a self-driving Tesla would have no problem reacting to that appropriately.
如果一只鸡跑过马路,它不一定会被编程来专门处理这种情况,但 Waymo 或自动驾驶特斯拉可以毫无问题地做出适当的反应。
And so surgical robots aren’t there yet, but give it time.
所以手术机器人还没有出现,但还需要时间。
And then there could be a lot of semi-autonomous possibilities of maybe a robotic surgeon could say this situation is perfectly familiar, or this situation is not familiar, and in the not familiar case, a human could take over, but basically be very conservative in saying, okay, this for sure has no issues, no surprises, and let the humans deal with the surprises with the edge cases and all that.
然后可能有很多半自主的可能性,也许机器人外科医生可以说这种情况完全熟悉,或者这种情况不熟悉,在不熟悉的情况下,人类可以接管,但基本上非常保守地说,好吧,这肯定没有问题,没有惊喜,让人类处理边缘情况等的惊喜。
4:10:23 That’s one possibility.
这是一种可能性。
So you think eventually you’ll be out of the job?
所以你认为你最终会失业吗?
Well, you being neurosurgeon, your job being a neurosurgeon.
好吧,你是神经外科医生,你的工作就是神经外科医生。
Humans, there will not be many neurosurgeons left on this earth.
人类,这个地球上不会剩下多少神经外科医生了。
I’m not worried about my job in the course of my professional life.
在我的职业生涯中,我并不担心我的工作。
4:11:06 I think I would tell my kids not necessarily to go in this line of work depending on how things look in 20 years.
我想我会告诉我的孩子不一定要从事这一行,这取决于20年后的情况。
It’s so fascinating because if I have a line of work, I would say it’s programming.
这太令人着迷了,因为如果我有一份工作,我会说它是编程。
4:11:24 And if you ask me, for the last, I don’t know, 20 years, what I would recommend for people, I would tell them, yeah, you’ll always have a job if you’re a programmer because there’s more and more computers and all this kind of stuff and it pays well.
如果你问我,在过去的 20 年里,我不知道我会向人们推荐什么,我会告诉他们,是的,如果你是一名程序员,你总会有一份工作,因为有越来越多的计算机和所有这些东西,而且薪水很高。
But then you realize these large language models come along and they’re really damn good at generating code.
但后来你意识到这些大型语言模型的出现,它们非常擅长生成代码。
So overnight you could be surprised like, wow, what is the contribution of the human really?
所以一夜之间你可能会感到惊讶,哇,人类到底做出了什么贡献?
But then you start to think, okay, it does seem that humans have ability, like you said, to deal with novel situations.
但后来你开始思考,好吧,人类似乎确实有能力,就像你说的,处理新情况。
In the case of programming, it’s the ability to come up with novel ideas to solve problems.
就编程而言,它是提出新想法来解决问题的能力。
It seems like machines aren’t quite yet able to do that.
机器似乎还不能做到这一点。
And when the stakes are very high, when it’s life critical as it is in surgery, especially in neurosurgery, then the stakes are very high for a robot to actually replace a human.
当风险非常高时,当外科手术(尤其是神经外科手术)对生命至关重要时,机器人真正取代人类的风险就非常高。
But it’s fascinating that in this case of Neuralink, there’s a human robot collaboration.
但令人着迷的是,在 Neuralink 的案例中,存在人类与机器人的协作。
Yeah, yeah.
是啊是啊。
4:12:34 I do the parts it can’t do and it does the parts I can’t do, and we are friends.
我做它不能做的部分,它也做我不能做的部分,我们是朋友。
I saw that there’s a lot of practice going on.
我看到正在进行很多练习。
4:12:45 I mean everything in Neuralink is tested extremely rigorously, but one of the things I saw that there’s a proxy on which the surgeries are performed.
我的意思是 Neuralink 中的所有内容都经过了极其严格的测试,但我看到的其中一件事是有一个执行手术的代理。
So this is both for the robot and for the human, for everybody involved in the entire pipeline.
因此,这既适用于机器人,也适用于人类,适用于整个管道中涉及的每个人。
What’s that like, practicing the surgery?
练习手术是什么感觉?
It’s pretty intense.
非常激烈。
4:13:07 So there’s no analog to this in human surgery.
所以在人体手术中没有类似的东西。
Human surgery is sort of this artisanal craft that’s handed down directly from master to pupil over the generations.
人体外科手术是一种手工技艺,由师傅直接传给学生,代代相传。
I mean, literally the way you learn to be a surgeon on humans is by doing surgery on humans.
我的意思是,从字面上看,你学习成为人类外科医生的方法就是通过对人类进行手术。
I mean, first you watch your professors do a bunch of surgery, and then finally they put the trivial parts of the surgery into your hands, and then the more complex parts, and as your understanding of the point and the purposes of the surgery increases, you get more responsibility in the perfect condition.
我的意思是,首先你看着你的教授做一堆手术,然后最后他们把手术的琐碎部分交给你,然后是更复杂的部分,随着你对手术要点和目的的理解的增加,你在完美的情况下承担了更多的责任。
Doesn’t always go well.
并不总是顺利。
In Neuralink’s case, the approach is a bit different.
在 Neuralink 的例子中,方法有点不同。
We, of course, practiced as far as we could on animals.
当然,我们尽可能在动物身上进行练习。
We did hundreds of animal surgeries.
我们做了数百例动物手术。
And when it came time to do the first human, we had just an amazing team of engineers build incredibly lifelike models.
当需要制作第一个人时,我们有一支出色的工程师团队构建了极其逼真的模型。
One of the engineers, Fran Romano in particular, built a pulsating brain in a custom 3-D printed skull that matches exactly the patient’s anatomy, including their face and scalp characteristics.
其中一位工程师,特别是 Fran Romano,在定制的 3D 打印头骨中构建了一个脉动的大脑,该头骨与患者的解剖结构完全匹配,包括他们的面部和头皮特征。
4:14:35 And so when I was able to practice that, it’s as close as it really reasonably should get to being the real thing in all the details, including having a mannequin body attached to this custom head.
因此,当我能够练习时,它在所有细节上都尽可能接近真实,包括将人体模型身体连接到这个定制头部。
And so when we were doing the practice surgeries, we’d wheel that body into the CT scanner and take a mock CT scan and wheel it back in and conduct all the normal safety checks, verbally, “Stop.
因此,当我们进行练习手术时,我们会将尸体推入 CT 扫描仪并进行模拟 CT 扫描,然后将其推回原位并进行所有正常的安全检查,口头上说:“停止。
This patient we’re confirming his identification is mannequin number…” Blah, blah, blah.
我们正在确认这名患者的身份是人体模型编号……”等等,等等,等等。
And then opening the brain in exactly the right spot using standard operative neuro-navigation equipment, standard surgical drills in the same OR that we do all of our practice surgeries in at Neuralink and having the skull open and have the brain pulse, which adds a degree of difficulty for the robot to perfectly precisely plan and insert those electrodes to the right depth and location.
然后使用标准手术神经导航设备在正确的位置打开大脑,使用与我们在 Neuralink 进行所有练习手术相同的标准手术钻头打开头骨并获得大脑脉冲,这增加了机器人完美精确地计划并将这些电极插入正确深度和位置的难度。
And so we kind of broke new ground on how extensively we practiced for this surgery.
因此,我们在这次手术的练习范围方面开辟了新天地。
So there was a historic moment, a big milestone for Neuralink, in part for humanity, with the first human getting a Neuralink implant in January of this year.
因此,出现了一个历史性的时刻,对 Neuralink 来说是一个重要的里程碑,部分是对人类来说,今年 1 月第一个人类植入了 Neuralink。
4:15:52 Take me through the surgery on Noland.
带我完成诺兰德的手术。
What did it feel like to be part of this?
参与其中感觉如何?
Yeah.
是的。
4:16:13 Well, we are lucky to have just incredible partners at the Barrow Neurologic Institute.
嗯,我们很幸运能够在巴罗神经病学研究所拥有令人难以置信的合作伙伴。
They are, I think, the premier neurosurgical hospital in the world.
我认为他们是世界上最好的神经外科医院。
They made everything as easy as possible for the trial to get going and helped us immensely with their expertise on how to arrange the details.
他们让试验的一切变得尽可能简单,并利用他们在如何安排细节方面的专业知识为我们提供了巨大帮助。
It was a much more high pressure surgery in some ways.
从某些方面来说,这是一次高压得多的手术。
I mean, even though the outcome wasn’t particularly in question in terms of our participant’s safety, the number of observers, the number of people, there’s conference rooms full of people watching live streams in the hospital rooting for this to go perfectly, and that just adds pressure that is not typical for even the most intense production neurosurgery, say, removing a tumor or placing deep brain stimulation electrodes, and it had never been done on a human before.
我的意思是,尽管就我们的参与者的安全、观察者的数量、人数而言,结果并不是特别有问题,但医院的会议室里挤满了观看直播的人,他们都在为这一过程的完美进行而欢呼,而这只会增加压力,这对于最密集的神经外科手术来说也是不常见的,比如切除肿瘤或放置深部脑刺激电极,而且以前从未在人类身上做过这样的事情。
There were unknown unknowns.
有未知的未知数。
4:17:27 And so definitely a moderate pucker factor there for the whole team not knowing if we were going to encounter, say, a degree of brain movement that was unanticipated or a degree of brain sag that took the brain far away from the skull and made it difficult to insert or some other unknown unknown problem.
因此,对于整个团队来说,这绝对是一个中等程度的皱褶因素,不知道我们是否会遇到,比如说,一定程度的意外的大脑运动,或者一定程度的大脑下垂,使大脑远离头骨,使其难以插入或其他一些未知的未知问题。
Fortunately everything went well and that surgery is one of the smoothest outcomes we could have imagined.
幸运的是,一切都很顺利,手术是我们能想象到的最顺利的结果之一。
Were you nervous?
你紧张吗?
Extremely.
极其。
I mean, you’re a bit of a quarterback in the Super Bowl kind of situation.
我的意思是,在超级碗的情况下,你有点像四分卫。
Extremely nervous.
极度紧张。
4:18:07 Extremely.
极其。
I was very pleased when it went well and when it was over.
当一切进展顺利和结束时,我都感到非常高兴。
Looking forward to number two.
期待第二名。
Even with all that practice, all of that, you’ve never been in a situation that’s so high stakes in terms of people watching.
即使进行了所有这些练习,所有这些,就人们观看而言,你从未遇到过如此高风险的情况。
4:18:17 And we should also probably mention, given how the media works, a lot of people may be in a dark kind of way hoping it doesn’t go well.
我们还应该提到,考虑到媒体的运作方式,很多人可能会以一种黑暗的方式希望事情进展不顺利。
I think wealth is easy to hate or envy or whatever, and I think there’s a whole industry around driving clicks and bad news is great for clicks, and so any way to take an event and turn it into bad news is going to be really good for clicks.
我认为财富很容易让人讨厌或嫉妒或其他什么,而且我认为整个行业都围绕着点击量而展开,而坏消息对点击量来说非常有利,因此任何将事件变成坏消息的方式都会对点击量非常有利。
It just sucks because I think it puts pressure on people.
这很糟糕,因为我认为这会给人们带来压力。
4:19:00 It discourages people from trying to solve really hard problems because to solve hard problems, you have to go into the unknown.
它阻止人们尝试解决真正困难的问题,因为要解决困难问题,你必须进入未知领域。
You have to do things that haven’t been done before and you have to take risks, calculated risks, you have to do all kinds of safety precautions, but risks nevertheless.
你必须做以前没有做过的事情,你必须承担风险,计算出的风险,你必须采取各种安全预防措施,但风险仍然存在。
I just wish there would be more celebration of that, of the risk taking versus people just waiting on the sidelines waiting for failure and then pointing out the failure.
我只是希望能有更多的庆祝活动,庆祝冒险,而不是人们只是在一旁等待失败,然后指出失败。
Yeah, it sucks.
是的,这很糟糕。
But in this case, it’s really great that everything went just flawlessly, but it’s unnecessary pressure, I would say.
但在这种情况下,一切都很完美,这真的很棒,但我想说,这是不必要的压力。
Now that there’s a human with literal skin in the game, there’s a participant whose well-being rides on this doing well.
现在,游戏中有了一个真正的“皮肤”,一个参与者的福祉取决于他的良好表现。
4:19:41 You have to be a pretty person to be rooting for that to go wrong.
你必须是一个漂亮的人才能支持这种错误。
And so hopefully people look in the mirror and realize that at some point.
因此,希望人们照镜子时能意识到这一点。
So did you get to actually front row seat, watch the robot work?
那么,您是否真正坐在前排座位上观看机器人工作?
4:20:01 You get to see the whole thing?
你能看到整个事情吗?
Yeah, because an MD needs to be in charge of all of the medical decision-making throughout the process, I unscrubbed from the surgery after exposing the brain and presenting it to the robot and placed the targets on the robot software interface that tells the robot where it’s going to insert each thread.
是的,因为医学博士需要负责整个过程中的所有医疗决策,所以在暴露大脑并将其呈现给机器人之后,我从手术中解脱出来,并将目标放置在机器人软件界面上,告诉机器人它将在哪里插入每个线程。
4:20:08 That was done with my hand on the mouse, for whatever that’s worth.
无论值多少钱,我的手都放在鼠标上完成了。
So you were the one placing the targets?
所以你就是那个设定目标的人?
Yeah.
是的。
Oh, cool.
哦,酷。
4:20:42 So the robot with a computer vision provides a bunch of candidates and you kind of finalize the decision.
因此,具有计算机视觉的机器人提供了一堆候选者,然后你就可以最终确定决定。
Right.
正确的。
4:20:52 The software engineers are amazing on this team, and so they actually provided an interface where you can essentially use a lasso tool and select a prime area of brain real estate, and it will automatically avoid the blood vessels in that region and automatically place a bunch of targets.
这个团队的软件工程师非常出色,所以他们实际上提供了一个界面,您基本上可以使用套索工具并选择大脑房地产的主要区域,它会自动避开该区域的血管并自动放置一堆目标。
That allows the human robot operator to select really good areas of brain and make dense applications of targets in those regions, the regions we think are going to have the most high fidelity representations of finger movements and arm movement intentions.
这使得人类机器人操作员能够选择真正好的大脑区域,并在这些区域中密集应用目标,我们认为这些区域将具有手指运动和手臂运动意图的最高保真度表示。
I’ve seen images of this and for me with OCD, for some reason, are really pleasant.
我看过这样的图像,对于患有强迫症的我来说,出于某种原因,真的很令人愉快。
4:21:37 I think there’s a Subreddit called Oddly Satisfying.
我认为有一个名为“奇怪的满足”的 Reddit 子版块。
Yeah, love that Subreddit.
是的,喜欢那个 Reddit 子版块。
It’s oddly satisfying to see the different target sites avoiding the blood vessels and also maximizing the usefulness of those locations for the signal.
奇怪的是,看到不同的目标部位避开血管,并最大限度地利用这些位置的信号,真是令人感到满意。
4:21:49 It just feels good.
感觉很好。
It’s like, ah.
就好像,啊。
As a person who has a visceral reaction to the brain bleeding, I can tell you it’s extremely satisfying watching the electrodes themselves go into the brain and not cause bleeding.
作为一个对脑出血有本能反应的人,我可以告诉你,看到电极本身进入大脑而不引起出血是非常令人满意的。
Yeah.
是的。
4:22:12 Yeah.
是的。
So you said the feeling was of relief when everything went perfectly?
所以你说当一切都很顺利时感觉如释重负?
Yeah.
是的。
How deep in the brain can you currently go and eventually go, let’s say on the Neuralink side.
你目前能进入并最终进入大脑多深的地方,比如说 Neuralink 一侧。
4:22:20 It seems the deeper you go in the brain, the more challenging it becomes.
似乎你进入大脑越深,它就变得越具有挑战性。
Yeah.
是的。
4:22:34 So talking broadly about neurosurgery, we can get anywhere.
因此,广泛地谈论神经外科,我们可以取得任何进展。
It’s routine for me to put deep brain stimulating electrodes near the very bottom of the brain, entering from the top and passing about a two millimeter wire all the way into the bottom of the brain.
我的惯例是在大脑最底部附近放置深部大脑刺激电极,从顶部进入并穿过大约两毫米的电线一直进入大脑底部。
And that’s not revolutionary, a lot of people do that, and we can do that with very high precision.
这并不是革命性的,很多人都这样做,而且我们可以以非常高的精度做到这一点。
I use a robot from Globus to do that surgery several times a month.
我每个月都会使用 Globus 的机器人进行几次这样的手术。
It’s pretty routine.
这很例行公事。
What are your eyes in that situation?
在这种情况下你的眼睛是什么?
4:23:12 What are you seeing?
你看到什么了?
What kind of technology can you use to visualize where you are to light your way?
您可以使用哪种技术来可视化您所在的位置并照亮您的道路?
Yeah, so it’s a cool process on the software side.
是的,所以这在软件方面是一个很酷的过程。
4:23:20 You take a preoperative MRI that’s extremely high resolution, data of the entire brain, you put the patient to sleep, put their head in a frame that holds the skull very rigidly, and then you take a CT scan of their head while they’re asleep with that frame on and then merge the MRI and the CT in software.
你需要在术前进行极高分辨率的 MRI 扫描,获取整个大脑的数据,然后让患者入睡,将他们的头部放入一个牢固地固定头骨的框架中,然后在他们睡着时在框架上对他们的头部进行 CT 扫描,然后在软件中合并 MRI 和 CT。
You have a plan based on the MRI where you can see these nuclei deep in the brain.
您有一个基于 MRI 的计划,您可以在其中看到大脑深处的这些核。
You can’t see them on CT, but if you trust the merging of the two images, then you indirectly know on the CT where that is, and therefore indirectly know where in reference to the titanium frame screwed to their head those targets are.
你在 CT 上看不到它们,但如果你相信两个图像的合并,那么你就可以在 CT 上间接知道它们在哪里,因此相对于拧到头部的钛框架,你可以间接知道这些目标在哪里。
And so this is sixties technology to manually compute trajectories given the entry point and target and dial in some goofy looking titanium manual actuators with little tick marks on them.
因此,这是六十年代的技术,可以在给定入口点和目标的情况下手动计算轨迹,并拨入一些看起来愚蠢的钛手动执行器,其上带有小刻度线。
4:24:32 The modern version of that is to use a robot.
现代版本是使用机器人。
Just like a little Kuka arm you might see building cars at the Tesla factory, this small robot arm can show you the trajectory that you intended from the pre-op MRI and establish a very rigid holder through which you can drill a small hole in the skull and pass a small rigid wire deep into that area of the brain that’s hollow, and put your electrode through that hollow wire and then remove all of that except the electrode.
就像你在特斯拉工厂制造汽车时可能会看到的库卡小手臂一样,这个小型机器人手臂可以向你显示术前核磁共振成像中你想要的轨迹,并建立一个非常坚固的支架,通过它你可以在头骨上钻一个小孔,将一根小刚性电线深入到大脑的中空区域,然后将电极穿过那根中空电线,然后移除除电极之外的所有东西。
So you end up with the electrode very, very precisely placed far from the skull surface.
因此,最终电极非常非常精确地放置在远离头骨表面的位置。
Now, that’s standard technology that’s already been out in the world for a while.
现在,这是已经在世界上出现一段时间的标准技术。
Neuralink right now is focused entirely on cortical targets, surface targets because there’s no trivial way to get, say, hundreds of wires deep inside the brain without doing a lot of damage.
Neuralink 目前完全专注于皮质目标和表面目标,因为没有简单的方法可以在不造成很大损害的情况下将数百根电线深入大脑内部。
So your question, what do you see?
所以你的问题是,你看到了什么?
Well, I see an MRI on a screen.
嗯,我在屏幕上看到了核磁共振成像。
I can’t see everything that DBS electrode is passing through on its way to that deep target.
我看不到 DBS 电极在到达深层目标的过程中所经过的一切。
4:25:48 And so it’s accepted with this approach that there’s going to be about one in a hundred patients who have a bleed somewhere in the brain as a result of passing that wire blindly into the deep part of the brain.
因此,人们普遍认为,这种方法会导致大约百分之一的患者因盲目地将电线插入大脑深处而导致大脑某处出血。
That’s not an acceptable safety profile for Neuralink.
对于 Neuralink 来说,这不是可接受的安全配置。
We start from the position that we want this to be dramatically maybe two or three orders of magnitude safer than that, safe enough, really, that you or I, without a profound medical problem, might on our lunch break someday say, “Yeah, sure, I’ll get that.
我们的立场是,我们希望它比那个安全得多,可能要安全两到三个数量级,足够安全,真的,你或我,如果没有严重的医疗问题,有一天可能会在午休时说:“是的,当然,我会明白的。
I’d been meaning to upgrade to the latest version.” And so the safety constraints given that are high, and so we haven’t settled on a final solution for arbitrarily approaching deep targets in the brain.
我一直想升级到最新版本。”因此,安全限制很高,因此我们还没有确定任意接近大脑深层目标的最终解决方案。
It’s interesting because you have to avoid blood vessels somehow, and you have to…
这很有趣,因为你必须以某种方式避开血管,而且你必须……
4:26:46 Maybe there’s creative ways of doing the same thing, like mapping out high resolution geometry of blood vessels, and then you can go in blind, but how do you map out that in a way that’s super stable?
也许有一些创造性的方法可以做同样的事情,比如绘制血管的高分辨率几何形状,然后你可以盲目地进行,但是你如何以超级稳定的方式绘制它呢?
There’s a lot of interesting challenges there, right?
那里有很多有趣的挑战,对吗?
Yeah.
是的。
But there’s a lot to do on the surface.
但表面上还有很多事情要做。
Exactly.
确切地。
4:27:07 So we’ve got vision on the surface.
所以我们的愿景只是表面上的。
We actually have made a huge amount of progress sewing electrodes into the spinal cord as a potential workaround for a spinal cord injury that would allow a brain mounted implant to translate motor intentions to a spine mounted implant that can affect muscle contractions in previously paralyzed arms and legs.
实际上,我们已经在将电极缝入脊髓方面取得了巨大进展,作为脊髓损伤的潜在解决方法,这将使大脑安装的植入物将运动意图转化为脊柱安装的植入物,从而影响先前瘫痪的手臂和腿部的肌肉收缩。
That’s mind blowing.
这真是令人兴奋。
4:27:36 That’s just incredible.
这太不可思议了。
So the effort there is to try to bridge the brain to the spinal cord to the peripheral in your nervous…
因此,我们需要努力将大脑、脊髓和神经末梢连接起来……
So how hard is that to do?
那么这有多难做到呢?
We have that working in very crude forms in animals.
我们已经在动物身上以非常原始的形式发挥作用。
That’s amazing.
太棒了。
Yeah, we’ve done…
是的,我们已经做到了……
So similar to with Noland where he’s able to digitally move the cursor.
与诺兰非常相似,他能够以数字方式移动光标。
4:27:54 Here you’re doing the same kind of communication, but with the effectors that you have.
在这里,你正在进行同样类型的沟通,但使用的是你拥有的效应器。
Yeah.
是的。
That’s fascinating.
这很有趣。
So we have anesthetized animals doing grasp and moving their legs in a sort of walking pattern.
因此,我们让麻醉的动物以一种行走的方式抓握和移动它们的腿。
4:28:08 Again, early days, but the future is bright for this kind of thing, and people with paralysis should look forward to that bright future.
再说一遍,虽然还处于早期阶段,但这种事情的未来是光明的,瘫痪的人应该期待那个光明的未来。
They’re going to have options.
他们会有选择。
And there’s a lot of sort of intermediate or extra options where you take an optimist robot like the arm, and to be able to control the arm, the fingers and hands of the arm as a prosthetic.
还有很多中间或额外的选项,你可以使用像手臂这样的乐观机器人,并且能够控制手臂、手指和手臂作为假肢。
Exoskeletons are getting better too.
外骨骼也变得越来越好。
Exoskeletons.
外骨骼。
4:28:49 So that goes hand in hand.
所以这是齐头并进的。
Although I didn’t quite understand until thinking about it deeply and doing more research about Neuralink how much you can do on the digital side.
尽管我不太明白,直到深入思考并对 Neuralink 进行更多研究后,我才明白在数字方面可以做多少事情。
So this digital telepathy.
所以这种数字心灵感应。
I didn’t quite understand that you can really map the intention, as you described in the hand knob area, that you can map the intention.
我不太明白你真的可以映射意图,正如你在手柄区域所描述的那样,你可以映射意图。
Just imagine it.
想象一下吧。
Think about it.
想一想。
That intention can be mapped to actual action in the digital world, and now more and more, so much can be done in the digital world that it can reconnect you to the outside world.
这种意图可以映射到数字世界中的实际行动,现在数字世界中可以做的事情越来越多,以至于它可以将您与外部世界重新连接起来。
It can allow you to have freedom, have independence if you’re a quadriplegic.
如果您四肢瘫痪,它可以让您拥有自由和独立。
That’s really powerful.
这真的很强大。
You can go really far with that.
你可以走得很远。
Yeah, our first participant is…
是的,我们的第一位参与者是……
4:29:40 He’s incredible.
他太不可思议了。
He’s breaking world records left and right.
他不断打破世界纪录。
And he’s having fun with it.
他乐在其中。
4:29:46 It’s great.
这很棒。
Just going back to the surgery.
刚回去做手术。
Your whole journey, you mentioned to me offline you have surgery on Monday, so like you’re doing surgery all the time.
在你的整个旅程中,你在线下向我提到你周一要做手术,所以就像你一直在做手术一样。
Yeah.
是的。
Maybe the ridiculous question, what does it take to get good at surgery?
也许这是个可笑的问题,怎样才能擅长手术?
Practice, repetitions.
练习、重复。
4:30:04 Same with anything else.
与其他任何事情都一样。
There’s a million ways of people saying the same thing and selling books saying it, but you call it 10,000 hours, you call it spend some chunk of your life, some percentage of your life focusing on this, obsessing about getting better at it.
人们有一百万种方式说同样的话,卖书也这么说,但你称之为一万个小时,你称之为花费你生命中的一部分,你生命中的一部分专注于这件事,痴迷于变得更好。
Repetitions, humility, recognizing that you aren’t perfect at any stage along the way, recognizing you’ve got improvements to make in your technique, being open to feedback and coaching from people with a different perspective on how to do it, and then just the constant will to do better.
重复、谦逊、认识到自己在整个过程中的任何阶段都不完美、认识到自己的技术还有待改进、对如何做到这一点持开放态度的人的反馈和指导,然后就是不断做得更好的意愿。
That, fortunately, if you’re not a sociopath, I think your patients bring that with them to the office visits every day.
幸运的是,如果你不是反社会者,我认为你的病人每天都会带着它去办公室就诊。
They force you to want to do better all the time.
他们迫使你一直想要做得更好。
Yeah, just step up.
是的,只要站起来。
4:31:01 I mean, it’s a real human being, a real human being that you can help.
我的意思是,这是一个真实的人,一个你可以帮助的真实的人。
Yeah.
是的。
So every surgery, even if it’s the same exact surgery, is there a lot of variability between that surgery in a different person?
那么每次手术,即使是完全相同的手术,在不同的人身上进行的手术之间是否存在很大的差异?
Yeah.
是的。
4:31:15 A fair bit.
相当一点。
A good example for us is the angle of the skull relative to the normal plane of the body axis of the skull over hand knob is pretty wide variation.
对我们来说一个很好的例子是头骨相对于头骨身体轴法线平面的角度在手旋钮上变化很大。
Some people have really flat skulls and some people have really steeply angled skulls over that area, and that has consequences for how their head can be fixed in sort of the frame that we use and how the robot has to approach the skull.
有些人的头骨非常平坦,而有些人的头骨在该区域的角度非常陡峭,这会影响他们的头部如何固定在我们使用的框架中以及机器人如何接近头骨。
Yeah, people’s bodies are built as differently as the people you see walking down the street, as much variability and body shape and size as you see there.
是的,人们的身体结构就像你在街上看到的人一样不同,身体形状和尺寸的可变性也和你在那里看到的一样多。
We see in brain anatomy and skull anatomy, there are some people who we’ve had to exclude from our trial for having skulls that are too thick or too thin or scalp that’s too thick or too thin.
我们在大脑解剖学和头骨解剖学中看到,有些人因头骨太厚或太薄或头皮太厚或太薄而被排除在我们的试验之外。
I think we have the middle 97% or so of people, but you can’t account for all human anatomy variability.
我认为我们有 97% 左右的人,但你无法解释所有的人体解剖学变异。
How much mushiness and mess is there?
有多少糊状和混乱?
4:32:29 Because taking biology classes, the diagrams are always really clean and crisp.
因为上生物课,图表总是非常干净清晰。
Neuroscience, the pictures of neurons are always really nice and [inaudible 04:32:44], but whenever I look at pictures of real brains, they’re all…
神经科学,神经元的图片总是非常漂亮[听不清 04:32:44],但每当我看真实大脑的图片时,它们都是……
I don’t know what is going on.
我不知道发生了什么事。
So how much our biological systems in reality, how hard is it to figure out what’s going on?
那么我们的生物系统在现实中有多少,弄清楚正在发生的事情有多难?
Not too bad.
还不错。
4:32:59 Once you really get used to this, that’s where experience and skill and education really come into play is if you stare at a thousand brains, it becomes easier to kind of mentally peel back the, say, for instance, blood vessels that are obscuring the sulci and gyri, know kind of the wrinkle pattern of the surface of the brain.
一旦你真正习惯了这一点,这就是经验、技能和教育真正发挥作用的地方,如果你盯着一千个大脑,就会更容易在精神上剥离,比如说,遮盖脑沟和脑回的血管,了解大脑表面的皱纹模式。
Occasionally when you’re first starting to do this and you open the skull, it doesn’t match what you thought you were going to see based on the MRI.
有时,当您第一次开始这样做并打开头骨时,它与您根据 MRI 所看到的内容并不相符。
And with more experience, you learn to kind of peel back that layer of blood vessels and see the underlying pattern of wrinkles in the brain and use that as a landmark for where you are.
随着经验的积累,你会学会剥开那层血管,看到大脑中皱纹的潜在模式,并将其作为你所处位置的地标。
The wrinkles are a landmark?
皱纹是标志吗?
Yeah.
是的。
4:33:53 So I was describing hand knob earlier.
所以我之前描述过手动旋钮。
That’s a pattern of the wrinkles in the brain.
这是大脑皱纹的一种模式。
It’s sort of this Greek letter, omega shaped area of the brain.
它有点像希腊字母,大脑的欧米茄形状的区域。
So you could recognize the hand knob area.
这样您就可以识别手柄区域。
4:34:04 If I show you a thousand brains and give you one minute with each, you’d be like, “Yep, that’s that.”
如果我向你展示一千个大脑,并给你每个大脑一分钟的时间,你会说,“是的,就是这样。”
Sure.
当然。
And so there is some uniqueness to that area of the brain in terms of the geometry, the topology of the thing.
因此,大脑的那个区域在几何形状和拓扑结构方面有一些独特性。
Yeah.
是的。
Where is it about in the…
它大约在哪里?
So you have this strip of brain running down the top called the primary motor area, and I’m sure you’ve seen this picture of the homunculus laid over the surface of the brain, the weird little guy with huge lips and giant hands.
所以你有一条从顶部延伸的大脑带,称为初级运动区,我相信你已经看过这张小人的照片,它躺在大脑的表面上,这个奇怪的小家伙有巨大的嘴唇和巨大的手。
4:34:24 That guy sort of lays with his legs up at the top of the brain and face arm areas farther down, and then some kind of mouth, lip, tongue areas farther down.
那家伙躺着时,双腿向上,位于大脑顶部,手臂区域向下,然后是嘴、嘴唇、舌头区域向下。
And so the hand is right in there, and then the areas that control speech, at least on the left side of the brain in most people are just below that.
所以手就在那里,然后控制言语的区域,至少在大多数人的大脑左侧,就在这个区域的下面。
And so any muscle that you voluntarily move in your body, the vast majority of that references that strip or those intentions come from that strip of brain, and the wrinkle for hand knob is right in the middle of that.
因此,你体内自愿移动的任何肌肉,绝大多数涉及剥离或这些意图的参考都来自大脑的那条,而手把手的皱纹就在中间。
And vision is back here?
视力又回来了?
Yep.
是的。
Also close to the surface.
也接近表面。
Vision’s a little deeper.
愿景更深一点。
4:35:27 And so this gets to your question about how deep can you get.
所以这就引出了你的问题:你能走多深。
To do vision, we can’t just do the surface of the brain.
为了研究视觉,我们不能只研究大脑的表面。
We have to be able to go in, not as deep as we’d have to go for DBS, but maybe a centimeter deeper than we’re used to for hand insertions.
我们必须能够插入,不像 DBS 那样深,但可能比我们习惯的手插入深一厘米。
And so that’s work in progress.
这就是正在进行的工作。
That’s a new set of challenges to overcome.
这是一系列需要克服的新挑战。
By the way, you mentioned the Utah Array and I just saw a picture of that and that thing looks terrifying.
顺便说一句,你提到了犹他阵列,我刚刚看到了一张照片,那东西看起来很可怕。
Yeah.
是的。
4:36:02 The nails.
指甲。
It’s because it’s rigid and then if you look at the threads, they’re flexible.
这是因为它是刚性的,如果你看一下螺纹,它们是柔性的。
4:36:04 What can you say that’s interesting to you about that kind of approach of the flexible threads to deliver the electrodes next to the neurons?
您认为这种柔性线将电极传送到神经元旁边的方法有哪些让您感兴趣的地方?
Yeah.
是的。
4:36:18 I mean, the goal there comes from experience.
我的意思是,那里的目标来自于经验。
I mean, we stand on the shoulders of people that made Utah Arrays and used Utah Arrays for decades before we ever even came along.
我的意思是,我们站在那些制造犹他阵列并在我们出现之前数十年使用犹他阵列的人的肩膀上。
Neuralink arose, partly this approach to technology arose out of a need recognized after Utah Arrays would fail routinely because the rigid electrodes, those spikes that are literally hammered using an air hammer into the brain, those spikes generate a bad immune response that encapsulates the electrode spikes in scar tissue essentially.
Neuralink 的出现,部分是由于犹他阵列经常失败后认识到的一种需求,因为刚性电极,那些尖峰实际上是用气锤敲入大脑,这些尖峰产生了不良的免疫反应,基本上将电极尖峰封装在疤痕组织中。
And so one of the projects that was being worked on in the Anderson Lab at Caltech when I got there was to see if you could use chemotherapy to prevent the formation of scars.
因此,当我到达加州理工学院安德森实验室时,正在进行的项目之一就是看看是否可以使用化疗来防止疤痕的形成。
Things are pretty bad when you’re jamming a bed of nails into the brain, and then treating that with chemotherapy to try to prevent scar tissue, it’s like, maybe we’ve gotten off track here, guys.
当你把钉床钉进大脑,然后用化疗来防止疤痕组织形成时,情况会很糟糕,就像,也许我们已经偏离了轨道,伙计们。
Maybe there’s a fundamental redesign necessary.
也许有必要进行根本性的重新设计。
4:37:32 And so Neuralink’s approach of using highly flexible, tiny electrodes avoids a lot of the bleeding, avoids a lot of the immune response that ends up happening when rigid electrodes are pounded into the brain.
因此,Neuralink 使用高度灵活的微型电极的方法避免了大量出血,避免了将刚性电极敲入大脑时最终发生的大量免疫反应。
And so what we see is our electrode longevity and functionality and the health of the brain tissue immediately surrounding the electrode is excellent.
因此,我们看到的是我们的电极的寿命和功能以及电极周围的脑组织的健康状况非常好。
I mean, it goes on for years now in our animal models.
我的意思是,这种情况在我们的动物模型中已经持续了很多年。
What do most people not understand about the biology of the brain?
大多数人不了解大脑生物学的什么?
4:38:03 We will mention the vasculature.
我们会提到脉管系统。
That’s really interesting.
这真的很有趣。
I think the most interesting maybe underappreciated fact is that it really does control almost everything.
我认为最有趣的也许被低估的事实是它确实控制着几乎一切。
4:38:10 I don’t know, for an out of the blue example, imagine you want a lever on fertility.
我不知道,举个突然的例子,想象一下你想要一个提高生育率的杠杆。
You want to be able to turn fertility on and off.
您希望能够打开和关闭生育能力。
There are legitimate targets in the brain itself to modulate fertility, say blood pressure.
大脑本身有调节生育能力的合法目标,比如血压。
You want to modulate blood pressure, there are legitimate targets in the brain for doing that.
如果你想调节血压,大脑中有合理的目标可以做到这一点。
Things that aren’t immediately obvious as brain problems are potentially solvable in the brain.
那些不那么明显的大脑问题可能可以在大脑中得到解决。
And so I think it’s an under-explored area for primary treatments of all the things that bother people.
因此,我认为这是一个尚未充分探索的领域,可以对所有困扰人们的问题进行初步治疗。
That’s a really fascinating way to look at it.
这是一种非常有趣的看待它的方式。
4:39:04 There’s a lot of conditions we might think have nothing to do with the brain, but they might just be symptoms of something that actually started in the brain.
我们可能认为很多情况与大脑无关,但它们可能只是大脑中实际开始的症状。
The actual source of the problem, the primary source is something in the brain.
问题的真正根源,主要根源是大脑中的某些东西。
Yeah.
是的。
4:39:19 Not always.
并非总是如此。
I mean, kidney disease is real, but there are levers you can pull in the brain that affect all of these systems.
我的意思是,肾脏疾病是真实存在的,但你可以在大脑中施加影响所有这些系统的杠杆。
There’s knobs.
有旋钮。
Yeah.
是的。
On-off switches and knobs in the brain from which this all originates.
大脑中的开关和旋钮是这一切的起源。
4:39:32 Would you have a Neuralink chip implanted in your brain?
你会在你的大脑中植入 Neuralink 芯片吗?
Yeah.
是的。
4:39:42 I think use case right now is use a mouse, right?
我认为现在的用例是使用鼠标,对吧?
I can already do that, and so there’s no value proposition.
我已经可以做到这一点,所以没有价值主张。
On safety grounds alone, sure.
当然,仅出于安全考虑。
I’ll do it tomorrow.
我明天就做。
You know, when you say the use case of the mouse, is it…
你知道,当你说鼠标的用例时,是不是……
4:40:00 The use case of the mouse is after researching all this and part of it’s just watching Nolan have so much fun.
鼠标的用例是在研究了所有这些之后,部分原因是看到诺兰玩得很开心。
If you can get that bits per second look really high with the mouse, being able to interact, because if you think about the way on the smartphone, the way you swipe, that was transformational.
如果你能用鼠标让每秒的位数看起来非常高,就能进行交互,因为如果你想想智能手机上的方式,你滑动的方式,那就是变革。
How we interact with the thing, it’s subtle, you don’t realize it, but to be able to touch a phone and to scroll with your finger, that changed everything.
我们如何与事物互动,这是微妙的,你没有意识到这一点,但能够触摸手机并用手指滚动,这改变了一切。
People were sure you need a keyboard to type.
人们确信你需要键盘才能打字。
There’s a lot of HCI aspects to that that changed how we interact with computers, so there could be a certain rate of speed with the mouse that would change everything.
人机交互的很多方面改变了我们与计算机交互的方式,因此鼠标的一定速度可能会改变一切。
You might be able to just click around a screen extremely fast.
您也许可以非常快速地在屏幕上单击。
I can’t see myself getting a Neuralink for much more rapid interaction with the digital devices.
我不认为自己会使用 Neuralink 来与数字设备进行更快速的交互。
Yeah, I think recording speech intentions from the brain might change things as well, the value proposition for the average person.
是的,我认为记录大脑的言语意图也可能会改变普通人的价值主张。
4:41:03 A keyboard is a pretty clunky human interface, requires a lot of training.
键盘是一种相当笨重的人机界面,需要大量的培训。
It’s highly variable in the maximum performance that the average person can achieve.
普通人所能达到的最大绩效差异很大。
I think taking that out of the equation and just having a natural word to computer interface might change things for a lot of people.
我认为,将其排除在外,只需在计算机界面上使用自然的单词就可能会改变很多人的事情。
It’d be hilarious if that is the reason people do it.
如果这就是人们这样做的原因,那就太搞笑了。
4:41:40 Even if you have speech to text, that’s extremely accurate.
即使你有语音转文字,这也是非常准确的。
It currently isn’t, but it’d say you’ve gotten super accurate.
目前还不是,但它会说你已经变得非常准确。
It’d be hilarious if people went for Neuralink.
如果人们选择 Neuralink,那就太搞笑了。
Just so you avoid the embarrassing aspect of speaking, looking like a douchebag speaking to your phone in public, which is a real, that’s a real constraint.
这样你就可以避免说话时的尴尬,看起来像一个在公共场合对着手机说话的混蛋,这是一个真实的,这是一个真正的限制。
I mean with a bone conducting case, that can be an invisible headphone, say, and the ability to think words into software and have it respond to you.
我的意思是,对于骨传导外壳来说,它可以是一个隐形耳机,并且能够将单词输入软件并让它对你做出反应。
4:42:03 That starts to sound sort of like embedded super intelligence.
这听起来有点像嵌入式超级智能。
If you can silently ask for the Wikipedia article on any subject and have it read to you without any observable change happening in the outside world.
如果您可以默默地索取有关任何主题的维基百科文章并让其读给您听,而外部世界不会发生任何可观察到的变化。
For one thing, standardized testing is obsolete.
一方面,标准化测试已经过时。
If it’s done well in the UX side, it could change, I don’t know if it transforms society, but it really can create a kind of shift in the way we interact with digital devices in the way that a smartphone did.
如果它在用户体验方面做得很好,它可能会改变,我不知道它是否会改变社会,但它确实可以像智能手机那样改变我们与数字设备交互的方式。
4:42:43 Just having to look into the safety of everything involved, I would totally try it.
只要考虑到所涉及的一切的安全性,我就会完全尝试。
So it doesn’t have to go to some incredible thing where you have, it connects your vision or to some other, it connects all over your brain.
所以它不必去你拥有的一些令人难以置信的东西,它连接你的视觉或其他东西,它连接你的整个大脑。
That could be just connecting to the hand knob.
这可能只是连接到手柄。
You might have a lot of interesting interaction, human computer interaction possibilities.
你可能有很多有趣的交互、人机交互的可能性。
That’s really interesting.
这真的很有趣。
And the technology on the academic side is progressing at light speed here.
学术方面的技术在这里正在以光速进步。
4:43:22 There was a really amazing paper out of UC Davis at Sergey Stavisky’s lab that basically made an initial solve of speech decode.
加州大学戴维斯分校谢尔盖·斯塔维斯基实验室发表了一篇非常令人惊叹的论文,基本上解决了语音解码问题。
It was something like 125,000 words that they were getting with very high accuracy, which is-
他们以非常高的准确度获得了大约 125,000 个单词,即——
So you’re just thinking the word?
所以你只是在想这个词?
Yeah.
是的。
Thinking the word and you’re able to get it?
思考这个词,你就能明白吗?
Yeah.
是的。
Oh, boy.
哦,男孩。
4:43:51 You have to have the intention of speaking it.
你必须有说这句话的意图。
So do the inner voice.
内心的声音也是如此。
Man, it’s so amazing to me that you can do the intention, the signal mapping.
伙计,这对我来说太神奇了,你可以做意图,信号映射。
All you have to do is just imagine yourself doing it.
你所要做的只是想象你自己在做这件事。
And if you get the feedback that it actually worked, you can get really good at that.
如果你得到了它确实有效的反馈,你就可以在这方面做得非常好。
Your brain will first of all adjust and you develop, like any other skill, like touch typing.
你的大脑首先会进行调整,然后你就会得到发展,就像任何其他技能一样,比如盲打。
You develop in that same kind of way.
你也会以同样的方式发展。
4:44:24 To me, it’s just really fascinating to be able to even to play with that, honestly, I would get a Neuralink just to be able to play with that, just to play with the capacity, the capability of my mind to learn this skill.
对我来说,能够玩这个真的很有趣,老实说,我会得到一个 Neuralink 只是为了能够玩它,只是为了玩我的能力,我的大脑学习这项技能的能力。
It’s like learning the skill of typing and learning the skill of moving a mouse.
这就像学习打字的技巧和学习移动鼠标的技巧一样。
It’s another skill of moving the mouse, not with my physical body, but with my mind.
这是移动鼠标的另一个技巧,不是用我的身体,而是用我的思想。
I can’t wait to see what people do with it.
我迫不及待地想看看人们用它做什么。
4:44:47 I feel like we’re cavemen right now.
我觉得我们现在就像穴居人。
We’re banging rocks with a stick and thinking that we’re making music.
我们用棍子敲打岩石,并认为我们正在创作音乐。
At some point when these are more widespread, there’s going to be the equivalent of a piano that someone can make art with their brain in a way that we didn’t even anticipate.
当这些变得更加普遍时,就会出现相当于一架钢琴的东西,人们可以用他们的大脑以一种我们意想不到的方式创作艺术。
Looking forward to it.
期待它。
Give it to a teenager.
把它交给一个青少年。
4:45:12 Anytime I think I’m good at something I’ll always go to…
每当我认为自己擅长某件事时,我总是会去……
I don’t know.
我不知道。
Even with the bits per second and playing a video game, you realize you give it to a teenager, you give a Neuralink to a teenager.
即使每秒的比特数和玩电子游戏,你也会意识到你把它给了一个青少年,你把 Neuralink 给了一个青少年。
Just a large number of them, the kind of stuff they get good at stuff, they’re going to get hundreds of bits per second.
他们中的大量人员,他们擅长的东西,他们每秒将获得数百位。
Even just with the current technology.
即使仅以当前的技术。
Probably.
大概。
4:45:37 Probably.
大概。
Because it’s also addicting, the number go up aspect of it of improving and training.
因为它也会让人上瘾,所以改进和训练的数量会增加。
4:45:41 It is almost like a skill and plus there’s the software on the other end that adapts to you, and especially if the adapting procedure algorithm becomes better and better and better.
它几乎就像一种技能,而且另一端有适合您的软件,特别是如果适应过程算法变得越来越好的话。
You’re like learning together.
你们喜欢一起学习。
Yeah, we’re scratching the surface on that right now.
是的,我们现在正在触及这个问题的表面。
4:45:59 There’s so much more to do.
还有很多事情要做。
So on the complete other side of it, you have an RFID chip implanted in you?
那么在它的另一面,你体内植入了 RFID 芯片?
Yeah.
是的。
So I hear.
所以我听到了。
Nice.
好的。
So this is-
所以这是——
Little subtle thing.
小微妙的事情。
It’s a passive device that you use for unlocking a safe with top secrets or what do you use it for?
它是一种被动设备,用于解锁具有最高机密的保险箱,或者您用它做什么?
4:46:14 What’s the story behind it?
这背后的故事是什么?
I’m not the first one.
我不是第一个。
4:46:23 There’s this whole community of weirdo biohackers that have done this stuff, and I think one of the early use cases was storing private crypto wallet keys and whatever.
整个社区的怪异生物黑客都做了这些事情,我认为早期的用例之一是存储私人加密钱包密钥等。
I dabbled in that a bit and had some fun with it.
我涉足了一点并从中获得了一些乐趣。
You have some Bitcoin implanted in your body somewhere.
你的身体某处植入了一些比特币。
4:46:42 You can’t tell where.
你不知道在哪里。
Yeah, yeah.
是啊是啊。
Actually, yeah.
事实上,是的。
4:46:48 It was the modern day equivalent of finding change in the sofa cushions after I put some orphaned crypto on there that I thought was worthless and forgot about it for a few years.
这相当于现代的情况,就像我在沙发垫上放了一些我认为毫无价值并忘记了几年的孤立加密货币后,在沙发垫上找到了零钱。
Went back and found that some community of people loved it and had propped up the value of it, and so it had gone up fifty-fold, so there was a lot of change in those cushions.
回去发现有些人喜欢它,推高了它的价值,所以它涨了五十倍,所以那些垫子有很多变化。
That’s hilarious.
太搞笑了。
But the primary use case is mostly as a tech demonstrator.
但主要用例主要是作为技术演示者。
4:47:14 It has my business card on it.
上面有我的名片。
You can scan that in by touching it to your phone.
您可以通过将其触摸到手机来扫描它。
It opens the front door to my house, whatever, simple stuff.
它打开了我家的前门,无论如何,简单的东西。
It’s a cool step.
这是一个很酷的步骤。
4:47:30 It’s a cool leap to implant something in your body.
将某些东西植入你的身体是一个很酷的飞跃。
I mean, perhaps it’s a similar leap to a Neuralink because for a lot of people, that kind of notion of putting something inside your body, something electronic inside a biological system is a big leap.
我的意思是,也许这对 Neuralink 来说是一个类似的飞跃,因为对于很多人来说,将某种东西放入你的体内,将某种电子东西放入生物系统中的想法是一个巨大的飞跃。
We have a kind of mysticism around the barrier of our skin.
我们的皮肤屏障有一种神秘感。
4:47:45 We’re completely fine with knee replacements, hip replacements, dental implants, but there’s a mysticism still around the inviolable barrier that the skull represents, and I think that needs to be treated like any other pragmatic barrier.
我们完全同意膝关节置换术、髋关节置换术、牙科植入物,但头骨所代表的不可侵犯的屏障仍然存在一种神秘感,我认为需要像对待任何其他实用障碍一样对待它。
The question isn’t how incredible is it to open the skull?
问题不在于打开头骨有多不可思议?
The question is what benefit can we provide?
问题是我们能提供什么好处?
So from all the surgeries you’ve done, from everything you understand the brain, how much does neuroplasticity come into play?
那么,从你做过的所有手术来看,从你对大脑的了解来看,神经可塑性在多大程度上发挥了作用?
4:48:21 How adaptable is the brain?
大脑的适应性有多强?
For example, just even in the case of healing from surgery or adapting to the post-surgery situation.
例如,即使在手术愈合或适应手术后情况的情况下。
The answer that is sad for me and other people of my demographic is that plasticity decreases with age.
对于我和我的其他人来说,令人悲伤的答案是可塑性随着年龄的增长而下降。
4:48:36 Healing decreases with age.
随着年龄的增长,愈合能力会降低。
I have too much gray hair to be optimistic about that.
我的白发太多,对此不乐观。
There are theoretical ways to increase plasticity using electrical stimulation.
有一些理论上的方法可以利用电刺激来增加可塑性。
Nothing that is totally proven out as a robust enough mechanism to offer widely to people.
没有任何一种机制被完全证明是一种足够强大的机制,可以广泛地向人们提供服务。
4:49:06 But yeah, I think there’s cause for optimism that we might find something useful in terms of say, an implanted electrode that improves learning.
但是,是的,我认为我们有理由乐观,我们可能会发现一些有用的东西,比如可以改善学习的植入电极。
Certainly there’s been some really amazing work recently from Nicholas Schiff, Jonathan Baker and others who have a cohort of patients with moderate traumatic brain injury who have had electrodes placed in the deep nucleus in the brain called the central median nucleus or just near central median nucleus, and when they apply small amounts of electricity to that part of the brain, it’s almost like electronic caffeine.
当然,尼古拉斯·希夫(Nicholas Schiff)、乔纳森·贝克(Jonathan Baker)和其他人最近做了一些非常令人惊奇的工作,他们对一组患有中度创伤性脑损伤的患者进行了一些研究,这些患者将电极放置在大脑深部核中,称为中央正中核或靠近中央正中核,当他们向大脑的该部分施加少量电流时,它几乎就像电子咖啡因一样。
4:49:46 They’re able to improve people’s attention and focus.
它们能够提高人们的注意力和专注力。
They’re able to improve how well people can perform a task.
他们能够提高人们执行任务的能力。
I think in one case, someone who was unable to work, after the device was turned on, they were able to get a job.
我认为在一个案例中,那些无法工作的人,在设备打开后,他们能够找到工作。
And that’s sort of one of the holy grails for me with Neuralink and other technologies like this is from a purely utilitarian standpoint, can we make people able to take care of themselves and their families economically again?
对我来说,Neuralink 和其他类似技术的圣杯之一是从纯粹功利主义的角度来看,我们能让人们再次在经济上照顾自己和家人吗?
Can we make it so someone who’s fully dependent and even maybe requires a lot of caregiver resources, can we put them in a position to be fully independent, taking care of themselves, giving back to their communities?
我们能否让那些完全依赖他人、甚至可能需要大量护理资源的人,能够让他们完全独立、照顾自己、回馈社区?
I think that’s a very compelling proposition and what motivates a lot of what I do and what a lot of the people at Neuralink are working for.
我认为这是一个非常引人注目的主张,也是我所做的许多事情以及 Neuralink 的许多人正在为之努力的动力。
It’s just a cool possibility that if you put a Neuralink in there, that the brain adapts the other part of the brain adapts too and integrates it.
这是一个很酷的可能性,如果你把 Neuralink 放在那里,大脑就会适应大脑的其他部分也会适应并整合它。
4:50:45 The capacity of the brain to do that is really interesting.
大脑做到这一点的能力真的很有趣。
Probably unknown to the degree to which you can do that, but you’re now connecting an external thing to it, especially once it’s doing stimulation.
可能不知道你能做到什么程度,但你现在正在将一个外部事物与其连接起来,尤其是当它进行刺激时。
The biological brain and the electronic brain outside of it working together, the possibilities there are really interesting.
生物大脑和外面的电子大脑一起工作,那里的可能性真的很有趣。
It’s still unknown, but interesting.
这仍然是未知的,但很有趣。
It feels like the brain is really good at adapting to whatever, but of course it is a system that by itself is already, everything serves a purpose and so you don’t want to mess with it too much.
感觉大脑真的很擅长适应任何事情,但当然,它本身就是一个系统,一切都有其目的,所以你不想过多地干扰它。
Yeah, it’s like eliminating a species from an ecology.
是的,这就像从生态系统中消除一个物种。
4:51:39 You don’t know what the delicate interconnections and dependencies are.
你不知道微妙的相互联系和依赖是什么。
The brain is certainly a delicate, complex beast, and we don’t know every potential downstream consequence of a single change that we make.
大脑无疑是一只精致、复杂的野兽,我们不知道我们所做的单个改变的每一个潜在的下游后果。
Do you see yourself doing, so you mentioned P1, surgeries of P2, P3, P4, P5?
你认为你自己在做什么,所以你提到了P1,P2,P3,P4,P5的手术?
4:52:04 Just more and more and more humans.
只是越来越多的人类。
I think it’s a certain kind of brittleness or a failure on the company’s side if we need me to do all the surgeries.
我认为如果我们需要我做所有的手术,这就是公司方面的某种脆弱性或失败。
4:52:14 I think something that I would very much like to work towards is a process that is so simple and so robust on the surgery side that literally anyone could do it.
我认为我非常希望努力实现的一个过程在手术方面非常简单且强大,几乎任何人都可以做到。
We want to get away from requiring intense expertise or intense experience to have this done and make it as simple and translatable as possible.
我们希望摆脱需要大量专业知识或丰富经验来完成这项工作,并使其尽可能简单和可翻译。
I mean, I would love it if every neurosurgeon on the planet had no problem doing this.
我的意思是,如果地球上的每个神经外科医生都能毫无问题地做到这一点,我会很高兴。
I think we’re probably far from a regulatory environment that would allow people that aren’t neurosurgeons to do this, but not impossible.
我认为我们可能距离允许非神经外科医生这样做的监管环境还很远,但并非不可能。
All right, I’ll sign up for that.
好吧,我会报名的。
4:53:08 Did you ever anthropomorphize the robot R1?
你曾经把机器人R1拟人化过吗?
Do you give it a name?
你给它起个名字吗?
Do you see it as a friend as working together with you?
您是否将与您一起工作视为朋友?
I mean, to a certain degree it’s-
我的意思是,在某种程度上——
Or an enemy who’s going to take your job?
或者是一个要抢走你工作的敌人?
To a certain degree, yeah.
在某种程度上,是的。
4:53:25 It’s complex relationship.
这是一个复杂的关系。
All the good relationships are.
所有良好的关系都是如此。
It’s funny when in the middle of the surgery, there’s a part of it where I stand basically shoulder to shoulder with the robot, and so if you’re in the room reading the body language, it’s my brother in arms there.
有趣的是,在手术过程中,有一部分我基本上与机器人肩并肩站着,所以如果你在房间里阅读肢体语言,那就是我的兄弟。
4:53:32 We’re working together on the same problem.
我们正在共同解决同一个问题。
Yeah, I’m not threatened by it.
是的,我没有受到它的威胁。
Keep telling yourself that.
不断这样告诉自己。
4:53:55 How have all the surgeries that you’ve done over the years, the people you’ve helped and the stakes, the high stakes that you’ve mentioned, how has that changed your understanding of life and death?
这些年来你做过的所有手术、你帮助过的人以及你提到的风险、高风险,这些如何改变了你对生与死的理解?
Yeah, it gives you a very visceral sense, and this may sound trite, but it gives you a very visceral sense that death is inevitable.
是的,它给你一种非常本能的感觉,这可能听起来很老套,但它给你一种非常本能的感觉,死亡是不可避免的。
4:54:13 On one hand, as a neurosurgeon, you’re deeply involved in these, just hard to fathom tragedies, young parents dying, leaving a four-year-old behind, say.
一方面,作为一名神经外科医生,你深深地卷入了这些难以理解的悲剧,比如年轻的父母去世,留下一个四岁的孩子。
And on the other hand, it takes the sting out of it a bit because you see how just mind-numbingly universal death is.
另一方面,它减轻了一点刺痛,因为你看到普遍的死亡是多么令人麻木。
There’s zero chance that I’m going to avoid it.
我避免它的可能性为零。
I know techno-optimists right now and longevity buffs right now would disagree on that 0.000% estimate, but I don’t see any chance that our generation is going to avoid it.
我知道现在的技术乐观主义者和长寿爱好者不会同意 0.000% 的估计,但我不认为我们这一代人有任何机会避免它。
Entropy is a powerful force and we are very ornate, delicate, brittle, DNA machines that aren’t up to the cosmic ray bombardment that we’re subjected to.
熵是一种强大的力量,而我们是非常华丽、精致、脆弱的 DNA 机器,无法承受我们所遭受的宇宙射线轰击。
4:55:35 So on the one hand, every human that has ever lived died or will die.
因此,一方面,每一个曾经活过的人都已经死亡或将要死亡。
On the other hand, it’s just one of the hardest things to imagine inflicting on anyone that you love is having them gone.
另一方面,让你所爱的人离开是最难想象的事情之一。
I mean, I’m sure you’ve had friends that aren’t living anymore and it’s hard to even think about them.
我的意思是,我确信你有一些朋友已经去世了,甚至很难去想他们。
And so I wish I had arrived at the point of nirvana where death doesn’t have a sting, I’m not worried about it.
所以我希望我已经到达了涅槃,死亡不再有刺痛,我并不担心。
But I can at least say that I’m comfortable with the certainty of it, if not having found out how to take the tragedy out of it.
但我至少可以说,即使我没有找到如何消除悲剧的方法,我也对它的确定性感到满意。
When I think about my kids either not having me or me not having them or my wife.
当我想到我的孩子要么没有我,要么我没有他们或我的妻子时。
Maybe I’ve come to accept the intellectual certainty of it, but it may be the pain that comes with losing the people you love.
也许我已经接受了它在理智上的确定性,但这可能是失去你所爱的人带来的痛苦。
4:56:35 But I don’t think I’ve come to understand the existential aspect of it, that this is going to end, and I don’t mean in some trite way.
但我不认为我已经理解了它存在的一面,这一切即将结束,我的意思并不是以某种陈词滥调的方式。
I mean, it certainly feels like it’s not going to end.
我的意思是,它确实感觉它不会结束。
You live life like it’s not going to end.
你的生活就像它不会结束一样。
And the fact that this light that’s shining, this consciousness is going to no longer be in one moment, maybe today.
事实上,这种闪耀的光、这种意识将在某一刻(也许今天)不再存在。
It fills me when I really am able to load all that in with Ernest Becker’s terror.
当我真正能够将这一切与欧内斯特·贝克尔的恐怖联系在一起时,我感到很充实。
It is a real fear.
这是一种真正的恐惧。
4:57:28 I think people aren’t always honest with how terrifying it is.
我认为人们并不总是诚实地意识到它有多么可怕。
I think the more you are able to really think through it, the more terrifying it is.
我想你越能真正思考它,它就越可怕。
It’s not such a simple thing, “Oh, well, it’s the way life is.” If you really can load that in, it’s hard, but I think that’s why the Stoics did it, because it helps you get your shit together and be like, “The moment, every single moment you’re alive is just beautiful” and it’s terrifying that it’s going to end, and it’s almost like you’re shivering in the cold, a child helpless.
这不是一件简单的事情,“哦,好吧,生活就是这样。”如果你真的能把它加载进去,那就很难了,但我认为这就是斯多葛学派这么做的原因,因为它可以帮助你整理好心情,然后说,“那一刻,你活着的每一刻都是美丽的”,而它即将结束是可怕的,这几乎就像你在寒冷中瑟瑟发抖,一个无助的孩子。
This kind of feeling,
这种感觉,
4:58:10 And then it makes you, when you have warmth, when you have the safety, when you have the love to really appreciate it.
然后,当你有温暖、有安全、有爱时,它会让你真正感激它。
I feel like sometimes in your position when you mentioned armor just to see death, it might make you not be able to see that, the finiteness of life because if you kept looking at that, it might break you.
我觉得有时在你的立场上,当你提到盔甲只是为了看到死亡时,它可能会让你看不到生命的有限性,因为如果你一直看着它,它可能会让你崩溃。
So it is good to know that you’re kind of still struggling with that.
所以很高兴知道您仍在为此苦苦挣扎。
There’s the neurosurgeon and then there’s a human, and the human is still able to struggle with that and feel the fear of that and the pain of that.
有神经外科医生,然后有一个人,而人类仍然能够与之斗争,感受到对此的恐惧和痛苦。
Yeah, it definitely makes you ask the question of how many of these can you see and not say, “I can’t do this anymore”?
是的,这肯定会让你问这样的问题:你能看到其中有多少,而不是说“我不能再这样做了”?
4:58:51 But I mean you said it well, I think it gives you an opportunity to just appreciate that you’re alive today and I’ve got three kids and an amazing wife, and I am really happy.
但我的意思是你说得很好,我认为这让你有机会欣赏你今天还活着,我有三个孩子和一个很棒的妻子,我真的很高兴。
Things are good.
事情很好。
I get to help on a project that I think matters.
我可以为一个我认为重要的项目提供帮助。
I think it moves us forward.
我认为它推动我们前进。
I’m a very lucky person.
我是一个非常幸运的人。
It’s the early steps of a potentially gigantic leap for humanity.
这是人类潜在的巨大飞跃的早期步骤。
4:59:30 It’s a really interesting one.
这真的很有趣。
And it’s cool because you read about all this stuff in history where it’s like the early days.
这很酷,因为你读到了历史上所有这些东西,就像早期的那样。
I’ve been reading, before going to the Amazon, I would read about explorers that would go and explore even the Amazon jungle for the first time.
在去亚马逊之前,我一直在阅读有关探险家的文章,他们甚至会第一次去探索亚马逊丛林。
It’s just those are the early steps or early steps into space, early steps in any discipline in physics and mathematics, and it’s cool because on the grand scale, these are the early steps into delving deep into the human brain, so not just observing the brain but be able to interact with the human brain.
这些只是进入太空的早期步骤,是物理和数学任何学科的早期步骤,这很酷,因为从大范围来看,这些是深入研究人脑的早期步骤,因此不仅仅是观察大脑,而且能够与人脑互动。
It’s going to help a lot of people, but it also might help us understand what the hell’s going on in there.
它会帮助很多人,但也可能帮助我们了解那里到底发生了什么。
Yeah.
是的。
5:00:20 I think ultimately we want to give people more levers that they can pull.
我认为最终我们希望为人们提供更多可以拉动的杠杆。
You want to give people options.
你想给人们选择。
If you can give someone a dial that they can turn on how happy they are, I think that makes people really uncomfortable.
如果你可以给某人一个旋钮,让他们可以打开他们的幸福程度,我认为这会让人们感到非常不舒服。
But now talk about major depressive disorder.
但现在谈谈重度抑郁症。
Talk about people that are committing suicide at an alarming rate in this country, and try to justify that queasiness in that light of, you can give people a knob to take away suicidal ideation, suicidal intention.
谈论这个国家正在以惊人的速度自杀的人,并试图证明这种恶心是合理的,因为你可以给人们一个旋钮来消除自杀意念、自杀意图。
I would give them that knob.
我会给他们那个旋钮。
I don’t know how you justify not doing that.
我不知道你如何证明不这样做。
You can think about all the suffering that’s going on in the world, every single human being that’s suffering right now.
你可以想想世界上正在发生的所有苦难,每个人现在都在受苦。
5:01:11 It’ll be a glowing red dot.
它将是一个发光的红点。
The more suffering, the more it’s glowing, and you just see the map of human suffering and any technology that allows you to dim that light of suffering on a grand scale is pretty exciting.
苦难越多,它就越发光,你只能看到人类苦难的地图,任何可以让你大规模调暗苦难之光的技术都是非常令人兴奋的。
Because there’s a lot of people suffering and most of them suffer quietly, and we look away too often, and we should remember those are suffering because once again, most of them are suffering quietly.
因为有很多人在受苦,而且大多数人都在默默地受苦,我们经常把目光移开,我们应该记住那些正在受苦的人,因为他们中的大多数人再次在默默地受苦。
Well, and on a grander scale, the fabric of society.
嗯,从更宏观的角度来看,是社会结构。
5:01:46 People have a lot of complaints about how our social fabric is working or not working, how our politics is working or not working.
人们对我们的社会结构如何运作或不运作、我们的政治如何运作或不运作有很多抱怨。
Those things are made of neurochemistry too in aggregate, right?
这些东西总体上也是由神经化学组成的,对吗?
Our politics is composed of individuals with human brains, and the way it works or doesn’t work is potentially tunable in the sense that, I don’t know, say remove our addictive behaviors or tune our addictive behaviors for social media or our addiction to outrage, our addiction to sharing the most angry political tweet we can find.
我们的政治是由具有人类大脑的个人组成的,它的运作或不运作的方式可能是可以调整的,我不知道,比如说消除我们的成瘾行为,或者调整我们对社交媒体的成瘾行为,或者我们对愤怒的成瘾,我们对分享我们能找到的最愤怒的政治推文的成瘾。
I don’t think that leads to a functional society, and if you had options for people to moderate that maladaptive behavior, there could be huge benefits to society.
我不认为这会带来一个功能正常的社会,如果人们有选择来调节这种适应不良的行为,那么可能会给社会带来巨大的好处。
Maybe we could all work together a little more harmoniously toward useful ends.
也许我们可以更加和谐地合作,以实现有益的目标。
There’s a sweet spot, like you mentioned.
正如你提到的,有一个最佳点。
5:03:00 You don’t want to completely remove all the dark sides of human nature.
你不想完全消除人性的所有阴暗面。
Those are somehow necessary to make the whole thing work, but there’s a sweet spot.
这些对于整个事情的顺利进行来说是必要的,但有一个最佳点。
Yeah, I agree.
是的,我同意。
5:03:11 You got to suffer a little, just not so much that you lose hope.
你必须承受一点痛苦,但不要痛苦到失去希望。
Yeah.
是的。
5:03:16 When you, all the surgeries you’ve done, have you seen consciousness in there ever?
当你,你做过的所有手术中,你见过意识吗?
Was there a glowing light?
有发光吗?
I have this sense that I never found it, never removed it like a Dementor in Harry Potter.
我有一种感觉,我从来没有找到过它,也没有像《哈利·波特》中的摄魂怪那样将它移除。
5:03:22 I have this sense that consciousness is a lot less magical than our instincts want to claim it is.
我有这样的感觉:意识远没有我们的本能所宣称的那么神奇。
It seems to me like a useful analog for about what consciousness is in the brain is that we have a really good intuitive understanding of what it means to say, touch your skin and know what’s being touched.
在我看来,关于大脑中意识的一个有用的类比是,我们对触摸你的皮肤并知道所触摸的是什么有很好的直观理解。
And I think consciousness is just that level of sensory mapping applied to the thought processes in the brain itself.
我认为意识只是应用于大脑本身思维过程的感觉映射水平。
5:04:10 So what I’m saying is, consciousness is the sensation of some part of your brain being active, so you feel it working.
所以我想说的是,意识是你大脑某些部分活跃的感觉,所以你感觉它在工作。
You feel the part of your brain that thinks of red things or winged creatures or the taste of coffee.
你感觉到大脑中负责思考红色物体、带翅膀的生物或咖啡味道的部分。
You feel those parts of your brain being active, the way that I’m feeling my palm being touched, and that sensory system that feels the brain working is consciousness.
你会感觉到大脑的那些部分正在活跃,就像我感觉到我的手掌被触摸一样,而感觉大脑正在工作的感觉系统就是意识。
That’s so brilliant.
太棒了。
5:04:43 It’s the same way.
都是一样的。
It’s the sensation of touch when you’re touching a thing.
这是当你触摸某物时的触觉。
Consciousness is the sensation of you feeling your brain working, your brain thinking, your brain perceiving.
意识是你感觉到你的大脑在工作、你的大脑思考、你的大脑感知的感觉。
Which isn’t like a warping of space-time or some quantum field effect, right?
这不像时空扭曲或某种量子场效应,对吧?
5:04:59 It’s nothing magical.
这没什么神奇的。
People always want to ascribe to consciousness something truly different, and there’s this awesome long history of people looking at whatever the latest discovery in physics is to explain consciousness because it’s the most magical, the most out there thing that you can think of, and people always want to do that with consciousness.
人们总是想把一些真正不同的东西归因于意识,而且有一段令人敬畏的悠久历史,人们一直在寻找物理学的最新发现来解释意识,因为它是你能想到的最神奇、最外在的东西,而且人们总是想用意识来做到这一点。
I don’t think that’s necessary.
我认为没有必要。
It’s just a very useful and gratifying way of feeling your brain work.
这是感受大脑工作的一种非常有用且令人满意的方式。
And as we said, it’s one heck of a brain.
正如我们所说,这是一个非常棒的大脑。
5:05:38 Everything we see around us, everything we love, everything that’s beautiful came from brains like these.
我们周围看到的一切、我们所爱的一切、一切美丽的东西都来自这样的大脑。
It’s all electrical activity happening inside your skull.
这都是你头骨内发生的电活动。
And I, for one, am grateful there’s people like you that are exploring all the ways that it works and all the ways it can be made better.
就我而言,我很感激像您这样的人正在探索它的所有运作方式以及所有可以使其变得更好的方式。
Thanks, Lex.
谢谢,莱克斯。
Thank you so much for talking today.
非常感谢您今天的发言。
It’s been a joy.
这是一种快乐。
Thanks for listening to this conversation with Matthew MacDougall.
感谢您收听与马修·麦克杜格尔的对话。
5:06:08 Now, dear friends, here’s Bliss Chapman, brain interface software lead at Neuralink.
现在,亲爱的朋友们,这是 Neuralink 大脑接口软件负责人布利斯·查普曼 (Bliss Chapman)。
You told me that you’ve met hundreds of people with spinal cord injuries or with ALS, and that your motivation for helping at Neuralink is grounded in wanting to help them.
您告诉我,您见过数百名脊髓损伤或 ALS 患者,您在 Neuralink 提供帮助的动机是出于想要帮助他们。
Can you describe this motivation?
你能描述一下这个动机吗?
Yeah.
是的。
5:06:32 First, just a thank you to all the people I’ve gotten a chance to speak with for sharing their stories with me.
首先,感谢所有有机会与我交谈的人与我分享他们的故事。
I don’t think there’s any world really in which I can share their stories as powerful way as they can, but just I think to summarize at a very high level, what I hear over and over again is that people with ALS or severe spinal cord injury in a place where they basically can’t move physically anymore, really at the end of the day are looking for independence.
我认为没有哪个世界真的能让我像他们一样有力地分享他们的故事,但我想在一个非常高的层面上总结一下,我一遍又一遍地听到的是,患有 ALS 或严重脊髓损伤的人在身体上基本上无法再移动,最终真的在寻求独立。
And that can mean different things for different people.
这对于不同的人来说可能意味着不同的事情。
5:07:02 For some folks, it can mean the ability just to be able to communicate again independently without needing to wear something on their face, without needing a caretaker to be able to put something in their mouth.
对于一些人来说,这可能意味着能够再次独立交流,而不需要在脸上戴东西,不需要看护者能够把东西放进嘴里。
For some folks, it can mean independence to be able to work again, to be able to navigate a computer digitally, efficiently enough to be able to get a job, to be able to support themselves, to be able to move out and ultimately be able to support themselves after their family maybe isn’t there anymore to take care of them.
对于一些人来说,这可能意味着独立,能够再次工作,能够以数字方式操作计算机,足够高效地找到工作,能够养活自己,能够搬出去,并最终能够在家人可能不再照顾他们后养活自己。
5:07:27 And for some folks, it’s as simple as just being able to respond to their kid in time before they run away or get interested in something else.
对于一些人来说,这就像在孩子逃跑或对其他事情感兴趣之前及时回应他们一样简单。
And these are deeply personal and very human problems.
这些都是非常个人化、非常人性化的问题。
And what strikes me again and again when talking with these folks is that this is actually an engineering problem.
当与这些人交谈时,让我一次又一次震惊的是,这实际上是一个工程问题。
This is a problem that with the right resources, with the right team, can make a lot of progress on.
只要有合适的资源和合适的团队,这个问题就可以取得很大进展。
And at the end of the day, I think that’s a deeply inspiring message and something that makes me excited to get up every day.
归根结底,我认为这是一个非常鼓舞人心的信息,让我每天都兴奋地起床。
So it’s both an engineering problem in terms of a BCI, for example, that can give them capabilities where they can interact with the world, but also on the other side, it’s an engineering problem for the rest of the world to make it more accessible for people living with quadriplegia?
因此,这既是脑机接口方面的一个工程问题,例如,它可以赋予他们与世界互动的能力,但另一方面,对于世界其他地方来说,让四肢瘫痪的人更容易使用它也是一个工程问题?
Yeah.
是的。
5:08:15 And actually, I’ll take a broad view lens on this for a second.
事实上,我会用更广泛的视角来看待这个问题。
I think I’m very in favor of anyone working in this problem space.
我认为我非常支持任何在这个问题领域工作的人。
So beyond BCI, I’m happy and excited and willing to support any way I can, folks working on eye tracking systems, working on speech to text systems, working on head trackers or mouse sticks or quad sticks.
因此,除了 BCI 之外,我很高兴、很兴奋,并且愿意尽我所能支持那些从事眼球追踪系统、语音转文本系统、头部追踪器、鼠标棒或四边形摇杆工作的人们。
And I’ve met many engineers and folks in the community that do exactly those things.
我在社区中遇到了许多工程师和人们,他们正是做这些事情的。
5:08:38 And I think for the people we’re trying to help, it doesn’t matter what the complexity of the solution is as long as the problem is solved.
我认为对于我们试图帮助的人来说,只要问题得到解决,解决方案的复杂性并不重要。
And I want to emphasize that there can be many solutions out there that can help with these problems.
我想强调的是,有很多解决方案可以帮助解决这些问题。
And BCI is one of a collection of such solutions.
BCI 就是此类解决方案的集合之一。
So BCI in particular, I think offers several advantages here.
我认为特别是 BCI 在这方面提供了几个优势。
And I think the folks that recognize this immediately are usually the people who have spinal cord injury or some form of paralysis.
我认为立即意识到这一点的人通常是那些患有脊髓损伤或某种形式瘫痪的人。
5:09:03 Usually you don’t have to explain to them why this might be something that could be helpful.
通常你不必向他们解释为什么这可能会有帮助。
It’s usually pretty self-evident, but for the rest of us folks that don’t live with severe spinal cord injury or who don’t know somebody with ALS, it’s not often obvious why you would want a brain implant to be able to connect and navigate a computer.
这通常是不言而喻的,但对于我们这些没有严重脊髓损伤或不认识 ALS 患者的人来说,为什么想要大脑植入物能够连接和导航计算机通常并不明显。
5:09:18 And it’s surprisingly nuanced, and to the degree that I’ve learned a huge amount just working with Noland in the first Neuralink clinical trial and understanding from him and his words why this device is impactful for him, and it’s a nuanced topic.
它的微妙之处令人惊讶,在某种程度上,我在第一次 Neuralink 临床试验中与 Noland 合作并从他和他的话中了解了为什么这个设备对他有影响,并且这是一个微妙的话题。
It can be the case that even if you can achieve the same thing, for example, with a mouse stick when navigating a computer, he doesn’t have access to that mouse stick every single minute of the day.
可能的情况是,即使你可以实现同样的目标,例如,在浏览计算机时使用鼠标杆,他也无法在一天中的每一分钟都使用该鼠标杆。
He only has access when someone is available to put it in front of him.
只有当有人可以将其放在他面前时,他才可以访问。
And so a BCI can really offer a level of independence and autonomy that, if it wasn’t literally physically part of your body, it’d be hard to achieve in any other way.
因此,脑机接口确实可以提供一定程度的独立性和自主性,如果它实际上不是您身体的一部分,则很难通过任何其他方式实现。
So there’s a lot of fascinating aspects to what it takes to get Noland to be able to control a cursor on the screen with his mind.
因此,让诺兰能够用意念控制屏幕上的光标需要有很多令人着迷的方面。
5:09:52 You texted me something that I just love.
你给我发了一条我很喜欢的短信。
You said, “I was part of the team that interviewed and selected P1, I was in the operating room during the first human surgery monitoring live signals coming out of the brain.
你说,“我是面试和选择 P1 的团队的一员,在第一次人体手术期间我在手术室里监测来自大脑的实时信号。
I work with the user basically every day to develop new UX paradigms, decoding strategies, and I was part of the team that figured out how to recover useful BCI to new world record levels when the signal quality degraded.” We’ll talk about, I think every aspect of that, but just zooming out, what was it like to be a part of that team and part of that historic, I would say, historic first?
我基本上每天都与用户一起开发新的 UX 范式、解码策略,并且我是团队的一员,该团队研究了如何在信号质量下降时将有用的 BCI 恢复到新的世界纪录水平。”我们将讨论,我认为这的各个方面,但只是缩小范围,成为该团队的一部分以及我想说的历史性第一的一部分是什么感觉?
Yeah.
是的。
5:10:38 I think for me, this is something I’ve been excited about for close to 10 years now.
我想对我来说,这是近十年来我一直兴奋的事情。
And so to be able to be even just some small part of making it a reality is extremely exciting.
因此,即使只是成为现实的一小部分,也是非常令人兴奋的。
A couple maybe special moments during that whole process that I’ll never really truly forget.
在整个过程中,有几个可能是我永远不会真正忘记的特殊时刻。
One of them is entering the actual surgery.
其中之一正在进入实际手术。
At that point in time, I know Noland quite well.
那时我对诺兰已经很了解了。
I know his family.
我认识他的家人。
And so I think the initial reaction when Noland is rolled into the operating room is just an “Oh, shit” kind of reaction.
所以我认为当诺兰被推进手术室时,最初的反应只是“哦,该死”的反应。
But at that point, muscle memory kicks in and you sort of go into, you let your body just do all the talking.
但在那一刻,肌肉记忆开始发挥作用,你就开始让你的身体来说话。
5:11:19 And I have the lucky job in that particular procedure to just be in charge of monitoring the implant.
我很幸运能在那个特定的手术中负责监控植入物。
So my job is to sit there, to look at the signals coming off the implant, to look at the live brain data streaming off the device as threads are being inserted into the brain and just to basically observe and make sure that nothing is going wrong or that there’s no red flags or fault conditions that we need to go and investigate or pause the surgery to debug.
所以我的工作就是坐在那里,观察植入物发出的信号,观察当线程被插入大脑时从设备流出的实时大脑数据,基本上观察并确保没有任何问题,或者不存在需要我们去调查或暂停手术进行调试的危险信号或故障情况。
5:11:40 And because I had that sort of spectator view of the surgery, I had a slightly removed perspective than I think most folks in the room.
因为我对手术有一种旁观者的视角,所以我的视角比我想象的房间里的大多数人稍微遥远。
I got to sit there and think to myself, “Wow, that brain is moving a lot.” When you look inside the craniectomy that we stick the threads in, one thing that most people don’t realize is the brain moves.
我必须坐在那里心里想,“哇,那个大脑运转得很好。”当你观察我们插入线的颅骨切除术内部时,大多数人没有意识到的一件事是大脑在移动。
The brain moves a lot when you breathe, your heart beats, and you can see it visibly.
当你呼吸、心跳时,大脑会大量移动,你可以肉眼看到。
So that’s something that I think was a surprise to me and very, very exciting to be able to see someone’s brain who you physically know and have talked with that length, actually pausing and moving inside their skull.
所以我认为这对我来说是一个惊喜,而且非常非常令人兴奋能够看到一个你认识的人的大脑,并且已经谈论过那么长的时间,实际上在他们的头骨内暂停和移动。
And they used that brain to talk to you previously, and now it’s right there moving.
他们以前用那个大脑和你说话,现在它就在那里移动。
Yep.
是的。
Actually, I didn’t realize that in terms of the thread sending, so the Neuralink implant is active during surgery and one thread at a time, you’re able to start seeing the signal?
实际上,我没有意识到就线程发送而言,因此 Neuralink 植入物在手术期间处于活动状态,并且一次一个线程,您能够开始看到信号吗?
Yeah.
是的。
So that’s part of the way you test that the thing is working?
那么这是你测试该东西是否正常工作的方式的一部分?
Yeah.
是的。
5:12:35 So actually in the operating room, right after we sort of finished all the thread insertions, I started collecting what’s called broadband data.
所以实际上在手术室里,就在我们完成所有线程插入之后,我开始收集所谓的宽带数据。
So broadband is basically the most raw form of signal you can collect from a Neuralink electrode.
因此,宽带基本上是您可以从 Neuralink 电极收集的最原始的信号形式。
It’s essentially a measurement of the local fuel potential or the voltage essentially measured by that electrode.
它本质上是对局部燃料电势或由该电极测量的电压的测量。
And we have a certain mode in our application that allows us to visualize where detected spikes are.
我们的应用程序中有一种特定的模式,可以让我们可视化检测到的尖峰的位置。
So it visualizes where in the broadband signal and it’s very, very raw form of the data, a neuron is actually spiking.
因此,它可以可视化宽带信号及其非常原始的数据形式中神经元实际上在什么地方出现尖峰。
And so one of these moments that I’ll never forget as part of this whole clinical trial is seeing live in the operating room while he’s still under anesthesia, beautiful spikes being shown in the application, just streaming live to a device I’m holding in my hand.
因此,作为整个临床试验的一部分,我永远不会忘记的时刻之一是在手术室中看到他仍处于麻醉状态时的现场直播,应用程序中显示出美丽的尖峰,只是将直播传输到我手中的设备上。
So this is no signal processing the raw data, and then the signals processing is on top of it, you’re seeing the spikes detected?
所以这不是对原始数据进行信号处理,然后是在其之上进行信号处理,您看到检测到的尖峰了吗?
Right.
正确的。
And that’s a UX too, that looks beautiful as well.
这也是一种用户体验,看起来也很漂亮。
During that procedure, there was actually a lot of cameramen in the room, so they also were curious and wanted to see, there’s several neurosurgeons in the room who were all just excited to see robots taking their job, and they were all crowded around a small little iPhone watching this live brain data stream out of his brain.
在那个手术过程中,房间里实际上有很多摄影师,所以他们也很好奇,想看看,房间里有几个神经外科医生都很兴奋看到机器人取代他们的工作,他们都围在一个小小的 iPhone 周围,看着这些实时的大脑数据从他的大脑中流出。
What was that like seeing the robot do some of the surgery?
看到机器人做一些手术是什么感觉?
5:13:51 So the computer vision aspect where it detects all the spots that avoid the blood vessels, and then obviously with the human supervision, then actually doing the really high precision connection of the threads to the brain?
那么计算机视觉方面,它会检测所有避开血管的点,然后显然是在人类的监督下,然后实际上将线程与大脑进行真正高精度的连接?
That’s a good question.
这是一个好问题。
5:14:11 My answer is going to be pretty lame here, but it was boring.
我的回答在这里会很蹩脚,但很无聊。
I’ve seen it so many times.
我已经看过很多次了。
The way you want it to be.
你想要的方式。
Yeah, that’s exactly how you want surgery to be.
是的,这正是您想要的手术方式。
5:14:17 You want it to be boring.
你想让它变得无聊。
I’ve seen it so many times.
我已经看过很多次了。
I’ve seen the robot do the surgery literally hundreds of times, and so it was just one more time.
我已经见过机器人做手术数百次了,所以这只是再一次。
Yeah, all the practice surgeries and the proxies, and this is just another day.
是的,所有的练习手术和代理,这只是又一天。
Yeah.
是的。
So what about when Noland woke up?
那么诺兰醒来之后呢?
5:14:35 Do you remember a moment where he was able to move the cursor, not move the cursor, but get signal from the brain such that it was able to show that there’s a connection?
你还记得他能够移动光标的那一刻吗?不是移动光标,而是从大脑获得信号,从而能够表明存在联系?
Yeah.
是的。
5:14:49 Yeah.
是的。
So we are quite excited to move as quickly as we can, and Noland was really, really excited to get started.
因此,我们非常高兴能尽快采取行动,诺兰也非常非常兴奋能够开始。
He wanted to get started, actually the day of surgery, but we waited until the next morning very patiently.
他想开始,实际上是手术当天,但我们非常耐心地等到了第二天早上。
It’s a long night.
这是一个漫长的夜晚。
5:15:00 …
……
we waited until the next morning very patiently.
我们非常耐心地等到了第二天早上。
So a long night.
就这样度过了一个漫长的夜晚。
And the next morning in the ICU where he was recovering, he wanted to get started and actually start to understand what kind of signal we can measure from his brain.
第二天早上,在他康复的重症监护室里,他想开始真正了解我们可以从他的大脑中测量到什么样的信号。
And maybe for folks who are not familiar with the Neuralink system, we implant the Neuralink system or the Neuralink implant in the motor cortex.
也许对于那些不熟悉 Neuralink 系统的人来说,我们将 Neuralink 系统或 Neuralink 植入物植入运动皮层。
So the motor cortex is responsible for representing things like motor intent.
因此,运动皮层负责表示运动意图等事物。
If you imagine closing and opening your hand, that kind of signal representation would be present in the motor cortex.
如果你想象握紧和张开你的手,这种信号表示就会出现在运动皮层中。
5:15:31 If you imagine moving your arm back and forth or wiggling a pinky, this sort of signal can be present in the motor cortex.
如果你想象来回移动手臂或摆动小指,这种信号可能会出现在运动皮层中。
So one of the ways we start to map out what kind of signal do we actually have access to, in any particular individual’s brain, is through this task called body mapping.
因此,我们开始绘制出在任何特定个体的大脑中我们实际上可以获得什么样的信号的方法之一就是通过这项称为身体绘图的任务。
And body mapping is where you essentially present a visual to the user and you say, “Hey, imagine doing this,” and their visual is a 3D hand opening, closing or index finger modulating up and down.
身体映射本质上是向用户呈现视觉效果,然后你说,“嘿,想象一下这样做”,他们的视觉效果是 3D 手张开、合拢或食指上下调节。
5:15:55 And you ask the user to imagine that, and obviously you can’t see them do this, because they’re paralyzed, so you can’t see them actually move their arm.
你让用户想象一下,显然你看不到他们这样做,因为他们瘫痪了,所以你看不到他们实际移动手臂。
But while they do this task, you can record neural activity and you can basically offline model and check, “Can I predict, or can I detect the modulation corresponding with those different actions?” And so we did that task and we realized, “Hey, there’s actually some modulation associated with some of his hand motion,” which was a first indication that, “okay, we can potentially use that modulation to do useful things in the world.” For example, control a computer cursor.
但是,当他们执行此任务时,您可以记录神经活动,并且基本上可以离线建模并检查,“我可以预测,或者我可以检测与这些不同动作相对应的调制吗?”所以我们完成了这项任务,我们意识到,“嘿,实际上有一些与他的一些手部动作相关的调制”,这是第一个迹象,“好吧,我们可以利用这种调制在世界上做有用的事情。”例如,控制计算机光标。
5:16:24 And he started playing with it, the first time we showed him it.
当我们第一次向他展示它时,他就开始玩它。
And we actually just took the same live view of his brain activity and put it in front of him and we said, “Hey, you tell us what’s going on?
实际上,我们只是拍摄了他大脑活动的相同实时视图并将其放在他面前,我们说:“嘿,你告诉我们发生了什么事?
We’re not you.
我们不是你。
You’re able to imagine different things, and we know that it’s modulating some of these neurons, so you figure out for us, what that is actually representing.” And so he played with it for a bit.
你能够想象不同的事物,我们知道它正在调节其中一些神经元,所以你可以为我们弄清楚它实际上代表什么。”所以他玩了一会儿。
He was like, “I don’t quite get it yet.” He played for a bit longer and he said, “Oh, when I move this finger, I see this particular neuron start to fire more.”
他说:“我还没完全明白。”他玩了一会儿,然后说道:“哦,当我移动这个手指时,我看到这个特定的神经元开始更加活跃。”
5:16:51 And I said, “Okay, prove it.
我说:“好吧,证明一下。
Do it again.” And so he said, “Okay, three, two, one,” boom.
再做一次。”所以他说,“好吧,三,二,一,”繁荣。
And the minute he moved, you can see instantaneously this neuron is firing, single neuron.
当他移动的那一刻,你可以立即看到这个神经元正在放电,单个神经元。
I can tell you the exact channel number if you’re interested.
如果您有兴趣,我可以告诉您确切的频道号码。
It’s stuck in my brain now forever.
现在它永远留在我的脑海里了。
But that single channel firing was a beautiful indication that it was behaved really modulated, neural activity, that could then be used for downstreaming tasks, like decoding a computer cursor.
但单通道发射是一个很好的迹象,表明它的行为是真正经过调制的神经活动,然后可以用于下游任务,例如解码计算机光标。
And when you say single channel, is that associated with a single electrode?
当您说单通道时,这是否与单个电极相关?
Yeah.
是的。
5:17:18 Channel and electrode are interchangeable.
通道和电极可以互换。
And there’s a 1,024 of those?
其中有 1,024 个吗?
1,024.
1,024。
5:17:23 Yeah.
是的。
That’s incredible that, that works.
令人难以置信的是,它有效。
5:17:25 When I was learning about all this and loading it in, it was just blowing my mind that the intention, you can visualize yourself moving the finger.
当我了解所有这些并将其加载时,你可以想象自己移动手指的意图让我大吃一惊。
That can turn into a signal, and the fact that you can then skip that step and visualize the cursor moving, or have the intention of the cursor moving.
这可以变成一个信号,然后您可以跳过该步骤并想象光标移动,或者有光标移动的意图。
And that leading to a signal that can then be used to move the cursor?
这会产生一个可用于移动光标的信号吗?
There is so many exciting things there to learn about the brain, about the way the brain works, the very fact of there existing signal that can be used, is really powerful.
关于大脑,关于大脑的工作方式,有很多令人兴奋的事情可以了解,事实上存在可以使用的信号,这真的很强大。
Yep.
是的。
But it feels like that’s just the beginning of figuring out how that signal could be used really, really effectively?
但感觉这只是弄清楚如何真正有效地使用该信号的开始?
5:18:03 I should also just, there’s so many fascinating details here, but you mentioned the body mapping step.
我还应该只是,这里有很多令人着迷的细节,但你提到了身体映射步骤。
At least in the version I saw, that Noland was showing off, there’s a super nice interface, a graphical interface, but it just felt like I was in the future.
至少在我看到的版本中,诺兰炫耀的,有一个超级漂亮的界面,一个图形界面,但感觉就像我在未来。
5:18:28 I guess it visualizes you moving the hand, and there’s a very sexy polished interface that, “Hello,” I don’t know if there’s a voice component, but it just felt like when you wake up in a really nice video game, and this is the tutorial at the beginning of that video game.
我想它会想象你移动手,并且有一个非常性感的抛光界面,“你好”,我不知道是否有语音组件,但感觉就像你在一个非常好的视频游戏中醒来,这是该视频游戏开始时的教程。
This is what you’re supposed to do.
这就是你应该做的。
It’s cool.
这很酷。
No, I mean the future should feel like the future.
不,我的意思是未来应该像未来一样。
But it’s not easy to pull that off.
但要实现这一目标并不容易。
5:18:52 I mean, it needs to be simple, but not too simple.
我的意思是,它需要简单,但又不能太简单。
Yeah.
是的。
5:18:57 And I think the UX design component here is underrated for BCI development in general.
我认为这里的 UX 设计组件对于 BCI 开发来说总体上被低估了。
There’s a whole interaction effect between the ways in which you visualize an instruction to the user, and the kinds of signal you can get back.
您向用户可视化指令的方式与您可以返回的信号类型之间存在着完整的交互效应。
And that quality of your behavioral alignment to the neural signal, is a function of how good you are at expressing to the user what you want them to do.
你的行为与神经信号的一致性取决于你向用户表达你希望他们做什么的能力。
And so yeah, we spend a lot of time thinking about the UX, of how we build our applications, of how the decoder actually functions, the control surfaces it provides to the user.
所以,是的,我们花了很多时间思考用户体验、如何构建应用程序、解码器的实际功能以及它为用户提供的控制界面。
All these little details matter a lot.
所有这些小细节都很重要。
So maybe it’d be nice to get into a little bit more detail of what the signal looks like, and what the decoding looks like?
因此,也许更详细地了解信号的样子以及解码的样子会更好吗?
Yep.
是的。
So there’s a N1 implant that has, like we mentioned, 1,024 electrodes, and that’s collecting raw data, raw signal.
就像我们提到的,N1 植入物有 1,024 个电极,它正在收集原始数据、原始信号。
5:19:34 What does that signal look like?
这个信号是什么样的?
And what are the different steps along the way before it’s transmitted, and what is transmitted?
传输之前有哪些不同的步骤,传输了什么?
All that kind of stuff.
所有这些东西。
Yep.
是的。
5:19:56 This is going to be a fun one.
这将是一件有趣的事情。
Grab the [inaudible 05:19:58].
抓住 [听不清 05:19:58]。
Let’s go.
我们走吧。
So maybe before diving into what we do, it’s worth understanding what we’re trying to measure, because that dictates a lot of the requirements for the system that we build.
因此,也许在深入研究我们所做的事情之前,有必要了解我们正在尝试衡量的内容,因为这决定了我们构建的系统的许多要求。
5:19:59 And what we’re trying to measure is really individual neurons, producing action potentials.
我们想要测量的是真正产生动作电位的单个神经元。
And action potential is, you can think of it like a little electrical impulse that you can detect, if you’re close enough.
动作电位是,你可以把它想象成一个你可以检测到的小电脉冲,如果你足够接近的话。
And by being close enough, I mean within let’s say 100 microns of that cell.
我所说的足够近是指距离该细胞 100 微米之内。
And 100 microns is a very, very tiny distance.
100微米是一个非常非常小的距离。
And so the number of neurons that you’re going to pick up with any given electrode, is just a small radius around that electrode.
因此,您将使用任何给定电极拾取的神经元数量只是该电极周围的一个小半径。
5:20:33 And the other thing worth understanding about the underlying biology here, is that when neurons produce an action potential, the width of that action potential is about one millisecond.
关于这里的基础生物学,另一件值得理解的事情是,当神经元产生动作电位时,该动作电位的宽度约为一毫秒。
So from the start of the spike, to the end of the spike, that whole width of that characteristic feature, of a neuron firing, is one millisecond wide.
因此,从尖峰的开始到尖峰的结束,神经元放电的特征的整个宽度是一毫秒宽。
And if you want to detect that an individual spike is occurring or not, you need to sample that signal, or sample the local fuel potential nearby that a neuron…
如果你想检测单个尖峰是否发生,你需要对该信号进行采样,或者对神经元附近的局部燃料电位进行采样……
Much more frequently than once a millisecond.
比每毫秒一次的频率要高得多。
You need to sample many, many times per millisecond, to be able to detect that this is actually the characteristic waveform of a neuron producing an action potential.
您需要每毫秒采样很多次,才能检测到这实际上是产生动作电位的神经元的特征波形。
5:21:07 And so we sample across all 1,024 electrodes, about 20,000 times a second.
因此,我们对所有 1,024 个电极进行采样,每秒大约 20,000 次。
20,000 times a second means for any given one millisecond window, we have about 20 samples that tell us what that exact shape of that actual potential looks like.
每秒 20,000 次意味着对于任何给定的一毫秒窗口,我们有大约 20 个样本可以告诉我们实际电势的确切形状是什么样的。
And once we’ve sort of sampled at super high rate the underlying electrical field nearby these cells, we can process that signal into just where do we detect a spike, or where do we not?
一旦我们以超高速率对这些细胞附近的潜在电场进行采样,我们就可以将该信号处理为我们在哪里检测到尖峰,或者在哪里检测不到尖峰?
Sort of a binary signal, one or zero.
一种二进制信号,一或零。
Do we detect a spike in this one millisecond or not?
我们是否在这一毫秒内检测到峰值?
5:21:39 And we do that because the actual information carrying subspace of neural activity, is just when our spikes occurring.
我们这样做是因为神经活动的实际信息携带子空间正是在我们的尖峰发生时。
Essentially everything that we care about for decoding can be captured or represented in the frequency characteristics of spike trains.
本质上,我们关心的解码的所有内容都可以在尖峰序列的频率特性中捕获或表示。
Meaning, how often are spikes firing in any given window of time.
意思是,在任何给定的时间窗口内尖峰触发的频率。
And so that allows us to do sort of a crazy amount of compression, from this very rich high-density signal, to something that’s much, much more sparse and compressible, that can be sent out over a wireless radio.
因此,这使我们能够进行疯狂的压缩,从非常丰富的高密度信号,到可以通过无线电发送的更加稀疏和可压缩的信号。
Like a Bluetooth communication for example.
例如蓝牙通信。
Quick tangents here.
这里快速切线。
5:22:14 You mentioned electrode neuron, there’s a local neighborhood of neurons nearby.
你提到了电极神经元,附近有一个神经元的局部邻域。
How difficult is it to isolate from where the spike came from?
隔离尖峰的来源有多困难?
So there’s a whole field of academic neuroscience work on exactly this problem, of basically given a single electrode, or given a set of electrodes measuring a set of neurons.
因此,整个学术神经科学领域都在研究这个问题,基本上是给定一个电极,或者给定一组测量一组神经元的电极。
5:22:30 How can you sort, spike sort, which spikes are coming from what neuron?
你如何排序,尖峰排序,哪些尖峰来自哪个神经元?
And this is a problem that’s pursued in academic work, because you care about it for understanding what’s going on in the underlying neuroscience of the brain.
这是学术工作中所追求的一个问题,因为你关心它是为了了解大脑底层神经科学中正在发生的事情。
If you care about understanding how the brain’s representing information, how that’s evolving through time, then that’s a very, very important question to understand.
如果你关心了解大脑如何表示信息,以及信息如何随时间演变,那么这是一个需要理解的非常非常重要的问题。
5:23:02 For the engineering side of things, at least at the current scale, if the number of neurons per electrode is relatively small, you can get away with basically ignoring that problem completely.
对于工程方面来说,至少在目前的规模上,如果每个电极的神经元数量相对较小,那么您基本上可以完全忽略这个问题。
You can think of it like a random projection of neurons to electrodes, and there may be in some cases more than one neuron per electrode.
您可以将其视为神经元到电极的随机投影,并且在某些情况下,每个电极可能有多个神经元。
But if that number is small enough, those signals can be thought of as sort of a union of the two.
但如果这个数字足够小,这些信号可以被认为是两者的联合。
5:23:25 And for many applications, that’s a totally reasonable trade-off to make, and can simplify the problem a lot.
对于许多应用程序来说,这是一个完全合理的权衡,并且可以大大简化问题。
And as you sort of scale out channel count, the relevance of distinguishing individual neurons becomes less important.
当你扩展通道数量时,区分单个神经元的相关性就变得不那么重要了。
Because you have more overall signal, and you can start to rely on correlations or covariate structure in the data to help understand when that channel is firing…
因为您有更多的整体信号,并且您可以开始依赖数据中的相关性或协变量结构来帮助了解该通道何时触发......
What does that actually represent?
这实际上代表什么?
Because you know that when that channel’s firing in concert with these other 50 channels, that means move left.
因为您知道,当该通道与其他 50 个通道同步触发时,这意味着向左移动。
But when that same channel’s firing with concert with these other 10 channels, that means move right.
但是,当同一通道与其他 10 个通道同步发射时,就意味着向右移动。
Okay.
好的。
5:23:53 So you have to do this kind of spike detection onboard, and you have to do that super efficiently?
所以你必须在机上进行这种尖峰检测,并且必须非常高效?
So fast, and not use too much power, because you don’t want to be generating too much heat, so it’d have to be a super simple signal processing step?
这么快,而且不使用太多功率,因为你不想产生太多热量,所以它必须是一个超级简单的信号处理步骤?
Yep.
是的。
Is there some wisdom you can share about what it takes to overcome that challenge?
您是否可以分享一些关于如何克服这一挑战的智慧?
Yeah.
是的。
5:24:17 So we’ve tried many different versions of basically turning this raw signal into a feature that you might want to send off the device.
因此,我们尝试了许多不同的版本,基本上将这种原始信号转换为您可能想要从设备发送的功能。
And I’ll say that I don’t think we’re at the final step of this process, this is a long journey.
我想说的是,我认为我们还没有到达这个过程的最后一步,这是一个漫长的旅程。
We have something that works clearly today, but there can be many approaches that we find in the future that are much better than what we do right now.
今天我们有一些明显有效的方法,但我们将来可能会发现许多比我们现在所做的更好的方法。
So some versions of what we do right now, and there’s a lot of academic heritage to these ideas, so I don’t want to claim that these are original Neuralink ideas or anything like that.
所以我们现在所做的一些版本,这些想法有很多学术遗产,所以我不想声称这些是原始的 Neuralink 想法或类似的东西。
5:24:44 But one of these ideas is basically to build sort of like a convolutional filter almost, if you will.
但其中一个想法基本上是构建一个类似于卷积滤波器的东西,如果你愿意的话。
That slides across the signal and looks for a certain template to be matched.
它会在信号上滑动并寻找要匹配的特定模板。
That template consists of how deep the spike modulates, how much it recovers, and what the duration and window of time is for that, the whole process takes.
该模板包括尖峰调节的深度、恢复的程度以及整个过程所需的持续时间和时间窗口。
And if you can see in the signal that, that template is matched within certain bounds, then you can say, “Okay, that’s a spike.” One reason that approach is super convenient, is that you can actually implement that extremely efficiently in hardware.
如果您可以在信号中看到该模板在一定范围内匹配,那么您可以说,“好吧,这是一个峰值。”该方法非常方便的原因之一是您实际上可以在硬件中非常有效地实现该方法。
Which means that you can run it in low power across 1,024 channels all at once.
这意味着您可以同时在 1,024 个通道上以低功耗运行。
5:25:20 Another approach that we’ve recently started exploring, and this can be combined with the spike detection approach, is something called spike band power.
我们最近开始探索的另一种方法可以与尖峰检测方法相结合,称为尖峰带功率。
And the benefits of that approach are that you may be able to pick up some signal from neurons that are maybe too far away to be detected as a spike, because the farther away you are from an electrode, the weaker that actual spike waveform will look like on that electrode.
这种方法的好处是,您可能能够从距离太远而无法被检测为尖峰的神经元中获取一些信号,因为您距离电极越远,该电极上的实际尖峰波形就越弱。
So you might be able to pick up population level activity of things that are maybe slightly outside the normal recording radius…
因此,您也许能够捕捉到可能稍微超出正常记录半径的事物的人口水平活动……
What neuroscientists sometimes refer to as the hash of activity, the other stuff that’s going on.
神经科学家有时将其称为活动的哈希值,即正在发生的其他事情。
And you can look at across many channels how that background noise is behaving, and you might be able to get more juice out of the signal that way.
您可以通过多个通道查看背景噪声的表现,这样您就可以从信号中获得更多的信息。
5:25:59 But it comes at a cost.
但这是有代价的。
That signal is now a floating point representation, which means it’s more expensive to send out over a power.
该信号现在是浮点表示,这意味着通过功率发送的成本更高。
It means you have to find different ways to compress it, that are different than what you can apply to binary signals.
这意味着您必须找到不同的方法来压缩它,这与应用于二进制信号的方法不同。
So there’s a lot of different challenges associated with these different modalities.
因此,这些不同的模式存在很多不同的挑战。
So also in terms of communication, you’re limited by the amount of data you can send?
那么在通信方面,您也受到可以发送的数据量的限制吗?
Yeah.
是的。
And also because you’re currently using the Bluetooth protocol, you have to batch stuff together?
而且因为您当前正在使用蓝牙协议,所以您必须将东西一起批处理?
5:26:17 But you have to also do this, keeping the latency crazy low?
但您也必须这样做,保持极低的延迟?
Crazy low?
疯狂低?
Anything to say about the latency?
关于延迟有什么要说的吗?
Yeah.
是的。
5:26:32 This is a passion project of mine.
这是我的一个充满热情的项目。
So I want to build the best mouse in the world.
所以我想打造世界上最好的鼠标。
I don’t want to build the Chevrolet Spark or whatever of electric cars.
我不想生产雪佛兰 Spark 或其他电动汽车。
I want to build the Tesla Roadster version of a mouse.
我想制作 Tesla Roadster 版本的鼠标。
And I really do think it’s quite possible that within five to 10 years that most eSports competitions are dominated by people with paralysis.
我确实认为,在五到十年内,大多数电子竞技比赛很可能会由瘫痪者主导。
5:26:54 This is a very real possibility for a number of reasons.
出于多种原因,这是一种非常现实的可能性。
One is that they’ll have access to the best technology to play video games effectively.
一是他们将能够使用最好的技术来有效地玩视频游戏。
The second is they have the time to do so.
第二是他们有时间这样做。
So those two factors together are particularly potent for eSport competitors.
因此,这两个因素加在一起对于电子竞技选手来说尤其有效。
Unless, people without paralysis are also allowed to implant N1?
除非,没有瘫痪的人也可以植入N1?
Right.
正确的。
Which, it is another way to interact with a digital device, and there’s something to that, if it’s a fundamentally different experience, more efficient experience?
这是与数字设备交互的另一种方式,如果这是一种根本不同的体验、更高效的体验,那么它是有意义的吗?
5:27:13 Even if it’s not like some kind of full-on high bandwidth communication, if it’s just the ability to move the mouse 10X faster, like the bits per second?
即使它不像某种全面的高带宽通信,如果它只是能够将鼠标移动速度提高 10 倍,比如每秒位数?
If I can achieve a bits per second at 10X what I can do with a mouse, that’s a really interesting possibility of what that can do?
如果我能以 10 倍于鼠标的速度实现每秒比特数,那这真的是一个非常有趣的可能性吗?
Especially as you get really good at it.
尤其是当你真的很擅长的时候。
With training.
通过训练。
It’s definitely the case that you have a higher ceiling performance, because you don’t have to buffer your intention through your arm, through your muscle.
毫无疑问,你的表现上限更高,因为你不必通过你的手臂、通过你的肌肉来缓冲你的意图。
5:27:47 You get just by nature of having a brain implant at all, like 75 millisecond lead time on any action that you’re actually trying to take.
大脑植入是天生的,比如你真正想要采取的任何行动都有 75 毫秒的准备时间。
And there’s some nuance to this, there’s evidence that the motor cortex, you can sort of plan out sequences of actions, so you may not get that whole benefit all the time.
这有一些细微差别,有证据表明运动皮层,你可以计划出一系列的动作,所以你可能不会一直得到全部好处。
But for reaction time style games, where you just want to…
但对于反应时间风格的游戏,你只想……
Somebody’s over here, snipe them, that kind of thing?
有人在这里,狙击他们,之类的?
You actually do have just an inherent advantage, because you don’t need to go through muscle.
实际上你确实拥有先天的优势,因为你不需要通过肌肉。
5:28:18 So the question is, just how much faster can you make it?
所以问题是,你能做到多快?
And we’re already faster than what you would do if you’re going through muscle from a latency point of view, and we’re in the early stages of that.
从延迟的角度来看,我们已经比你通过肌肉进行的速度更快了,而且我们正处于早期阶段。
I think we can push it.
我想我们可以推动它。
So our end to end latency right now from brain spike to cursor movement, it’s about 22 milliseconds.
所以我们现在从大脑尖峰到光标移动的端到端延迟约为 22 毫秒。
If you think about the best mice in the world, the best gaming mice, that’s about five milliseconds ish of latency, depending on how you measure, depending how fast your screen refreshes, there’s a lot of characteristics that matter there.
如果您考虑世界上最好的鼠标,最好的游戏鼠标,那么延迟大约为五毫秒左右,这取决于您的测量方式,取决于屏幕刷新的速度,其中有很多特性很重要。
And the rough time for a neuron in the brain to actually impact your command of your hand is about 75 milliseconds.
大脑中的神经元真正影响你对手的控制的大概时间约为 75 毫秒。
5:28:50 So if you look at those numbers, you can see that we’re already competitive and slightly faster than what you’d get by actually moving your hand.
因此,如果您查看这些数字,您会发现我们已经具有竞争力,并且比您实际移动手所获得的速度稍快。
And this is something that if you ask Noland about it, when he moved the cursor for the first time…
如果你问诺兰,当他第一次移动光标时,就会发现这一点……
We asked him about this, it was something I was super curious about.
我们向他询问了这个问题,这是我非常好奇的事情。
“What does it feel like when you’re modulating a click intention, or when you’re trying to just move the cursor to the right?” He said it moves before he is actually intending it to.
“当你调整点击意图时,或者当你试图将光标向右移动时,感觉如何?”他说它在他真正打算之前就移动了。
Which is kind of a surreal thing, and something that I would love to experience myself one day, what is that like to have the thing just be so immediate, so fluid, that it feels like it’s happening before you’re actually intending it to move?
这是一种超现实的事情,我很想有一天亲自体验一下,让事情变得如此直接、如此流畅,感觉就像在你真正想要它移动之前它就发生了,那是什么样的感觉?
Yeah.
是的。
5:29:25 I suppose we’ve gotten used to that latency, that natural latency that happens.
我想我们已经习惯了这种延迟,这种自然发生的延迟。
So is currently the bottleneck, the communication?
那么目前的瓶颈是沟通吗?
So the Bluetooth communication?
那么蓝牙通讯呢?
What’s the actual bottleneck?
真正的瓶颈是什么?
I mean there’s always going to be a bottleneck, what’s the current bottleneck?
我的意思是总会有瓶颈,目前的瓶颈是什么?
Yeah.
是的。
5:29:38 A couple things.
有几件事。
So kind of hilariously, Bluetooth low- energy protocol has some restrictions on how fast you can communicate.
有趣的是,蓝牙低功耗协议对通信速度有一些限制。
So the protocol itself establishes a standard of the most frequent sort of updates you can send, are on the order of 7.5 milliseconds.
因此,协议本身建立了您可以发送的最频繁更新类型的标准,约为 7.5 毫秒。
And as we push latency down to the level of individual spikes impacting control, that level of resolution, that kind of protocol is going to become a limiting factor at some scale.
当我们将延迟降低到影响控制的单个峰值水平时,这种分辨率水平、这种协议将在一定程度上成为限制因素。
5:30:06 Another sort of important nuance to this, is that it’s not just the Neuralink itself that’s part of this equation.
另一个重要的细微差别是,这个方程的一部分不仅仅是 Neuralink 本身。
If you start pushing latency below the level of how fast you’re going to refresh, then you have another problem.
如果您开始将延迟降低到刷新速度以下,那么您就会遇到另一个问题。
You need your whole system to be able to be as reactive as the limits of what the technology can offer.
您需要整个系统能够在技术所能提供的限制范围内做出反应。
Yes.
是的。
120 hertz just doesn’t work anymore, if you’re trying to have something respond at something that’s at the level of one millisecond.
如果你想让某些东西在一毫秒级别上做出响应,120 赫兹就不再起作用了。
That’s a really cool challenge.
这是一个非常酷的挑战。
5:30:32 I also like that for a T-shirt, the best mouse in the world.
我也喜欢 T 恤,世界上最好的鼠标。
Tell me on the receiving end, so the decoding step?
告诉我在接收端,解码步骤是什么?
Now we figured out what the spikes are, we’ve got them all together, now we’re sending that over to the app.
现在我们弄清楚了尖峰是什么,我们把它们放在一起,现在我们将其发送到应用程序。
What’s the decoding step look like?
解码步骤是什么样的?
Yeah.
是的。
5:30:49 So maybe first, what is decoding?
那么首先,什么是解码?
I think there’s probably a lot of folks listening that just have no clue what it means to decode brain activity.
我想可能有很多人在听,只是不知道解码大脑活动意味着什么。
Actually, even if we zoom out beyond that, what is the app?
事实上,即使我们缩小范围,这个应用程序是什么?
5:30:56 So there’s an implant that’s wirelessly communicating with any digital device that has an app installed.
因此,有一种植入物可以与任何安装了应用程序的数字设备进行无线通信。
Yep.
是的。
So maybe can you tell me at high-level what the app is, what the software is outside of the brain?
那么也许你能从高层次上告诉我这个应用程序是什么,这个软件在大脑之外是什么?
So maybe working backwards from the goal.
所以也许从目标开始倒退。
5:31:15 The goal is to help someone with paralysis.
目标是帮助瘫痪的人。
In this case, Noland.
在这种情况下,诺兰.
Be able to navigate his computer independently.
能够独立操作他的计算机。
And we think the best way to do that, is to offer them the same tools that we have to navigate our software.
我们认为最好的方法是为他们提供与我们导航软件相同的工具。
Because we don’t want to have to rebuild an entire software ecosystem for the brain, at least not yet.
因为我们不想为大脑重建整个软件生态系统,至少现在还不想。
Maybe someday you can imagine there’s UXs that are built natively for BCI, but in terms of what’s useful for people today, I think most people would prefer to be able to just control mouse and keyboard inputs, to all the applications that they want to use for their daily jobs, for communicating with their friends, et cetera.
也许有一天你可以想象有一些为 BCI 原生构建的用户体验,但就对当今人们有用的方面而言,我认为大多数人更愿意能够只控制鼠标和键盘输入,而不是他们想要用于日常工作、与朋友交流等的所有应用程序。
5:31:47 And so the job of the application is really to translate this wireless stream of brain data, coming off the implant, into control of the computer.
因此,应用程序的工作实际上是将来自植入物的无线大脑数据流转换为计算机的控制。
And we do that by essentially building a mapping from brain activity to sort of the HID inputs, to the actual hardware.
我们通过构建从大脑活动到 HID 输入到实际硬件的映射来实现这一点。
So HID is just the protocol for communicating like input device events, so for example, move mouse to this position or press this key down.
所以HID只是像输入设备事件一样进行通信的协议,所以例如将鼠标移动到这个位置或者按下这个键。
And so that mapping is fundamentally what the app is responsible for.
因此,映射从根本上来说是应用程序负责的事情。
But there’s a lot of nuance of how that mapping works, and we spent a lot of time to try to get it right, and we’re still in the early stages of a long journey to figure out how to do that optimally.
但映射的工作方式存在很多细微差别,我们花了很多时间来尝试使其正确,而且我们仍处于弄清楚如何最佳地做到这一点的漫长旅程的早期阶段。
5:32:21 So one part of that process is decoding.
因此,该过程的一部分就是解码。
So decoding is this process of taking the statistical patterns of brain data, that’s being channeled across this Bluetooth connection to the application.
因此,解码是获取大脑数据统计模式的过程,这些数据通过蓝牙连接传输到应用程序。
And turning it into, for example, a mouse movement.
并将其转化为例如鼠标移动。
And that decoding step, you can think of it in a couple of different parts.
对于解码步骤,您可以将其分为几个不同的部分。
So similar to any machine learning problem, there’s a training step, and there’s an [inaudible 05:32:39] step.
与任何机器学习问题类似,有一个训练步骤,还有一个 [听不清 05:32:39] 步骤。
The training step in our case is a very intricate behavioral process where the user has to imagine doing different actions.
在我们的例子中,训练步骤是一个非常复杂的行为过程,用户必须想象做不同的动作。
So for example, they’ll be presented a screen with a cursor on it, and they’ll be asked to push that cursor to the right.
例如,他们将看到一个带有光标的屏幕,并且会要求他们将该光标推到右侧。
Then imagine pushing that cursor to the left, push it up, push it down.
然后想象将光标向左推、向上推、向下推。
And we can basically build up a pattern or using any sort of modern ML method of mapping of given this brain data, and then imagine behavior, map one to the other.
我们基本上可以建立一种模式,或者使用任何一种现代机器学习方法来映射给定的大脑数据,然后想象行为,将一个映射到另一个。
5:33:07 And then at test time you take that same pattern matching system.
然后在测试时,您采用相同的模式匹配系统。
In our case it’s a deep neural network, and you run it and you take the live stream of brain data coming off their implant, you decode it by pattern matching to what you saw at calibration time, and you use that for a control of the computer.
在我们的例子中,它是一个深度神经网络,你运行它,获取来自植入物的实时大脑数据流,通过与校准时看到的模式匹配来解码它,然后用它来控制计算机。
Now a couple sort of rabbit holes that I think are quite interesting.
现在有一些我认为非常有趣的兔子洞。
One of them has to do with how you build that best template matching system.
其中之一与如何构建最佳模板匹配系统有关。
Because there’s a variety of behavioral challenges and also debugging challenges when you’re working with someone who’s paralyzed.
因为当你与瘫痪的人一起工作时,会遇到各种各样的行为挑战和调试挑战。
5:33:35 Because again, fundamentally you don’t observe what they’re trying to do, you can’t see them attempt to move their hand.
因为从根本上来说,你不会观察到他们试图做什么,你也看不到他们试图移动他们的手。
And so you have to figure out a way to instruct the user to do something, and validate that they’re doing it correctly, such that then you can downstream, build with confidence, the mapping between the neural spikes and the intended action.
因此,你必须找到一种方法来指导用户做某事,并验证他们是否正确地做事,这样你就可以在下游自信地构建神经尖峰和预期动作之间的映射。
5:33:53 And by doing the action correctly, what I really mean is, at this level of resolution of what neurons are doing.
通过正确地执行动作,我真正的意思是,在神经元正在做的事情的分辨率水平上。
So if, in ideal world, you could get a signal of behavioral intent that is ground truth accurate at the scale of one millisecond resolution, then with high confidence, I could build a mapping from my neural spikes, to that behavioral intention.
因此,如果在理想的世界中,您可以获得以一毫秒分辨率为基准的准确的行为意图信号,那么我就可以高度自信地构建从我的神经尖峰到该行为意图的映射。
But the challenge is again, that you don’t observe what they’re actually doing.
但挑战又是,你没有观察到他们实际上在做什么。
And so there’s a lot of nuance to how you build user experiences, that give you more than just a course on average correct representation of what the user’s intending to do.
因此,如何构建用户体验有很多细微差别,这不仅仅是一门平均正确表达用户意图的课程。
5:34:24 If you want to build the world’s best mouse, you really want it to be as responsive as possible.
如果您想打造世界上最好的鼠标,您确实希望它尽可能具有响应能力。
You want it to be able to do exactly what the user’s intending, at every step along the way, not just on average be correct, when you’re trying to move it from left to right.
当您尝试将其从左向右移动时,您希望它能够在每一步中准确地执行用户的意图,而不仅仅是平均而言正确。
And building a behavioral calibration game, or our software experience, that gives you that level of resolution, is what we spend a lot of time working on.
我们花费大量时间致力于构建行为校准游戏或我们的软件体验,为您提供一定程度的分辨率。
So the calibration process, the interface, has to encourage precision.
因此,校准过程、界面必须鼓励精度。
5:34:44 Meaning whatever it does, it should be super intuitive that the next thing the human is going to likely do, is exactly that intention that you need, and only that intention?
这意味着无论它做什么,人类接下来可能要做的事情都应该是超级直观的,这正是你需要的意图,而且只是那个意图?
Yeah.
是的。
And you don’t have any feedback except that may be speaking to you afterwards, what they actually did, you can’t…
你没有任何反馈,除了可能会在事后对你说话,他们实际上做了什么,你不能……
5:35:03 Oh, yeah.
哦,是的。
Right.
正确的。
So that’s fundamentally, that is a really exciting UX challenge.
所以从根本上来说,这是一个非常令人兴奋的用户体验挑战。
5:35:11 Because that’s all on the UX, it’s not just about being friendly or nice or usable.
因为这一切都与用户体验有关,而不仅仅是友好、友善或可用。
Yep.
是的。
It’s like-
就像-
User experience is how it works.
用户体验就是它的运作方式。
…
……
5:35:24 it’s how it works, for the calibration.
这就是它的工作原理,用于校准。
And calibration, at least at this stage of Neuralink is fundamental to the operation of the thing?
校准,至少在 Neuralink 的现阶段是该设备运行的基础?
And not just calibration, but continued calibration essentially?
不仅是校准,而且本质上是持续校准?
Yeah.
是的。
Wow, yeah.
哇,是的。
You said something that I think is worth exploring there a little bit.
你说了一些我认为值得探讨的事情。
5:35:40 You said it’s primarily a UX challenge, and I think a large component of it is, but there is also a very interesting machine learning challenge here.
你说这主要是一个用户体验挑战,我认为其中很大一部分是挑战,但这里还有一个非常有趣的机器学习挑战。
Which is given some dataset, including some on average correct behavior, of asking the user to move up, or move down, move right, move left, and given a dataset of neural spikes.
给出一些数据集,包括一些平均正确的行为,要求用户向上移动、向下移动、向右移动、向左移动,并给出神经尖峰的数据集。
Is there a way to infer, in some kind of semi-supervised, or entirely unsupervised way, what that high resolution version of their intention is?
有没有办法以某种半监督或完全无监督的方式推断出他们意图的高分辨率版本是什么?
5:36:10 And if you think about it, there probably is, because there are enough data points in the dataset, enough constraints on your model.
如果您考虑一下,由于数据集中有足够的数据点,因此您的模型可能存在足够的约束。
That there should be a way with the right sort of formulation, to let the model figure out itself, for example…
应该有一种方法可以采用正确的表述方式,让模型自行解决,例如……
At this millisecond, this is exactly how hard they’re pushing upwards, and at this millisecond, this is how hard they’re trying to push upwards.
在这一毫秒,这就是他们向上推动的力度,在这一毫秒,这就是他们试图向上推动的力度。
It’s really important to have very clean labels, yes?
拥有非常干净的标签真的很重要,是吗?
5:36:27 So the problem becomes much harder from the machine learning perspective if the labels are noisy?
那么,如果标签有噪声,从机器学习的角度来看,问题就会变得更加困难?
That’s correct.
这是正确的。
And then to get the clean labels, that’s a UX challenge?
然后要获得清洁标签,这是用户体验挑战吗?
Correct.
正确的。
5:36:40 Although clean labels, I think maybe it’s worth exploring what that exactly means.
虽然清洁标签,但我认为也许值得探索它的确切含义。
I think any given labeling strategy will have some number of assumption to make, about what the user is attempting to do.
我认为任何给定的标签策略都会对用户试图做什么做出一些假设。
Those assumptions can be formulated in a loss function, or they can be formulated in terms of heuristics that you might use, to just try to estimate or guesstimate what the user’s trying to do.
这些假设可以用损失函数来表述,也可以根据您可能使用的启发式来表述,以尝试估计或猜测用户想要做什么。
And what really matters is, how accurate are those assumptions?
真正重要的是,这些假设有多准确?
For example, you might say, “Hey, user, push upwards and follow the speed of this cursor.” And your heuristic might be that they’re trying to do exactly what that cursor is trying to do.
例如,您可能会说,“嘿,用户,向上推并跟随此光标的速度。”你的启发可能是他们正在尝试做光标想要做的事情。
5:37:10 Another competing heuristic might be, they’re actually trying to go slightly faster at the beginning of the movement and slightly slower at the end.
另一个相互竞争的启发可能是,他们实际上试图在运动开始时稍微快一点,在结束时稍微慢一点。
And those competing heuristics may or may not be accurate reflections of what the user is trying to do.
这些相互竞争的启发法可能会也可能不会准确反映用户正在尝试做的事情。
Another version of the task might be, “Hey, user, imagine moving this cursor a fixed offset.” So rather than follow the cursor, just try to move it exactly 200 pixels to the right.
该任务的另一个版本可能是,“嘿,用户,想象一下将此光标移动一个固定的偏移量。”因此,不要跟随光标,而是尝试将其向右移动 200 像素。
So here’s the cursor, here’s the target, okay, cursor disappears, try to move that now invisible cursor, 200 pixels to the right.
这是光标,这是目标,好吧,光标消失了,尝试将现在不可见的光标向右移动 200 像素。
And the assumption in that case would be that the user can’t actually modulate correctly that position offset.
在这种情况下,假设用户实际上无法正确调节该位置偏移。
5:37:41 But that position offset assumption might be a weaker assumption, and therefore potentially, you can make it more accurate, than these heuristics that are trying to guesstimate at each millisecond what the user’s trying to do.
但位置偏移假设可能是一个较弱的假设,因此,与这些尝试每毫秒猜测用户试图做什么的启发式方法相比,您可能可以使其更准确。
So you can imagine different tasks that make different assumptions about the nature of the user intention.
因此,您可以想象不同的任务对用户意图的性质做出不同的假设。
And those assumptions being correct is what I would think of as a clean label.
我认为这些假设是正确的,这就是干净的标签。
For that step, what are we supposed to be visualizing?
对于这一步,我们应该想象什么?
5:37:59 There’s a cursor, and you want to move that cursor to the right, or the left, or up and down, or maybe move them by a certain offset.
有一个光标,您想要将该光标向右、向左、向上或向下移动,或者将它们移动一定的偏移量。
So that’s one way.
这是一种方法。
Is that the best way to do calibration?
这是进行校准的最佳方法吗?
5:38:13 So for example, an alternative crazy way that probably is playing a role here, is a game like WEG Grid.
例如,另一种疯狂的方式可能在这里发挥作用,那就是像 WEG Grid 这样的游戏。
Where you’re just getting a very large amount of data, the person playing a game.
当你刚刚获得大量数据时,就是玩游戏的人。
Where if they’re in a state of flow, maybe you can get clean signal as a side effect?
如果它们处于流动状态,也许你可以获得干净的信号作为副作用?
Yep.
是的。
Or is that not an effective way for initial calibration?
或者这不是初始校准的有效方法?
Yeah.
是的。
5:38:38 Great question.
很好的问题。
There’s a lot to unpack there.
那里有很多东西需要解压。
So the first thing I would draw a distinction between is, open loop versus closed loop.
因此,我首先要区分的是开环与闭环。
So open loop, what I mean by that is, the user is sort of going from zero to one.
所以开环,我的意思是,用户有点从零到一。
They have no model at all, and they’re trying to get to the place where they have some level of control, at all.
他们根本没有模型,他们正试图达到他们拥有一定程度控制权的程度。
In that setup, you really need to have some task that gives the user a hint of what you want them to do, such that you can build its mapping again, from brain data to output.
在该设置中,您确实需要执行一些任务,向用户提示您希望他们做什么,以便您可以再次构建从大脑数据到输出的映射。
Then once they have a model, you could imagine them using that model and actually adapting to it, and figuring out the right way to use it themself.
一旦他们有了一个模型,你就可以想象他们使用该模型并实际适应它,并自己找出使用它的正确方法。
And then retraining on that data to give you sort of a boost in performance.
然后对这些数据进行重新训练,以提高性能。
5:39:14 There’s a lot of challenges associated with both of these techniques, and we can rabbit hole into both of them if you’re interested.
这两种技术都存在很多挑战,如果您有兴趣,我们可以深入研究这两种技术。
But the sort of challenge with the open loop task is that the user themself doesn’t get proprioceptive feedback about what they’re doing.
但开环任务的挑战在于,用户自己无法获得关于他们正在做的事情的本体反馈。
They don’t necessarily perceive themself or feel the mouse under their hand, when they’re trying to do an open loop calibration.
当他们尝试进行开环校准时,他们不一定会感知自己或感觉到鼠标在他们的手下。
They’re being asked to perform something…
他们被要求执行某事......
Imagine if you sort of had your whole right arm numbed, and you stuck it in a box and you couldn’t see it, so you had no visual feedback and you had no proprioceptive feedback, about what the position or activity of your arm was.
想象一下,如果你的整个右臂都麻木了,你把它放在一个盒子里,你看不到它,所以你没有视觉反馈,也没有本体感觉反馈,关于你的手臂的位置或活动是什么。
5:39:47 And now you’re asked, “Okay, given this thing on the screen, that’s moving from left to right, match that speed?” And you basically can try your best to invoke whatever that imagined action is in your brain, that’s moving the cursor from left to right.
现在你被问到,“好吧,考虑到屏幕上的这个东西,它从左到右移动,匹配那个速度吗?”你基本上可以尽力调用你大脑中想象的任何动作,即将光标从左向右移动。
But in any situation, you’re going to be inaccurate and maybe inconsistent in how you do that task.
但在任何情况下,你执行任务的方式都会不准确,甚至可能不一致。
And so that’s sort of the fundamental challenge of open loop.
这就是开环的基本挑战。
The challenge with closed loop is that once the user’s given a model, and they’re able to start moving the mouse on their own, they’re going to very naturally adapt to that model.
闭环的挑战在于,一旦用户给出了一个模型,并且他们能够开始自己移动鼠标,他们就会非常自然地适应该模型。
And that coadaptation between the model learning what they’re doing, and the user learning how to use the model, may not find you the best sort of global minima.
模型学习他们正在做什么和用户学习如何使用模型之间的相互适应可能无法找到最好的全局最小值。
5:40:25 And maybe that your first model was noisy in some ways, or maybe just had some quirk.
也许你的第一个模型在某些方面很吵,或者可能只是有一些怪癖。
There’s some part of the data distribution, it didn’t cover super well, and the user now figures out, because they’re a brilliant user like Noland, they figure out the right sequence of imagined motions, or the right angle they have to hold their hand at to get it to work.
数据分布的某些部分,它没有很好地覆盖,用户现在弄清楚了,因为他们是像诺兰这样的出色用户,他们弄清楚了想象的动作的正确顺序,或者他们必须握住手才能使其工作的正确角度。
And they’ll get it to work great, but then the next day they come back to their device, and maybe they don’t remember exactly all the tricks that they used the previous day.
他们会让它很好地工作,但第二天他们回到他们的设备,也许他们不记得前一天使用的所有技巧。
And so there’s a complicated sort of feedback cycle here that can emerge, and can make it a very, very difficulty debugging process.
因此,这里可能会出现一种复杂的反馈循环,并且可能使其成为一个非常非常困难的调试过程。
Okay.
好的。
5:40:56 There’s a lot of really fascinating things there.
那里有很多非常有趣的东西。
Actually, just to stay on the closed loop…
其实,只是为了保持闭环……
I’ve seen situations, this actually happened watching psychology grad students.
我见过这样的情况,这实际上是在心理学研究生身上发生的。
They used a piece of software and they don’t know how to program themselves.
他们使用了一个软件,但他们不知道如何自己编程。
They used a piece of software that somebody else wrote, and it has a bunch of bugs, and they’ve been using it for years.
他们使用了别人编写的一款软件,它有很多错误,而且他们已经使用它很多年了。
They figure out ways to walk around, “Oh, that just happens.” Nobody considers, “Maybe we should fix this.” They just adapt.
他们想出了四处走动的方法,“哦,那只是发生了。”没有人会考虑:“也许我们应该解决这个问题。”他们只是适应。
And that’s a really interesting notion, that we’re really good at it adapting, but that might not be the optimal?
这是一个非常有趣的概念,我们真的很擅长适应,但这可能不是最佳的?
Yeah.
是的。
Okay.
好的。
5:41:39 So how do you solve that problem?
那么你如何解决这个问题呢?
Do you have to restart from scratch every once in a while, kind of thing?
您是否必须每隔一段时间从头开始,之类的事情?
Yeah.
是的。
5:41:44 It’s a good question.
这是一个好问题。
First and foremost, I would say this is not a solve problem.
首先,我想说这不是一个可以解决的问题。
And for anyone who’s listening in academia who works on BCIs, I would also say this is not a problem that’s solved by simply scaling channel count.
对于任何在学术界从事 BCI 工作的人来说,我也想说这不是一个通过简单地扩展通道数量就能解决的问题。
So maybe that can help, and you can get sort of richer covariant structures that you can use to exploit, when trying to come up with good labeling strategies.
因此,也许这会有所帮助,并且在尝试提出良好的标签策略时,您可以获得更丰富的协变结构,可以利用这些结构。
But if you’re interested in problems that aren’t going to be solved inherently by scaling channel count, this is one of them.
但如果您对无法通过扩展通道数来本质上解决的问题感兴趣,这就是其中之一。
5:42:08 Yeah.
是的。
So how do you solve it?
那么如何解决呢?
It’s not a solve problem.
这不是一个可以解决的问题。
That’s the first thing I want to make sure it gets across.
这是我想要确保它被理解的第一件事。
The second thing is, any solution that involves closed loop is going to become a very difficult debugging problem.
第二件事是,任何涉及闭环的解决方案都将成为一个非常困难的调试问题。
And one of my general heuristics for choosing what prompts to tackle is, that you want to choose the one that’s going to be the easiest to debug.
我在选择要处理的提示时的一般启发之一是,您要选择最容易调试的提示。
Because if you can do that, even if the ceiling is lower, you’re going to be able to move faster, because you have a tighter iteration loop debugging the problem.
因为如果你能做到这一点,即使上限较低,你也将能够更快地前进,因为你有一个更紧密的迭代循环来调试问题。
5:42:34 In the open loop setting, there’s not a feedback cycle to debug with the user in the loop.
在开环设置中,没有反馈周期可供用户在环路中进行调试。
And so there’s some reason to think that, that should be an easier debugging problem.
因此,有理由认为,这应该是一个更容易调试的问题。
The other thing that’s worth understanding is that even in the closed loop setting, there’s no special software magic of how to infer what the user is truly attempting to do.
另一件值得理解的事情是,即使在闭环设置中,也没有特殊的软件魔法来推断用户真正想要做什么。
In the closed loop setting, although they’re moving the cursor on the screen, they may be attempting something different than what your model is outputting.
在闭环设置中,尽管他们在屏幕上移动光标,但他们可能会尝试与模型输出不同的内容。
So what the model is outputting is not a signal that you can use to retrain if you want to be able to improve the model further.
因此,如果您希望进一步改进模型,模型输出的信号并不是可以用来重新训练的信号。
You still have this very complicated guestimation, or unsupervised problem of figuring out what is the true user intention underlying that signal?
您仍然面临着非常复杂的猜测,或者无人监督的问题,无法弄清楚该信号背后的真实用户意图是什么?
5:43:09 And so the open loop problem has the nice property of being easy to debug, and the second nice property of, it has all the same information and content as the closed loop scenario.
因此,开环问题具有易于调试的良好特性,第二个良好的特性是,它具有与闭环场景相同的信息和内容。
Another thing I want to mention and call out, is that this problem doesn’t need to be solved in order to give useful control to people.
我想提及和强调的另一件事是,不需要解决这个问题即可为人们提供有用的控制。
Even today with the solutions we have now, and that academia has built up over decades, the level of control that can be given to a user today, is quite useful.
即使在今天,凭借我们现有的解决方案以及学术界几十年来建立的解决方案,今天可以给予用户的控制级别仍然非常有用。
It doesn’t need to be solved to get to that level of control.
不需要解决它就能达到这种控制水平。
5:43:38 But again, I want to build the world’s best mouse.
但我再次强调,我想打造世界上最好的鼠标。
I want to make it so good that it’s not even a question that you want it.
我想让它变得如此好,以至于你想要它都不是问题。
And to build the world’s best mouse, the superhuman version, you really need to nail that problem.
要打造世界上最好的鼠标(超人版本),您确实需要解决这个问题。
And a couple maybe details of previous studies that we’ve done internally, that I think are very interesting to understand, when thinking about how to solve this problem.
我认为在考虑如何解决这个问题时,我们内部进行的先前研究的一些细节可能非常有趣。
The first is that even when you have ground-truth data of what the user’s trying to do, and you can get this with an able-bodied monkey, a monkey that has a Neuralink device implanted, and moving a mouse to control a computer.
首先,即使你有用户想要做什么的真实数据,你也可以通过一只身体健全的猴子(一只植入了 Neuralink 设备的猴子)并移动鼠标来控制计算机来获得这些数据。
Even with that ground-truth dataset, it turns out that the optimal thing to predict to produce high performance BCI, is not just the direct control of the mouse.
即使有了真实的数据集,事实证明,预测产生高性能 BCI 的最佳方法不仅仅是直接控制鼠标。
5:44:18 You can imagine building a dataset of what’s going on in the brain, and what is the mouse exactly doing on the table?
你可以想象建立一个关于大脑中正在发生的事情的数据集,以及老鼠在桌子上到底在做什么?
And it turns out that if you build the mapping from neurospikes to predict exactly what the mouse is doing, that model will perform worse, than a model that is trained to predict higher level assumptions about what the user might be trying to do.
事实证明,如果你从神经尖峰构建映射来准确预测鼠标正在做什么,那么该模型的表现会比经过训练以预测有关用户可能尝试做什么的更高级别假设的模型表现更差。
For example, assuming that the monkey is trying to go in a straight line to the target, it turns out that making those assumptions is actually more effective in producing a model, than actually predicting the underlying hand movement.
例如,假设猴子试图沿直线到达目标,事实证明,做出这些假设实际上在生成模型方面比实际预测潜在的手部运动更有效。
So the intention, not the physical movement, or whatever?
那么是意图,而不是身体动作,还是其他什么?
Yeah.
是的。
There’s obviously a really strong correlation between the two, but the intention is a more powerful thing to be chasing?
显然,两者之间确实存在很强的相关性,但意图是一个更强大的东西值得追逐?
Right.
正确的。
Well, that’s also super interesting.
嗯,这也非常有趣。
5:44:55 I mean, the intention itself is fascinating because yes, with the BCI here in this case with the digital telepathy, you’re acting on the intention, not the action.
我的意思是,意图本身很有趣,因为是的,在这种情况下,通过 BCI 和数字心灵感应,你是根据意图行事,而不是行动。
Which is why there’s an experience of feeling like it’s happening before you meant for it to happen?
这就是为什么会有一种感觉它在你想要它发生之前就发生了的经历?
That is so cool.
那太酷了。
And that is why you could achieve superhuman performance problem, in terms of the control of the mouse?
这就是为什么你可以在鼠标的控制方面实现超人的性能问题?
So for open loop, just to clarify, so whenever the person is tasked to move the mouse to the right, you said there’s not feedback, so they don’t get to get that satisfaction of actually getting it to move?
因此,对于开环,只是为了澄清一下,所以每当人们被要求将鼠标移动到右侧时,你说没有反馈,所以他们无法获得实际移动鼠标的满足感?
Right?
正确的?
So you could imagine giving the user feedback on a screen, but it’s difficult, because at this point you don’t know what they’re attempting to do.
因此,您可以想象在屏幕上向用户提供反馈,但这很困难,因为此时您不知道他们正在尝试做什么。
5:45:38 So what can you show them that would basically give them a signal of, “I’m doing this correctly or not correctly?” So let’s take a very specific example.
那么你可以向他们展示什么,基本上可以给他们一个信号:“我做得正确或不正确?”让我们举一个非常具体的例子。
Maybe your calibration task looks like you’re trying to move the cursor, a certain position offset.
也许你的校准任务看起来像是你试图移动光标,某个位置偏移。
So your instructions to the user are, “Hey, the cursor’s here.
所以你给用户的指令是:“嘿,光标在这里。
Now when the cursor disappears, imagine you’re moving it 200 pixels from where it was, to the right to be over this target.”
现在,当光标消失时,想象一下您将其从原来的位置向右移动 200 像素,到达该目标上方。”
5:46:05 In that kind of scenario, you could imagine coming up with some sort of consistency metric that you could display to the user of, “Okay, I know what the spike trend looks like on average when you do this action to the right.
在这种情况下,您可以想象提出某种可以向用户显示的一致性指标,“好吧,我知道当您向右执行此操作时,平均峰值趋势是什么样的。
Maybe I can produce some sort of probabilistic estimate of how likely is that to be the action you took, given the latest trial or trajectory that you imagined?” And that could give the user some sort of feedback of how consistent are they, across different trials.
也许我可以根据你想象的最新试验或轨迹,对你采取的行动的可能性有多大进行某种概率估计?”这可以为用户提供某种反馈,说明他们在不同试验中的一致性。
5:46:27 You could also imagine that if the user is prompted with that kind of consistency metric, that maybe they just become more behaviorally engaged to begin with, because the task is kind of boring when you don’t have any feedback at all.
您还可以想象,如果向用户提示这种一致性指标,也许他们一开始就会在行为上变得更加投入,因为当您根本没有任何反馈时,任务会有点无聊。
And so there may be benefits to the user experience of showing something on the screen, even if it’s not accurate.
因此,在屏幕上显示某些内容可能会给用户体验带来好处,即使它不准确。
Just because it keeps the user motivated to try to increase that number, or push it upwards.
只是因为它让用户有动力尝试增加该数字或向上推它。
So there’s this psychology element here?
那么这里有心理学因素吗?
Yeah.
是的。
5:46:50 Absolutely.
绝对地。
And again, all of that is UX challenge?
再说一次,所有这些都是用户体验挑战?
5:46:52 How much signal drift is there hour-to-hour, day-to-day, week-to-week, month-to-month?
每小时、每天、每周、每月的信号漂移有多大?
How often do you have to recalibrate because of the signal drift?
由于信号漂移,您需要多久重新校准一次?
Yeah.
是的。
5:47:06 So this is a problem we’ve worked on both with NHP, non-human primates, before our clinical trial, and then also with Noland during the clinical trial.
因此,我们在临床试验之前和诺兰一起研究了这个问题。
Maybe the first thing that’s worth stating is what the goal is here.
也许首先值得说明的是这里的目标是什么。
So the goal is really to enable the user to have a plug and play experience…
所以我们的目标实际上是让用户拥有即插即用的体验......
Well, I guess they don’t have to plug anything in, but a play experience where they can use the device whenever they wanted, however they want to.
嗯,我想他们不需要插入任何东西,而是可以随时随地使用该设备的游戏体验。
And that’s really what we’re aiming for.
这正是我们的目标。
And so there can be a set of solutions that get to that state without considering this non-stationary problem.
因此,可以有一组解决方案可以在不考虑这个非平稳问题的情况下达到该状态。
5:47:38 So maybe the first solution here that’s important, is that they can recalibrate whenever they want.
因此,也许这里第一个重要的解决方案是他们可以随时重新校准。
This is something that Noland has the ability to do today, so he can recalibrate the system at 2:00 AM, in the middle of the night without his caretaker, or parents or friends around, to help push a button for him.
这是诺兰今天有能力做到的事情,因此他可以在凌晨 2:00 重新校准系统,在半夜,没有他的看护人、父母或朋友在身边帮助他按下按钮。
The other important part of the solution is that when you have a good model calibrated, that you can continue using that without needing to recalibrate it.
该解决方案的另一个重要部分是,当您校准了良好的模型后,您可以继续使用它,而无需重新校准它。
So how often he has to do this recalibration to-date, depends really on his appetite for performance.
因此,迄今为止他需要多久进行一次重新校准,实际上取决于他对表现的兴趣。
5:48:06 We observe sort of a degradation through time, of how well any individual model works, but this can be mitigated behaviorally by the user adapting their control strategy.
我们观察到,随着时间的推移,任何单个模型的工作效果都会有所下降,但这可以通过用户调整其控制策略来缓解。
It can also be mitigated through a combination of software features that we provide to the user.
它还可以通过我们向用户提供的软件功能组合来缓解。
For example, we let the user adjust exactly how fast the cursor is moving.
例如,我们让用户精确调整光标移动的速度。
We call that the gain, for example, the gain of how fast the cursor reacts to any given input intention.
我们称之为增益,例如,光标对任何给定输入意图的反应速度的增益。
5:48:27 They can also adjust the smoothing, how smooth the output of that cursor intention actually is.
他们还可以调整平滑度,即光标意图的输出实际的平滑程度。
That can also adjust the friction, which is how easy is it to stop and hold still?
那还可以调节摩擦力,这样停下来保持不动有多容易?
And all these software tools allow the user a great deal of flexibility and troubleshooting mechanisms to be able to solve this problem for themselves.
所有这些软件工具都为用户提供了很大的灵活性和故障排除机制,使其能够自行解决此问题。
By the way, all of this is done by looking to the right side of the screen, selecting the mixer.
顺便说一句,所有这一切都是通过查看屏幕右侧并选择混音器来完成的。
5:48:42 And the mixer you have, it’s-
你拥有的搅拌机是-
Like DJ mode.
就像 DJ 模式一样。
5:48:48 DJ mode for your BCI.
BCI 的 DJ 模式。
I mean, it’s a really well done interface.
我的意思是,这是一个做得非常好的界面。
5:48:52 It’s really, really well done.
确实做得非常非常好。
And so there’s that bias that there’s a cursor drift that Noland talked about in a stream.
因此,诺兰在直播中谈到了光标漂移,这存在偏见。
Although he said that you guys were just playing around with it with him, and then constantly improving.
虽然他说你们只是跟他玩玩,然后不断进步。
So that could have been just a snapshot of that particular moment, a particular day, where he said that there was this cursor drift and this bias that could be removed by him.
因此,这可能只是那个特定时刻、特定日子的快照,他说存在光标漂移和他可以消除的偏见。
I guess, looking to the right side of the screen, or left side of the screen, to adjust the bias?
我想,看屏幕的右侧或屏幕的左侧来调整偏差?
Yeah, yeah.
是啊是啊。
That’s one interface action, I guess, to adjust the bias?
我猜这是调整偏差的一个界面操作?
Yeah.
是的。
5:49:28 So this is actually an idea that comes out of academia.
所以这实际上是学术界的一个想法。
There is some prior work with BrainGate clinical trial participants where they pioneered this idea of bias correction.
之前有一些与 BrainGate 临床试验参与者合作的工作,他们率先提出了这种偏差校正的想法。
The way we’ve done it, I think is, it’s very prioritized, very beautiful user experience.
我认为我们的做法是,这是非常优先的、非常漂亮的用户体验。
Where the user can essentially flash the cursor over to the side of the screen, and it opens up a window, where they can actually adjust or tune exactly the bias of the cursor.
用户基本上可以将光标闪到屏幕的一侧,然后打开一个窗口,他们可以在其中实际调整或精确调整光标的偏差。
So bias, maybe for people who aren’t familiar, is just sort of what is the default motion of the cursor, if you’re imagining nothing?
那么,对于不熟悉的人来说,偏差只是光标的默认运动(如果您什么也没想象的话)?
And it turns out that, that’s one of the first sort-
事实证明,这是第一种——
5:50:00 …
……
and it turns out that that’s one of the first qualia of the cursor control experience that’s impacted by neuron [inaudible 05:50:07]
事实证明,这是受神经元影响的光标控制体验的第一个感受性 [听不清 05:50:07]
Qualia of the cursor experience.
光标体验的品质。
I mean, I don’t know how else to describe it.
我的意思是,我不知道还能如何描述它。
5:50:08 I’m not the guy moving thing.
我不是那个搬东西的人。
It’s very poetic.
非常有诗意。
5:50:14 I love it.
我喜欢它。
The qualia of the cursor experience.
光标体验的品质。
Yeah, I mean it sounds poetic, but it is deeply true.
是的,我的意思是这听起来很诗意,但它是非常真实的。
There is an experience.
有一个经验。
When it works well, it is a joyful…
当它运作良好时,这是一种快乐……
A really pleasant experience.
一次非常愉快的经历。
And when it doesn’t work well, it’s a very frustrating experience.
当它不能很好地发挥作用时,这将是一次非常令人沮丧的经历。
That’s actually the art of UX, you have the possibility to frustrate people, or the possibility to give them joy.
这实际上是用户体验的艺术,你有可能让人们沮丧,也有可能给他们带来快乐。
And at the end of the day, it really is truly the case that UX is how the thing works.
归根结底,用户体验确实是事物运作的方式。
5:50:40 And so it’s not just what’s showing on the screen, it’s also, what control surfaces does a decoder provide the user?
因此,这不仅仅是屏幕上显示的内容,还包括解码器为用户提供哪些控制界面?
We want them to feel like they’re in the F1 car, not like some minivan.
我们希望他们感觉自己就像在 F1 赛车中,而不是像一些小型货车。
And that really truly is how we think about it.
这确实是我们的想法。
Noland himself is an F1 fan.
诺兰本人也是一位F1车迷。
We refer to ourself as a pit crew, he really is truly the F1 driver.
我们称自己为维修站工作人员,他确实是真正的 F1 车手。
And there’s different control surfaces that different kinds of cars and airplanes provide the user, and we take a lot of inspiration from that when designing how the cursor should behave.
不同类型的汽车和飞机为用户提供了不同的控制界面,我们在设计光标的行为方式时从中获得了很多灵感。
5:51:11 And maybe one nuance of this is, even details like when you move a mouse on a MacBook trackpad, the sort of response curve of how that input that you give the trackpad translates to cursor movement is different than how it works with a mouse.
也许其中的一个细微差别是,即使是像当您在 MacBook 触控板上移动鼠标这样的细节,您向触控板提供的输入如何转换为光标移动的响应曲线也不同于使用鼠标的工作方式。
When you move on the trackpad, there’s a different response function, a different curve to how much a movement translates to input to the computer than when you do it physically with a mouse.
当您在触控板上移动时,与使用鼠标进行物理操作时相比,会有不同的响应函数,以及将移动转换为计算机输入的程度不同的曲线。
And that’s because somebody sat down a long time ago, when they’re designing the initial input systems to any computer, and they thought through exactly how it feels to use these different systems.
那是因为很久以前有人坐下来,当他们为任何计算机设计初始输入系统时,他们仔细思考了使用这些不同系统的感觉。
And now we’re designing the next generation of this, input system to a computer, which is entirely done via the brain, and there’s no proprioceptive feedback, again, you don’t feel the mouse in your hand, you don’t feel the keys under your fingertips, and you want a control surface that still makes it easy and intuitive for the user to understand the state of the system, and how to achieve what they want to achieve.
现在我们正在设计下一代的计算机输入系统,这完全是通过大脑完成的,并且没有本体感觉反馈,同样,你感觉不到鼠标在手中,你感觉不到指尖下的按键,并且你想要一个控制界面,仍然可以让用户轻松直观地了解系统的状态,以及如何实现他们想要实现的目标。
And ultimately the end goal is that that UX is completely…
最终的最终目标是用户体验完全......
It fades in the background, it becomes something that’s so natural and intuitive that it’s subconscious to the user, and they just should feel like they have basically direct control over the cursor, just does what they want it to do.
它在背景中消失,变得如此自然和直观,以至于用户潜意识里,他们应该感觉自己基本上可以直接控制光标,只是做他们想做的事。
They’re not thinking about the implementation of how to make it do what they want it to do, it’s just doing what they want it to do.
他们并没有考虑如何让它做他们想做的事,而只是做他们想做的事。
Is there some kind of things along the lines of like Fitt’s Law, where you should move the mouse in a certain kind of way that maximizes your chance to hit the target?
是否有一些类似菲特定律的东西,你应该以某种方式移动鼠标,以最大限度地提高击中目标的机会?
5:52:17 I don’t even know what I’m asking, but I’m hoping the intention of my question will land on a profound answer.
我什至不知道我在问什么,但我希望我的问题能够得到一个深刻的答案。
No.
不。
Is there some kind of understanding of the laws of UX when it comes to the context of somebody using their brain to control it that’s different than with a mouse?
当涉及到某人使用大脑控制用户体验的环境时,是否对用户体验法则有某种与鼠标不同的理解?
I think we’re in the early stages of discovering those laws, so I wouldn’t claim to have solved that problem yet, but there’s definitely some things we’ve learned that make it easier for the user to get stuff done.
我认为我们正处于发现这些法则的早期阶段,所以我不会声称已经解决了这个问题,但我们肯定学到了一些东西,可以让用户更轻松地完成工作。
5:52:55 And it’s pretty straightforward when you verbalize it, but it takes a while to actually get to that point, when you’re in the process of debugging the stuff in the trenches.
当你用语言表达时,它非常简单,但当你在战壕中调试东西时,需要一段时间才能真正达到这一点。
5:53:14 One of those things is that any machine learning system that you build has some number of errors, and it matters how those errors translate to the downstream user experience.
其中之一是,您构建的任何机器学习系统都会存在一定数量的错误,这些错误如何转化为下游用户体验很重要。
For example, if you’re developing a search algorithm in your photos, if you search for your friend, Joe, and it pulls up a photo of your friend, Josephine, maybe that’s not a big deal, because the cost of an error is not that high.
例如,如果你正在开发照片中的搜索算法,如果你搜索你的朋友乔,它会调出你朋友约瑟芬的照片,也许这没什么大不了的,因为错误的成本并没有那么高。
In a different scenario, where you’re trying to detect insurance fraud or something like this, and you’re directly sending someone to court because of some machine learning model output, then the errors make a lot more sense to be careful about, you want to be very thoughtful about how those errors translate to downstream effects.
在不同的场景中,当你试图检测保险欺诈或类似的事情时,你会因为一些机器学习模型的输出而直接将某人送上法庭,那么这些错误就更值得小心,你需要非常仔细地考虑这些错误如何转化为下游影响。
5:53:53 The same is true in BCI.
BCI 也是如此。
So for example, if you’re building a model that’s decoding a velocity output from the brain, versus an output where you’re trying to modulate the left click for example, these have sort of different trade-offs of how precise you need to be before it becomes useful to the end user.
例如,如果您正在构建一个解码大脑速度输出的模型,而不是您尝试调制左键单击的输出,那么在对最终用户有用之前,您需要达到的精确度需要进行不同的权衡。
For velocity, it’s okay to be on average correct, because the output of the model is integrated through time.
对于速度来说,平均正确是可以的,因为模型的输出是随时间积分的。
So if the user’s trying to click at position A, and they’re currently position B, they’re trying to navigate over time to get between those two points.
因此,如果用户尝试单击位置 A,而他们当前位于位置 B,则他们会尝试随着时间的推移导航以到达这两点之间。
And as long as the output of the model is on average correct, they can sort of steer it through time, with the user control loop in the mix, they can get to the point they want to get to.
只要模型的输出平均而言是正确的,他们就可以在一定程度上引导它随着时间的推移,在用户控制循环的混合下,他们可以到达他们想要到达的点。
5:54:29 The same is not true of a click.
单击则不然。
For a click, you’re performing it almost instantly, at the scale of neurons firing.
对于点击,您几乎可以立即执行,以神经元放电的规模。
And so you want to be very sure that that click is correct, because a false click can be very destructive to the user.
因此,您需要非常确定该点击是正确的,因为错误的点击可能会对用户造成很大的破坏。
They might accidentally close the tab that they’re trying to do something in, and lose all their progress.
他们可能会意外关闭正在尝试执行某些操作的选项卡,并丢失所有进度。
They might accidentally hit some send button on some text that there’s only half composed and reads funny after.
他们可能会不小心点击一些只写了一半的文本的发送按钮,然后读起来很有趣。
So there’s different sort of cost functions associated with errors in this space, and part of the UX design is understanding how to build a solution that is, when it’s wrong, still useful to the end user.
因此,在这个空间中存在与错误相关的不同类型的成本函数,而用户体验设计的一部分是了解如何构建一个解决方案,该解决方案在出现错误时仍然对最终用户有用。
It’s so fascinating, assigning cost to every action when an error occurs.
当错误发生时,为每个操作分配成本,这太令人着迷了。
5:55:02 So every action, if an error occurs, has a certain cost, and incorporating that into how you interpret the intention, mapping it to the action is really important.
因此,如果发生错误,每个行动都会产生一定的成本,将其纳入您解释意图的方式中,将其映射到行动非常重要。
I didn’t quite, until you said it, realize there’s a cost to sending the text early.
直到你这么说,我才意识到提前发送短信是有代价的。
It’s a very expensive cost.
这是一个非常昂贵的成本。
Yeah, it’s super annoying if you accidentally…
是的,如果你不小心的话,那就太烦人了……
5:55:32 Imagine if your cursor misclicked every once in a while.
想象一下,如果您的光标偶尔会误按一次。
That’s super obnoxious.
这太令人讨厌了。
And the worst part of it is, usually when the user’s trying to click, they’re also holding still, because they’re over the target they want to hit, and they’re getting ready to click, which means that in the datasets that we build, on average is the case that sort of low speeds, or desire to hold still, is correlated with when the user’s attempting to click.
最糟糕的是,通常当用户尝试点击时,他们也会保持静止,因为他们已经超过了想要点击的目标,并且他们正准备点击,这意味着在我们构建的数据集中,平均而言,低速或保持静止的愿望与用户尝试点击时相关。
Wow, that is really fascinating.
哇,这真的很迷人。
People think that, “Oh, a click is a binary signal, this must be super easy to decode.” Well, yes, it is, but the bar is so much higher for it to become a useful thing for the user.
人们认为,“哦,点击是一个二进制信号,这一定非常容易解码。”嗯,是的,确实如此,但是它成为对用户有用的东西的门槛要高得多。
5:55:58 And there’s ways to solve this.
有办法解决这个问题。
I mean, you can sort of take the compound approach of, “Well, let’s take five seconds to click.
我的意思是,你可以采取复合方法,“好吧,让我们花五秒钟的时间来点击。
Let’s take a huge window of time, so we can be very confident about the answer.” But again, world’s best mouse.
让我们花一个很长的时间窗口,这样我们就能对答案非常有信心。”但同样,世界上最好的鼠标。
The world’s best mouse doesn’t take a second to click, or 500 milliseconds to click, it takes five milliseconds to click or less.
世界上最好的鼠标点击并不需要一秒,或者 500 毫秒,而是需要 5 毫秒或更短的时间。
And so if you’re aiming for that kind of high bar, then you really want to solve the underlying problem.
因此,如果您的目标是达到那种高标准,那么您确实想解决根本问题。
So maybe this is a good place to ask about how to measure performance, this whole bits per second.
因此,也许这是询问如何衡量性能(每秒的整体位数)的好地方。
5:56:26 Can you explain what you mean by that?
你能解释一下你的意思吗?
Maybe a good place to start is to talk about Webgrid as a game, as a good illustration of the measurement of performance.
也许一个好的起点是将 Webgrid 作为一个游戏来讨论,作为性能衡量的一个很好的说明。
Yeah.
是的。
5:56:43 Maybe I’ll take one zoom out step there, which is just explaining why we care to measure this at all.
也许我会在那里缩小一步,这只是解释为什么我们关心衡量这一点。
So again, our goal is to provide the user the ability to control the computer as well as I can, and hopefully better.
再说一遍,我们的目标是让用户能够像我一样控制计算机,并希望做得更好。
And that means that they can do it at the same speed as what I can do, it means that they have access to all the same functionality that I have, including all those little details like command tab, command space, all this stuff, they need to be able to do it with their brain, and with the same level of reliability as what I can do with my muscles.
这意味着他们可以以与我相同的速度完成这件事,这意味着他们可以访问我所拥有的所有相同功能,包括所有这些小细节,例如命令选项卡、命令空间等所有这些东西,他们需要能够用他们的大脑来完成这件事,并且具有与我用肌肉所做的相同水平的可靠性。
And that’s a high bar, and so we intend to measure and quantify every aspect of that to understand how we’re progressing towards that goal.
这是一个很高的标准,因此我们打算衡量和量化其中的各个方面,以了解我们如何朝着这一目标取得进展。
5:57:13 There’s many ways to measure BPS by the way, this isn’t the only way, but we present the user a grid of targets, and basically we compute a score which is dependent on how fast and accurate they can select, and then how small are the targets.
顺便说一句,测量 BPS 的方法有很多,这不是唯一的方法,但我们向用户提供了一个目标网格,基本上我们计算一个分数,该分数取决于他们选择的速度和准确度,以及目标的大小。
And the more targets that are on the screen, the smaller they are, the more information you present per click.
屏幕上的目标越多,它们越小,每次点击呈现的信息就越多。
And so if you think about it from information theory point of view, you can communicate across different information theoretic channels, and one such channel is a typing interface, you can imagine, that’s built out of a grid, just like a software keyboard on the screen.
因此,如果您从信息论的角度考虑,您可以通过不同的信息论渠道进行交流,其中一个渠道就是打字界面,您可以想象,它是由网格构建的,就像屏幕上的软件键盘一样。
5:57:41 And bits per second is a measure that’s computed by taking the log of the number of targets on the screen.
每秒位数是通过对屏幕上的目标数量进行对数计算得出的度量。
You can subtract one if you care to model a keyboard, because you have to subtract one for the delete key on the keyboard.
如果您想模拟键盘,则可以减一,因为键盘上的删除键必须减一。
But log of the number of targets on the screen, times the number of correct selections, minus incorrect, divided by some time window, for example, 60 seconds.
但是,记录屏幕上的目标数量,乘以正确选择的数量,减去不正确的选择,再除以某个时间窗口,例如 60 秒。
And that’s sort of the standard way to measure a cursor control task in academia.
这是学术界衡量光标控制任务的标准方法。
And all credit in the world goes to this great professor, Dr. Shenoy of Stanford who came up with that task, and he’s also one of my inspirations for being in the field.
世界上所有的功劳都归功于这位伟大的教授,斯坦福大学的谢诺伊博士,他提出了这项任务,他也是我进入该领域的灵感之一。
So all the credit in the world to him for coming up with a standardized metric to facilitate this kind of bragging rights that we have now to say that Noland is the best in the world at this task with this BCI.
因此,世界上所有的功劳都归功于他提出了一个标准化的指标,以促进这种吹牛的权利,我们现在可以说,诺兰是世界上在这个 BCI 任务上最好的人。
It’s very important for progress that you have standardized metrics that people can compare across.
拥有人们可以比较的标准化指标对于进步非常重要。
Different techniques and approaches, how well does this do?
不同的技术和方法,效果如何?
So big kudos to him and to all the team at Stanford.
向他和斯坦福大学的所有团队表示极大的荣誉。
5:58:29 Yeah, so for Noland, and for me playing this task, there’s also different modes that you can configure this task.
是的,所以对于诺兰和我玩这个任务来说,还有不同的模式可以配置这个任务。
So the Webgrid task can be presented as just sort of a left click on the screen, or you could have targets that you just dwell over, or you could have targets that you left, right click on, you could have targets that are left, right click, middle click, scrolling, clicking and dragging.
因此,Webgrid 任务可以表现为在屏幕上单击左键,或者您可以有您刚刚停留的目标,或者您可以有您左键单击、右键单击的目标,您可以有左键单击、右键单击、中键单击、滚动、单击和拖动的目标。
You can do all sorts of things within this general framework, but the simplest, purest form is just blue targets show up on the screen, blue means left click.
你可以在这个通用框架内做各种各样的事情,但最简单、最纯粹的形式就是屏幕上显示蓝色目标,蓝色意味着左键单击。
That’s the simplest form of the game.
这是游戏最简单的形式。
5:58:56 And the sort of prior records here in academic work and at Neuralink internally with NHPs have all been matched or beaten by Noland with his Neuralink device.
诺兰用他的 Neuralink 设备在学术工作和 Neuralink 内部 NHP 方面创下的先前记录都达到或超过了。
So prior to Neuralink, the world record for a human using device is somewhere between 4.2 to 4.6 BPS, depending on exactly what paper you read and how you interpret it.
因此,在 Neuralink 之前,人类使用设备的世界记录介于 4.2 到 4.6 BPS 之间,具体取决于您阅读的论文以及您如何解释它。
Noland’s current record is 8.5 BPS.
诺兰目前的记录是 8.5 BPS。
and again, this sort of median Neuralinker performance is 10 BPS.
同样,这种 Neuralinker 性能的中值是 10 BPS。
So you can think of it roughly as, he’s 85% the level of control of a median Neuralinker using their cursor to select blue targets on the screen.
所以你可以粗略地认为,他的控制水平相当于中位 Neuralinker 的 85%,使用光标选择屏幕上的蓝色目标。
5:59:35 I think there’s a very interesting journey ahead to get us to that same level of 10 BPS performance.
我认为,要让我们达到 10 BPS 性能的相同水平,未来还有一段非常有趣的旅程。
It’s not the case that the tricks that got us from 4 to 6 BPS, and then 6 to 8 BPS are going to be the ones that get us from 8 to 10.
事实并非如此,那些让我们从 4 BPS 到 6 BPS,然后从 6 到 8 BPS 的技巧将成为让我们从 8 BPS 到 10 BPS 的技巧。
And in my view, the core challenge here is really the labeling problem.
在我看来,这里的核心挑战实际上是标签问题。
It’s how do you understand, at a very, very fine resolution, what the user’s attempting to do?
这就是你如何以非常非常精细的分辨率理解用户试图做什么?
And I highly encourage folks in academia to work on this problem.
我强烈鼓励学术界人士致力于解决这个问题。
What’s the journey with Noland on that quest of increasing the BPS on Webgrid?
Noland 在提高 Webgrid 上的 BPS 的过程中经历了什么?
6:00:01 In March, you said that he selected 89,285 targets in Webgrid.
3月份,你说他在Webgrid中选择了89,285个目标。
So he loves this game, he’s really serious about improving his performance in this game.
所以他喜欢这个游戏,他非常认真地想提高自己在这个游戏中的表现。
So what is that journey of trying to figure out how to improve that performance?
那么,尝试找出如何提高性能的旅程是怎样的呢?
How much can that be done on the decoding side?
解码方面能做到多少?
How much can that be done on the calibration side?
校准方面可以做到多少?
How much can that be done on the Noland side of figuring out how to convey his intention more cleanly?
诺兰德方面可以做多少事情来弄清楚如何更清晰地传达他的意图?
Yeah.
是的。
6:00:36 No, this is a great question.
不,这是一个很好的问题。
So in my view, one of the primary reasons why Noland’s performance is so good is because of Noland.
所以在我看来,诺兰表现这么好的主要原因之一就是因为诺兰。
Noland is extremely focused and very energetic.
诺兰非常专注并且精力充沛。
He’ll play Webgrid sometimes for four hours in the middle of the night.
他有时会在半夜玩四个小时的 Webgrid。
From 2:00 A.M.
从凌晨 2:00 开始
To 6:00 A.M.
至早上 6:00
he’ll be playing Webgrid, just because he wants to push it to the limits of what he can do.
他会玩Webgrid,只是因为他想把它推向他能做的极限。
This is not us asking him to do that, I want to be clear.
我想澄清一下,这并不是我们要求他这样做。
We’re not saying, ” Hey, you should play Webgrid tonight.” We just gave him the game as part of our research, and he is able to play it independently, and practice whenever he wants, and he really pushes hard to push it, the technology’s absolute limit.
我们并不是说,“嘿,你今晚应该玩 Webgrid。”我们刚刚把这个游戏给了他作为我们研究的一部分,他能够独立玩,想练就练,而且他真的很努力地去推动它,技术的绝对极限。
And he views that as his job, really, to make us be the bottleneck.
他确实认为这是他的工作,让我们成为瓶颈。
And boy, has he done that well.
男孩,他做得很好吗?
6:01:16 And so the first thing to acknowledge is that he’s extremely motivated to make this work.
因此,首先要承认的是,他非常有动力去完成这项工作。
I’ve also had the privilege to meet other clinical trial participants from BrainGate and other trials, and they very much shared the same attitude of, they viewed this as their life’s work to advance the technology as much as they can.
我还有幸会见了 BrainGate 和其他试验的其他临床试验参与者,他们的态度非常相似,他们认为这是他们一生的工作,尽其所能地推进技术。
And if that means selecting targets on the screen for four hours from 2:00 A.M.
如果这意味着从凌晨 2:00 开始在屏幕上选择目标长达四个小时
to 6:00 A.M., then so be it.
到早上 6:00,就这样吧。
And there’s something extremely admirable about that that’s worth calling out.
其中有一些非常令人钦佩的事情值得一提。
6:01:42 Okay, so then how do you get from where he started, which is no cursor control to eight BPS?
好吧,那么你如何从他开始的地方(没有光标控制到八个 BPS)开始呢?
I mean, when he started, there’s a huge amount of learning to do on his side and our side to figure out what’s the most intuitive control for him.
我的意思是,当他开始时,他和我们这边都需要做大量的学习来找出对他来说最直观的控制。
And the most intuitive control for him is, you have to find the set intersection of, “Do we have the signal to decode?” So we don’t pick up every single neuron in the motor cortex, which means we don’t have representation for every part of the body.
而对他来说最直观的控制就是,你必须找到设定的交集,“我们有信号可以解码吗?”因此,我们无法获取运动皮层中的每一个神经元,这意味着我们无法代表身体的每个部分。
So there may be some signals that we have better decode performance on than others.
因此,对于某些信号,我们可能比其他信号具有更好的解码性能。
For example, on his left hand, we have a lot of difficulty distinguishing his left ring finger from his left middle finger, but on his right hand, we have a good control and good modulation detected from the neurons that were able to record for his pinky, and his thumb, and his index finger.
例如,在他的左手上,我们很难区分他的左手无名指和左手中指,但在他的右手上,我们从能够记录他的小指、拇指和食指的神经元中检测到良好的控制和良好的调制。
So you can imagine how these different subspaces of modulated activity intersect with what’s the most intuitive for him.
所以你可以想象这些不同的调制活动子空间如何与他最直观的东西相交。
6:02:32 And this has evolved over time, so once we gave him the ability to calibrate models on his own, he was able to go and explore various different ways to imagine controlling the cursor.
这随着时间的推移而发展,所以一旦我们赋予他自己校准模型的能力,他就能够去探索各种不同的方式来想象控制光标。
For example, he can imagine controlling the cursor by wiggling his wrist side to side, or by moving his entire arm, by…
例如,他可以想象通过左右摆动手腕或移动整个手臂来控制光标,通过……
I think at one point he did his feet.
我认为有一次他站稳了脚跟。
He tried a whole bunch of stuff to explore the space of what is the most natural way for him to control the cursor, that at the same time, it’s easy for us to decode-
他尝试了一大堆东西来探索他控制光标最自然的方式,同时我们也很容易解码——
Just to clarify, it’s through the body mapping procedure there, you’re able to figure out which finger he can move?
澄清一下,通过那里的身体映射程序,你能够弄清楚他可以移动哪根手指?
Yes.
是的。
6:03:02 Yeah, that’s one way to do it.
是的,这是一种方法。
Maybe one nuance of the…
也许其中的一个细微差别……
When he’s doing it, he can imagine many more things than we represent in that visual on the screen.
当他这样做时,他可以想象比我们在屏幕上的视觉效果中呈现的更多的东西。
So we show him, sort of abstractly, “Here’s a cursor.
所以我们向他展示,有点抽象,“这是一个光标。
You figure out what works the best for you.” And we obviously have hints about what will work best from that body mapping procedure, of, “We know that this particular action we can represent well.” But it’s really up to him to go and explore and figure out what works the best.
你会发现什么最适合你。”显然,我们已经从身体映射程序中得到了一些关于什么最有效的提示,“我们知道我们可以很好地表现这个特定的动作。”但真正取决于他去探索并找出最有效的方法。
But at which point does he no longer visualize the movement of his body, and is just visualizing the movement of the cursor?
但什么时候他不再观想身体的移动,而只是观想光标的移动呢?
Yeah.
是的。
How quickly does he get there?
他多久能到达那里?
So this happened on a Tuesday.
所以这件事发生在星期二。
6:03:37 I remember this day very clearly, because at some point during the day, it looked like he wasn’t doing super well, it looked like the model wasn’t performing super well, and he was getting distracted, but actually, it wasn’t the case.
这一天我记得很清楚,因为白天的某个时候,看起来他表现得不太好,看起来模型表现得不太好,他走神了,但实际上并非如此。
What actually happened was, he was trying something new, where he was just controlling the cursor, so he wasn’t imagining moving his hand anymore, he was just imagining…
实际发生的情况是,他正在尝试一些新的东西,他只是控制光标,所以他不再想象移动他的手,他只是想象……
I don’t know what it is, some abstract intention to move the cursor on the screen, and I cannot tell you what the difference between those two things are, I truly cannot.
我不知道那是什么,在屏幕上移动光标的一些抽象意图,我无法告诉你这两件事之间有什么区别,我真的不能。
He’s tried to explain it to me before, I cannot give a first-person account of what that’s like.
他之前曾试图向我解释过,但我无法以第一人称的方式描述那是什么样的情况。
But the expletives that he uttered in that moment were enough to suggest that it was a very qualitatively different experience for him to just have direct neural control over a cursor.
但他在那一刻说出的脏话足以表明,对他来说,直接神经控制光标是一种截然不同的体验。
I wonder if there’s a way through UX to encourage a human being to discover that, because he discovered it…
我想知道是否有一种方法可以通过用户体验来鼓励人们发现这一点,因为他发现了......
6:04:23 Like you said to me, that he’s a pioneer.
就像你对我说的,他是一位先驱。
So he discovered that on his own through all of this, the process of trying to move the cursor with different kinds of intentions.
所以他发现,在这一切中,他自己尝试以不同的意图移动光标的过程。
But that is clearly a really powerful thing to arrive at, which is to let go of trying to control the fingers and the hand, and control the actual digital device with your mind.
但这显然是一件非常强大的事情,那就是放弃试图控制手指和手,并用你的思想控制实际的数字设备。
That’s right.
这是正确的。
6:04:56 UX is how it works.
用户体验就是它的工作原理。
And the ideal UX is one that the user doesn’t have to think about what they need to do in order to get it done, it just does it.
理想的用户体验是用户不必考虑他们需要做什么才能完成它,它只是去做。
That is so fascinating.
那真是太迷人了。
6:05:05 But I wonder, on the biological side, how long it takes for the brain to adapt.
但我想知道,从生物学角度来看,大脑需要多长时间才能适应。
So is it just simply learning high level software, or is there a neuroplasticity component where the brain is adjusting slowly?
那么它只是简单地学习高级软件,还是存在大脑缓慢调整的神经可塑性成分?
Yeah.
是的。
6:05:25 The truth is, I don’t know.
事实是,我不知道。
I’m very excited to see with sort of the second participant that I implant, what the journey is like for them, because we’ll have learned a lot more, potentially, we can help them understand and explore that direction more quickly.
我很高兴看到我植入的第二个参与者,他们的旅程是什么样的,因为我们会学到更多,有可能,我们可以帮助他们更快地理解和探索这个方向。
This wasn’t me prompting Noland to go try this, he was just exploring how to use his device and figured it out himself.
这并不是我促使诺兰去尝试这个,他只是在探索如何使用他的设备并自己弄清楚了。
But now that we know that that’s a possibility, that maybe there’s a way to, for example, hint the user, “Don’t try super hard during calibration, just do something that feels natural.” Or, “Just directly control the cursor.
但现在我们知道这是一种可能性,也许有一种方法可以提示用户,“在校准过程中不要太用力,只需做一些感觉自然的事情。”或者,“直接控制光标即可。
Don’t imagine explicit action.” And from there, we should be able to hopefully understand how this is for somebody who has not experienced that before.
不要想象明确的行动。”从这里开始,我们应该能够理解对于以前没有经历过这种情况的人来说这是怎样的。
Maybe that’s the default mode of operation for them, you don’t have to go through this intermediate phase of explicit motions.
也许这就是他们的默认操作模式,你不必经历这个明确动作的中间阶段。
Or maybe if that naturally happens for people, you can just occasionally encourage them to allow themselves to move the cursor.
或者,如果人们自然会发生这种情况,您可以偶尔鼓励他们允许自己移动光标。
Right.
正确的。
Actually, sometimes, just like with a four-minute mile, just the knowledge that that’s possible-
事实上,有时,就像四分钟一英里一样,只要知道这是可能的-
Yes, pushes you to do it.
是的,推动你去做。
Yeah.
是的。
Yeah.
是的。
Enables you to do it, and then it becomes trivial.
让你能够做到,然后它就变得微不足道了。
6:06:21 And then it also makes you wonder, this is the cool thing about humans, once there’s a lot more human participants, they will discover things that are possible.
然后它也让你想知道,这就是人类的酷事,一旦有更多的人类参与者,他们就会发现一些可能的事情。
Yes.
是的。
6:06:32 And share their experiences probably with each other.
并可能互相分享他们的经验。
Yeah, and share.
是的,还有分享。
6:06:34 And that because of them sharing it, they’ll be able to do it.
因为他们分享,他们就能做到。
All of a sudden that’s unlocked for everybody, because just the knowledge sometimes is the thing that enables you to do it.
突然之间,这对每个人来说都是解锁的,因为有时只有知识才能让你做到这一点。
Yeah.
是的。
6:06:46 Just to comment on that too, we’ve probably tried 1,000 different ways to do various aspects of decoding, and now we know what the right subspace is to continue exploring further.
顺便评论一下,我们可能已经尝试了 1,000 种不同的方法来进行解码的各个方面,现在我们知道正确的子空间是什么,可以继续进一步探索。
Again, thanks to Noland and the many hours he’s put into this.
再次感谢诺兰和他为此投入的大量时间。
And so even just that, help constraints, or the beam search of different approaches that we could explore really helps accelerate for the next person the set of things that we’ll get to try on day one, how fast we hopefully get them to use for control, how fast we can enable them to use it independently, and to get value out of the system.
因此,即便如此,帮助约束或我们可以探索的不同方法的波束搜索确实有助于为下一个人加速我们在第一天尝试的一系列事情,我们希望让他们以多快的速度用于控制,我们可以让他们多快地独立使用它,并从系统中获取价值。
So massive hats off to Noland and all the participants that came before to make this technology a reality.
向诺兰和所有之前使这项技术成为现实的参与者致以崇高的敬意。
So how often are the updates to the decoder?
那么解码器的更新频率是多少?
6:07:20 ‘Cause Noland mentioned, “Okay, there’s a new update that we’re working on.” In the stream he said he plays the snake game, because it’s super hard, it’s a good way for him to test how good the update is.
因为诺兰提到,“好的,我们正在开发一个新的更新。”他在直播中说他玩贪吃蛇游戏,因为它超级难,这是他测试更新效果的好方法。
And he says sometimes the update is a step backwards, it’s a constant iteration.
他说,有时更新是一种倒退,是一种不断的迭代。
What does the update entail?
更新意味着什么?
Is it mostly on the decoder side?
主要是在解码器方面吗?
Yeah.
是的。
6:07:48 Couple of comments.
一些评论。
So, one, it’s probably worth drawing distinction between research sessions where we’re actively trying different things to understand what the best approach is, versus independent use, where we wanted to have ability to just go use the device how anybody would want to use their MacBook.
因此,第一,可能值得区分研究会议和独立使用,在研究会议中,我们积极尝试不同的事情来了解什么是最好的方法,在独立使用中,我们希望能够按照任何人想要使用 MacBook 的方式使用设备。
So what he’s referring to is, I think, usually in the context of a research session, where we’re trying many, many different approaches to…
所以我认为他指的是通常在研究会议的背景下,我们正在尝试很多很多不同的方法......
Even unsupervised approaches, like we talked about earlier, to try to come up with better ways to estimate his true intention, and more accurately decoded.
即使是无监督的方法,就像我们之前谈到的那样,试图想出更好的方法来估计他的真实意图,并更准确地解码。
6:08:15 And in those scenarios, we try, in any given session…
在这些情况下,我们会尝试在任何给定的会话中......
He’ll sometimes work for eight hours a day, and so that can be hundreds of different models that we would try in that day.
他有时会一天工作八个小时,因此我们当天会尝试数百种不同的模型。
A lot of different things.
很多不同的事情。
Now, it’s also worth noting that we update the application he uses quite frequently, I think sometimes up to 4 or 5 times a day, we’ll update his application with different features, or bug fixes, or feedback that he’s given us.
现在,还值得注意的是,我们更新他使用的应用程序非常频繁,我想有时一天多达 4 或 5 次,我们会用不同的功能、错误修复或他给我们的反馈来更新他的应用程序。
6:08:39 He’s a very articulate person who is part of the solution, he’s not a complaining person, he says, “Hey, here’s this thing that I’ve discovered is not optimal in my flow.
他是一个非常善于表达的人,是解决方案的一部分,他不是一个抱怨的人,他说,“嘿,我发现这件事在我的流程中并不是最佳的。
Here’s some ideas how to fix it.
这里有一些如何修复它的想法。
Let me know what your thoughts are, let’s figure out how to solve it.” And it often happens that those things are addressed within a couple of hours of him giving us his feedback, that’s the kind of iteration cycle we’ll have.
让我知道你的想法,我们一起想办法解决这个问题。”通常情况下,这些事情在他向我们提供反馈后的几个小时内就得到了解决,这就是我们将要经历的迭代周期。
And so sometimes at the beginning of the session, he’ll give us feedback, and at the end of the session he’s giving us feedback on the next iteration of that process or that setup.
因此,有时在会议开始时,他会给我们反馈,在会议结束时,他会为我们提供有关该流程或设置的下一次迭代的反馈。
That’s fascinating, ’cause one of the things you mentioned that there was 271 pages of notes taken from the BCI sessions, and this was just in March.
这很有趣,因为您提到的其中一件事是 BCI 会议记录有 271 页笔记,而这只是在 3 月份。
6:09:06 So one of the amazing things about human beings that they can provide…
因此,人类可以提供的令人惊奇的事情之一......
Especially ones who are smart, and excited, and all positive and good vibes like Noland, that they can provide feedback, continuous feedback.
尤其是那些像诺兰这样聪明、兴奋、充满积极和良好氛围的人,他们可以提供反馈,持续的反馈。
Yeah.
是的。
6:09:27 Just to brag on the team a little bit, I work with a lot of exceptional people, and it requires the team being absolutely laser-focused on the user, and what will be the best for them.
稍微夸一下团队,我和很多杰出的人一起工作,这要求团队绝对专注于用户,以及什么对他们来说是最好的。
And it requires a level of commitment of, “Okay, this is what the user feedback was.
它需要一定程度的承诺,“好吧,这就是用户的反馈。
I have all these meetings, we’re going to skip that today, and we’re going to do this.” That level of focus and commitment is, I would say, underappreciated in the world.
我要召开所有这些会议,今天我们将跳过这些会议,而我们将这样做。”我想说,这种程度的关注和承诺在世界上并没有得到充分重视。
And also, you obviously have to have the talent to be able to execute on these things effectively, and we have that in loads.
而且,显然你必须拥有能够有效执行这些事情的才能,而我们拥有大量这样的人才。
Yeah, and this is such an interesting space of UX design, because there’s so many unknowns here.
是的,这是用户体验设计的一个非常有趣的领域,因为这里有很多未知数。
6:10:00 And I can tell UX is difficult because of how many people do it poorly.
我可以说用户体验很困难,因为有很多人做得很糟糕。
It’s just not a trivial thing.
这不是一件小事。
Yeah.
是的。
6:10:19 UX is not something that you can always solve by just constant iterating on different things.
用户体验并不总是可以通过不断迭代不同的事物来解决。
Sometimes you really need to step back and think globally, “Am I even in the right sort of minima to be chasing down for a solution?” There’s a lot of problems in which sort of fast iteration cycle is the predictor of how successful you’ll be.
有时你真的需要退后一步,全局思考,“我是否处于寻求解决方案的正确最低限度?”存在很多问题,其中哪种快速迭代周期可以预测您的成功程度。
As a good example, like in an RL simulation for example, the more frequently you get reward, the faster you can progress.
举一个很好的例子,比如在强化学习模拟中,你获得奖励的频率越高,你进步的速度就越快。
It’s just an easier learning problem the more frequently you get feedback.
你收到反馈的频率越高,学习问题就越容易。
But UX is not that way, I mean, users are actually quite often wrong about what the right solution is, and it requires a deep understanding of the technical system, and what’s possible, combined with what the problem is you’re trying to solve.
但用户体验并非如此,我的意思是,用户实际上经常错误地判断什么是正确的解决方案,这需要对技术系统以及可能性的深入了解,并结合您要解决的问题。
Not just how the user expressed it, but what the true underlying problem is to actually get to the right place.
不仅仅是用户如何表达它,而是真正的根本问题是如何真正到达正确的地方。
Yeah, that’s the old stories of Steve Jobs rolling in there, like, “Yeah, the user is a useful signal, but it’s not a perfect signal, and sometimes you have to remove the floppy disc drive.” Or whatever the…
是的,这是史蒂夫·乔布斯的老故事,比如,“是的,用户是一个有用的信号,但它不是一个完美的信号,有时你必须删除软盘驱动器。”或者无论什么……
6:11:04 I forgot all the crazy stories of Steve Jobs making wild design decisions.
我忘记了史蒂夫·乔布斯做出疯狂设计决策的所有疯狂故事。
But there, some of it is aesthetic, that some of it is about the love you put into the design, which is very much a Steve Jobs, Johnny Ive type thing, but when you have a human being using their brain to interact with it, it also is deeply about function, it’s not just aesthetic.
但其中一些是美学的,其中一些是关于你对设计投入的热爱,这在很大程度上是史蒂夫·乔布斯、约翰尼·艾维类型的事情,但是当你让一个人用他们的大脑与之互动时,它也深深地关乎功能,而不仅仅是美学。
And that, you have to empathize with a human being before you, while not always listening to them directly.
而且,你必须同情你面前的人,而不是总是直接倾听他们的声音。
You have to deeply empathize.
你必须深深地感同身受。
It’s fascinating.
这很有趣。
It’s really, really fascinating.
这真的非常非常令人着迷。
And at the same time, iterate, but not iterate in small ways, sometimes a complete…
同时,迭代,但不是以小方式迭代,有时是完整的……
Like rebuilding the design.
就像重建设计一样。
Noland said in the early days the UX sucked, but you improved quickly.
诺兰说,早期的用户体验很糟糕,但你进步得很快。
What was that journey like?
那段旅程是什么样的?
Yeah, I mean, I’ll give you one concrete example.
是的,我的意思是,我给你举一个具体的例子。
6:12:16 So he really wanted to be able to read manga.
所以他真的很想能够阅读漫画。
This is something that he…
这是他……的事情。
I mean, it sounds like a simple thing, but it’s actually a really big deal for him, and he couldn’t do it with his mouse stick.
我的意思是,这听起来像是一件简单的事情,但这对他来说实际上是一件大事,而且他无法用鼠标杆做到这一点。
It wasn’t accessible, you can’t scroll with the mouse stick on his iPad on the website that he wanted to be able to use to read the newest manga, and so-
它无法访问,你无法用他的 iPad 上的鼠标杆滚动他希望能够用来阅读最新漫画的网站,所以 -
Might be a good quick pause to say the mouth stick is the thing he’s using.
可能是一个很好的快速停顿,说嘴棒是他正在使用的东西。
6:12:36 Holding a stick in his mouth to scroll on a tablet.
嘴里叼着一根棍子在平板电脑上滚动。
Right.
正确的。
6:12:44 Yeah.
是的。
You can imagine it’s a stylus that you hold between your teeth.
你可以想象它是一支用牙齿夹着的手写笔。
Yeah, it’s basically a very long stylus.
是的,它基本上是一支很长的手写笔。
It’s exhausting, it hurts, and it’s inefficient.
这很累,很痛苦,而且效率低下。
Yeah.
是的。
6:12:54 And maybe it’s also worth calling out, there are other alternative assisted technologies, but the particular situation Noland’s in, and this is not uncommon, and I think it’s also not well-understood by folks, is that he’s relatively spastic, so he’ll have muscle spasms from time to time.
也许还值得一提的是,还有其他替代辅助技术,但诺兰所处的特殊情况,这并不罕见,而且我认为人们也没有很好地理解,那就是他相对痉挛,所以他会时不时地出现肌肉痉挛。
And so any assistive technology that requires him to be positioned directly in front of a camera, for example, an eye tracker, or anything that requires him to put something in his mouth just is a no-go, ’cause he’ll either be shifted out of frame when he has a spasm, or if he has something in his mouth, it’ll stab him in the face if he spasms too hard.
因此,任何需要他直接站在摄像机前的辅助技术,例如眼动仪,或者任何需要他把东西放进嘴里的辅助技术都是不行的,因为当他痉挛时,他要么会被移出画面,要么如果他嘴里有东西,如果他痉挛得太厉害,就会刺伤他的脸。
So these kinds of considerations are important when thinking about what advantages a BCI has in someone’s life.
因此,在考虑 BCI 对某人的生活有哪些优势时,这些考虑因素非常重要。
If it fits ergonomically into your life in a way that you can use it independently when your caretakers not there, wherever you want to, either in the bed or in the chair, depending on your comfort level and your desire to have pressure source, all these factors matter a lot in how good the solution is in that user’s life.
如果它符合人体工程学,适合您的生活,当您的看护者不在场时,您可以独立使用它,无论您想在哪里,无论是在床上还是在椅子上,取决于您的舒适度和您对压力源的渴望,所有这些因素对于解决方案在用户生活中的效果都非常重要。
6:13:45 So one of these very fun examples is scroll.
这些非常有趣的例子之一就是滚动。
So, again, manga is something he wanted to be able to read, and there’s many ways to do scroll with a BCI.
所以,再说一次,漫画是他想要阅读的东西,并且有很多方法可以通过 BCI 进行滚动。
You can imagine different gestures, for example, the user could do that would move the page.
您可以想象不同的手势,例如,用户可以移动页面。
But scroll is a very fascinating control surface, because it’s a huge thing on the screen in front of you.
但滚动是一个非常迷人的控制界面,因为它在你面前的屏幕上是一个巨大的东西。
So any sort of jitter in the model output, any sort of air in the model output causes an earthquake on the screen.
因此,模型输出中的任何类型的抖动、模型输出中的任何类型的空气都会导致屏幕上发生地震。
You really don’t want to have your mango page that you’re trying to read be shifted up and down a few pixels just because your scroll decoder is not completely accurate.
你真的不希望仅仅因为你的滚动解码器不完全准确而让你尝试阅读的芒果页面上下移动几个像素。
6:14:19 And so this was an example where we had to figure out how to formulate the problem in a way that the errors of the system, whenever they do occur, and we’ll do our best to minimize them, but whenever those errors do occur, that it doesn’t interrupt the qualia, again, of the experience that the user is having.
因此,在这个例子中,我们必须弄清楚如何以一种方式来表述问题,即系统错误无论何时发生,我们都会尽力将其最小化,但无论何时这些错误确实发生,它都不会再次中断用户体验的感受。
It doesn’t interrupt their flow of reading their book.
它不会打断他们阅读书籍的流程。
And so what we ended up building is this really brilliant feature.
所以我们最终构建的是这个非常出色的功能。
This is a teammate named Bruce who worked on this really brilliant work called Quick Scroll.
这是一位名叫 Bruce 的队友,他参与了名为 Quick Scroll 的出色工作。
And Quick Scroll basically looks at the screen, and it identifies where on the screen are scroll bars.
快速滚动基本上是查看屏幕,它识别屏幕上滚动条的位置。
And it does this by deeply integrated with macOS to understand where are the scroll bars actively present on the screen, using the sort of accessibility tree that’s available to macOS apps.
它通过与 macOS 深度集成来实现这一点,以了解滚动条在屏幕上的活跃位置,使用 macOS 应用程序可用的辅助功能树。
And we identified where those scroll bars are, and we provided a BCI scroll bar, and the BCI scroll bar looks similar to a normal scroll bar, but it behaves very differently, in that once you move over to it, your cursor sort of morphs onto it, it sort of attaches or latches onto it.
我们确定了这些滚动条的位置,并提供了一个 BCI 滚动条,BCI 滚动条看起来与普通滚动条类似,但它的行为非常不同,因为一旦你移到它上面,你的光标就会变形到它上面,它会附着或锁定在它上面。
And then once you push up or down, in the same way that you’d use a push to control the normal cursor, it actually moves the screen for you.
然后,一旦您向上或向下推动,就像您使用推动来控制普通光标一样,它实际上会为您移动屏幕。
So it’s basically like remapping the velocity to a scroll action.
所以这基本上就像将速度重新映射到滚动动作一样。
6:15:26 And the reason that feels so natural and intuitive is that when you move over to attach to it feels like magnetic, so you’re sort of stuck onto it, and then it’s one continuous action, you don’t have to switch your imagined movement, you sort of snap onto it, and then you’re good to go.
感觉如此自然和直观的原因是,当你移动到它上面时感觉就像有磁性,所以你有点粘在它上面,然后这是一个连续的动作,你不必切换你想象的运动,你可以卡在它上面,然后你就可以开始了。
You just immediately can start pulling the page down or pushing it up.
您可以立即开始将页面向下拉或向上推。
And even once you get that right, there’s so many little nuances of how the scroll behavior works to make it natural and intuitive.
即使你做到了这一点,滚动行为的工作方式也有很多细微差别,以使其自然和直观。
So one example is momentum.
一个例子就是动量。
When you scroll a page with your fingers on the screen, you actually have some flow, it doesn’t just stop right when you lift your finger up.
当你用手指在屏幕上滚动页面时,你实际上有一些流动,它不会在你抬起手指时就停止。
The same is true with BCI scroll, so we had to spend some time to figure out, “What are the right nuances when you don’t feel the screen under your fingertip anymore?
BCI 滚动也是如此,因此我们必须花一些时间来弄清楚,“当您不再感觉到指尖下的屏幕时,正确的细微差别是什么?
What is the right sort of dynamic, or what’s the right amount of page give, if you will, when you push it to make it flow the right amount for the user to have a natural experience reading their book?”
当你推动它以使其流动到适当的数量以便用户获得自然的阅读体验时,什么是正确的动态类型,或者正确的页面数量是多少?”
6:16:15 I could tell you there’s so many little minutia of how exactly that scroll works, that we spent probably a month getting right, to make that feel extremely natural and easy for the user to navigate.
我可以告诉你,关于滚动的具体工作原理,有很多小细节,我们可能花了一个月的时间来完善,以使用户感觉非常自然且易于导航。
I mean, even the scroll on a smartphone with your finger feels extremely natural and pleasant, and it probably takes an extremely long time to get that right.
我的意思是,即使用手指在智能手机上滚动也感觉非常自然和愉快,而且可能需要很长时间才能做到这一点。
6:16:25 And actually, the same kind of visionary UX design that we were talking about, don’t always listen to the users, but also listen to them, and also have visionary, big, like throw everything out, think from first principles, but also not.
实际上,我们谈论的那种有远见的用户体验设计,不是总是倾听用户的意见,而是也要倾听他们的意见,而且也有远见的、大的,比如扔掉一切,从首要原则出发思考,但也不是。
Yeah, yeah.
是啊是啊。
By the way, it just makes me think that scroll bars on the desktop probably have stagnated, and never taken that…
顺便说一句,它只是让我觉得桌面上的滚动条可能已经停滞了,并且从未采取过……
‘Cause the snap, same as snap to grid, snap to scroll bar action you’re talking about is something that could potentially be extremely useful in the desktop setting, even just for users to just improve the experience.
因为捕捉,就像你所说的捕捉到网格、捕捉到滚动条操作一样,在桌面设置中可能非常有用,甚至只是为了改善用户体验。
‘Cause the current scroll bar experience in the desktop is horrible.
因为当前桌面上的滚动条体验很糟糕。
Yep.
是的。
6:17:19 Agreed.
同意。
It’s hard to find, hard to control, there’s not a momentum, there’s…
很难找到,很难控制,没有动力,有……
6:17:20 And the intention should be clear, when I start moving towards a scroll bar, there should be a snapping to the scroll bar action, but of course…
意图应该很明确,当我开始走向滚动条时,应该有一个捕捉到滚动条的动作,但是当然......
Maybe I’m okay paying that cost, but there’s hundreds of millions of people paying that cost non-stop, but anyway.
也许我可以接受这个成本,但有数亿人在不停地支付这个成本,但无论如何。
But in this case, this is necessary, because there’s an extra cost paid by Noland for the jitteriness, so you have to switch between the scrolling and the reading.
但在这种情况下,这是必要的,因为诺兰为抖动付出了额外的成本,所以你必须在滚动和阅读之间切换。
There has to be a face shift between the two, like when you’re scrolling, you’re scrolling.
两者之间必须有一个面部变化,就像当你滚动时,你就在滚动。
Right, right.
对,对。
6:17:58 So that is one drawback of the current approach.
这是当前方法的一个缺点。
Maybe one other just sort of case study here.
也许另一个只是这里的案例研究。
So, again, UX is how it works, and we think about that holistically, from the…
所以,再说一遍,用户体验就是它的工作原理,我们从整体上思考这一点……
Even the feature detection level of what we detect in the brain, to how we design the decoder, what we choose to decode, to then how it works once it’s being used by the user.
甚至我们在大脑中检测到的特征检测级别,我们如何设计解码器,我们选择解码什么,以及一旦被用户使用它如何工作。
So another good example in that sort of how it works once they’re actually using the decoder, the output that’s displayed on the screen is not just what the decoder says, it’s also a function of what’s going on on the screen.
这是另一个很好的例子,说明一旦他们实际使用解码器,它是如何工作的,屏幕上显示的输出不仅仅是解码器所说的内容,它也是屏幕上发生的事情的函数。
6:18:25 So we can understand, for example, that when you’re trying to close a tab, that very small, stupid little X that’s extremely tiny, which is hard to get precisely hit, if you’re dealing with a noisy output of the decoder, we can understand that that is a small little X you might be trying to hit, and actually make it a bigger target for you.
所以我们可以理解,例如,当你试图关闭一个选项卡时,那个非常小、愚蠢的小X非常小,很难被精确击中,如果你正在处理解码器的嘈杂输出,我们可以理解这是你可能试图击中的一个小X,实际上使它成为你更大的目标。
Similar to how when you’re typing on your phone, if you are used to the iOS keyboard for example, it actually adapts to target size of individual keys based on an underlying language model.
与您在手机上打字类似,如果您习惯使用 iOS 键盘,它实际上会根据底层语言模型来适应各个按键的目标大小。
So it’ll actually understand if I’m typing, “Hey, I’m going to see L.” It’ll make the E key bigger because it knows Lex is the person I’m going to go see.
所以如果我输入“嘿,我要去见 L”,它实际上会理解。它会让 E 键变大,因为它知道 Lex 是我要去见的人。
And so that kind of predictiveness can make the experience much more smooth, even without improvements to the underlying decoder or feature detection part of the stack.
因此,即使没有对底层解码器或堆栈的特征检测部分进行改进,这种预测能力也可以使体验更加流畅。
6:19:07 So we do that with a feature called magnetic targets, we actually index the screen, and we understand, “Okay, these are the places that are very small targets that might be difficult to hit.
因此,我们使用一种称为磁性目标的功能来做到这一点,我们实际上索引了屏幕,并且我们明白,“好吧,这些地方是非常小的目标,可能很难击中。
Here’s the kind of cursor dynamics around that location that might be indicative of the user trying to select it.
这是该位置周围的光标动态,可能表明用户试图选择它。
Let’s make it easier.
让我们让它变得更容易。
Let’s blow up the size of it in a way that makes it easier for the user to sort of snap onto that target.” So all these little details, they matter a lot in helping the user be independent in their day-to-day living.
让我们放大它的大小,让用户更容易捕捉到该目标。”因此,所有这些小细节对于帮助用户在日常生活中独立非常重要。
So how much of the work on the decoder is generalizable to P2, P3, P4, P5 PM?
那么解码器上的工作有多少可以推广到 P2、P3、P4、P5 PM 上呢?
6:19:29 How do you improve the decoder in a way that’s generalizable?
如何以可推广的方式改进解码器?
Yeah, great question.
是的,很好的问题。
6:19:40 So the underlying signal we’re trying to decode is going to look very different in P2 than in P1.
因此,我们尝试解码的底层信号在 P2 中看起来与 P1 中非常不同。
For example, channel number 345 is going to mean something different in user one than it will in user two, just because that electrode that corresponds with channel 345 is going to be next to a different neuron in user one to person user two.
例如,通道号 345 在用户一中的含义与在用户二中的含义不同,只是因为与通道 345 对应的电极将位于用户一与用户二中的不同神经元旁边。
But the approach is the methods, the user experience of how do you get the right behavioral pattern from the user to associate with that neural signal.
但途径是方法,是如何从用户那里获得与该神经信号相关联的正确行为模式的用户体验。
We hope that will translate over multiple generations of users.
我们希望这能够影响多代用户。
6:20:08 And beyond that, it’s very, very possible, in fact, quite likely that we’ve overfit to Noland’s user experience, desires and preferences.
除此之外,事实上,我们很有可能过度适应诺兰的用户体验、愿望和偏好。
And so what I hope to see is that when we get a second, third, fourth participant, that we find what the right wide minimums are that cover all the cases that make it more intuitive for everyone.
因此,我希望看到的是,当我们有第二个、第三个、第四个参与者时,我们会找到正确的最小范围,涵盖所有情况,使每个人都更加直观。
And hopefully, there’s a crosspollination of things, where, “Oh, we didn’t think about that with this user because they can speak.
希望事情能够相互影响,“哦,我们没有考虑到这个用户,因为他们可以说话。
But with this user who just can fundamentally not speak at all, this user experience is not optimal.” Those improvements that we make there should hopefully translate then to even people who can speak but don’t feel comfortable doing so because we’re in a public setting, like their doctor’s office.
但对于这个根本无法说话的用户来说,这种用户体验并不是最佳的。”我们在那里所做的这些改进应该有望转化为那些可以说话但感觉不舒服的人,因为我们是在公共环境中,比如他们的医生办公室。
So the actual mechanism of open-loop labeling, and then closed-loop labeling would be the same, and hopefully can generalize across the different users-
因此,开环标记和闭环标记的实际机制是相同的,并且希望能够在不同用户之间推广-
Correct.
正确。
…
……
6:20:52 as they’re doing the calibration step?
当他们正在进行校准步骤时?
And the calibration step is pretty cool.
校准步骤非常酷。
I mean, that in itself.
我的意思是,这本身就是如此。
The interesting thing about Webgrid, which is closed-loop, it’s fun.
Webgrid 有趣的一点是,它是闭环的,很有趣。
I love it when there’s…
我喜欢它,当有...
They used to be kind of idea of human computation, which is using actions a human would want to do anyway to get a lot of signal from.
它们曾经是人类计算的一种想法,即使用人类想要做的动作来获取大量信号。
And Webgrid is that, a nice video game that also serves as great calibration.
Webgrid 就是这样一款不错的视频游戏,同时也可以起到很好的校准作用。
It’s so funny, I’ve heard this reaction so many times.
太有趣了,我已经听过很多次这样的反应了。
6:21:20 Before the first user was implanted, we had an internal perception that the first user would not find this fun.
在第一个用户被植入之前,我们有一种内在的感觉,第一个用户不会觉得这个有趣。
And so we thought really quite a bit actually about, “Should we build other games that are more interesting for the user, so we can get this kind of data and help facilitate research that’s for long duration and stuff like this?” Turns out that people love this game.
因此,我们实际上思考了很多,“我们是否应该构建其他对用户来说更有趣的游戏,以便我们可以获得此类数据并帮助促进长期研究之类的事情?”事实证明人们喜欢这个游戏。
I always loved it, but I didn’t know that that was a shared perception.
我一直很喜欢它,但我不知道这是一个共同的看法。
Yeah.
是的。
6:21:45 And just in case it’s not clear, Webgrid is…
以防万一不清楚,Webgrid 是……
There’s a grid of let’s say 35 by 35 cells and one of them lights up blue and you have to move your mouse over that and click on it.
假设有一个 35 x 35 个单元格的网格,其中一个单元格亮起蓝色,您必须将鼠标移到该单元格上并单击它。
And if you miss it, it’s red, and…
如果你错过了,它是红色的,而且……
I’ve played this game for so many hours, so many hours.
我已经玩了这个游戏很多个小时了。
And what’s your record you said?
你说的记录是什么?
I think I have the highest at Neuralink right now.
我认为我现在在 Neuralink 的成绩是最高的。
6:22:06 My record’s 17 BPS.
我的记录是 17 BPS。
17 BPS?
17 个基点?
If you imagine that 35 by 35 grid, you’re hitting about 100 trials per minute.
如果您想象 35 x 35 的网格,那么您每分钟大约会进行 100 次试验。
6:22:11 So 100 correct selections in that one minute window.
所以在一分钟的时间内有 100 个正确的选择。
So you’re averaging about between 500, 600 milliseconds per selection.
因此,每次选择的平均时间约为 500 到 600 毫秒。
So one of the reasons I think I struggle with that game is I’m such a keyboard person, so everything is done with via keyboard.
所以我认为我在这款游戏中遇到困难的原因之一是我是一个键盘手,所以一切都是通过键盘完成的。
6:22:22 If I can avoid touching the mouse, it’s great.
如果我能避免碰鼠标,那就太好了。
So how can you explain your high performance?
那么你如何解释你的高绩效呢?
I have a whole ritual I go through when I play Webgrid.
当我玩 Webgrid 时,我有一个完整的仪式。
6:22:36 There’s actually like a diet plan associated with this.
实际上有一个与此相关的饮食计划。
It’s a whole thing.
这是一整件事。
That’s great.
那太棒了。
The first thing is-
第一件事是——
“I have to fast for five days, I have to go up to the mountains.”
“我要斋戒五天,我要上山。”
I mean, the fasting thing is important.
我的意思是,禁食很重要。
6:22:47 So this is like-
所以这就像-
Focuses the mind, yeah.
集中精神,是的。
6:22:49 It’s true, it’s true.
这是真的,这是真的。
So what I do is, I…
所以我要做的是,我……
6:22:51 Actually, I don’t eat for a little bit beforehand, and then I’ll actually eat a ton of peanut butter right before I play, and I get-
事实上,我事先不吃一点东西,然后我实际上会在比赛前吃很多花生酱,然后我得到——
This is a real thing?
这是真事吗?
This is a real thing, yeah.
这是真实的事情,是的。
6:22:59 And then it has to be really late at night, this is, again, a night owl thing I think we share, but it has to be midnight, 2:00 A.M.
然后必须是深夜,我想这又是夜猫子的共同爱好,但必须是午夜,凌晨 2:00。
kind of time window.
一种时间窗口。
And I have a very specific physical position I’ll sit in, which is…
我有一个非常具体的身体位置,那就是……
I was homeschooled growing up, and so I did most of my work on the floor, just in my bedroom or whatever.
我从小就在家接受教育,所以我的大部分工作都是在地板上完成的,就在我的卧室或其他地方。
And so I have a very specific situation-
所以我有一个非常具体的情况 -
On the floor?
在地板上?
…
……
6:23:19 on the floor, that I sit and play.
在地板上,我坐着玩。
And then you have to make sure there’s not a lot of weight on your elbow when you’re playing so you can move quickly.
然后你必须确保在演奏时肘部没有承受太大的重量,这样你才能快速移动。
And then I turn the gain of the cursor, so the speed of the cursor way, way up, so it’s small motions that actually move the cursor.
然后我转动光标的增益,因此光标的速度大大提高,因此实际上移动光标的是小动作。
Are you moving with your wrist, or you’re…
您是用手腕移动,还是……
6:23:29 You’re never-
你从来都不是——
I move with my fingers.
我用手指移动。
6:23:33 So my wrist is almost completely still, I’m just moving my fingers.
所以我的手腕几乎完全静止,我只是移动手指。
You know those…
你知道那些……
6:23:37 Just on a small tangent-
就在一条小切线上——
Yeah.
是的。
…
……
6:23:40 the…
的…
which I’ve been meaning to go down this rabbit hole of people that set the world record in Tetris.
我一直想走进俄罗斯方块世界纪录创造者的这个兔子洞。
Those folks, they’re playing…
那些人,他们正在玩……
There’s a way to…
有一种方法可以...
Did you see this?
你看到这个了吗?
I’ve seen it.
我见过。
6:23:50 All the fingers are moving?
所有的手指都在动吗?
Yeah, you could find a way to do it where it’s using a loophole, like a bug that you can do some incredibly fast stuff.
是的,你可以找到一种利用漏洞的方法来做到这一点,就像一个错误,你可以做一些非常快的事情。
6:23:52 So it’s along that line, but not quite.
所以它是沿着这条线的,但又不完全是。
But you do realize there’ll be a few programmers right now listening to this who’ll fast and eat peanut butter, and be like-
但你确实意识到现在会有一些程序员在听这个,他们会禁食并吃花生酱,然后就像——
Yeah, please track my record.
是的,请跟踪我的记录。
6:24:09 I mean, the reason I did this literally was just because I wanted the bar to be high for the team.
我的意思是,我这样做的原因实际上只是因为我希望团队的标准很高。
The number that we aim for should not be the median performance, it should be able to beat all of us at least, that should be the minimum bar.
我们追求的数字不应该是平均成绩,至少应该能够击败我们所有人,这应该是最低标准。
What do you think is possible, like 20?
你认为什么是可能的,比如 20?
Yeah, I don’t know what the limits…
是的,我不知道限制是什么……
6:24:23 I mean, the limits, you can calculate just in terms of screen refresh rate and cursor immediately jumping to the next target.
我的意思是,您可以根据屏幕刷新率和光标立即跳转到下一个目标来计算限制。
I mean, I’m sure there’s limits before that with just sort of reaction time, and visual perception, and things like this.
我的意思是,我确信在此之前,反应时间、视觉感知等都是有限的。
I would guess it’s below 40, but above 20, somewhere in there is probably the right…
我猜它低于 40,但高于 20,其中的某个地方可能是正确的......
That I’d never to be thinking about.
这是我永远不会去想的。
It also matters how difficult the task is.
任务的难度也很重要。
You can imagine some people might be able to do 10,000 targets on the screen, and maybe they can do better that way.
你可以想象有些人可能能够在屏幕上完成 10,000 个目标,而且也许这样他们可以做得更好。
So there’s some task optimizations you could do to try to boost your performance as well.
因此,您也可以进行一些任务优化来尝试提高您的绩效。
What do you think it takes for Noland to be able to do above 8.5, to keep increasing that number?
您认为诺兰德需要什么才能做到 8.5 以上,并不断增加这个数字?
6:24:55 You said every increase in the number…
你说数量每增加一次……
6:25:00 …
……
to keep increasing that number.
继续增加这个数字。
You said every increase in the number might require different improvements in the system.
你说每次数量的增加都可能需要对系统进行不同的改进。
Yeah.
是的。
6:25:08 The first answer that’s important to say is, I don’t know.
第一个重要的答案是,我不知道。
This is edge of the research so, again, nobody’s gotten to that number before, so what’s next is going to be a heuristic guess from my part.
这是研究的边缘,因此,之前没有人得到过这个数字,所以接下来的内容将是我的启发式猜测。
What we’ve seen historically is that different parts of the stack can compile next to different time points.
我们从历史上看到的是,堆栈的不同部分可以在不同的时间点进行编译。
So when I first joined Neuralink, three years ago or so, one of the major problems was just the latency of the Bluetooth connection.
因此,当我大约三年前第一次加入 Neuralink 时,主要问题之一就是蓝牙连接的延迟。
The radio in the device wasn’t super good, it was an early revision of the implant.
该设备中的无线电不是很好,它是植入物的早期版本。
And it just, no matter how good your decoder was, if your thing is updating every 30 milliseconds or 50 milliseconds, it’s just going to be choppy.
只是,无论你的解码器有多好,如果你的东西每 30 毫秒或 50 毫秒更新一次,它就会变得不稳定。
And no matter how good you are, that’s going to be frustrating and lead to challenges.
无论你有多优秀,这都会令人沮丧并带来挑战。
So at that point, it was very clear that the main challenge is just get the data off the device in a very reliable way such that you can enable the next challenge to be tackled.
因此,在这一点上,很明显,主要的挑战是以非常可靠的方式从设备中获取数据,这样您就可以解决下一个挑战。
6:25:59 And then at some point it was actually the modeling challenge of how do you just build a good mapping, like the supervised learning problem of, you have a bunch of data and you have a label you’re trying to predict, just what is the right neural decoder architecture and hyperparameters to optimize that?
然后在某些时候,这实际上是建模挑战,即如何构建良好的映射,就像监督学习问题一样,你有一堆数据,并且有一个你想要预测的标签,那么正确的神经解码器架构和超参数来优化它是什么?
And that was the problem for a bit, and once you solve that, it became a different bottleneck.
这曾经是一个问题,一旦你解决了这个问题,它就变成了一个不同的瓶颈。
I think the next bottleneck after that was actually just software stability and reliability.
我认为接下来的瓶颈实际上就是软件稳定性和可靠性。
If you have widely varying inference latency in your system or your app just lags out every once in a while, it decreases your ability to maintain and get in a state of flow, and it basically just disrupts your control experience.
如果您的系统中的推理延迟差异很大,或者您的应用程序只是偶尔滞后,那么它会降低您维持和进入流畅状态的能力,并且基本上只会破坏您的控制体验。
And so there’s a variety of different software bugs and improvements we made that basically increased the performance of the system, made it much more reliable, much more stable and led to a state where we could reliably collect data to build better models with.
因此,我们提出了各种不同的软件错误和改进,基本上提高了系统的性能,使其更加可靠、更加稳定,并导致我们可以可靠地收集数据以构建更好的模型。
6:26:49 So that was a bottleneck for a while, it was just the software stack itself.
所以这在一段时间内是一个瓶颈,它只是软件堆栈本身。
If I were to guess right now, there’s two major directions you could think about for improving VPS further.
如果我现在猜的话,你可以考虑两个主要方向来进一步改进 VPS。
The first major direction is labeling.
第一个主要方向是标签。
So labeling is, again, this fundamental challenge of given a window of time where the user is expressing some behavioral intent, what are they really trying to do at the granularity of every millisecond?
因此,标签又是一个基本挑战,即在给定的时间窗口内,用户表达某种行为意图,他们在每毫秒的粒度上真正想要做什么?
And that again, is a task design problem, it’s a UX problem, it’s a machine learning problem, it’s a software problem.
这又是一个任务设计问题、一个用户体验问题、一个机器学习问题、一个软件问题。
It touches all those different domains.
它涉及所有这些不同的领域。
The second thing you can think about to improve BPS further is either completely changing the thing you’re decoding or just extending the number of things that you’re decoding.
要进一步提高 BPS,您可以考虑的第二件事是完全改变您正在解码的内容,或者只是扩展您正在解码的内容的数量。
So this is serving the direction of functionality, basically, you can imagine giving more clicks.
所以这是服务于功能的方向,基本上,你可以想象给予更多的点击。
6:27:33 For example, a left click, a right click, a middle click, different actions like click-and-drag for example, and that can improve the effective bit rate of your communication processes.
例如,左键单击、右键单击、中键单击、单击并拖动等不同操作,都可以提高通信过程的有效比特率。
If you’re trying to allow the user to express themselves through any given communication channel, you can measure that with bits per second.
如果您试图允许用户通过任何给定的通信渠道表达自己,您可以用每秒位数来衡量。
But what actually is measured at the end of the day is how effective are they at navigating their computer?
但最终衡量的实际上是他们使用计算机的效率如何?
So from the perspective of the downstream tasks that you care about, functionality and extending functionality is something we’re very interested in, because not only can it improve the number of BPS, but it can also improve the downstream independence that the user has and the skill and efficiency with which they can operate their computer.
所以从你关心的下游任务来看,功能和扩展功能是我们非常感兴趣的,因为它不仅可以提高BPS的数量,还可以提高用户的下游独立性以及他们操作计算机的技巧和效率。
Would the number of threads increasing also potentially help?
增加线程数量是否也有潜在帮助?
Yes.
是的。
6:28:10 Short answer is yes.
简短的回答是肯定的。
It’s a bit nuanced how that manifests in the numbers.
这在数字上的体现有点微妙。
So what you’ll see is that if you plot a curve of number of channels that you’re using for decode versus either the offline metric of how good you are at decoding or the online metric of in practice how good is the user at using this device, you see roughly a log curve.
因此,您将看到的是,如果您绘制一条用于解码的通道数与您的解码能力的离线指标或用户在使用该设备的实际使用能力的在线指标之间的曲线,您会看到大致一条对数曲线。
So as you move further out in number of channels, you get a corresponding logarithmic improvement in control quality and offline validation metrics.
因此,当您进一步扩大渠道数量时,您会在控制质量和离线验证指标方面获得相应的对数改进。
The important nuance here is that each channel corresponds with a specific represented intention in the brain.
这里重要的细微差别是每个通道都对应于大脑中特定的表示意图。
So for example, if you have a channel 254, it might correspond with moving to the right.
例如,如果您有一个通道 254,它可能对应于向右移动。
Channel 256, might mean move to the left.
256频道,可能意味着向左移动。
If you want to expand the number of functions you want to control, you really want to have a broader set of channels that covers a broader set of imagined movements.
如果您想扩展要控制的功能数量,您确实需要拥有更广泛的通道来涵盖更广泛的想象运动。
You can think of it like Mr. Potato Man actually, if you had a bunch of different imagined movements you could do, how would you map those imagined movements to input to a computer?
实际上,你可以像土豆先生一样思考,如果你有一堆不同的想象动作可以做,你会如何将这些想象的动作映射到计算机的输入?
You could imagine handwriting to output characters on the screen.
您可以想象手写在屏幕上输出字符。
You could imagine just typing with your fingers and have that output text on the screen.
您可以想象只需用手指打字即可在屏幕上输出文本。
You could imagine different finger modulations for different clicks.
您可以想象不同的手指调制不同的点击声。
You can imagine wiggling your big nose for opening some menu or wiggling your big toe to have command tab occur or something like this.
您可以想象摆动您的大鼻子来打开某些菜单,或者摆动您的大脚趾来显示命令选项卡或类似的事情。
So it’s really the amount of different actions you can take in the world depends on how many channels you have on the information content that they carry.
因此,你在世界上可以采取的不同行动的数量实际上取决于你对它们所携带的信息内容拥有多少渠道。
Right, so that’s more about the number of actions.
是的,这更多的是关于动作的数量。
6:29:42 So actually as you increase the number of threads, that’s more about increasing the number of actions you’re able to perform.
因此,实际上,当您增加线程数量时,更多的是增加您能够执行的操作数量。
But one other nuance there that is worth mentioning.
但还有一个细微差别值得一提。
6:29:51 So again, our goal is really to enable a user with paralyzes to control the computer as fast as I can, so that’s BPS, with all the same functionality I have, which is what we just talked about, but then also as reliably as I can.
再说一次,我们的目标实际上是让瘫痪的用户能够尽可能快地控制计算机,这就是 BPS,它具有我所拥有的所有相同功能,这就是我们刚才谈到的,但也尽可能可靠。
And that last point is very related to channel account discussion.
最后一点与频道帐户讨论密切相关。
So as you scale out number of channels, the relative importance of any particular feature of your model input to the output control of the user diminishes, which means that if the neural non-stationarity effect is per channel, or if the noise is independent such that more channels means on average less output effect, then your reliability of your system will improve.
因此,当您扩展通道数量时,模型输入的任何特定特征对用户输出控制的相对重要性就会降低,这意味着如果神经非平稳效应是每个通道的,或者如果噪声是独立的,因此更多的通道意味着平均更少的输出效应,那么系统的可靠性将会提高。
So one core thesis that at least I have is that scaling channel account should improve the reliability system without any work on the decoder itself.
因此,至少我的一个核心论点是,扩展通道帐户应该改进可靠性系统,而无需对解码器本身进行任何工作。
Can you linger on the reliability here?
您还能留恋这里的可靠性吗?
6:30:37 So first of all, when you say non-stationarity of the signal, which aspect are you referring to?
首先,当你说信号的非平稳性时,你指的是哪一方面?
Yeah, so maybe let’s talk briefly what the actual underlying signal looks like.
是的,所以也许让我们简单地谈谈实际的底层信号是什么样的。
6:30:46 So again, I spoke very briefly at the beginning about how when you imagine moving to the right or imagine moving to the left, neurons might fire more or less, and the frequency content that signal, at least in the motor cortex, it’s very correlated with the output intention, the behavioral task that the user is doing.
所以,我在开始时非常简短地谈到,当你想象向右移动或想象向左移动时,神经元可能会或多或少地放电,并且信号的频率内容(至少在运动皮层中)与输出意图、用户正在执行的行为任务非常相关。
You can imagine actually this is not obvious that rate coding, which is the name of that phenomenon, is the only way the brain could represent information.
你可以想象,实际上这并不明显,速率编码(即这种现象的名称)是大脑表示信息的唯一方式。
You can imagine many different ways in which the brain could encode intention, and there’s actually evidence in bats for example, that there’s temporal codes.
你可以想象大脑编码意图的多种不同方式,并且实际上有证据表明,例如,蝙蝠存在时间编码。
So timing codes of exactly when particular neurons fire is the mechanism of information representation.
因此,特定神经元何时放电的精确计时代码是信息表示的机制。
But at least in the motor cortex, there’s substantial evidence that it’s rate coding or at least first order of effect is that it’s rate coding.
但至少在运动皮层中,有大量证据表明它是速率编码,或者至少第一级效应是它是速率编码。
6:31:31 So then if the brain is representing information by changing the frequency of a neuron firing, what really matters is the delta between the baseline state of the neuron and what it looks like when it’s modulated.
因此,如果大脑通过改变神经元放电的频率来表示信息,那么真正重要的是神经元的基线状态与调制时的状态之间的增量。
And what we’ve observed and what has also been observed in academic work is that that baseline rate, if you’re to target the scale, if you imagine that analogy for measuring flour or something when you’re baking, that baseline state of how much the pot weighs is actually different day to day.
我们观察到的以及在学术工作中也观察到的情况是,如果你要瞄准秤,如果你想象在烘焙时测量面粉或其他东西的类比,那么锅的重量的基线状态实际上每天都在不同。
So if what you’re trying to measure is how much rice is in the pot, you’re going to get a different measurement different days because you’re measuring with different pots.
因此,如果您想要测量锅里有多少米,那么在不同的日子您会得到不同的测量结果,因为您使用不同的锅进行测量。
So that baseline rate shifting is really the thing that at least from a first order description of the problem is what’s causing this downstream bias.
因此,至少从问题的一阶描述来看,基线速率变化确实是导致下游偏差的原因。
There can be other effects, not linear effects on top of that, but at least at a very first order description of the problem.
可能还有其他影响,不是除此之外的线性影响,但至少是问题的一阶描述。
That’s what we observed day to day is that the baseline firing rate of any particular neuron or observed on a particular channel is changing.
这就是我们每天观察到的任何特定神经元的基线放电率或在特定通道上观察到的基线放电率正在变化。
So can you just adjust to the baseline to make it relative to the baseline nonstop?
那么是否可以直接调整基线,使其相对于基线不停地变化呢?
Yeah, this is a great question.
是的,这是一个很好的问题。
6:32:29 So with monkeys, we have found various ways to do this.
对于猴子,我们找到了多种方法来做到这一点。
One example way to do this is you ask them to do some behavioral tasks like play the game with a joystick, you measure what’s going on in the brain.
一个示例方法是要求他们执行一些行为任务,例如用操纵杆玩游戏,然后测量大脑中发生的情况。
You compute some mean of what’s going on across all the input features, and you subtract that on the input when you’re doing your BCI session, works super well.
您可以计算所有输入特征的平均值,然后在进行 BCI 会话时在输入上减去该平均值,效果非常好。
For whatever reason, that doesn’t work super well with Noland.
不管出于什么原因,这对诺兰来说效果不太好。
I actually don’t know the full reason why, but I can imagine several explanations.
我实际上不知道完整的原因,但我可以想象几种解释。
6:32:59 One such explanation could be that the context effect difference between some open-loop task and some closed-loop task is much more significant with Noland than it is with the monkey.
一种这样的解释可能是,诺兰的某些开环任务和某些闭环任务之间的上下文效应差异比猴子的显着得多。
Maybe in this open-loop task, he’s watching the Lex Fridman Podcast while he’s doing the task or he’s whistling and listening to music and talking with his friend and ask his mom what’s for dinner while he’s doing this task.
也许在这个开环任务中,他在执行任务时正在观看 Lex Fridman 播客,或者他在执行任务时吹口哨、听音乐、与朋友聊天、问妈妈晚餐吃什么。
So the exact difference in context between those two states may be much larger and thus lead to a bigger generalization gap between the features that you’re normalizing at open-loop time and what you’re trying to use at closed-loop time.
因此,这两种状态之间的上下文的确切差异可能要大得多,从而导致您在开环时间标准化的功能与您在闭环时间尝试使用的功能之间存在更大的泛化差距。
That’s interesting.
那很有意思。
6:33:29 Just on that point, it’s incredible to watch Noland be able to multitask, to do multiple tasks at the same time, to be able to move the mouse cursor effectively while talking and while being nervous because he’s talking in front of [inaudible 06:33:45]
就这一点而言,令人难以置信的是,诺兰能够同时处理多项任务,同时执行多项任务,能够在说话时和紧张时有效地移动鼠标光标,因为他在 [听不清 06:33:45] 面前说话。
Kicking my ass and chest too, yeah.
还踢我的屁股和胸部,是的。
Kicking your ass and talk trash while doing it-
一边踢你的屁股一边说垃圾话——
Yes.
是的。
…
……
6:33:50 so all at the same time.
所以都是同时进行的。
And yes, if you are trying to normalize to the baseline, that might throw everything off.
是的,如果你试图标准化到基线,那可能会让一切都失败。
Boy, is that interesting?
小伙子,这有趣吗?
Maybe one comment on that too.
也许对此也有一个评论。
6:33:59 For folks that aren’t familiar with assistive technology, I think there’s a common belief that, well, why can’t you just use an eye tracker or something like this for helping somebody move a mouse on the screen?
对于那些不熟悉辅助技术的人来说,我认为人们普遍认为,为什么不能使用眼动仪或类似的东西来帮助某人在屏幕上移动鼠标呢?
It’s really a fair question and one that I actually was not confident before Sir Noland that this was going to be a profoundly transformative technology for people like him.
这确实是一个公平的问题,而且在诺兰爵士之前,我实际上并不相信这对于像他这样的人来说将是一项深刻变革的技术。
And I’m very confident now that it will be, but the reasons are subtle.
我现在非常有信心它会是这样,但原因很微妙。
It really has to do with ergonomically how it fits into their life, even if you can just offer the same level of control as what they would have with an eye tracker or with a mouse stick, but you don’t need to have that thing in your face.
这确实与人体工程学如何适应他们的生活有关,即使你可以提供与他们使用眼动仪或鼠标棒相同水平的控制,但你不需要把那个东西放在你的脸上。
You don’t need to be positioned a certain way.
你不需要以某种方式定位。
6:34:34 You don’t need your caretaker to be around to set it up for you.
您不需要您的看护人在场为您进行设置。
You can activate it when you want, how you want, wherever you want.
您可以在您需要的时间、方式、地点激活它。
That level of independence is so game-changing for people.
这种程度的独立性对于人们来说是改变游戏规则的。
It means that they can text a friend at night privately without their mom needing to be in the loop.
这意味着他们可以在晚上私下给朋友发短信,而无需他们的妈妈参与其中。
It means that they can open up and browse the internet at 2:00 AM when nobody’s around to set their iPad up for them.
这意味着他们可以在凌晨 2:00 当周围没有人为他们设置 iPad 时打开并浏览互联网。
This is a profoundly game-changing thing for folks in that situation, and this is even before we start talking about folks that may not be able to communicate at all or ask for help when they want to.
对于处于这种情况的人们来说,这是一个深刻的改变游戏规则的事情,甚至在我们开始谈论那些可能根本无法沟通或在需要时寻求帮助的人们之前。
This can be potentially the only link that they have to the outside world.
这可能是他们与外界的唯一联系。
And yeah, that one doesn’t, I think, need explanation of why that’s so impactful.
是的,我认为不需要解释为什么它如此有影响力。
You mentioned NeuroDecodeR.
您提到了 NeuroDecodeR。
6:35:11 How much machine learning is in the decoder, how much magic, how much science, how much art?
解码器中有多少机器学习、多少魔法、多少科学、多少艺术?
How difficult is it to come up with a decoder that figures out what these sequence of spikes mean?
设计一个解码器来弄清楚这些尖峰序列的含义有多困难?
Yeah, good question.
是的,好问题。
6:35:28 There’s a couple of different ways to answer this, so maybe I’ll zoom out briefly first and then I’ll go down one of the rabbit holes.
有几种不同的方法可以回答这个问题,所以也许我会先简单地缩小范围,然后再深入其中一个兔子洞。
So the zoomed out view is that building the decoder is really the process of building the dataset plus compiling it into the weights, and each of those steps is important.
因此,缩小的观点是,构建解码器实际上是构建数据集并将其编译为权重的过程,并且每个步骤都很重要。
The direction I think of further improvement is primarily going to be in the dataset side of how do you construct the optimal labels for the model.
我认为进一步改进的方向主要是在数据集方面,即如何为模型构建最佳标签。
But there’s an entirely separate challenge of then how do you compile the best model?
但是,还有一个完全独立的挑战,那就是如何编译最佳模型?
And so I’ll go briefly down the second rabbit hole.
因此,我将简要介绍一下第二个兔子洞。
One of the main challenges with designing the optimal model for BCI is that offline metrics don’t necessarily correspond to online metrics.
设计 BCI 最佳模型的主要挑战之一是离线指标不一定对应于在线指标。
It’s fundamentally a control problem.
从根本上来说,这是一个控制问题。
The user is trying to control something on the screen and the exact user experience of how you output the intention impacts their ability to control.
用户试图控制屏幕上的某些内容,而输出意图的确切用户体验会影响他们的控制能力。
So for example, if you just look at validation loss as predicted by your model, there can be multiple ways to achieve the same validation loss.
例如,如果您只查看模型预测的验证损失,则可能有多种方法可以实现相同的验证损失。
6:36:26 Not all of them are equally controllable by the end user.
并非所有这些都可以由最终用户同等控制。
And so it might be as simple as saying, oh, you could just add auxiliary loss terms that help you capture the thing that actually matters.
因此,这可能就像说,哦,您可以添加辅助损失项来帮助您捕获真正重要的事情。
But this is a very complex nuanced process.
但这是一个非常复杂、微妙的过程。
So how you turn the labels into the model is more of a nuanced process than just a standard supervised learning problem.
因此,如何将标签转化为模型不仅仅是一个标准的监督学习问题,更是一个微妙的过程。
One very fascinating anecdote here, we’ve tried many different neural network architectures that translate brain data to velocity outputs, for example.
这是一个非常有趣的轶事,例如,我们尝试了许多不同的神经网络架构,将大脑数据转换为速度输出。
And one example that’s stuck in my brain from a couple of years ago now is at one point, we were using just fully-connected networks to decode the brain activity.
几年前,一个例子一直萦绕在我的脑海中,当时我们只使用完全连接的网络来解码大脑活动。
We tried A-B test where we were measuring the relative performance in online control sessions of one deconvolution over the input signal.
我们尝试了 A-B 测试,测量输入信号的一次反卷积在线控制会话中的相对性能。
So if you imagine per channel you have a sliding window that’s producing some convolved feature, for each of those input sequences for every single channel simultaneously, you can actually get better validation metrics, meaning you’re fitting the data better and it’s generalizing better in offline data if you use this convolutional architecture.
因此,如果您想象每个通道都有一个滑动窗口,可以同时生成一些卷积特征,对于每个通道的每个输入序列,您实际上可以获得更好的验证指标,这意味着如果您使用这种卷积架构,您可以更好地拟合数据,并且在离线数据中可以更好地泛化。
You’re reducing parameters.
你正在减少参数。
It’s a standard procedure when you’re dealing with time series data.
这是处理时间序列数据时的标准过程。
Now it turns out that when using that model online, the controllability was worse, was far worse, even though the offline metrics were better, and there can be many ways to interpret that.
现在事实证明,在线使用该模型时,尽管离线指标更好,但可控性却更差,甚至更差,而且可以有很多方法来解释这一点。
But what that taught me at least was that, hey, it’s at least the case right now that if you were to just throw a bunch of compute at this problem and you were trying to hyperparameter optimize or let some GPT model hard code or come up with or invent many different solutions, if you were just optimizing for loss, it would not be sufficient, which means that there’s still some inherent modeling gap here.
但这至少告诉我的是,嘿,至少现在的情况是,如果你只是在这个问题上投入大量计算,并且尝试超参数优化或让某些 GPT 模型硬编码或提出或发明许多不同的解决方案,如果你只是针对损失进行优化,这是不够的,这意味着这里仍然存在一些固有的建模差距。
There’s still some artistry left to be uncovered here of how to get your model to scale with more compute, and that may be fundamentally a labeling problem, but there may be other components to this as well.
关于如何让模型通过更多计算进行扩展,这里仍然有一些技巧有待发现,这可能从根本上是一个标签问题,但也可能还有其他组成部分。
Is it data constraint at this time, which is what it sounds like?
这时候是不是数据受限了,听起来是这样的?
6:38:11 How do you get a lot of good labels?
如何获得大量优质标签?
Yeah, I think it’s data quality constrained, not necessarily data quantity constrained.
是的,我认为这是数据质量的限制,不一定是数据数量的限制。
But even just the quantity ’cause it has to be trained on the interactions.
但即使只是数量,因为它也必须接受交互方面的训练。
6:38:27 I guess there’s not that many interactions.
我想没有那么多互动。
Yeah, so it depends what version of this you’re talking about.
是的,所以这取决于你正在谈论的是什么版本。
6:38:37 So if you’re talking about, let’s say, the simplest example of just 2D velocity, then I think, yeah, data quality is the main thing.
所以,如果你谈论的是,比如说,2D 速度的最简单的例子,那么我认为,是的,数据质量是最重要的。
If you’re talking about how to build a multi-function output that lets you do all the inputs the computer that you and I can do, then it’s actually a much more sophisticated nuanced modeling challenge because now you need to think about not just when the users are left clicking, but when you’re building the left click model, you also need to be thinking about how to make sure it doesn’t fire when they’re trying to right click or when they’re trying to move the mouse.
如果您正在谈论如何构建一个多功能输出,让您可以完成您和我可以执行的计算机的所有输入,那么这实际上是一个更加复杂的细致入微的建模挑战,因为现在您不仅需要考虑用户何时左键单击,而且当您构建左键单击模型时,您还需要考虑如何确保它在用户尝试右键单击或尝试移动鼠标时不会触发。
6:39:03 So one example of an interesting bug from week one of BCI with Noland was when he moved the mouse, the click signal dropped off a cliff and when he stopped, the click signal went up.
因此,诺兰德 BCI 第一周的一个有趣错误的一个例子是,当他移动鼠标时,点击信号从悬崖上掉下来,当他停下来时,点击信号上升。
So again, there’s a contamination between the two inputs.
同样,两个输入之间存在污染。
Another good example was at one point he was trying to do a left click and drag, and the minute he started moving, the left click signal dropped off a cliff.
另一个很好的例子是,有一次他尝试左键单击并拖动,但在他开始移动的那一刻,左键单击信号就从悬崖上掉了下来。
So again, ’cause some contamination between the two signals, you need to come up with some way to either in the dataset or in the model build robustness against this kind of, you think of it like overfitting, but really it’s just that the model has not seen this kind of variability before.
再说一遍,由于两个信号之间存在一些污染,您需要想出某种方法在数据集中或模型中构建针对这种情况的鲁棒性,您认为这就像过度拟合,但实际上只是模型以前没有见过这种变化。
So you need to find some way to help the model with that.
所以你需要找到一些方法来帮助模型实现这一点。
This is super cool ’cause it feels like all of this is very solvable, but it’s hard.
这太酷了,因为感觉所有这些都可以解决,但很难。
Yes, it is fundamentally an engineering challenge.
是的,这从根本上来说是一个工程挑战。
6:39:46 This is important to emphasize, and it’s also important to emphasize that it may need fundamentally new techniques, which means that people who work on let’s say unsupervised speech classification using CTC loss for example, with internal to Siri, they could potentially have very applicable skills to this.
强调这一点很重要,而且强调它可能需要全新的技术也很重要,这意味着从事使用 CTC 损失的无监督语音分类工作的人,例如 Siri 的内部人员,他们可能拥有非常适用的技能。
So what things are you excited about in the future development of the software stack on Neuralink?
那么,在 Neuralink 上软件堆栈的未来开发中,哪些事情让您感到兴奋呢?
6:40:03 So everything we’ve been talking about, the decoding, the UX?
那么我们一直在谈论的一切,解码,用户体验?
I think there’s something I’m excited about from the technology side and some I’m excited about for understanding how this technology is going to be best situated for entering the world, so I’ll work backwards.
我认为,从技术方面来看,有些事情让我感到兴奋,有些事情让我很兴奋了解这项技术如何最适合进入这个世界,所以我会逆向工作。
6:40:14 On the technology entering the world side of things, I’m really excited to understand how this device works for folks that cannot speak at all, that have no ability to bootstrap themselves into useful control by voice command, for example, and are extremely limited in their current capabilities.
在技术进入世界的方面,我真的很高兴了解这个设备如何为那些根本不会说话的人工作,例如,他们无法通过语音命令引导自己进行有用的控制,并且他们当前的能力极其有限。
I think that will be an incredibly useful signal for us to understand really, what is an existential threat for all startups, which is product market fit.
我认为这将是一个非常有用的信号,让我们真正了解所有初创公司的生存威胁是什么,即产品市场契合度。
Does this device have the capacity and potential to transform people’s lives in the current state?
这个设备是否有能力和潜力改变人们目前的生活?
And if not, what are the gaps?
如果没有,差距是什么?
And if there are gaps, how do we solve them most efficiently?
如果存在差距,我们如何最有效地解决它们?
6:40:56 So that’s what I’m very excited about for the next year or so of clinical trial operations.
这就是我对未来一年左右的临床试验操作感到非常兴奋的地方。
On the technology side, I’m quite excited about basically everything we’re doing.
在技术方面,我对我们所做的一切都感到非常兴奋。
I think it’s going to be awesome.
我认为这会很棒。
The most prominent one I would say is scaling channel account.
我想说的最突出的一个是扩展渠道帐户。
So right now we have a 1,000-channel device.
现在我们有一个 1,000 通道的设备。
The next version we’ll have between 3 and 6,000 channels, and I would expect that curve to continue in the future.
下一个版本我们将拥有 3 到 6,000 个通道,我预计这条曲线将来会继续下去。
And it’s unclear what set of problems will just disappear completely at that scale and what set of problems will remain and require for their focus.
目前还不清楚哪些问题会在这种规模下完全消失,哪些问题将仍然存在并需要他们关注。
And so I’m excited about the clarity of gradient that gives us in terms of the user experiences we choose to focus our time and resources on.
因此,我对梯度的清晰度感到兴奋,它为我们提供了我们选择集中时间和资源的用户体验。
And then also in terms of even things as simple as non-stationarity, does that problem just completely go away at that scale?
然后,即使是像非平稳性这样简单的事情,这个问题在这种规模下是否会完全消失?
Or do we need to come up with new creative UXes still even at that point?
或者我们是否仍然需要提出新的创意用户体验?
6:41:40 And also when we get to that time point, when we start expanding out dramatically the set of functions that you can output from one brain how to deal with all the nuances of both the user experience of not being able to feel the different keys under your fingertips, but still needing to be able to modulate all of them in synchrony to achieve the thing you want.
而且当我们到达那个时间点时,当我们开始大幅扩展您可以从一个大脑输出的一组功能时,如何处理用户体验的所有细微差别,即无法感觉到指尖下的不同按键,但仍然需要能够同步调节所有按键以实现您想要的东西。
And again, you don’t have that appropriate set of feedback loop, so how can you make that intuitive for a user to control a high dimensional control surface without feeling the thing physically?
再说一次,你没有一套合适的反馈循环,那么如何让用户直观地控制高维度的控制表面,而无需物理地感觉到它呢?
I think that’s going to be a super interesting problem.
我认为这将是一个非常有趣的问题。
I’m also quite excited to understand do these scaling laws continue?
我也很高兴了解这些缩放定律是否会继续存在?
As you scale channel count, how much further out do you go before that saturation point is truly hit?
当你扩展通道数量时,在真正达到饱和点之前你还要走多远?
6:42:17 And it’s not obvious today.
今天这一点并不明显。
I think we only know what’s in the interpolation space.
我认为我们只知道插值空间中有什么。
We only know what’s between 0 and 1,024, but we don’t know what’s beyond that.
我们只知道 0 到 1,024 之间的内容,但不知道超出这个范围的内容。
And then there’s a whole range of interesting neuroscience and brain questions, which is, when you stick more stuff in the brain in more places, you get to learn much more quickly about what those brain regions represent.
然后还有一系列有趣的神经科学和大脑问题,也就是说,当你在大脑的更多地方放置更多的东西时,你可以更快地了解这些大脑区域代表什么。
And so I’m excited about that fundamental neuroscience learning, which is also important for figuring out how to most efficiently insert electrodes in the future.
因此,我对基础神经科学学习感到兴奋,这对于弄清楚未来如何最有效地插入电极也很重要。
So yeah, I think all those dimensions I’m really, really excited about.
所以,是的,我认为所有这些方面我都非常非常兴奋。
And that doesn’t even get close to touching the software stack that we work on every single day and what we’re working on right now.
这甚至还没有触及我们每天工作的软件堆栈以及我们现在正在做的事情。
Yeah, it seems virtually impossible to me that 1,000 electrodes is where it saturates.
是的,对我来说,1000 个电极就达到饱和几乎是不可能的。
6:42:49 It feels like this would be one of those silly notions in the future where obviously you should have millions of electrodes and this is where the true breakthroughs happen.
感觉这将是未来那些愚蠢的想法之一,显然你应该拥有数百万个电极,而这才是真正的突破发生的地方。
You tweeted, “Some thoughts are most precisely described in poetry.” Why do you think that is?
你发推文说,“有些想法在诗歌中描述得最准确。”你认为这是为什么?
I think it’s because the information bottleneck of language is pretty steep, and yet you’re able to reconstruct on the other person’s brain more effectively without being literal.
我认为这是因为语言的信息瓶颈相当陡峭,但你可以在对方的大脑中更有效地进行重建,而无需字面意思。
6:43:20 If you can express a sentiment such that in their brain they can reconstruct the actual true underlying meaning and beauty of the thing that you’re trying to get across, the generator function in their brain is more powerful than what language can express.
如果你能表达一种情感,让他们的大脑能够重建你试图传达的事物的真正潜在意义和美感,那么他们大脑中的生成器功能比语言所能表达的功能更强大。
And so the mechanism of poetry is really just to feed or seed that generator function.
因此,诗歌的机制实际上只是为生成器功能提供营养或播种。
So being literal sometimes is a suboptimal compression for the thing you’re trying to convey.
因此,对于您想要传达的内容来说,有时直白地压缩并不是最理想的。
That right.
没错。
6:44:03 And it’s actually in the process of the user going through that generation that they understand what you mean.
实际上,用户在经历那一代人的过程中,他们理解了你的意思。
That’s the beautiful part.
这就是美丽的部分。
It’s also like when you look at a beautiful painting, it’s not the pixels of the painting that are beautiful, it’s the thought process that occurs when you see that, the experience of that, that actually is the thing that matters.
这也就像当你看一幅美丽的画作时,美丽的不是画作的像素,而是当你看到它时发生的思维过程,其中的体验,这实际上才是重要的。
Yeah, it’s resonating with some deep thing within you that the artist also experienced and was able to convey that through the pixels.
是的,它与你内心深处的一些东西产生共鸣,艺术家也经历过,并且能够通过像素传达这一点。
Right.
正确的。
6:44:28 Right.
正确的。
And that’s actually going to be relevant for full-on telepathy.
这实际上与全面的心灵感应有关。
6:44:29 It’s like if you just read the poetry literally, that doesn’t say much of anything interesting.
就好像如果你只是字面地读这首诗,那并没有说出太多有趣的东西。
It requires a human to interpret it.
它需要人类来解释它。
So it’s the combination of the human mind and all the experiences that a human being has within the context of the collective intelligence of the human species that makes that poem make sense and they load that in.
因此,正是人类的思想和人类在人类集体智慧的背景下所拥有的所有经历的结合,才使得这首诗有意义,并且他们将其加载进去。
So in that same way, the signal that carries from human to human meaning may seem trivial, but may actually carry a lot of power because of the complexity of the human mind and the receiving end.
同样地,人与人之间传递的信号可能看起来微不足道,但由于人类思维和接收端的复杂性,实际上可能承载着很大的力量。
Yeah, that’s interesting.
是的,这很有趣。
Who was it?
是谁?
I think Joscha Bach [inaudible 06:45:24] said something about all the people that think we’ve achieved AGI explain why humans like music.
我认为 Joscha Bach [听不清 06:45:24] 对所有认为我们已经实现 AGI 的人说了一些话,解释了为什么人类喜欢音乐。
Oh, yeah.
哦,是的。
And until the AGI likes music, you haven’t achieved AGI or something like this.
在 AGI 喜欢音乐之前,你还没有实现 AGI 或类似的目标。
Do you not think that’s some next token entropy surprise kind of thing going on there?
你不认为这是下一个令牌熵令人惊讶的事情吗?
I don’t know.
我不知道。
I don’t know either.
我也不知道。
6:45:50 I listen to a lot of classical music and also read a lot of poetry and yeah, I do wonder if there is some element of the next token surprise factor going on there.
我听了很多古典音乐,也读了很多诗歌,是的,我确实想知道是否存在下一个象征性惊喜因素的某些元素。
Yeah, maybe.
是的,也许吧。
Cause a lot of the tricks in both poetry and music are basically you have some repeated structure and then you do a twist.
因为诗歌和音乐中的很多技巧基本上都是有一些重复的结构,然后进行扭转。
6:46:00 It’s like, okay, clause 1, 2, 3 is one thing and then clause four is like, “Okay, now we’re onto the next theme,” and they play with exactly when the surprise happens and the expectation of the user.
就像,好吧,第 1、2、3 条是一回事,然后第四条就像“好吧,现在我们进入下一个主题”,它们会在惊喜发生时和用户的期望之间发挥作用。
And that’s even true through history as musicians evolve in music, they take some known structure that people are familiar with and they just tweak it a little bit.
纵观历史,随着音乐家在音乐中的发展,这也是事实,他们采用了人们熟悉的一些已知结构,然后稍微调整一下。
They tweak it and add a surprising element.
他们对其进行了调整并添加了令人惊讶的元素。
This is especially true in classical music heritage, but that’s what I’m wondering.
这在古典音乐遗产中尤其如此,但这正是我想知道的。
Is it all just entropy?
这一切只是熵吗?
So breaking structure or breaking symmetry is something that humans seem to like.
因此,破坏结构或破坏对称性似乎是人类喜欢的事情。
6:46:32 Maybe it’s as simple as that.
也许就这么简单。
Yeah, and great artists copy and knowing which rules to break is the important part, and fundamentally, it must be about the listener of the piece.
是的,伟大的艺术家复制并知道要打破哪些规则是重要的部分,从根本上来说,它必须与作品的听众有关。
6:46:37 Which rule is the right one to break?
哪一条规则最适合打破?
It’s about the audience member perceiving that as interesting.
这是关于观众认为有趣的事情。
What do you think is the meaning of human existence?
你认为人类存在的意义是什么?
There’s a TV show I really like called The West Wing, and in The West Wing there’s a character, he’s the President of the United States who’s having a discussion about the Bible with one of their colleagues.
我非常喜欢一个电视节目,叫做《白宫风云》,《白宫风云》中有一个角色,他是美国总统,他正在和一位同事讨论圣经。
6:47:00 And the colleague says something about the Bible says X, Y, and Z, and the President says, “Yeah, but it also says A, B, C.” The person says, “Well, do you believe the Bible to be literally true?” And the President says, “Yes, but I also think that neither of us are smart enough to understand it.” I think the analogy here for the meaning of life is that largely we don’t know the right question to ask.
同事说了一些关于《圣经》的内容,说是 X、Y 和 Z,总统说:“是的,但它也说是 A、B、C。”那人说:“那么,你相信圣经是真的吗?”总统说:“是的,但我也认为我们都没有足够聪明来理解它。”我认为生命意义的类比是我们很大程度上不知道该问什么问题。
6:47:38 So I think I’m very aligned with the Hitchhiker’s Guide to the Galaxy version of this question, which is basically, if we can ask the right questions, it’s much more likely we find the meaning of human existence.
所以我认为我非常同意《银河系漫游指南》中这个问题的版本,基本上,如果我们能提出正确的问题,我们就更有可能找到人类存在的意义。
So in the short term as a heuristic in the search policy space, we should try to increase the diversity of people asking such questions or generally of consciousness and conscious beings asking such questions.
因此,从短期来看,作为搜索政策空间的启发式方法,我们应该尝试增加提出此类问题的人的多样性,或者增加提出此类问题的意识和有意识存在的多样性。
So again, I think I will take the I don’t know card here, but say I do think there are meaningful things we can do that improve the likelihood of answering that question.
再说一次,我想我会在这里拿“我不知道”卡,但说我确实认为我们可以做一些有意义的事情来提高回答这个问题的可能性。
It’s interesting how much value you assign to the task of asking the right questions.
有趣的是,你对提出正确问题的任务赋予了多少价值。
6:48:13 That’s the main thing, it’s not the answers, it’s the questions.
这是最重要的,不是答案,而是问题。
This point, by the way, is driven home in a very painful way when you try to communicate with someone who cannot speak, because a lot of the time, the last thing to go is they have the ability to somehow wiggle a lip or move something that allows them to say yes or no.
顺便说一下,当你试图与不能说话的人交流时,你会以一种非常痛苦的方式明白这一点,因为很多时候,他们最后要做的就是有能力以某种方式摆动嘴唇或移动一些东西,让他们说“是”或“不是”。
6:48:24 And in that situation, it’s very obvious that what matters is, are you asking them the right question to be able to say yes or no to?
在这种情况下,很明显,重要的是,你是否问了他们正确的问题,以便能够回答“是”或“否”?
Wow, that’s powerful.
哇,太强大了。
6:48:45 Well, Bliss, thank you for everything you do, and thank you for being you, and thank you for talking today.
好吧,布利斯,感谢你所做的一切,感谢你所做的一切,感谢你今天的发言。
Thank you.
谢谢。
Thanks for listening to this conversation with Bliss Chapman.
感谢您收听布利斯·查普曼的对话。
6:48:56 And now, dear friends, here’s Noland Arbaugh, the first human being to have a Neuralink device implanted in his brain.
现在,亲爱的朋友们,诺兰·阿博是第一个在大脑中植入 Neuralink 设备的人。
You had a diving accident in 2016 that left you paralyzed with no feeling from the shoulders down.
您在 2016 年发生了一次潜水事故,导致您瘫痪,肩膀以下失去知觉。
How did that accident change your life?
那次事故如何改变了你的生活?
It was a freak thing that happened.
发生了一件奇怪的事情。
6:49:18 Imagine you’re running into the ocean, although this is a lake, but you’re running into the ocean and you get to about waist high, and then you dive in, take the rest of the plunge under the wave or something.
想象一下,你正在跑进大海,虽然这是一个湖,但你跑进大海,你的高度大约是齐腰高,然后你潜入水中,剩下的时间都在波浪下或其他什么东西下。
That’s what I did, and then I just never came back up.
我就是这么做的,然后我就再也没有回来。
Not sure what happened.
不知道发生了什么。
I did it running into the water with a couple of guys, and so my idea of what happened is really just that I took a stray fist, elbow, knee, foot, something to the side of my head.
我和几个人一起跑进水里,所以我对发生的事情的想法实际上只是我把一个流散的拳头、肘部、膝盖、脚,以及我头一侧的东西。
The left side of my head was sore for about a month afterwards, so I must’ve taken a pretty big knock, and then they both came up and I didn’t.
之后我的左侧头部酸痛了大约一个月,所以我一定是受到了很大的撞击,然后他们都出现了,而我却没有。
And so I was face down in the water for a while.
所以我脸朝下在水里呆了一会儿。
I was conscious, and then eventually just realized I couldn’t hold my breath any longer and I keep saying took a big drink.
我是有意识的,然后最终意识到我不能再屏住呼吸了,我一直说喝了一大杯。
6:50:20 People, I don’t know if they like that I say that.
人们,我不知道他们是否喜欢我这么说。
It seems like I’m making light of it all, but it’s just how I am, and I don’t know.
似乎我对这一切都轻描淡写,但我就是这样,我也不知道。
I am a very relaxed stress-free person.
我是一个非常放松无压力的人。
I rolled with the punches for a lot of this.
对于很多这样的事情,我都采取了应对措施。
I took it in stride.
我泰然处之。
It’s like, “All right, well, what can I do next?
就像,“好吧,接下来我能做什么?
How can I improve my life even a little bit on a day-to-day basis?” At first, just trying to find some way to heal as much of my body as possible to try to get healed, to try to get off a ventilator, learn as much as I could so I could somehow survive once I left the hospital.
我怎样才能改善我的日常生活,哪怕是一点点?”起初,我只是想找到一些方法来尽可能地治愈我的身体,试图摆脱呼吸机,尽可能多地学习,这样我出院后就能以某种方式生存。
And then thank God I had my family around me.
感谢上帝,我的家人在我身边。
If I didn’t have my parents, my siblings, then I would’ve never made it this far.
如果我没有我的父母,我的兄弟姐妹,那么我永远不会走到这一步。
6:51:24 They’ve done so much for me, more than I can ever thank them for, honestly, and a lot of people don’t have that.
他们为我做了很多事情,老实说,我无法感谢他们,而很多人都没有这样做。
A lot of people in my situation, their families either aren’t capable of providing for them or honestly just don’t want to, and so they get placed somewhere in some sort of home.
很多像我这样的人,他们的家人要么没有能力养活他们,要么老实说只是不想养活他们,所以他们被安置在某种家庭的某个地方。
So thankfully, I had my family.
所以庆幸的是,我有我的家人。
I have a great group of friends, a great group of buddies from college who have all rallied around me, and we’re all still incredibly close.
我有一群很棒的朋友,一群很棒的大学好友,他们都聚集在我周围,我们仍然非常亲密。
People always say if you’re lucky, you’ll end up with one or two friends from high school that you keep throughout your life.
人们总是说,如果你幸运的话,你最终会拥有一两个终生的高中朋友。
I have about 10 or 12 from high school that have all stuck around, and we still get together, all of us twice a year.
我有大约 10 到 12 个来自高中的人都留下来了,我们仍然聚在一起,我们所有人每年两次。
We call it the spring series and the fall series.
我们称之为春季系列和秋季系列。
This last one we all did, we dressed up X-Men, so I did a-
这最后一个我们都做了,我们给X战警装扮,所以我做了一个——
Nice.
不错。
…
……
6:52:21 Professor Xavier, and it was freaking awesome.
泽维尔教授,真是太棒了。
It was so good.
真是太好了。
So yeah, I have such a great support system around me, and so being a quadriplegic isn’t that bad.
所以,是的,我周围有一个很好的支持系统,所以四肢瘫痪并不是那么糟糕。
I get waited on all the time.
我一直都在等待。
People bring me food and drinks, and I get to sit around and watch as much TV and movies and anime as I want.
人们给我带来食物和饮料,我可以坐下来随心所欲地观看电视、电影和动漫。
I get to read as much as I want.
我想读多少就读多少。
It’s great.
这很棒。
It’s beautiful to see that you see the silver lining in all of this.
很高兴看到您在这一切中看到了一线希望。
6:52:51 Just going back, do you remember the moment when you first realized you were paralyzed from the neck down?
回想一下,您还记得第一次意识到自己颈部以下瘫痪的那一刻吗?
Yep.
是的。
6:53:03 I was face down in the water when I…
当我……的时候,我脸朝下浸在水里。
whatever, something hit my head.
不管怎样,有什么东西击中了我的头。
I tried to get up and I realized I couldn’t move, and it just clicked.
我试图站起来,但我意识到我无法动弹,然后就咔哒一声。
I’m like, “All right, I’m paralyzed, can’t move.
我想,“好吧,我瘫痪了,动不了。
What do I do?
我该怎么办?
If I can’t get up?
如果我起不来?
I can’t flip over, can’t do anything, then I’m going to drown eventually.” And I knew I couldn’t hold my breath forever, so I just held my breath and thought about it for maybe 10, 15 seconds.
我无法翻身,什么也做不了,最后我就会被淹死。”我知道我不能永远屏住呼吸,所以我只是屏住呼吸,想了大概 10、15 秒。
I’ve heard from other people that on lookers, I guess the two girls that pulled me out of the water were two of my best friends.
我听其他人说,从外表来看,我猜把我从水里拉出来的两个女孩是我最好的两个朋友。
They were lifeguards, and one of them said that it looked like my body was shaking in the water like I was trying to flip over and stuff, but I knew.
他们是救生员,其中一位说,看起来我的身体在水中摇晃,就像我想翻身之类的,但我知道。
I knew immediately, and I realized that that’s what my situation was from here on out.
我立刻就明白了,我意识到从现在开始我的处境就是这样。
6:54:08 Maybe if I got to the hospital, they’d be able to do something.When I was in the hospital right before surgery, I was trying to calm one of my friends down.
也许如果我到了医院,他们就能做点什么。当我在手术前在医院时,我试图让我的一位朋友平静下来。
I had brought her with me from college to camp, and she was just bawling over me, and I was like, “Hey, it’s going to be fine.
我把她从大学带到露营地,她只是对着我大哭,我当时想,“嘿,一切都会好起来的。
Don’t worry.” I was cracking some jokes to try to lighten the mood.
别担心。”我讲了一些笑话试图缓解气氛。
The nurse had called my mom, and I was like, “Don’t tell my mom.
护士给我妈妈打电话,我说:“别告诉我妈妈。
She’s just going to be stressed out.
她只会感到压力很大。
Call her after I’m out of surgery ’cause at least she’ll have some answers then, whether I live or not, really.” And I didn’t want her to be stressed through the whole thing, but I knew.
手术结束后给她打电话,因为不管我是否还活着,至少她会得到一些答案,真的。”我不想让她在整个过程中感到压力,但我知道。
6:54:44 And then when I first woke up after surgery, I was super drugged up.
然后当我手术后第一次醒来时,我就被下了迷药。
They had me on fentanyl three ways, which was awesome.
他们让我用三种方式服用芬太尼,这太棒了。
I don’t recommend it, but I saw some crazy stuff on that fentanyl, and it was still the best I’ve ever felt on drugs, medication, sorry, on medication.
我不推荐它,但我在芬太尼上看到了一些疯狂的东西,这仍然是我在药物、药物治疗方面感觉最好的,对不起,在药物治疗方面。
I remember the first time I saw my mom in the hospital, I was just bawling.
我记得我第一次在医院见到妈妈时,我只是嚎啕大哭。
I had ventilator in.
我有呼吸机。
I couldn’t talk or anything, and I just started crying because it was more like seeing her…
我无法说话,也无法说话,我就开始哭泣,因为这更像是看到她……
The whole situation obviously was pretty rough, but it was just seeing her face for the first time was pretty hard.
整个情况显然很艰难,但光是第一次看到她的脸就已经很艰难了。
But yeah, I never had a moment of, “Man, I’m paralyzed.
但是,是的,我从未有过这样的时刻:“伙计,我瘫痪了。
This sucks.
这太糟糕了。
I don’t want to be around anymore.” It was always just, “I hate that I have to do this, but sitting here and wallowing isn’t going to help.”
我不想再在这附近了。”它总是只是,“我讨厌我必须这样做,但坐在这里打滚是没有帮助的。”
So immediate acceptance.
于是立即接受。
Yeah.
是的。
6:55:58 Yeah.
是的。
Has there been low points along the way?
一路上有过低谷吗?
Yeah, yeah, sure.
是的,是的,当然。
6:56:03 There are days when I don’t really feel like doing anything.
有时候我真的不想做任何事。
Not so much anymore.
不再那么多了。
Not for the last couple of years I don’t really feel that way.
过去几年我确实没有这种感觉。
I’ve more so just wanted to try to do anything possible to make my life better at this point.
我现在只想尽一切可能让我的生活变得更好。
But at the beginning, there were some ups and downs.
但一开始,也经历了一些坎坷。
There were some really hard things to adjust to.
有一些事情确实很难适应。
First off, just the first couple months, the amount of pain I was in was really, really hard.
首先,就在最初的几个月,我所承受的痛苦真的非常非常大。
I remember screaming at the top of my lungs in the hospital because I thought my legs were on fire, and obviously I can’t feel anything, but it’s all nerve pain.
我记得在医院里我大声尖叫,因为我觉得我的腿着火了,显然我什么也感觉不到,但这都是神经痛。
And so that was a really hard night.
所以那是一个非常艰难的夜晚。
I asked them to give me as much pain meds as possible, but they’re like, “You’ve had as much as you can have, so just deal with it.
我要求他们给我尽可能多的止痛药,但他们说,“你已经吃够了,所以就处理它吧。
Go to a happy place,” sort of thing.
去一个快乐的地方”之类的事情。
So that was a pretty low point.
所以这是一个相当低的点。
6:56:59 And then every now and again, it’s hard realizing things that I wanted to do in my life that I won’t be able to do anymore.
然后时不时地,很难意识到我一生中想做的事情我将无法再做。
I always wanted to be a husband and father, and I just don’t think that I could do it now as a quadriplegic.
我一直想成为一名丈夫和父亲,但我认为我现在作为一个四肢瘫痪者无法做到这一点。
Maybe it’s possible, but I’m not sure I would ever put someone I love through that, having to take care of me and stuff.
也许有可能,但我不确定我会让我爱的人经历这样的事情,不得不照顾我之类的。
Not being able to go out and play sports, I was a huge athlete growing up, so that was pretty hard.
由于无法出去运动,我在成长过程中是一名出色的运动员,所以这非常困难。
Little things too, when I realized I can’t do them anymore.
当我意识到我不能再做这些事情时,也是如此。
There’s something really special about being able to hold a book and smell a book, the feel, the texture, the smell as you turn the pages, I just love it and I can’t do it anymore, and it’s little things like that.
能够拿着一本书闻一本书的味道真的很特别,翻页时的感觉、质地、气味,我就是喜欢它,但我不能再这样做了,就是这样的小事。
6:57:53 The two-year mark was pretty rough.
两年的时间相当艰难。
Two years is when they say you will get back basically as much as you’re ever going to get back as far as movement and sensation goes.
他们说,两年后,你基本上就能恢复到运动和感觉方面的恢复程度。
And so for the first two years, that was the only thing on my mind was try as much as I can to move my fingers, my hands, my feet, everything possible to try to get sensation and movement back.
所以在最初的两年里,我脑子里唯一想做的就是尽可能多地移动我的手指、我的手、我的脚,尽一切可能尝试恢复感觉和运动。
And then when the two-year mark hit, so June 30, 2018, I was really sad that that’s where I was, and then just randomly here and there, but I was never depressed for long periods of time.
然后,当两年的大关到来时,2018 年 6 月 30 日,我真的很伤心,那就是我所处的位置,然后只是随意地到处走走,但我从来没有长时间感到沮丧。
Just it never seemed worthwhile to me.
只是对我来说这似乎不值得。
What gave you strength?
是什么给了你力量?
My faith.
我的信仰。
6:58:47 My faith in God was a big one.
我对上帝有很大的信心。
My understanding that it was all for purpose, and even if that purpose wasn’t anything involving Neuralink, even if that purpose was…
我的理解是这一切都是有目的的,即使这个目的与 Neuralink 无关,即使这个目的是……
There’s a story in the Bible about Job, and I think it’s a really, really popular story about how Job has all of these terrible things happen to him, and he praises God throughout the whole situation.
圣经中有一个关于约伯的故事,我认为这是一个非常非常流行的故事,讲述了约伯如何遭遇所有这些可怕的事情,而他在整个情况下赞美上帝。
I thought, and I think a lot of people think for most of their lives that they are Job, that they’re the ones going through something terrible, and they just need to praise God through the whole thing and everything will work out.
我想,我想很多人一生中的大部分时间都认为他们是约伯,他们正在经历可怕的事情,他们只需要在整个事情中赞美上帝,一切都会好起来的。
6:59:28 At some point after my accident, I realized that I might not be Job, that I might be one of his children that gets killed or kidnapped or taken from him.
在我发生事故后的某个时刻,我意识到我可能不是约伯,我可能是他的孩子之一,被杀、绑架或从他身边夺走。
And so it’s about terrible things that happen to those around you who you love.
所以它是关于发生在你周围你所爱的人身上的可怕的事情。
So maybe in this case, my mom would be Job and she has to get through something extraordinarily hard, and I just need to try and make it as best as possible for her because she’s the one that’s really going through this massive trial.
所以也许在这种情况下,我的妈妈就是乔布,她必须经历一些异常艰难的事情,我只需要尽力为她做到最好,因为她是真正正在经历这一巨大考验的人。
7:00:01 …
……
she’s the one that’s really going through this massive trial and that gave me a lot of strength, and obviously my family.
她是真正经历过这一巨大考验的人,这给了我很大的力量,当然还有我的家人。
My family and my friends, they give me all the strength that I need on a day-to-day basis.
我的家人和朋友,他们给了我日常所需的全部力量。
So it makes things a lot easier having that great support system around me.
因此,有我周围强大的支持系统让事情变得容易多了。
From everything I’ve seen of you online, your streams and the way you are today, I really admire, let’s say your unwavering positive outlook on life.
从我在网上看到的你的一切、你的直播以及你今天的样子,我真的很钦佩,比如说你坚定不移的积极的人生观。
7:00:20 Has that always been this way?
一直都是这样吗?
Yeah, yeah.
是啊是啊。
7:00:32 I mean, I’ve just always thought I could do anything I ever wanted to do.
我的意思是,我一直认为我可以做任何我想做的事情。
There was never anything too big.
从来没有什么太大的事情。
Whatever I set my mind to, I felt like I could do it.
无论我下定决心做什么,我都觉得我能做到。
I didn’t want to do a lot.
我不想做太多事。
I wanted to travel around and be sort of like a gypsy and go work odd jobs.
我想要到处旅行,像吉普赛人一样,打零工。
I had this dream of traveling around Europe and being like, I don’t know, a shepherd in Wales or Ireland, and then going and being a fisherman in Italy, doing all of these things for a year.
我有一个梦想,环游欧洲,成为威尔士或爱尔兰的牧羊人,我不知道,然后去意大利当渔夫,做所有这些事情一年。
It’s such cliche things, but I just thought it would be so much fun to go and travel and do different things.
这是很陈词滥调的事情,但我只是觉得去旅行和做不同的事情会很有趣。
7:01:17 And so I’ve always just seen the best in people around me too, and I’ve always tried to be good to people.
所以我也总是看到周围人最好的一面,而且我也一直努力对人友善。
And growing up with my mom too, she’s like the most positive energetic person in the world, and we’re all just people people.
和我妈妈一起长大,她就像世界上最积极、最有活力的人,而我们都只是普通人。
I just get along great with people.
我只是与人相处得很好。
I really enjoy meeting new people, and so I just wanted to do everything.
我真的很喜欢结识新朋友,所以我想做一切。
This is kind of just how I’ve been.
我就是这样。
It’s just great to see that cynicism didn’t take over given everything you’ve been through.
很高兴看到你所经历的一切并没有被愤世嫉俗所占据。
Yeah.
是的。
Was that a deliberate choice you made, that you’re not going to let this keep you down?
这是你经过深思熟虑后做出的选择吗?你不会因此而沮丧吗?
Yeah, a bit.
是的,有一点。
7:02:01 Also, it’s just kind of how I am.
而且,这就是我的性格。
I just, like I said, I roll with the punches with everything.
我只是,就像我说的,我对一切都从容应对。
I always used to tell people I don’t stress about things much, and whenever I’d see people getting stressed, I would just say, “It’s not hard just don’t stress about it and that’s all you need to do.
我总是告诉人们我不会对事情有太多压力,每当我看到人们有压力时,我就会说,“这并不难,只是不要压力,这就是你需要做的。
And they’re like, “That’s not how that works.” I’m like, “It works for me.
他们说,“事情不是这样的。”我想,“这对我有用。
Just don’t stress and everything will be fine.
只要不要有压力,一切都会好起来的。
Everything will work out.” Obviously not everything always goes well, and it’s not like it all works out for the best all the time, but I just don’t think stress has had any place in my life since I was a kid.
一切都会解决的。”显然,并不是所有事情总是一帆风顺,也不是所有事情都一直都是最好的,但我只是不认为压力从我小时候起就在我的生活中占有一席之地。
What was the experience like of you being selected to be the first human being to have a Neuralink device implanted in your brain?
您被选为第一个在大脑中植入 Neuralink 设备的人是什么感觉?
7:02:44 Were you scared?
你害怕吗?
Excited?
兴奋吗?
No, no.
不,不。
7:02:54 It was cool.
很酷。
I was never afraid of it.
我从来不害怕它。
I had to think through a lot.
我不得不考虑很多。
Should I do this?
我应该这样做吗?
Be the first person?
成为第一人?
I could wait until number two or three and get a better version of the Neuralink.
我可以等到第二名或第三名,然后获得更好版本的 Neuralink。
The first one might not work.
第一个可能行不通。
Maybe it’s actually going to kind of suck.
也许它实际上会有点糟糕。
It’s going to be the worst version ever in a person, so why would I do the first one?
这将是一个人有史以来最糟糕的版本,那么我为什么要做第一个呢?
I’ve already kind of been selected?
我已经被选中了?
I could just tell them, “Okay, find someone else, and then I’ll do number two or three.” I’m sure they would let me, they’re looking for a few people anyways, but ultimately I was like, I don’t know?
我可以告诉他们,“好吧,找其他人,然后我会做第二或第三件事。”我确信他们会让我,无论如何他们正在寻找一些人,但最终我想,我不知道?
There’s something about being the first one to do something.
成为第一个做某事的人是有道理的。
It’s pretty cool.
非常酷。
I always thought that if I had the chance that I would like to do something for the first time, this seemed like a pretty good opportunity.
我一直认为,如果我有机会第一次想做某事,这似乎是一个很好的机会。
And I was never scared.
我从来不害怕。
7:03:51 I think my faith had a huge part in that.
我认为我的信仰在其中起了很大的作用。
I always felt like God was preparing me for something.
我总觉得上帝正在为我做一些准备。
I almost wish it wasn’t this, because I had many conversations with God about not wanting to do any of this as a quadriplegic.
我几乎希望不是这样,因为我与上帝进行过多次对话,表示我不想作为一个四肢瘫痪的人做这些事。
I told Him, “I’ll go out and talk to people.
我告诉他:“我要出去和人们交谈。
I’ll go out and travel the world and talk to stadiums, thousands of people, give my testimony.
我将出去环游世界,与体育场馆、成千上万的人交谈,提供我的见证。
I’ll do all of it, but heal me first.
我会做这一切,但先治愈我。
Don’t make me do all of this in a chair.
别让我坐在椅子上做这一切。
That sucks.” And I guess He won that argument.
太糟糕了。”我猜他赢了这场争论。
I didn’t really have much of a choice.
我真的没有太多选择。
I always felt like there was something going on.
我总感觉有什么事情要发生。
And to see how, I guess easily I made it through the interview process and how quickly everything happened, how the stars sort of aligned with all of this.
我想看看我是如何轻松通过面试过程的,以及一切发生的速度有多快,明星们是如何与所有这一切保持一致的。
It just told me as the surgery was getting closer, it just told me that it was all meant to happen.
它只是告诉我,随着手术的临近,它只是告诉我,这一切都是注定要发生的。
7:05:02 It was all meant to be, and so I shouldn’t be afraid of anything that’s to come.
这一切都是命中注定的,所以我不应该害怕即将发生的任何事情。
And so I wasn’t.
所以我不是。
I kept telling myself like, “You say that now, but as soon as the surgery comes, you’re probably going to be freaking out.
我不断地告诉自己,“你现在这么说,但一旦手术到来,你可能会吓坏了。
You’re about to have brain surgery.” And brain surgery is a big deal for a lot of people, but it’s an even bigger deal for me.
你即将接受脑部手术。”脑部手术对很多人来说都是一件大事,但对我来说更是一件大事。
It’s all I have left.
这是我所剩下的一切。
The amount of times I’ve been like, “Thank You, God, that you didn’t take my brain and my personality and my ability to think, my love of learning, my character, everything.
我有很多次这样说:“上帝啊,谢谢你,你没有夺走我的大脑、我的个性、我的思考能力、我对学习的热爱、我的性格,一切。
Thank You so much.
太感谢了。
As long as You left me that, then I think I can get by.” And I was about to let people go root around in there like, “Hey, we’re going to go put some stuff in your brain.
只要你把那个留给我,我想我就能过得去。”我想让人们在那里扎根,比如,“嘿,我们要把一些东西放进你的大脑里。
Hopefully it works out.” And so it was something that gave me pause, but like I said, how smoothly everything went.
希望一切顺利。”这让我犹豫了,但就像我说的,一切进展得多么顺利。
7:05:54 I never expected for a second that anything would go wrong.
我从来没有想到会出现任何问题。
Plus the more people I met on the Barrow side and on the Neuralink side, they’re just the most impressive people in the world.
再加上我在 Barrow 方面和 Neuralink 方面遇到的人越多,他们就是世界上最令人印象深刻的人。
I can’t speak enough to how much I trust these people with my life and how impressed I am with all of them.
我无法用言语表达我对这些人的信任以及他们给我留下的深刻印象。
And to see the excitement on their faces, to walk into a room and, roll into a room and see all of these people looking at me like, “We’re so excited.
看到他们脸上的兴奋,走进一个房间,滚进一个房间,看到所有这些人都看着我,就像,“我们太兴奋了。
We’ve been working so hard on this and it’s finally happening.” It’s super infectious and it just makes me want to do it even more.
我们为此付出了巨大的努力,终于实现了。”它极具感染力,让我更加想做。
And to help them achieve their dreams, I don’t know, it’s so rewarding and I’m so happy for all of them, honestly.
帮助他们实现梦想,我不知道,这是非常有意义的,说实话,我为他们所有人感到高兴。
What was the day of surgery like?
手术当天是什么样的?
7:06:45 When did you wake up?
你什么时候起床的?
What’d you feel?
你有什么感觉?
Minute-by-minute.
一分钟一分钟。
Were you freaking out?
你吓坏了吗?
No, no.
不,不。
7:06:54 I thought I was going to, but as surgery approached the night before, the morning of, I was just excited.
我以为我会这么做,但随着手术前一天晚上、第二天早上的临近,我感到很兴奋。
I was like, “Let’s make this happen.” I think I said that, something like that to Elon on the phone.
我当时想,“让我们实现这一点吧。”我想我在电话里对埃隆说过类似的话。
Beforehand we were FaceTiming, and I was like, “Let’s rock and roll.” And he’s like, “Let’s do it.” I don’t know.
之前我们进行了 FaceTime 通话,我当时想,“让我们一起摇滚吧。”他说:“我们就这么做吧。”我不知道。
I wasn’t scared.
我并不害怕。
So we woke up.
于是我们就醒了。
I think we had to be at the hospital at 5:30 AM.
我想我们必须在凌晨 5:30 到达医院。
I think surgery was at 7:00 AM So we woke up pretty early.
我记得手术是在早上 7:00 所以我们醒得很早。
I’m not sure much of us slept that night.
我不确定那天晚上我们中有多少人睡着了。
Got to the hospital 5:30, went through all the pre-op stuff.
5点30分到达医院,完成了所有术前准备。
Everyone was super nice.
每个人都超级好。
Elon was supposed to be there in the morning, but something went wrong with his plane, so we ended up FaceTiming.
埃隆本来应该早上去那里,但他的飞机出了问题,所以我们最终通过 FaceTime 通话。
That was cool.
太酷了。
I had one of the greatest one-liners of my life after that phone call.
在那通电话之后,我说出了我一生中最伟大的俏皮话之一。
Hung up with him.
和他挂了电话。
There were 20 people around me and I was like, “I just hope he wasn’t too starstruck talking to me.”
我周围有 20 个人,我当时想,“我只是希望他跟我说话时不要太追星。”
Nice.
不错。
And yeah, it was good.
是的,这很好。
Well done.
干得好。
7:07:56 Well done.
干得好。
Did you write that ahead of time it just came to you?
你是提前写的吗?
No.
不。
7:08:02 No, it just came to me.
不,它只是出现在我身上。
I was like, “This seems right.” Went into surgery.
我当时想,“这似乎是对的。”进入手术室。
I asked if I could pray right beforehand, so I prayed over the room.
我问是否可以提前祈祷,所以我在房间里祈祷。
I asked God if He would be with my mom in case anything happened to me and just to calm her nerves out there.
我问上帝,万一我发生什么事,他是否会和我妈妈在一起,安抚她的紧张情绪。
Woke up, played a bit of a prank on my mom.
醒了,跟妈妈开了个玩笑。
I don’t know if you’ve heard about it?
不知道你听说过吗?
Yeah, I read about it.
是的,我读到过。
Yeah, she was not happy.
是的,她不高兴。
Can you take me through the prank?
你能带我经历这个恶作剧吗?
Yeah.
是的。
7:08:29 This is something-
这是某事——
Do you regret doing that now?
你现在后悔这样做了吗?
…
……
7:08:31 No, no, not one bit.
不,不,一点也没有。
It was something I had talked about ahead of time with my buddy Bane.
这是我提前和我的好友贝恩讨论过的事情。
I was like, “I would really like to play a prank on my mom.” Very specifically, my mom.
我当时想,“我真的很想对我妈妈开个恶作剧。”非常具体,我的妈妈。
She’s very gullible.
她很容易受骗。
I think she had knee surgery once even, and after she came out of knee surgery, she was super groggy.
我想她甚至做过一次膝盖手术,膝盖手术结束后,她非常昏昏沉沉。
She’s like, “I can’t feel my legs.” And my dad looked at her.
她说,“我感觉不到我的腿了。”我爸爸看着她。
He was like, “You don’t have any legs.
他说:“你没有腿。
They had to amputate both your legs.” And we just do very mean things to her all the time.
他们不得不截掉你的双腿。”我们总是对她做一些非常卑鄙的事情。
I’m so surprised that she still loves us.
我很惊讶她仍然爱我们。
7:09:15 But right after surgery, I was really worried that I was going to be too groggy, not all there.
但手术后,我真的很担心我会变得太昏昏沉沉,不舒服。
I had had anesthesia once before and it messed me up.
我以前接受过一次麻醉,这让我很困惑。
I could not function for a while afterwards.
之后我有一段时间无法工作。
And I said a lot of things that…
而且我说了很多话……
I was really worried that I was going to start, I don’t know, dropping some bombs and I wouldn’t even know.
我真的很担心我会开始,我不知道,扔一些炸弹,我什至不知道。
I wouldn’t remember.
我不记得了。
So I was like, “Please God, don’t let that happen, and please let me be there enough to do this to my mom.”
所以我想,“上帝啊,请不要让这种事发生,请让我有足够的时间对我的妈妈做这件事。”
7:09:54 And so she walked in after surgery.
就这样,她在手术后走进了医院。
It was the first time they had been able to see me after surgery, and she just looked at me.
这是手术后他们第一次见到我,她只是看着我。
She said, “Hi, how are you?
她说:“嗨,你好吗?
How are you doing?
你好吗?
How do you feel?” And I looked at her and this very, I think the anesthesia helped, very groggy, sort of confused look on my face.
你感觉如何?”我看着她,我觉得麻醉很有帮助,我脸上的表情非常昏昏沉沉,有点困惑。
It’s like, “Who are you?” And she just started looking around the room at the surgeons, at the doctors like, “What did you do to my son?
就像“你是谁?”她开始环顾房间,看着外科医生,看着医生,“你们对我儿子做了什么?
You need to fix this right now.” Tears started streaming.
你现在需要解决这个问题。”眼泪开始流。
I saw how much she was freaking out.
我看到她有多惊慌。
I was like, “I can’t let this go on.” And so I was like, “Mom, mom, I’m fine.
我当时想,“我不能让这种情况继续下去。”于是我就说:“妈妈,妈妈,我很好。
It’s all right.” And still, she was not happy about it.
没关系。”尽管如此,她对此并不高兴。
She still says she’s going to get me back someday, but I mean, I don’t know.
她仍然说有一天她会让我回来,但我的意思是,我不知道。
I don’t know what that’s going to look like.
我不知道那会是什么样子。
It’s a lifelong battle, man.
这是一场终生的战斗,伙计。
Yeah, but it was good.
是的,但那很好。
In some sense it was a demonstration that you still got…
从某种意义上说,这证明了你仍然拥有……
7:10:47 Still had a sense of humor.
还是有幽默感的。
That’s all I wanted it to be.
这就是我想要的。
7:10:52 That’s all I wanted it to be.
这就是我想要的。
And I knew that doing something super mean to her like that would show her.
我知道做一些对她来说非常刻薄的事情会让她明白。
To show that you’re still there, that you love her.
为了表明你还在那里,你爱她。
Yeah, exactly.
是的,完全正确。
7:11:01 Exactly.
正是如此。
It’s a dark way to do it, but I love it.
这是一种黑暗的做法,但我喜欢它。
Yeah.
是的。
What was the first time you were able to feel that you can use the Neuralink device to affect the world around you?
您第一次感受到可以使用 Neuralink 设备影响周围的世界是什么时候?
The first little taste I got of it was actually not too long after surgery.
我第一次尝到它的味道实际上是在手术后不久。
7:11:17 Some of the Neuralink team had brought in a little iPad, a little tablet screen, and they had put up eight different channels that were recording some of my neuron spikes and they put it in front of me.
Neuralink 团队的一些人带来了一个小 iPad、一个小平板电脑屏幕,他们设置了八个不同的通道来记录我的一些神经元尖峰,并将其放在我面前。
They’re like, “This is real time your brain firing.” I was like, “That’s super cool.” My first thought was, “I mean, if they’re firing now, let’s see if I can affect them in some way.”
他们就像是,“这是你大脑的实时放电。”我当时想,“这太酷了。”我的第一个想法是,“我的意思是,如果他们现在开火,让我们看看我是否能以某种方式影响他们。”
7:11:51 So I started trying to wiggle my fingers and I just started scanning through the channels, and one of the things I was doing was moving my index finger up and down, and I just saw this yellow spike on top row, third box over or something.
所以我开始尝试摆动我的手指,我开始扫描通道,我正在做的一件事就是上下移动我的食指,我刚刚看到顶行有一个黄色的尖峰,第三个盒子上方什么的。
I saw this yellow spike every time I did it, and I was like, “Oh, that’s cool.” And everyone around me was just like, “What are you seeing?” I was like, “Look at this one.
每次我这样做时,我都会看到这个黄色的尖刺,我就想,“哦,那太酷了。”我周围的每个人都说:“你看到了什么?”我当时想,“看看这个。
Look at this top row, third box over this yellow spike.
看看这个黄色尖峰上方的顶行第三个框。
That’s me right there, there, there.” And everyone was freaking out.
那就是我,就在那里,那里,那里。”每个人都吓坏了。
They started clapping.
他们开始鼓掌。
I was like, “That’s super unnecessary.” This is what’s supposed to happen, right?
我当时想,“这完全没有必要。”这是应该发生的事情,对吧?
So you’re imagining yourself moving each individual finger one at a time, and then seeing that you can notice something.
所以你想象自己一次移动一根手指,然后发现你能注意到一些东西。
7:12:29 And then when you did the index finger, you’re like, “Oh, cool.”
然后当你做食指时,你会说,“哦,酷。”
Yeah, I was wiggling all of my fingers to see if anything would happen.
是的,我扭动着所有的手指,看看是否会发生什么。
7:12:39 There was a lot of other things going on, but that big yellow spike was the one that stood out to me.
还有很多其他事情正在发生,但那个黄色的大尖刺对我来说是最引人注目的。
I’m sure that if I would’ve stared at it long enough, I could have mapped out maybe a hundred different things.
我确信,如果我盯着它看的时间足够长,我可能会绘制出一百种不同的东西。
But the big yellow spike was the one that I noticed.
但我注意到的是那个黄色的大尖刺。
Maybe you could speak to what it’s like to wiggle your fingers, to imagine the cognitive effort required to wiggle your index finger, for example.
例如,也许你可以谈论一下摆动手指的感觉,想象一下摆动食指所需的认知努力。
7:13:00 How easy is that to do?
这有多容易做到?
Pretty easy for me.
对我来说很容易。
7:13:13 It’s something that at the very beginning, after my accident, they told me to try and move my body as much as possible.
从一开始,在我发生事故后,他们就告诉我要尽可能多地移动我的身体。
Even if you can’t, just keep trying because that’s going to create new neural pathways or pathways in my spinal cord to reconnect these things to hopefully regain some movement someday.
即使你做不到,也要继续尝试,因为这将在我的脊髓中创建新的神经通路或通路来重新连接这些东西,希望有一天能重新获得一些运动能力。
That’s fascinating.
这很有趣。
Yeah, I know.
是的,我知道。
7:13:40 It’s bizarre.
这很奇怪。
That’s part of the recovery process is to keep trying to move your body.
恢复过程的一部分就是不断尝试移动你的身体。
Yep.
是的。
7:13:46 Every day as much as you can.
每天尽可能多。
And the nervous system does its thing.
神经系统发挥其作用。
7:13:49 It starts reconnecting.
它开始重新连接。
It’ll start reconnecting for some people, some people it never works.
对于某些人来说,它会开始重新连接,但对于某些人来说,它永远不会起作用。
7:13:52 Some people they’ll do it.
有些人他们会这么做。
For me, I got some bicep control back, and that’s about it.
对我来说,我恢复了一些二头肌控制力,仅此而已。
If I try enough, I can wiggle some of my fingers, not on command.
如果我尝试得足够多,我就可以摆动我的一些手指,而不是按照命令。
It’s more like if I try to move, say my right pinky, and I just keep trying to move it, after a few seconds it’ll wiggle.
更像是如果我尝试移动,比如说我的右手小指,我只是继续尝试移动它,几秒钟后它就会摆动。
So I know there’s stuff there.
所以我知道那里有东西。
I know, and that happens with a few different of my fingers and stuff.
我知道,这种情况发生在我的几个不同的手指和其他东西上。
But yeah, that’s what they tell you to do.
但是,是的,这就是他们告诉你要做的。
One of the people at the time when I was in the hospital came in and told me for one guy who had recovered most of his control, what he thought about every day was actually walking, like the act of walking just over and over again.
当我在医院的时候,一个人进来告诉我,对于一个已经恢复了大部分控制的人来说,他每天想到的实际上是行走,就像一遍又一遍地行走的行为。
So I tried that for years.
所以我尝试了很多年。
I tried just imagining walking, which is, it’s hard.
我试着想象走路,这很困难。
It’s hard to imagine all of the steps that go into, well, taking a step.
很难想象迈出一步需要经历的所有步骤。
All of the things that have to move, all of the activations that have to happen along your leg in order for one step to occur.
为了迈出一步,所有必须移动的东西,所有必须沿着你的腿发生的激活。
But you’re not just imagining, you’re doing it, right?
但你不只是想象,你正在做,对吧?
I’m trying.
我正在努力。
7:15:12 Yeah.
是的。
So it’s imagining over again what I had to do to take a step, because it’s not something any of us think about.
所以它再次想象我必须做什么才能迈出一步,因为这不是我们任何人都会想到的事情。
We just, you want to walk and you take a step.
我们只是,你想走,你就迈出一步。
You don’t think about all of the different things that are going on in your body.
您不会考虑体内正在发生的所有不同事情。
So I had to recreate that in my head as much as I could, and then I practice it over, and over, and over again.
所以我必须尽可能地在脑海中重现这一点,然后一遍又一遍地练习。
So it’s not like a third person perspective, it’s a first person perspective.
所以这不像第三人称视角,而是第一人称视角。
7:15:37 It’s not like you’re imagining yourself walking.
这不像你想象自己在走路。
You’re literally doing everything, all the same stuff as if you’re walking.
你实际上正在做所有的事情,就像你在走路一样。
Yeah, which was hard.
是的,这很难。
7:15:49 It was hard at the beginning.
一开始很困难。
Frustrating hard, or actually cognitively hard, which way?
令人沮丧困难,或者实际上认知困难,哪种方式?
It was both.
两者都是。
7:15:57 There’s a scene in one of the Kill Bill movies, actually, oddly enough, where she is paralyzed, I don’t know, from a drug that was in her system.
事实上,在《杀死比尔》电影中,有一个场景,很奇怪,我不知道,她因为体内的一种药物而瘫痪了。
And then she finds some way to get into the back of a truck or something, and she stares at her toe and she says, “Move,” like move your big toe.
然后她找到某种方法进入卡车或其他东西的后面,她盯着自己的脚趾说,“移动”,就像移动你的大脚趾一样。
And after a few seconds on screen, she does it.
屏幕上几秒钟后,她就这么做了。
And she did that with every one of her body parts until she can move again.
她对身体的每一个部位都这样做,直到她能再次活动为止。
I did that for years, just stared at my body and said, “Move your index finger, move your big toe.” Sometimes vocalizing it out loud, sometimes just thinking it.
我这样做了很多年,只是盯着我的身体说:“移动你的食指,移动你的大脚趾。”有时大声说出,有时只是思考。
I tried every different way to do this to try to get some movement back.
我尝试了各种不同的方法来做到这一点,试图恢复一些运动。
And it’s hard because it actually is taxing, physically taxing on my body, which is something I would’ve never expected.
这很难,因为它实际上对我的身体造成了负担,这是我从未预料到的。
7:16:58 It’s not like I’m moving, but it feels like there’s a buildup of, the only way I can describe it is there are signals that aren’t getting through from my brain down, because there’s that gap in my spinal cord, so brain down, and then from my hand back up to the brain.
我并没有在移动,但感觉好像有一种积聚,我能描述它的唯一方式是,信号没有从我的大脑向下传递,因为我的脊髓中有一个间隙,所以大脑向下,然后从我的手回到大脑。
And so it feels like those signals get stuck in whatever body part that I’m trying to move, and they just build up, and build up, and build up until they burst.
所以感觉这些信号被困在我试图移动的任何身体部位,它们只会积聚、积聚、积聚,直到爆发。
And then once they burst, I get this really weird sensation of everything dissipating back out to level, and then I do it again.
然后一旦它们爆炸,我就会有一种非常奇怪的感觉,一切都消散回原来的水平,然后我会再做一次。
7:17:42 It’s also just a fatigue thing, like a muscle fatigue, but without actually moving your muscles.
这也只是一种疲劳,就像肌肉疲劳一样,但实际上并没有移动你的肌肉。
It’s very, very bizarre.
这非常非常奇怪。
And then if you try to stare at a body part or think about a body part and move for two, three, four, sometimes eight hours, it’s very taxing on your mind.
然后,如果你试图盯着身体的某个部位或思考身体的某个部位,并移动两个、三个、四个,有时甚至八个小时,这对你的大脑来说是非常沉重的负担。
It takes a lot of focus.
这需要高度集中注意力。
It was a lot easier at the beginning because I wasn’t able to control a TV in my room or anything.
一开始要容易得多,因为我无法控制房间里的电视或任何东西。
I wasn’t able to control any of my environment.
我无法控制我的任何环境。
So for the first few years, a lot of what I was doing was staring at walls.
所以在最初的几年里,我所做的很多事情都是盯着墙壁。
And so, obviously I did a lot of thinking and I tried to move a lot just over, and over, and over again.
所以,显然我做了很多思考,并且尝试着一遍又一遍地移动。
So you never gave up hope there?
所以你从未放弃过希望?
No.
不。
Just training hard [inaudible 07:18:38].
只是努力训练 [听不清 07:18:38]。
Yeah.
是的。
7:18:37 And I still do it.
我仍然这样做。
I do it subconsciously, and I think that that helped a lot with things with Neuralink, honestly.
我是下意识地这样做的,老实说,我认为这对 Neuralink 的工作有很大帮助。
It’s something that I talked about the other day at the All Hands that I did at Neuralink’s Austin facility.
前几天我在 Neuralink 奥斯汀工厂举行的全体会议上谈到了这一点。
Welcome to Austin, by the way.
顺便说一句,欢迎来到奥斯汀。
Yeah.
是的。
7:18:54 Hey, thanks man.
嘿,谢谢伙计。
I went to school-
我去学校了-
Nice hat.
漂亮的帽子。
…
……
7:18:57 Hey, thanks.
嘿,谢谢。
Thanks, man.
谢谢,伙计。
The Gigafactory was super cool.
超级工厂超级酷。
I went to school at [inaudible 07:19:01], so I’ve been around before.
我在 [听不清 07:19:01] 去学校,所以我以前来过。
So you should be saying welcome to me.
所以你应该对我说欢迎。
7:19:02 Welcome to Texas, Lex.
欢迎来到德克萨斯州,莱克斯。
Yeah.
是的。
I get you.
我明白你了。
But yeah, I was talking about how a lot of what they’ve had me do, especially at the beginning, well, I still do it now, is body mapping.
但是,是的,我说的是他们让我做的很多事情,尤其是在一开始,嗯,我现在仍然在做,是身体测绘。
7:19:08 So there will be a visualization of a hand or an arm on the screen, and I have to do that motion, and that’s how they train the algorithm to understand what I’m trying to do.
因此,屏幕上会出现一只手或手臂的可视化,我必须做这个动作,这就是他们训练算法来理解我想要做什么的方式。
And so it made things very seamless for me I think.
所以我认为这让我的事情变得非常顺利。
That’s really, really cool.
这真的非常非常酷。
7:19:38 So it’s amazing to know.
所以知道这一点真是太神奇了。
I’ve learned a lot about the body mapping procedure with the interface and everything like that.
我学到了很多关于身体映射程序和界面以及类似的东西。
It’s cool to know that you’ve been essentially training to be world-class at that task.
很高兴知道您基本上一直在接受训练,以便在这项任务上达到世界一流水平。
Yeah.
是的。
7:19:52 Yeah.
是的。
I don’t know if other quadriplegics, other paralyzed people give up.
我不知道其他四肢瘫痪、其他瘫痪的人是否放弃了。
I hope they don’t.
我希望他们不会。
I hope they keep trying, because I’ve heard other paralyzed people say, “Don’t ever stop.” They tell you two years, but you just never know.
我希望他们继续尝试,因为我听到其他瘫痪者说:“永远不要停止。”他们告诉你两年,但你永远不知道。
The human body’s capable of amazing things.
人体有能力做出令人惊奇的事情。
So I’ve heard other people say, “Don’t give up.” I think one girl had spoken to me through some family members and said that she had been paralyzed for 18 years, and she’d been trying to wiggle her index finger for all that time, and she finally got it back 18 years later.
所以我听到其他人说:“不要放弃。”我记得有一个女孩通过家人跟我说,她瘫痪了18年,一直在努力摆动食指,18年后终于恢复了。
So I know that it’s possible, and I’ll never give up doing it.
所以我知道这是可能的,而且我永远不会放弃这样做。
I do it when I’m lying down watching TV.
当我躺着看电视时我会这样做。
I’ll find myself doing it just almost on its own.
我会发现自己几乎可以自己做这件事。
It’s just something I’ve gotten so used to doing that I don’t know.
这只是我已经习惯做但我不知道的事情。
I don’t think I’ll ever stop.
我想我永远不会停止。
That’s really awesome to hear.
听到这真是太棒了。
7:20:54 I think it’s one of those things that can really pay off in the long term.
我认为从长远来看,这是真正能带来回报的事情之一。
It is training.
这是训练。
You’re not visibly seeing the results of that training at the moment, but there’s that Olympic level nervous system getting ready for something.
目前你还看不到训练的结果,但奥运会级别的神经系统正在为某些事情做好准备。
Which honestly was something that I think Neuralink gave me that I can’t thank them enough for.
老实说,我认为 Neuralink 给了我一些东西,对此我感激不尽。
7:21:08 I can’t show my appreciation for it enough, was being able to visually see that what I’m doing is actually having some effect.
我无法表达我对它的感激之情,能够直观地看到我正在做的事情实际上产生了一些效果。
It’s a huge part of the reason why I know now that I’m going to keep doing it forever.
这是我现在知道我将永远继续这样做的一个重要原因。
Because before Neuralink, I was doing it every day and I was just assuming that things were happening.
因为在 Neuralink 之前,我每天都这样做,而且我只是假设事情正在发生。
It’s not like I knew.
这不像我所知道的。
I wasn’t getting back any mobility or sensation or anything.
我没有恢复任何活动能力、感觉或任何东西。
So I could have been running up against a brick wall for all I knew.
所以据我所知,我可能会碰壁。
And with Neuralink, I get to see all the signals happening real time, and I get to see that what I’m doing can actually be mapped.
通过 Neuralink,我可以看到所有实时发生的信号,并且我可以看到我正在做的事情实际上可以被映射。
When we started doing click calibrations and stuff, when I go to click my index finger for a left click, that it actually recognizes that.
当我们开始进行点击校准之类的事情时,当我点击食指进行左键点击时,它实际上可以识别这一点。
It changed how I think about what’s possible with retraining my body to move.
它改变了我对重新训练身体运动的可能性的看法。
And so yeah, I’ll never give up now.
所以是的,我现在永远不会放弃。
And also just the signal that there’s still a powerhouse of a brain there that’s like, and as the technology develops, that brain is, I mean, that’s the most important thing about the human body is the brain, and it can do a lot of the control.
还有一个信号表明,那里仍然有一个强大的大脑,随着技术的发展,大脑,我的意思是,人体最重要的是大脑,它可以做很多控制。
7:22:28 So what did it feel like when you first could wiggle the index finger and saw the environment respond?
那么,当您第一次摆动食指并看到环境做出反应时,感觉如何?
That little thing, whatever [inaudible 07:22:49] just being way too dramatic according to you?
那件小事,无论如何 [听不清 07:22:49] 在你看来太戏剧化了?
Yeah, it was very cool.
是的,这非常酷。
7:22:51 I mean, it was cool, but I keep telling this to people.
我的意思是,这很酷,但我一直向人们讲述这一点。
It made sense to me.
这对我来说很有意义。
It made sense that there are signals still happening in my brain, and that as long as you had something near it that could measure those, that could record those, then you should be able to visualize it in some way.
这是有道理的,我的大脑中仍在发生信号,只要你附近有东西可以测量这些信号,可以记录这些信号,那么你应该能够以某种方式将其可视化。
See it happen.
看到它发生。
And so that was not very surprising to me.
所以这对我来说并不奇怪。
I was just like, “Oh, cool.
我只是想,“哦,酷。
We found one, we found something that works.”
我们找到了一个,我们找到了有用的东西。”
7:23:23 It was cool to see that their technology worked and that everything that they had worked so hard for was going to pay off.
很高兴看到他们的技术发挥了作用,并且他们辛勤工作的一切都将得到回报。
But I hadn’t moved a cursor or anything at that point.
但那时我还没有移动光标或任何东西。
I hadn’t interacted with a computer or anything at that point.
那时我还没有与电脑或任何东西互动。
So it just made sense.
所以这是有道理的。
It was cool.
很酷。
I didn’t really know much about BCI at that point either, so I didn’t know what sort of step this was actually making.
那时我对 BCI 也不太了解,所以我不知道这实际上迈出了什么样的一步。
I didn’t know if this was a huge deal, or if this was just like, “Okay, this is, it’s cool that we got this far, but we’re actually hoping for something much better down the road.” It’s like, “Okay.” I just thought that they knew that it turned on.
我不知道这是否是一件大事,或者这是否只是像,“好吧,这就是,我们走到这一步很酷,但我们实际上希望未来能有更好的事情。”就像,“好吧。”我只是以为他们知道它打开了。
So I was like, “Cool, this is cool.”
所以我就想,“酷,这太酷了。”
Well, did you read up on the specs of the hardware you get installed, the number of threads, all this kind of stuff.
好吧,您是否仔细阅读了所安装硬件的规格、线程数量以及所有此类内容。
Yeah, I knew all of that, but it’s all Greek to me.
是的,我知道所有这些,但对我来说这都是希腊语。
7:24:16 I was like, “Okay, 64 threads, 16 electrodes, 1,024 channels.
我当时想,“好吧,64 个线程,16 个电极,1,024 个通道。
Okay, that math checks out.”
好吧,数学检验完毕。”
Sounds right.
听起来不错。
Yeah.
是的。
When was the first time you were able to move a mouse cursor?
您第一次能够移动鼠标光标是什么时候?
I know it must have been within the first maybe week, a week or two weeks that I was able to first move the cursor.
我知道一定是在我能够第一次移动光标的第一周、一周或两周内。
7:24:34 And again, it kind of made sense to me.
再说一遍,这对我来说有点道理。
It didn’t seem like that big of a deal.
这看起来没什么大不了的。
It was like, okay, well, how do I explain this?
就像,好吧,好吧,我该怎么解释呢?
When everyone around you starts clapping for something that you’ve done, it’s easy to say, “Okay, I did something cool.”
当你周围的每个人都开始为你所做的事情鼓掌时,你很容易说:“好吧,我做了一些很酷的事情。”
7:25:04 That was impressive in some way.
这在某种程度上令人印象深刻。
What exactly that meant, what it was hadn’t really set in for me.
这到底意味着什么,我并没有真正理解它是什么。
So again, I knew that me trying to move a body part and then that being mapped in some sort of machine learning algorithm to be able to identify my brain signals and then take that and give me cursor control, that all kind of made sense to me.
再说一遍,我知道我试图移动身体的某个部位,然后将其映射到某种机器学习算法中,以便能够识别我的大脑信号,然后利用它并给我光标控制,这对我来说都是有意义的。
I don’t know all the ins and outs of it, but I was like, “There are still signals in my brain firing.
我不知道它的所有来龙去脉,但我当时想,“我的大脑中仍然有信号在放电。
They just can’t get through because there’s a gap in my spinal cord, and so they can’t get all the way down and back up, but they’re still there.” So when I moved the cursor for the first time, I was like, “That’s cool, but I expected that that should happen.” It made sense to me.
他们就是无法通过,因为我的脊髓中有一个缺口,所以他们无法一路下降和返回,但他们仍然在那里。”因此,当我第一次移动光标时,我想,“这很酷,但我预计会发生这种情况。”这对我来说很有意义。
When I moved the cursor for the first time with just my mind, without physically trying to move.
当我第一次仅用意念移动光标时,没有身体尝试移动。
So I guess I can get into that just a little bit.
所以我想我可以稍微讨论一下。
The difference between attempted movement, and imagine movement.
尝试运动和想象运动之间的区别。
Yeah, that’s a fascinating difference [inaudible 07:26:18] from one to the other.
是的,这是一个令人着迷的差异 [听不清 07:26:18]。
Yeah, yeah, yeah.
是啊,是啊,是啊。
7:26:19 So attempted movement is me physically trying to attempt to move, say my hand.
所以尝试移动是指我在身体上试图移动,比如我的手。
I try to attempt to move my hand to the right, to the left, forward and back.
我尝试将手向右、向左、向前和向后移动。
And that’s all attempted.
这都是尝试过的。
Attempt to lift my finger up and down, attempt to kick or something.
尝试上下抬起手指,尝试踢腿什么的。
I’m physically trying to do all of those things, even if you can’t see it.
我正在努力做所有这些事情,即使你看不到。
This would be me attempting to shrug my shoulders or something.
这就是我试图耸肩什么的。
That’s all attempted movement.
这就是所有尝试的运动。
That’s what I was doing for the first couple of weeks when they were going to give me cursor control.
这就是我在最初几周所做的事情,当时他们要给我光标控制权。
When I was doing body mapping, it was attempt to do this, attempt to do that.
当我做身体测绘时,就是尝试做这个,尝试做那个。
When Nir was telling me to imagine doing it, it kind of made sense to me, but it’s not something that people practice.
当尼尔告诉我想象这样做时,这对我来说有点道理,但这不是人们实践的事情。
If you started school as a child and they said, “Okay, write your name with this pencil,” and so you do that.
如果你小时候开始上学,他们说:“好吧,用这支铅笔写下你的名字”,所以你就这么做了。
Like, “Okay, now imagine writing your name with that pencil.”
就像,“好吧,现在想象一下用那支铅笔写下你的名字。”
7:27:33 Kids would think, “Uh, I guess that kind of makes sense,” and they would do it.
孩子们会想,“呃,我想这是有道理的”,然后他们就会这么做。
But that’s not something we’re taught, it’s all how to do things physically.
但这不是我们被教导的东西,而是如何用身体做事。
We think about thought experiments and things, but that’s not a physical action of doing things.
我们思考思想实验和事物,但这不是做事的身体动作。
It’s more what you would do in certain situations.
这更多的是你在某些情况下会做的事情。
So imagine movement, it never really connected with me.
所以想象一下运动,它从未真正与我联系在一起。
I guess you could maybe describe it as a professional athlete swinging a baseball bat or swinging a golf club.
我想你可以将其描述为挥动棒球棒或挥动高尔夫球杆的职业运动员。
Imagine what you’re supposed to do.
想象一下你应该做什么。
But then you go right to that and physically do it.
但随后你就直接去做,并亲自去做。
Then you get a bat in your hand, and then you do what you’ve been imagining.
然后你手里拿着一根球棒,然后你就可以做你一直在想象的事情了。
7:28:15 And so I don’t have that connection.
所以我没有这种联系。
So telling me to imagine something versus attempting it, there wasn’t a lot that I could do there mentally.
所以告诉我想象某件事而不是尝试它,我在心理上能做的事情并不多。
I just kind of had to accept what was going on and try.
我只是不得不接受正在发生的事情并尝试。
But the attempted moving thing, it all made sense to me.
但尝试移动的事情,这对我来说都是有意义的。
If I try to move, then there’s a signal being sent in my brain, and as long as they can pick that up, then they should be able to map it to what I’m trying to do.
如果我尝试移动,那么我的大脑中就会发送一个信号,只要他们能够接收到该信号,那么他们应该能够将其映射到我想要做的事情。
And so when I first moved the cursor like that, it was just like, “Yes, this should happen.
所以当我第一次像这样移动光标时,就像是,“是的,这应该发生。
I’m not surprised by that.”
我对此并不感到惊讶。”
But can you clarify, is there supposed to be a difference between imagine movement and attempted movement?
但你能否澄清一下,想象运动和尝试运动之间是否应该有区别?
Yeah, just that in imagine movement, you’re not attempting to move at all.
是的,只是在想象运动时,你根本没有试图移动。
7:28:55 So it’s-
所以这是——
You’re visualizing what you’re doing.
你正在想象你正在做的事情。
…
……
7:29:01 Visualizing.
可视化。
…
……
7:29:03 And then theoretically, is that supposed to be a different part of the brain that lights up in those two different situations?
从理论上讲,这是否应该是大脑的不同部分在这两种不同的情况下被点亮?
Yeah, not necessarily.
是的,不一定。
7:29:09 I think all these signals can still be represented in motor cortex, but the difference I think, has to do with the naturalness of imagining something versus-
我认为所有这些信号仍然可以在运动皮层中表示,但我认为差异与想象某些事物的自然性与-
Got it.
明白了。
…
……
7:29:18 attempting it.
尝试它。
The fatigue of that over time.
随着时间的推移,会产生疲劳感。
And by the way, on the mic is Bliss.
顺便说一下,麦克风里的是布利斯。
7:29:20 So this is just different ways to prompt you to kind of get to the thing that you arrived at.
所以这只是提示你达到你所达到的目标的不同方式。
Yeah, yeah.
是啊是啊。
Attempted movement does sound like the right thing.
尝试移动听起来确实是正确的事情。
7:29:31 Try.
尝试。
Yeah.
是的。
7:29:35 I mean, it makes sense to me.
我的意思是,这对我来说很有意义。
Because imagine, for me, I would start visualizing, in my mind, visualizing.
因为想象一下,对我来说,我会开始在脑海中想象、想象。
7:29:37 Attempted I would actually start trying to…
我尝试过实际上会开始尝试……
I did combat sports my whole life, like wrestling.
我一生都从事格斗运动,比如摔跤。
When I’m imagining a move, see, I’m moving my muscle.
当我想象一个动作时,看,我正在移动我的肌肉。
Exactly.
确切地。
There is a bit of an activation almost versus visualizing yourself, like a picture doing it.
与想象自己相比,有一点激活,就像一张图片在做的那样。
Yeah.
是的。
7:30:01 It’s something that I feel like naturally anyone would do.
我觉得这是任何人自然都会做的事情。
If you try to tell someone to imagine doing something, they might close their eyes and then start physically doing it, but it just-
如果你试图告诉某人想象做某事,他们可能会闭上眼睛,然后开始实际做,但这只是 -
Just didn’t click.
只是没有点击。
…
……
7:30:14 Yeah, it’s hard.
是的,这很难。
It was very hard at the beginning.
刚开始的时候非常困难。
But attempted worked.
但尝试奏效了。
Attempted worked.
尝试成功了。
7:30:20 It worked just like it should.
它就像它应该的那样工作。
Worked like a charm.
工作起来就像一个魅力。
Remember there was one Tuesday we were messing around and I think, I forget what swear word you used, but there’s a swear word that came out of your mouth when you figured out you could just do the direct cursor control.
记得有一个星期二我们在一起闲逛,我想,我忘记了你用了什么脏话,但是当你发现你可以直接进行光标控制时,有一个脏话从你嘴里出来。
Yeah, it blew my mind, no pun intended.
是的,这让我大吃一惊,没有双关语的意思。
7:30:35 Blew my mind when I first moved the cursor just with my thoughts and not attempting to move.
当我第一次只是用我的想法移动光标而不是尝试移动时,我大吃一惊。
It’s something that I found over the couple of weeks building up to that, that as I get better cursor controls, the model gets better, then it gets easier for me to…
这是我在几周的时间里发现的,随着我获得更好的光标控制,模型变得更好,然后我就更容易......
I don’t have to attempt as much to move it.
我不必费尽心思去移动它。
And part of that is something that I’d even talked with them about when I was watching the signals of my brain one day.
其中一部分是我有一天在观察我的大脑信号时与他们讨论过的事情。
I was watching when I attempted to move to the right and I watched the screen as I saw the spikes.
当我试图向右移动时,我正在观察,当我看到尖峰时,我看着屏幕。
I was seeing the spike, the signal was being sent before I was actually attempting to move.
我看到了尖峰,在我真正尝试移动之前信号就已发送。
I imagine just because when you go to say, move your hand or any body part, that signal gets sent before you’re actually moving, has to make it all the way down and back up before you actually do any sort of movement.
我想只是因为当你说,移动你的手或任何身体部位时,该信号会在你实际移动之前发送,必须在你实际进行任何类型的移动之前一直向下和返回。
7:31:51 So there’s a delay there.
所以那里有延迟。
And I noticed that there was something going on in my brain before I was actually attempting to move that my brain was anticipating what I wanted to do, and that all started sort of, I don’t know, percolating in my brain.
我注意到,在我真正尝试移动之前,我的大脑中正在发生一些事情,我的大脑正在预测我想做的事情,而这一切都开始渗透到我的大脑中,我不知道。
It was just there always in the back like, “That’s so weird that it could do that.
它总是在后面,就像,“这太奇怪了,它能做到这一点。
It kind of makes sense, but I wonder what that means as far as using the Neuralink.”
这有点道理,但我想知道这对于使用 Neuralink 意味着什么。”
7:32:29 And then as I was playing around with the attempted movement and playing around with the cursor, and I saw that as the cursor control got better, that it was anticipating my movements and what I wanted it to do, like cursor movements, what I wanted it to do a bit better and a bit better.
然后,当我尝试尝试移动并玩弄光标时,我发现随着光标控制变得更好,它正在预测我的动作以及我想要它做什么,就像光标移动一样,我希望它做得越来越好。
And then one day I just randomly, as I was playing Webgrid, I looked at a target before I had started attempting to move, I was just trying to get over, train my eyes to start looking ahead, like, “Okay, this is the target I’m on, but if I look over here to this target, I know I can maybe be a bit quicker getting there.”
然后有一天,当我玩 Webgrid 时,我在开始尝试移动之前看着一个目标,我只是想克服,训练我的眼睛开始向前看,就像,“好吧,这就是我正在瞄准的目标,但如果我看向这个目标,我知道我也许可以更快一点到达那里。”
7:33:12 And I looked over and the cursor just shot over.
我看过去,光标就飞了过来。
It was wild.
很狂野。
I had to take a step back.
我不得不退后一步。
I was like, “This should not be happening.” All day I was just smiling.
我当时想,“这不应该发生。”一整天我只是微笑。
I was so giddy.
我太头晕了。
I was like, “Guys, do you know that this works?
我当时想,“伙计们,你们知道这有效吗?
I can just think it and it happens.” Which they’d all been saying this entire time like, “I can’t believe you’re doing all this with your mind.” I’m like, “Yeah, but is it really with my mind.
我只要想一想,它就会发生。”他们一直在说,“我不敢相信你用你的头脑做这一切。”我想,“是的,但这真的是我的想法吗?
I’m attempting to move and it’s just picking that up so it doesn’t feel like it’s with my mind.” But when I moved it for the first time like that, it was, oh man.
我试图移动,但它只是捡起了它,所以感觉不像是我的想法。”但当我第一次像这样移动它时,天哪。
It made me think that this technology, that what I’m doing is actually way, way more impressive than I ever thought.
这让我觉得这项技术,我正在做的事情实际上比我想象的更令人印象深刻。
It was way cooler than I ever thought, and it just opened up a whole new world of possibilities of what could possibly happen with this technology and what I might be able to be capable of with it.
它比我想象的要酷得多,而且它开启了一个全新的世界,充满了这项技术可能发生的事情以及我能够用它实现的能力。
Because you had felt for the first time like this was digital telepathy.
因为你第一次感觉到这是数字心灵感应。
7:34:08 You’re controlling a digital device with your mind.
您正在用意念控制数字设备。
Yep.
是的。
I mean, that’s a real moment of discovery.
我的意思是,那是一个真正的发现时刻。
7:34:16 That’s really cool.
这真的很酷。
You’ve discovered something.
你发现了一些东西。
I’ve seen scientists talk about a big aha moment, like Nobel Prize winning.
我见过科学家谈论重大的顿悟时刻,比如获得诺贝尔奖。
They’ll have this like, “Holy crap.” Like, “Whoa.”
他们会说“天啊”。就像,“哇”。
That’s what it felt like.
这就是感觉。
7:34:31 I felt like I had discovered something, but for me, maybe not necessarily for the world-at-large or this field-at-large, it just felt like an aha moment for me.
我觉得我发现了一些东西,但对我来说,也许不一定对整个世界或这个领域来说,这对我来说只是一个顿悟的时刻。
Like, “Oh, this works.” Obviously it works.
就像,“哦,这有效。”显然它有效。
And so that’s what I do all the time now.
这就是我现在一直在做的事情。
I kind of intermix the attempted movement and imagine movement.
我有点将尝试的运动和想象的运动混合在一起。
I do it all together because I’ve found that…
我一起做这一切,因为我发现……
7:35:00 I do it all together because I’ve found that there is some interplay with it that maximizes efficiency with the cursor.
我把这一切都放在一起,因为我发现它们之间有一些相互作用,可以最大限度地提高光标的效率。
So it’s not all one or the other.
所以这并不全是其中之一。
It’s not all just, I only use attempted or I only use imagined movements.
不全是这样,我只使用尝试的动作或者只使用想象的动作。
It’s more I use them in parallel and I can do one or the other.
我更多的是并行使用它们,我可以选择其中之一。
I can just completely think about whatever I’m doing, but I don’t know, I like to play around with it.
我可以完全思考我在做什么,但我不知道,我喜欢玩它。
I also like to just experiment with these things.
我也喜欢尝试这些东西。
Every now and again, I’ll get this idea in my head, I wonder if this works and I’ll just start doing it, and then afterwards I’ll tell them, “By the way, I wasn’t doing that like you guys wanted me to.
时不时地,我的脑海里就会出现这个想法,我想知道这是否有效,然后我就会开始这样做,然后我会告诉他们,“顺便说一句,我并没有像你们希望我那样做。
I thought of something and I wanted to try it and so I did.
我想到了一件事,我想尝试一下,所以我就这么做了。
It seems like it works, so maybe we should explore that a little bit.”
看起来它确实有效,所以也许我们应该对此进行一些探索。”
So I think that discovery’s not just for you, at least from my perspective.
所以我认为这个发现不仅仅适合你,至少从我的角度来看是这样。
7:35:51 That’s a discovery for everyone else who ever uses a Neuralink that this is possible.
对于所有使用过 Neuralink 的人来说,这都是一个发现:这是可能的。
I don’t think that’s an obvious thing that this is even possible.
我认为这是不可能的,这是显而易见的事情。
It’s like I was saying to Bliss earlier, it’s like the four-minute mile.
就像我之前对布利斯说的那样,这就像四分钟一英里。
People thought it was impossible to run a mile in four minutes and once the first person did it, then everyone just started doing it.
人们认为四分钟内跑完一英里是不可能的,一旦第一个人做到了,然后每个人都开始这样做。
So just to show that it’s possible, that paves the way to anyone can now do it.
所以只是为了表明这是可能的,这为现在任何人都可以做到这一点铺平了道路。
That’s the thing that’s actually possible.
这才是真正可能的事情。
You don’t need to do the attempted movement, you can just go direct.
你不需要做尝试的动作,你可以直接进行。
Yeah.
是的。
7:36:25 Yeah.
是的。
That’s crazy.
这太疯狂了。
It is crazy.
这太疯狂了。
7:36:27 It is crazy, yeah.
这太疯狂了,是的。
For people who don’t know, can you explain how the Link app works?
对于不知道的人,你能解释一下 Link 应用程序是如何工作的吗?
7:36:30 You have an amazing stream on the topic.
您对这个主题有精彩的报道。
Your first stream, I think, on X describing, the app.
我想,你的第一个直播是在 X 上描述该应用程序的。
Can you just describe how it works?
您能简单描述一下它是如何工作的吗?
Yeah, so it’s just an app that Neuralink created to help me interact with the computer.
是的,所以它只是 Neuralink 创建的一个应用程序,旨在帮助我与计算机交互。
7:36:43 So on the Link app there are a few different settings, and different modes, and things I can do on it.
因此,在 Link 应用程序上有一些不同的设置、不同的模式以及我可以在上面执行的操作。
So there’s the body mapping, which we kind of touched on.
这就是我们接触过的身体映射。
There’s a calibration.
有一个校准。
Calibration is how I actually get cursor control, so calibrating what’s going on in my brain to translate that into cursor control.
校准是我实际获得光标控制的方式,因此校准我大脑中发生的事情,将其转化为光标控制。
So it will pop out models.
所以它会弹出模型。
What they use, I think, is time.
我认为他们使用的是时间。
So it would be five minutes and calibration will give me so good of a model, and then if I’m in it for 10 minutes and 15 minutes, the models will progressively get better.
所以这需要 5 分钟,校准会给我一个很好的模型,然后如果我在其中呆 10 分钟和 15 分钟,模型会逐渐变得更好。
And so the longer I’m in it, generally, the better the models will get.
所以一般来说,我投入的时间越长,模型就会越好。
That’s really cool because you often refer to the models.
这真的很酷,因为你经常参考这些模型。
7:37:43 So the model’s the thing that’s constructed once you go through the calibration step.
因此,模型是在完成校准步骤后构建的。
Yeah.
是的。
And then you also talked about sometimes you’ll play a really difficult game like Snake just to see how good the model is.
然后您还谈到有时您会玩像贪吃蛇这样非常困难的游戏,只是为了看看模型有多好。
Yeah.
是的。
7:37:56 Yeah, so Snake is kind of like my litmus test for models.
是的,Snake 有点像我对模型的试金石。
If I can control a snake decently well then I know I have a pretty good model.
如果我能很好地控制蛇,那么我就知道我有一个非常好的模型。
So yeah, the Link app has all of those.
是的,Link 应用程序拥有所有这些。
It has Webgrid in it now.
现在它已经有了Webgrid。
It’s also how I connect to the computer just in general.
这也是我连接计算机的一般方式。
So they’ve given me a lot of voice controls with it at this point.
所以他们现在给了我很多语音控制功能。
So I can say, “Connect,” or, “Implant disconnect,” and as long as I have that charger handy, then I can connect to it.
所以我可以说“连接”或“植入物断开连接”,只要我手边有充电器,我就可以连接它。
So the charger is also how I connect to the Link app to connect to the computer.
所以充电器也是我连接Link应用程序连接电脑的方式。
I have to have the implant charger over my head when I want to connect, to have it wake up, because the implant’s in hibernation mode always when I’m not using it.
当我想要连接时,我必须将植入充电器放在头上,才能唤醒它,因为当我不使用它时,植入设备始终处于休眠模式。
I think there’s a setting to wake it up every so long, so we could set it to half an hour, or five hours, or something, if I just want it to wake up periodically.
我认为有一个设置可以每隔一段时间唤醒它,所以如果我只是想让它定期唤醒,我们可以将其设置为半小时,或五个小时,或其他时间。
7:38:56 So yeah, I’ll connect to the Link app and then go through all sorts of things, calibration for the day, maybe body mapping.
所以,是的,我将连接到 Link 应用程序,然后完成各种事情,当天的校准,也许是身体测绘。
I made them give me a little homework tab because I am very forgetful and I forget to do things a lot.
我让他们给了我一个小家庭作业标签,因为我很健忘,经常忘记做事。
So I have a lot of data collection things that they want me to do.
所以我有很多他们希望我做的数据收集工作。
Is the body mapping part of the data collection or is that also part of the calibration?
身体测绘是数据收集的一部分还是校准的一部分?
Yeah, it is.
是的,确实如此。
7:39:21 It’s something that they want me to do daily, which I’ve been slacking on because I’ve been doing so much media and traveling so much.
这是他们希望我每天做的事情,但我一直在懈怠,因为我做了太多的媒体工作和太多的旅行。
So I’ve been [inaudible 07:39:30]-
所以我一直[听不清 07:39:30]-
You’ve gotten super famous.
你变得超级有名了。
Yeah, I’ve been a terrible first candidate for how much I’ve been slacking on my homework.
是的,由于我在家庭作业上的懈怠,我在第一名候选人中表现很糟糕。
7:39:31 But yeah, it’s just something that they want me to do every day to track how well the Neuralink is performing over time and to have something to give, I imagine, to give to the FDA to create all sorts of fancy charts and stuff, and show like, hey, this is what the Neuralink…
但是,是的,这只是他们希望我每天做的事情,以跟踪 Neuralink 随着时间的推移表现如何,并提供一些东西,我想,给 FDA 创建各种奇特的图表和东西,并显示,嘿,这就是 Neuralink ......
This is how it’s performing day one, versus day 90, versus day 180, and things like that.
这就是它在第一天、第 90 天、第 180 天以及类似情况下的表现。
What’s the calibration step like?
校准步骤是什么样的?
7:40:02 Is it move left, move right?
是向左移动还是向右移动?
It’s a bubble game.
这是一个泡泡游戏。
7:40:06 So there will be yellow bubbles that pop up on the screen.
所以屏幕上会弹出黄色的气泡。
At first, it is open loop.
起初,它是开环的。
So open loop, this is something that I still don’t fully understand, the open loop and closed loop thing.
那么开环,这是我还没有完全理解的事情,开环和闭环的事情。
The me and Bliss talked for a long time about the difference between the two on the technical side.
我和Bliss讨论了很长时间两者在技术方面的区别。
Okay, yeah.
好吧,是的。
So it’d be great to hear your-
所以很高兴听到你的-
Okay, so open-
好吧,那么开放——
…
……
7:40:27 your side of the story.
你的故事。
Open loop is basically I have no control over the cursor.
开环基本上就是我无法控制光标。
7:40:29 The cursor will be moving on its own across the screen and I am following, by intention, the cursor to different bubbles.
光标将在屏幕上自行移动,我有意跟随光标到不同的气泡。
And then the algorithm is training off of what the signals it’s getting are as I’m doing this.
然后,当我这样做时,算法会根据收到的信号进行训练。
There are a couple of different ways that they’ve done it.
他们有几种不同的方法来做到这一点。
They call it center-out targets.
他们称之为中心向外目标。
So there will be a bubble in the middle and then eight bubbles around that, and the cursor will go from the middle to one side.
所以中间会有一个气泡,然后周围有八个气泡,光标将从中间移动到一侧。
So say, middle to left, back to middle, to up, to middle, up, right, and they’ll do that all the way around the circle.
所以说,从中间到左,从后到中间,到上,到中间,上,右,他们会绕着一圈这样做。
And I will follow that cursor the whole time, and then it will train off of my intentions, what it is expecting my intentions to be throughout the whole process.
我会一直跟随那个光标,然后它会根据我的意图进行训练,在整个过程中它期望我的意图是什么。
Can you actually speak to, when you say follow-
当你说跟随时,你真的能说话吗?
Yes.
是的。
…
……
7:41:25 you don’t mean with your eyes, you mean with your intentions?
你不是说用你的眼睛,你是说用你的意图?
Yeah, so generally for calibration, I’m doing attempted movements because I think it works better.
是的,所以一般来说,为了校准,我会尝试做一些动作,因为我认为这样效果更好。
7:41:28 I think the better models, as I progress through calibration, make it easier to use imagined movements.
我认为,随着我在校准过程中取得进展,更好的模型可以更轻松地使用想象的运动。
Wait.
等待。
7:41:45 Wait, wait, wait.
等等,等等,等等。
So calibrated on attempted movement will create a model that makes it really effective for you to then use the force.
因此,对尝试的运动进行校准将创建一个模型,使您能够真正有效地使用力量。
Yes.
是的。
7:41:55 I’ve tried doing calibration with imagined movement and it just doesn’t work as well for some reason.
我尝试过用想象的运动进行校准,但由于某种原因效果不佳。
So that was the center-out targets.
这就是中心向外的目标。
There’s also one where a random target will pop up on the screen and it’s the same.
还有一种是屏幕上会弹出一个随机目标,也是一样的。
I just move, I follow along wherever the cursor is, to that target all across the screen.
我只是移动,无论光标在哪里,我都会跟随屏幕上的目标。
I’ve tried those with imagined movement and for some reason the models just don’t, they don’t give as high level as quality when we get into closed loop.
我尝试过那些带有想象运动的模型,但出于某种原因,这些模型就是不能,当我们进入闭环时,它们无法提供高水平的质量。
I haven’t played around with it a ton, so maybe the different ways that we’re doing calibration now might make it a bit better.
我还没有经常使用它,所以也许我们现在进行校准的不同方法可能会让它变得更好一些。
But what I’ve found is there will be a point in calibration where I can use imagined movement.
但我发现在校准中会有一个点我可以使用想象的运动。
Before that point, it doesn’t really work.
在那之前,它实际上不起作用。
7:42:53 So if I do calibration for 45 minutes, the first 15 minutes, I can’t use imagined movement.
所以如果我校准 45 分钟,前 15 分钟,我就不能使用想象的运动。
It just doesn’t work for some reason.
它只是由于某种原因不起作用。
And after a certain point, I can just feel it, I can tell.
在某一点之后,我可以感觉到它,我可以说出来。
It moves different.
它的动作不同。
That’s the best way I can describe it.
这是我能描述它的最好方式。
It’s almost as if it is anticipating what I am going to do again, before I go to do it.
就好像它在我去做之前就已经预料到我将要做什么。
And so using attempted movement for 15 minutes, at some point, I can tell when I move my eyes to the next target that the cursor is starting to pick up.
因此,尝试移动 15 分钟后,在某个时刻,当我将眼睛移至下一个目标时,我可以知道光标开始移动。
It’s starting to understand, it’s learning what I’m going to do.
它开始理解,它正在学习我要做什么。
So first of all, it’s really cool that, you are a true pioneer in all of this.
首先,你是这一切领域真正的先驱,这真的很酷。
7:43:41 You’re exploring how to do every aspect of this most effectively and there’s just, I imagine, so many lessons learned from this.
你正在探索如何最有效地完成这件事的各个方面,我想,从中吸取了很多教训。
So thank you for being a pioneer in all these kinds of different super technical ways.
因此,感谢您成为所有这些不同超级技术方法的先驱。
And it’s also cool to hear that there’s a different feeling to the experience when it’s calibrated in different ways because I imagine your brain is doing something different and that’s why there’s a different feeling to it.
听到以不同方式校准时会有不同的体验感觉也很酷,因为我想象你的大脑正在做不同的事情,这就是为什么会有不同的感觉。
And then trying to find the words and the measurements to those feelings would be also interesting.
然后尝试找到这些感受的词语和衡量标准也会很有趣。
But at the end of the day, you can also measure your actual performance, on whether it’s Snake or Webgrid, you could see what actually works well.
但最终,您还可以衡量您的实际性能,无论是 Snake 还是 Webgrid,您都可以看到哪些实际上效果很好。
And you’re saying, for the open loop calibration, the attempted movement works best for now.
你是说,对于开环校准,尝试的运动目前效果最好。
Yep.
是的。
7:44:35 Yep.
是的。
So the open loop, you don’t get the feedback that you did something.
所以在开环中,你不会得到你做了某事的反馈。
Yeah.
是的。
7:44:41 I just-
我只是——
Is that frustrating?
这令人沮丧吗?
7:44:42 [inaudible 07:44:43]-
[听不清 07:44:43]-
No, no, it makes sense to me.
不,不,这对我来说很有意义。
7:44:43 We’ve done it with a cursor and without a cursor in open loop.
我们在开环中使用游标和不使用游标来完成此操作。
So sometimes it’s just, say for the center out, you’ll start calibration with a bubble lighting up and I push towards that bubble, and then when it’s pushed towards that bubble for, say, three seconds, a bubble will pop and then I come back to the middle.
所以有时候,比如说,对于中心向外,你会开始校准,一个气泡亮起,我向那个气泡推动,然后当它被推向那个气泡,比如说三秒钟,一个气泡就会破裂,然后我回到中间。
So I’m doing it all just by my intentions.
所以我只是按照自己的意愿去做这一切。
That’s what it’s learning anyway.
无论如何,这就是它正在学习的内容。
So it makes sense that as long as I follow what they want me to do, follow the yellow brick road, that it’ll all work out.
所以说,只要我按照他们的要求去做,沿着黄砖路走,一切都会成功。
You’re full of great references.
你有很多很棒的参考资料。
7:45:22 Is the bubble game fun?
泡泡游戏好玩吗?
Yeah, they always feel so bad making me do calibration like, oh, we’re about to do a 40-minute calibration.
是的,他们总是让我做校准感觉很糟糕,就像,哦,我们要做一个 40 分钟的校准。
7:45:26 I’m like, “All right, do you guys want to do two of them?” I’m always asking to…
我说:“好吧,你们想做两个吗?”我总是要求……
Whatever they need, I’m more than happy to do.
无论他们需要什么,我都非常乐意做。
And it’s not bad.
这还不错。
I get to lie there or sit in my chair and do these things with some great people.
我可以躺在那里或坐在椅子上与一些伟大的人一起做这些事情。
I get to have great conversations.
我可以进行愉快的交谈。
I can give them feedback.
我可以给他们反馈。
I can talk about all sorts of things.
我可以谈论各种各样的事情。
I could throw something on, on my TV in the background, and split my attention between them.
我可以在电视上放一些东西作为背景,然后将我的注意力分散到它们之间。
It’s not bad at all.
这一点也不坏。
I don’t mind it.
我不介意。
Is there a score that you get?
你得到的分数有吗?
No.
不。
Can you do better on a bubble game?
你能在泡泡游戏中做得更好吗?
No, I would love that.
不,我会喜欢的。
Yeah.
是的。
Yeah, I would love a-
是的,我会喜欢一个-
Writing down suggestions from Noland.
写下诺兰的建议。
That-
那——
Make it more fun, gamified.
让它变得更有趣、更游戏化。
Yeah, that’s one thing that I really, really enjoy about Webgrid is because I’m so competitive.
是的,我真的非常喜欢 Webgrid 的一件事是因为我非常有竞争力。
7:46:20 The higher the BPS, the higher the score, I know the better I’m doing, and so if I…
BPS 越高,分数越高,我知道自己做得越好,所以如果我……
I think I’ve asked at one point, one of the guys, if he could give me some sort of numerical feedback for calibration.
我想我曾经问过其中一个人,他是否可以给我某种用于校准的数字反馈。
I would like to know what they’re looking at.
我想知道他们在看什么。
Like, oh, we see this number while you’re doing calibration, and that means, at least on our end, that we think calibration is going well.
就像,哦,我们在进行校准时看到这个数字,这意味着,至少在我们这边,我们认为校准进展顺利。
And I would love that because I would like to know if what I’m doing is going well or not.
我很乐意这样做,因为我想知道我正在做的事情是否进展顺利。
But then they’ve also told me, yeah, not necessarily one to one.
但后来他们也告诉我,是的,不一定是一对一的。
It doesn’t actually mean that calibration is going well in some ways.
这实际上并不意味着校准在某些方面进展顺利。
So it’s not like a hundred percent and they don’t want to skew what I’m experiencing or want me to change things based on that, if that number isn’t always accurate to how the model will turn out or the end result,.
所以这并不是百分百,他们不想扭曲我正在经历的事情,或者希望我据此改变事情,如果这个数字并不总是准确地反映模型的结果或最终结果。
That’s at least what I got from it.
这至少是我从中得到的。
7:47:19 One thing I have asked them, and something that I really enjoy striving for, is towards the end of calibration, there is a time between targets.
我问过他们的一件事,也是我真正喜欢努力争取的一件事,就是在校准结束时,目标之间有一个时间间隔。
And so I like to keep, at the end, that number as low as possible.
因此,我希望最终将这个数字保持在尽可能低的水平。
So at the beginning it can be four or five, six seconds between me popping bubbles, but towards the end I like to keep it below 1.5 or if I could get it to one second between bubbles.
所以一开始,我弹出气泡的间隔可能是四、五、六秒,但到了最后,我喜欢将其保持在 1.5 以下,或者如果我能让气泡之间的间隔达到一秒。
Because in my mind, that translates really nicely to something like Webgrid, where I know if I can hit a target, one every second, that I’m doing real, real well.
因为在我看来,这可以很好地转化为 Webgrid 之类的东西,我知道我是否可以每秒一个目标,我做得非常非常好。
There you go.
就这样吧。
7:47:58 That’s a way to get a score on the calibrations, like the speed.
这是一种获得校准分数的方法,比如速度。
How quickly can you get from bubble to bubble?
你能多快从一个泡沫到另一个泡沫?
Yeah.
是的。
So there’s the open loop and then it goes to the closed loop.
所以先是开环,然后进入闭环。
Closed loop.
闭环。
And the closed loop can already start giving you a sense because you’re getting feedback of how good the model is.
闭环已经开始给你一种感觉,因为你得到了关于模型有多好的反馈。
Yeah.
是的。
7:48:13 Yeah.
是的。
So closed loop is when I first get cursor control, and how they’ve described it to me, someone who does not understand this stuff, I am the dumbest person in the room every time I’m with any of those guys.
所以闭环是当我第一次获得光标控制时,以及他们如何向我描述它的,一个不理解这些东西的人,每次我和这些人中的任何一个在一起时,我都是房间里最愚蠢的人。
I love the humility.
我喜欢谦虚。
I appreciate it.
我很感激。
Yeah, is that I am closing the loop.
是的,我正在关闭循环。
7:48:27 So I am actually now the one that is finishing the loop of whatever this loop is.
所以我现在实际上是正在完成这个循环的人。
I don’t even know what the loop is.
我什至不知道循环是什么。
They’ve never told me.
他们从来没有告诉过我。
They just say there is a loop and at one point it’s open and I can’t control, and then I get control and it’s closed.
他们只是说存在一个循环,在某一时刻它是开放的,我无法控制,然后我得到控制,它就关闭了。
So I’m finishing the loop.
所以我正在完成循环。
So how long the calibration usually take?
那么校准通常需要多长时间?
7:48:48 You said 10, 15 minutes, [inaudible 07:48:52]-
你说 10、15 分钟,[听不清 07:48:52]-
Well, yeah, they’re trying to get that number down pretty low.
嗯,是的,他们正在努力将这个数字降低到相当低的水平。
7:48:52 That’s what we’ve been working on a lot recently, is getting that down is low as possible.
这就是我们最近一直在努力的方向,就是尽可能降低这一点。
So that way, if this is something that people need to do on a daily basis or if some people need to do on a every-other-day basis or once a week, they don’t want people to be sitting in calibration for long periods of time.
这样,如果这是人们每天需要做的事情,或者如果有些人需要每隔一天或每周做一次,他们不希望人们长时间坐在校准中。
I think they’ve wanted to get it down seven minutes or below, at least where we’re at right now.
我认为他们希望把时间缩短到七分钟或更少,至少我们现在是这样。
It’d be nice if you never had to do calibration.
如果您不需要进行校准,那就太好了。
So we’ll get there at some point, I’m sure, the more we learn about the brain, and I think that’s the dream.
因此,我确信,随着我们对大脑了解得越多,我们一定会在某个时候实现这一目标,我认为这就是梦想。
I think right now, for me to get really, really good models, I’m in calibration 40 or 45 minutes.
我认为现在,为了获得非常非常好的模型,我需要校准 40 或 45 分钟。
And I don’t mind, like I said, they always feel really bad, but if it’s going to get me a model that can break these records on Webgrid, I’ll stay in it for flipping two hours.
我并不介意,就像我说的,他们总是感觉很糟糕,但如果它能给我一个可以打破 Webgrid 上这些记录的模型,我会在里面待上两个小时。
Let’s talk business.
我们来谈谈生意吧。
7:49:50 So Webgrid, I saw a presentation where Bliss said by March you selected 89,000 targets in Webgrid.
Webgrid,我看到了一个演示,Bliss 说到 3 月份,您在 Webgrid 中选择了 89,000 个目标。
Can you explain this game?
你能解释一下这个游戏吗?
What is Webgrid and what does it take to be a world-class performer in Webgrid, as you continue to break world records?
什么是 Webgrid?当您不断打破世界纪录时,怎样才能成为 Webgrid 中的世界级表演者?
Yeah.
是的。
It’s like a gold medalist talk.
这就像金牌得主的演讲。
7:50:10 Well, where do I begin?
好吧,我从哪里开始呢?
Yeah, I’d like thank-
是的,我想谢谢-
Yeah, exactly.
是的,完全正确。
…
……
7:50:18 everyone who’s helped me get here, my coaches, my parents, for driving me to practice every day at 5:00 in the morning.
所有帮助我来到这里的人,我的教练,我的父母,他们每天早上 5:00 开车送我去训练。
I like to thank God and just overall my dedication to my craft.
我要感谢上帝,感谢我对我的手艺的奉献。
[inaudible 07:50:29].
[听不清 07:50:29]。
Yeah, the interviews with athletes, they’re always like that exact-
是的,对运动员的采访,他们总是那样——
Yeah.
是的。
It’s that template.
就是那个模板。
Yeah, so-
是啊,所以——
So Webgrid, is a-
所以 Webgrid 是一个——
Webgrid is a-
网络网格是一个-
…
……
7:50:37 grid of cells.
细胞网格。
Yeah, it’s literally just a grid.
是的,它实际上只是一个网格。
7:50:41 They can make it as big or small as you can make a grid.
他们可以把它做得像你可以制作一个网格一样大或小。
A single box on that grid will light up and you go and click it.
该网格上的一个框将会亮起,您可以单击它。
And it is a way for them to benchmark how good a BCI is.
这是他们衡量 BCI 性能的一种方法。
So it’s pretty straightforward.
所以这非常简单。
You just click targets.
您只需单击目标即可。
Only one blue cell appears and you’re supposed to move the mouse to there and click on it.
仅出现一个蓝色单元格,您应该将鼠标移至那里并单击它。
Yep.
是的。
7:51:06 So I like playing on bigger grids because the bigger the grid, the more BPS, it’s bits per second, that you get every time you click one.
所以我喜欢在更大的网格上玩,因为网格越大,BPS 就越多,即每秒的比特数,每次单击一个网格时都会得到更多的数据。
So I’ll say I’ll play on a 35 by 35 grid, and then one of those little squares, a cell, you can call it, target, whatever, will light up.
所以我会说我会在 35 x 35 的网格上玩,然后其中一个小方块,一个单元格,你可以称之为目标,无论什么,都会亮起。
And you move the cursor there, and you click it, and then you do that forever.
然后你将光标移到那里,然后单击它,然后你就永远这样做。
And you’ve been able to achieve, at first, eight bits per second, then you’ve recently broke that.
一开始你已经能够达到每秒八位,然后你最近打破了这个目标。
Yeah.
是的。
7:51:40 Yeah, I’m at 8.5 right now.
是的,我现在8.5。
I would’ve beaten that literally the day before I came to Austin.
在我来奥斯汀的前一天,我真的会打败它。
But I had a, I don’t know, a five-second lag right at the end, and I just had to wait until the latency calmed down, and then I kept clicking.
但我不知道,最后有一个五秒的延迟,我只需要等到延迟平静下来,然后我就继续点击。
But I was at 8.01, and then five seconds of lag, and then the next three targets I clicked all stayed at 8.01.
但我当时是 8.01,然后有五秒的延迟,然后我点击的接下来的三个目标都停留在 8.01。
So if I would’ve been able to click during that time of lag, I probably would’ve hit, I don’t know, I might’ve hit nine.
因此,如果我能够在延迟期间点击,我可能会点击,我不知道,我可能会点击九个。
So I’m there.
所以我就在那里。
I’m really close, and then this whole Austin trip has really gotten in the way of my Webgrid playing ability.
我真的很接近了,然后整个奥斯汀之旅真的阻碍了我的 Webgrid 演奏能力。
It’s frustrating.
这很令人沮丧。
Yeah, it’s-
是的,这是——
So that’s all-
这就是全部——
I’ve been itching.
我已经心痒痒了。
…
……
7:52:26 you’ve thinking about right now?
你现在在想什么?
Yeah, I know.
是的,我知道。
I just want to do better.
我只是想做得更好。
At nine.
九点。
I want to do better.
我想做得更好。
7:52:28 I want to hit nine, I think, well, I know nine is very, very achievable.
我想达到九,我想,嗯,我知道九是非常非常可以实现的。
I’m right there.
我就在那里。
I think 10 I could hit, maybe in the next month.
我想我可能会在下个月打到10。
I could do it probably in the next few weeks if I really push.
如果我真的努力的话,我可能会在接下来的几周内做到这一点。
I think you and Elon are basically the same person because last time I did a podcast with him, he came in extremely frustrated that he can’t beat Uber Lilith as a Druid.
我认为你和埃隆基本上是同一个人,因为上次我和他一起做播客时,他非常沮丧,因为他作为德鲁伊无法击败尤伯莉莉丝。
[inaudible 07:52:51].
[听不清 07:52:51]。
That was a year ago, I think, I forget, solo.
那是一年前的事了,我想,我忘了,独自一人。
7:52:50 And I could just tell there’s some percentage of his brain, the entire time was thinking, “I wish I was right now attempting.” [inaudible 07:53:01]-
我可以看出他的大脑中有一部分一直在想,“我希望我现在就在尝试。” [听不清 07:53:01]-
Yeah.
是的。
7:53:01 I think he did it that night.
我想他那天晚上就这么做了。
He did it that night.
那天晚上他就这么做了。
7:53:06 He stayed up and did it that night, which is crazy to me.
那天晚上他熬夜做了这件事,这对我来说太疯狂了。
In a fundamental way, it’s really inspiring and what you’re doing is inspiring in that way because it’s not just about the game.
从根本上来说,这真的很鼓舞人心,而你所做的事情也以这种方式鼓舞人心,因为这不仅仅是关于游戏。
Everything you’re doing there has impact.
你在那里所做的一切都会产生影响。
By striving to do well on Webgrid, you’re helping everybody figure out how to create the system all along the decoding, the software, the hardware, the calibration, all of it.
通过努力在 Webgrid 上取得好成绩,您可以帮助每个人弄清楚如何从解码、软件、硬件、校准等所有方面创建系统。
How to make all of that work so you can do everything else really well.
如何使所有这些工作顺利进行,以便您可以很好地完成其他所有事情。
Yeah, it’s just really fun.
是的,这真的很有趣。
Well, that’s also, that’s part of the thing, is that making it fun.
嗯,这也是事情的一部分,那就是让它变得有趣。
Yeah, it’s a addicting.
是的,这很让人上瘾。
7:53:42 I’ve joked about what they actually did when they went in and put this thing in my brain.
我开玩笑说他们把这个东西放进我的大脑时实际上做了什么。
They must’ve flipped a switch to make me more susceptible to these kinds of games, to make me addicted to Webgrid or something.
他们一定是按下了开关,让我更容易沉迷于这类游戏,让我沉迷于 Webgrid 之类的东西。
Yeah.
是的。
Do you know Bliss’s high score?
你知道布利斯的高分吗?
Yeah, he said like 14 or something.
是的,他说大概14岁左右。
17.
17.
Oh, boy.
哦,男孩。
17.1 or something.
17.1什么的。
7:54:04 17.01?
17.01?
17 on the dot.
17 点。
17-
17-
17.01.
17.01。
Yeah.
是的。
He told me he does it on the floor with peanut butter and he fasts.
他告诉我他是在地板上用花生酱做的,而且他禁食。
7:54:09 It’s weird.
这很奇怪。
That sounds like cheating.
这听起来像是作弊。
Sounds like performance enhancing-
听起来像是性能增强-
Noland, the first time Noland played this game, he asked how good are we at this game?
诺兰德,诺兰德第一次玩这个游戏,他问我们这个游戏打得怎么样?
7:54:17 And I think you told me right then, you’re going to try to beat me [inaudible 07:54:24]-
我想你当时就告诉我,你会试图打败我 [听不清 07:54:24]-
I’m going to get there someday.
总有一天我会到达那里。
Yeah, I fully believe you.
是的,我完全相信你。
I think I can.
我想我可以。
7:54:26 I think I can.
我想我可以。
I think-
我认为——
I’m excited for that.
我对此感到很兴奋。
Yeah.
是的。
7:54:28 So I’ve been playing, first off, with the dwell cursor, which really hampers my Webgrid playing ability.
因此,我首先使用停留光标进行游戏,这确实妨碍了我的 Webgrid 游戏能力。
Basically I have to wait 0.3 seconds for every click.
基本上每次点击我都要等待0.3秒。
Oh, so you can’t do the click.
哦,所以你不能点击。
7:54:40 So you click by dwelling, you said 0.3.
所以你按住处点击,你说0.3。
0.3 seconds, which sucks.
0.3秒,太糟糕了。
7:54:45 It really slows down how high I’m able to get.
它确实减慢了我达到的高度。
I still hit 50, I think I hit 50-something net trials per minute in that, which was pretty good because I’m able to…
我仍然达到了 50,我想我每分钟达到了 50 次左右的净尝试,这非常好,因为我能够……
One of the settings is also how slow you need to be moving in order to initiate a click, to start a click.
其中一项设置也是您需要移动多慢才能启动单击,开始单击。
So I can tell, sort of, when I’m on that threshold, to start initiating a click just a bit early.
因此,当我达到该阈值时,我可以稍微提前一点开始启动点击。
So I’m not fully stopped over the target when I go to click, I’m doing it on my way to the targets a little, to try to time it just right.
所以当我去点击时,我并没有完全停在目标上,我只是在到达目标的路上稍微做一下,试图恰到好处地计时。
Oh, wow.
哦,哇。
Yeah.
是的。
So you’re slowing down.
所以你放慢了速度。
Yeah, just a hair, right before the targets.
是的,就在目标之前的一根头发上。
This is like elite performance.
这就像精英表演一样。
7:55:34 Okay, but that’s still, it sucks that there’s a ceiling of the 0.3.
好吧,但仍然如此,0.3 的上限很糟糕。
Well, I can get down to 0.2 and 0.1.
好吧,我可以降到 0.2 和 0.1。
7:55:41 0.1’s what I’ve-
0.1就是我的-
[inaudible 07:55:45].
[听不清 07:55:45]。
Yeah, and I’ve played with that a little bit too.
是的,我也玩过一点。
7:55:45 I have to adjust a ton of different parameters in order to play with 0.1, and I don’t have control over all of that on my end yet.
我必须调整大量不同的参数才能使用 0.1,但我还无法控制所有这些。
It also changes how the models are trained.
它还改变了模型的训练方式。
If I train a model, like in Webgrid, I bootstrap on a model, which basically is them training models as I’m playing Webgrid based off of the Webgrid data that I’m…
如果我训练一个模型,就像在 Webgrid 中一样,我会引导一个模型,这基本上是当我根据我正在玩的 Webgrid 数据来训练模型时......
So if I play Webgrid for 10 minutes, they can train off that data specifically in order to get me a better model.
因此,如果我玩 Webgrid 10 分钟,他们就可以专门训练这些数据,以便为我提供更好的模型。
If I do that with 0.3 versus 0.1, the models come out different.
如果我使用 0.3 与 0.1 进行比较,模型就会有所不同。
The way that they interact, it’s just much, much different.
他们互动的方式非常非常不同。
So I have to be really careful.
所以我必须非常小心。
I found that doing it with 0.3 is actually better in some ways.
我发现使用 0.3 实际上在某些方面更好。
Unless I can do it with 0.1 and change all of the different parameters, then that’s more ideal, because obviously 0.3 is faster than 0.1.
除非我可以用 0.1 做到这一点并更改所有不同的参数,否则那就更理想了,因为显然 0.3 比 0.1 更快。
So I could get there.
这样我就可以到达那里。
I can get there.
我可以到达那里。
Can you click using your brain?
你能用脑子点击吗?
For right now, it’s the hover clicking with the dwell cursor.
现在,是使用停留光标进行悬停单击。
7:56:45 Before all the thread retraction stuff happened, we were calibrating clicks, left click, right click.
在所有螺纹回缩发生之前,我们正在校准点击、左键点击、右键点击。
That was my previous ceiling, before I broke the record again with the dwell cursor, was I think on a 35 by 35 grid with left and right click.
这是我之前的上限,在我用停留光标再次打破记录之前,我认为在 35 x 35 网格上单击鼠标左键和右键。
And you get more BPS, more bits per second, using multiple clicks because it’s more difficult.
通过多次点击,您可以获得更多的 BPS、每秒更多的比特数,因为这更困难。
Oh, because what is it, you’re supposed to do either a left click or a right click?
哦,因为这是什么,你应该点击左键还是右键?
Yes.
是的。
Is a different colors, something like this?
是不是有不同的颜色,类似这样的?
Different colors.
不同的颜色。
Cool.
凉爽的。
7:57:18 Cool.
凉爽的。
Yeah, blue targets for left click, orange targets for right click is what they had done.
是的,左键单击的蓝色目标,右键单击的橙色目标就是他们所做的。
Got it.
知道了。
So my previous record of 7.5-
所以我之前的记录是7.5-
Was with the two clicks.
点击两次即可。
…
……
7:57:27 was with the blue and the orange targets, yeah, which I think if I went back to that now, doing the click calibration, I would be able to…
是蓝色和橙色目标,是的,我想如果我现在回到那个位置,进行点击校准,我将能够......
And being able to initiate clicks on my own, I think I would break that 10 ceiling in a couple days, max.
如果能够自己发起点击,我想我最多会在几天内突破 10 个上限。
Yeah, you would start making Bliss nervous about his 17.
是的,你会让布利斯开始为他的 17 岁感到紧张。
Yeah, he should be.
是的,他应该是。
Why do you think we haven’t given him the-
你认为我们为什么没有给他——
Yeah.
是的。
Exactly.
确切地。
7:57:49 Exactly.
确切地。
So what did it feel like with the retractions, that some of the threads are retracted?
那么,撤回时感觉如何,某些线程被撤回了?
It sucked.
太糟糕了。
7:57:57 It was really, really hard.
这真的非常非常难。
The day they told me was the day of my big Neuralink tour at their Fremont facility.
他们告诉我的那天是我在弗里蒙特工厂进行 Neuralink 大型巡演的日子。
They told me right before we went over there.
他们在我们去那里之前告诉了我。
It was really hard to hear.
真的很难听。
My initial reaction was, all right, go in, fix it.
我的第一反应是,好吧,进去修复它。
Go in, take it out and fix it.
进去,拿出来修好。
The first surgery was so easy.
第一次手术就这么简单。
I went to sleep, a couple hours later I woke up and here we are.
我睡着了,几个小时后我醒来,我们到了。
I didn’t feel any pain, didn’t take any pain pills or anything.
我没有感到任何疼痛,也没有服用任何止痛药或任何东西。
So I just knew that if they wanted to, they could go in and put in a new one next day if that’s what it took because I wanted it to be better and I wanted not to lose the capability.
所以我只知道,如果他们愿意,他们可以在第二天放入新的,如果这是需要的话,因为我希望它变得更好,并且我不想失去能力。
I had so much fun playing with it for a few weeks, for a month.
我玩了几周甚至一个月,玩得很开心。
It had opened up so many doors for me.
它为我打开了很多扇门。
It had opened up so many more possibilities that I didn’t want to lose it after a month.
它开启了更多的可能性,我不想在一个月后失去它。
7:58:58 I thought it would’ve been a cruel twist of fate if I had gotten to see the view from the top of this mountain and then have it all come crashing down after a month.
我想,如果我能从这座山顶看到风景,然后一个月后一切都轰然倒塌,那将是命运的残酷转折。
And I knew, I say the top of the mountain, but how I saw it was I was just now starting to climb the mountain and there was so much more that I knew was possible.
我知道,我说的是山顶,但我所看到的是我现在才开始爬山,我知道还有很多事情是可能的。
And so to have all of that be taken away was really, really hard.
因此,要剥夺所有这些真的非常非常困难。
But then on the drive over to the facility, I don’t know, five minute drive, whatever it is, I talked with my parents about it.
但后来在开车去设施的路上,我不知道,五分钟车程,不管是什么,我和我的父母谈论了这件事。
I prayed about it.
我为此祈祷。
I was just like, I’m not going to let this ruin my day.
我当时想,我不会让这件事毁了我的一天。
I’m not going to let this ruin this amazing tour that they have set up for me.
我不会让这毁了他们为我安排的这次精彩的旅行。
I want to go show everyone how much I appreciate all the work they’re doing.
我想向大家展示我是多么欣赏他们所做的所有工作。
7:59:54 I want to go meet all of the people who have made this possible, and I want to go have one of the best days of my life, and I did.
我想去见见所有使这一切成为可能的人,我想去度过我一生中最美好的日子之一,我做到了。
And it was amazing, and it absolutely was one of the best days I’ve ever been privileged to experience.
这真是太棒了,这绝对是我有幸经历过的最好的日子之一。
And then for a few days I was pretty down in the dumps, but for the first few days afterwards, I didn’t know if it was ever going to work again.
然后有几天我心情很低落,但在之后的头几天,我不知道它是否还能再次发挥作用。
And then I made the decision that, even if I lost the ability to use the Neuralink, even if I lost out on everything to come, if I could keep giving them data in any way, then I would do that.
然后我决定,即使我失去了使用 Neuralink 的能力,即使我失去了未来的一切,如果我能继续以任何方式向他们提供数据,那么我就会这么做。
8:00:41 If I needed to just do some of the data collection every day or body mapping every day for a year, then I would do it because I know that everything I’m doing helps everyone to come after me, and that’s all I wanted.
如果我只需要一年内每天收集一些数据或每天进行身体绘图,那么我会这样做,因为我知道我所做的一切可以帮助每个人追随我,而这就是我想要的。
Just the whole reason that I did this was to help people, and I knew that anything I could do to help, I would continue to do, even if I never got to use the cursor again, then I was just happy to be a part of it.
我这样做的全部原因是为了帮助人们,我知道任何我能做的事情我都会继续做,即使我再也不会使用光标,那么我很高兴成为其中的一部分。
And everything that I had done was just a perk.
而我所做的一切都只是一种额外的福利。
It was something that I got to experience, and I know how amazing it’s going to be for everyone to come after me.
这是我必须经历的事情,我知道每个人都追随我将是多么令人惊奇。
So might as well just keep trucking along.
所以不妨继续卡车运输。
Well, that said, you were able to get to work your way up, to get the performance back.
嗯,也就是说,你能够继续努力,恢复表现。
8:01:22 So this is like going from Rocky I to Rocky II.
所以这就像从《洛奇一号》到《洛奇二号》一样。
So when did you first realize that this is possible, and what gave you the strength, the motivation, the determination to do it, to increase back up and beat your previous record?
那么,您什么时候第一次意识到这是可能的?是什么给了您力量、动力和决心去做这件事,以增加备份并打破您之前的记录?
Yeah, it was within a couple weeks, [inaudible 08:01:44]-
是的,就在几周之内,[听不清 08:01:44]-
Again, this feels like I’m interviewing an athlete.
再说一次,这感觉就像我在采访一名运动员。
8:01:44 This is great.
这太棒了。
I’d like thank my parents.
我要感谢我的父母。
The road back was long and hard-
回去的路漫长而艰难——
[inaudible 08:01:53] like a movie.
[听不清 08:01:53] 就像电影一样。
…
……
8:01:53 fraught with many difficulties.
充满了许多困难。
There were dark days.
也有过黑暗的日子。
It was a couple weeks, I think, and then there was just a turning point.
我想,那是几周后的事情,然后就出现了一个转折点。
I think they had switched how they were measuring the neuron spikes in my brain, the…
我认为他们改变了测量我大脑中神经元尖峰的方式,......
Bliss help me out.
幸福来帮我吧。
Yeah, the way in which we were measuring the behavior of individual neurons.
是的,我们测量单个神经元行为的方式。
Yeah.
是的。
So we’re switching from individual spike detection to something called spike band power, which if you watch the previous segments with either me or DJ, you probably have some [inaudible 08:02:26]-
因此,我们正在从单独的尖峰检测切换到称为尖峰带功率的东西,如果您与我或 DJ 一起观看之前的片段,您可能会有一些[听不清 08:02:26]-
Yeah, okay.
是啊,好吧。
Mm-hmm.
嗯嗯。
So when they did that, it was like a light over the head, light bulb moment, like, oh, this works and this seems like we can run with this.
所以当他们这样做时,就像头顶上有一盏灯,灯泡瞬间亮了,就像,哦,这行得通,看起来我们可以用它来运行。
8:02:27 And I saw the uptick in performance immediately.
我立即看到了性能的提升。
I could feel it when they switched over.
当他们切换时我能感觉到。
I was like, “This is better.
我当时想,“这更好。
This is good.
这很好。
Everything up until this point,” for the last few weeks, last, whatever, three or four weeks because it was before they even told me, “Everything before this sucked.
到目前为止的一切,”过去几周,最后,无论如何,三四个星期,因为那是在他们告诉我之前,“在此之前的一切都很糟糕。
Let’s keep doing what we’re doing now.” And at that point it was not like, oh, I know I’m still only at, say in Webgrid terms, four or five BPS compared to my 7.5 before, but I know that if we keep doing this, then I can get back there.
让我们继续做我们现在正在做的事情。”那时,情况并不是这样的,哦,我知道,用 Webgrid 的术语来说,与之前的 7.5 个 BPS 相比,我仍然只有四到五个 BPS,但我知道,如果我们继续这样做,那么我可以回到那里。
And then they gave me the dwell cursor and the dwell cursor sucked at first.
然后他们给了我停留光标,停留光标一开始很糟糕。
It’s obviously not what I want, but it gave me a path forward to be able to continue using it and hopefully to continue to help out.
这显然不是我想要的,但它为我提供了一条继续使用它的道路,并希望继续提供帮助。
And so I just ran with it, never looked back.
所以我就这样跑了,再也没有回头。
Like I said, I’m just kind of person, I roll with the punches anyway.
就像我说的,我只是一个人,无论如何我都会迎难而上。
So-
所以——
What was the process?
过程是怎样的?
8:03:37 What was the feedback loop on the figuring out how to do the spike detection in a way that would actually work well for Noland?
在弄清楚如何以一种对诺兰来说真正有效的方式进行尖峰检测时,反馈循环是什么?
Yeah, it’s a great question.
是的,这是一个很好的问题。
8:03:45 So maybe just to describe first how the actual update worked.
所以也许只是先描述一下实际更新是如何工作的。
It was basically an update to your implant.
这基本上是对您的植入物的更新。
So we just did an over-the-air software update to his implants, same way you’d update your Tesla or your iPhone.
所以我们只是对他的植入物进行了无线软件更新,就像更新你的 Tesla 或 iPhone 一样。
And that firmware change enabled us to record averages of populations of neurons nearby individual electrodes.
这种固件变化使我们能够记录单个电极附近神经元群体的平均值。
So we have less resolution about which individual neuron is doing what, but we have a broader picture of what’s going on nearby an electrode overall.
因此,我们对哪个神经元正在做什么的分辨率较低,但我们对电极附近整体发生的情况有更广泛的了解。
And that feedback loop, basically as Noland described it, it was immediate when we flipped that switch.
基本上正如诺兰所描述的那样,当我们按下开关时,反馈循环就立即出现了。
I think the first day we did that, you had three or four BPS right out of the box, and that was a light bulb moment for, okay, this is the right path to go down.
我认为我们这样做的第一天,开箱即用的 BPS 就达到了三到四个,那是一个灵光一闪的时刻,好吧,这是正确的道路。
And from there, there’s a lot of feedback around how to make this useful for independent use.
从那里开始,有很多关于如何使其可用于独立使用的反馈。
8:04:27 So what we care about ultimately is that you can use it independently to do whatever you want.
所以我们最终关心的是你可以独立使用它来做你想做的事情。
And to get to that point, it required us to re-engineer the UX, as you talked about with the dwell cursor, to make it something that you can use independently without us needing to be involved all the time.
为了达到这一点,它需要我们重新设计用户体验,正如您谈到的停留光标一样,使其成为您可以独立使用的东西,而无需我们一直参与。
And yeah, this is obviously the start of this journey still.
是的,这显然仍然是这段旅程的开始。
Hopefully we get back to the places where you’re doing multiple clicks and using that to control, much more fluidly, everything, and much more naturally the applications that you’re trying to interface with.
希望我们能回到您进行多次单击并使用它来更流畅地控制一切的地方,并且更自然地控制您尝试与之交互的应用程序。
And most importantly, get that Webgrid number up.
最重要的是,提高 Webgrid 的数量。
Yep.
是的。
Yes.
是的。
8:04:55 [inaudible 08:04:57].
[听不清 08:04:57]。
Yeah.
是的。
So how is, on the hover click, do you accidentally click stuff sometimes?
那么,在悬停点击时,您有时会不小心点击一些东西吗?
Yep.
是的。
How hard is it to avoid accidentally clicking?
避免意外点击有多难?
I have to continuously keep it moving, basically.
基本上,我必须不断地让它继续前进。
8:05:05 So like I said, there’s a threshold where it will initiate a click.
正如我所说,启动点击有一个阈值。
So if I ever drop below that, it’ll start and I have 0.3 seconds to move it before it clicks anything.
因此,如果我低于该值,它就会启动,并且在它发出任何声音之前我有 0.3 秒的时间来移动它。
[inaudible 08:05:21].
[听不清 08:05:21]。
And if I don’t want it to ever get there, I just keep it moving at a certain speed and just constantly doing circles on screen, moving it back and forth, to keep it from clicking stuff.
如果我不想让它到达那里,我只需让它以一定的速度移动,并不断在屏幕上画圈,来回移动它,以防止它点击东西。
8:05:20 I actually noticed, a couple weeks back, that when I was not using the implant, I was just moving my hand back and forth or in circles.
事实上,几周前我注意到,当我不使用植入物时,我只是来回移动我的手或画圈。
I was trying to keep the cursor from clicking and I was just doing it while I was trying to go to sleep.
我试图阻止光标点击,而我只是在试图睡觉时这样做。
And I was like, “Okay, this is a problem.” [inaudible 08:05:52].
我当时想,“好吧,这是一个问题。” [听不清 08:05:52]。
[inaudible 08:05:51].
[听不清 08:05:51]。
To avoid the clicking.
以避免点击。
8:05:52 I guess, does that create problems when you’re gaming, accidentally click a thing?
我想,当你玩游戏时,不小心点击某个东西,这会产生问题吗?
Like-
就像-
Yeah.
是的。
8:05:58 Yeah.
是的。
It happens in chess.
这发生在国际象棋中。
Accidental, yeah.
意外,是的。
I’ve lost a number of games because I’ll accidentally click something.
我输掉了很多游戏,因为我不小心点击了某些东西。
I think the first time I ever beat you was because of an accidental click.
我想我第一次打败你是因为不小心点击了。
Yeah, a misclick.
是的,按错了。
8:06:06 Yeah.
是的。
It’s a nice excuse, right?
这是一个很好的借口,对吧?
8:06:10 You can always-
你总是可以——
Yeah, [inaudible 08:06:12] it’s great.
是的,[听不清 08:06:12] 太棒了。
8:06:12 It’s perfect.
太完美了。
…
……
anytime you lose, you could just say, “That was accidental.”
任何时候你输了,你都可以说:“那是偶然的。”
Yeah.
是的。
8:06:15 Yeah.
是的。
You said the app improved a lot from version one when you first started using it.
您说该应用程序比您第一次开始使用时的第一版改进了很多。
8:06:16 It was very different.
这是非常不同的。
So can you just talk about the trial and error that you went through with the team?
那么您能谈谈您与团队一起经历的尝试和错误吗?
200 plus pages of notes.
200多页笔记。
What’s that process like of going back and forth and working together to improve the thing?
来来回回并共同努力改进事物的过程是什么样的?
It’s a lot of me just using it day in and day out and saying, “Hey, can you guys do this for me?
我很多人只是日复一日地使用它并说:“嘿,你们能为我做这个吗?
8:06:36 Give me this.
给我这个。
I want to be able to do that.
我希望能够做到这一点。
I need this.” I think a lot of it just doesn’t occur to them maybe, until someone is actually using the app, using the implant.
我需要这个。”我认为很多事情可能只是他们没有想到,直到有人真正使用该应用程序,使用植入物。
It’s just something that they just never would’ve thought of or it’s very specific to even me, maybe what I want.
这只是他们永远不会想到的事情,或者甚至对我来说也是非常具体的,也许是我想要的。
It’s something I’m a little worried about with the next people that come is maybe they will want things much different than how I’ve set it up or what the advice I’ve given the team, and they’re going to look at some of the things they’ve added for me.
我对接下来的人有点担心,也许他们想要的东西与我的设置方式或我给团队的建议大不相同,他们会看看他们为我添加的一些东西。
[inaudible 08:07:26] like, “That’s a dumb idea.
[听不清 08:07:26] 就像,“这是一个愚蠢的想法。
Why would he ask for that?” And so I’m really looking forward to get the next people on because I guarantee that they’re going to think of things that I’ve never thought of.
他为什么要提出这样的要求?”所以我真的很期待让下一个人加入,因为我保证他们会想到我从未想过的事情。
8:07:37 They’re going to think of improvements something like, wow, that’s a really good idea.
他们会想到一些改进,比如,哇,这真是个好主意。
I wish I would’ve thought of that.
我希望我能想到这一点。
And then they’re also going to give me some pushback about, yeah, what you are asking them to do here, that’s a bad idea.
然后他们也会给我一些阻力,是的,你要求他们在这里做什么,这是一个坏主意。
Let’s do it this way.
让我们这样做吧。
And I’m more than happy to have that happen, but it’s just a lot of different interactions with different games or applications, the internet, just with the computer in general.
我非常高兴发生这种情况,但这只是与不同游戏或应用程序、互联网以及一般计算机的许多不同交互。
There’s tons of bugs that end up popping up, left, right, center.
最终会出现大量错误,左、右、中。
8:08:11 So it’s just me trying to use it as much as possible and showing them what works and what doesn’t work, and what I would like to be better.
所以我只是尝试尽可能多地使用它,并向他们展示什么有效,什么无效,以及我希望做得更好。
And then they take that feedback and they usually create amazing things for me.
然后他们接受反馈,通常会为我创造出令人惊奇的东西。
They solve these problems in ways I would’ve never imagined.
他们以我从未想象过的方式解决这些问题。
They’re so good at everything they do, and so I’m just really thankful that I’m able to give them feedback and they can make something of it, because a lot of my feedback is really dumb.
他们所做的每一件事都非常擅长,所以我真的很感激我能够给他们反馈,他们可以利用它,因为我的很多反馈真的很愚蠢。
It’s just like, “I want this, please do something about it,” and it’ll come back, super well-thought-out, and it’s way better than anything I could have ever thought of or implemented myself.
就像,“我想要这个,请做点什么”,它会回来,经过深思熟虑,它比我自己想到或实现的任何东西都要好。
So they’re just great.
所以他们很棒。
They’re really, really cool.
他们真的非常非常酷。
As the BCI community grows, would you like to hang out with the other folks with Neuralinks?
随着 BCI 社区的发展,您想与其他使用 Neuralinks 的人一起出去玩吗?
8:08:53 What relationship, if any, would you want to have with them?
如果有的话,您想与他们建立什么关系?
Because you said they might have a different set of ideas of how to use the thing.
因为你说他们对于如何使用这个东西可能有一套不同的想法。
Yeah.
是的。
Would you be intimidated by their Webgrid performance?
您会被他们的 Webgrid 性能吓倒吗?
No.
不。
8:09:13 No.
不。
I hope-
我希望——
Compete.
竞争。
I hope, day one, they wipe the floor with me.
我希望第一天他们就和我一起擦地板。
8:09:15 I hope they beat it and they crush it, double it if they can, just because on one hand it’s only going to push me to be better because I’m super competitive.
我希望他们能打败它,粉碎它,如果可以的话,加倍,只是因为一方面,这只会促使我变得更好,因为我超级有竞争力。
I want other people to push me.
我希望其他人能推动我。
I think that is important for anyone trying to achieve greatness is they need other people around them who are going to push them to be better.
我认为对于任何想要取得伟大成就的人来说,这一点很重要,因为他们需要身边有其他人来推动他们变得更好。
And I even made a joke about it on X once, once the next people get chosen, cue buddy cop music.
我什至在 X 上开过一次玩笑,一旦选择了下一个人,就提示好友警察音乐。
I’m just excited to have other people to do this with and to share experiences with.
我很高兴能与其他人一起做这件事并分享经验。
I’m more than happy to interact with them as much as they want, more than happy to give them advice.
我非常乐意与他们互动,非常乐意为他们提供建议。
I don’t know what kind of advice I could give them, but if they have-
我不知道我能给他们什么样的建议,但如果他们有——
8:10:00 …
……
give them advice.
给他们建议。
I don’t know what advice I could give them, but if they have questions, I’m more than happy.
我不知道我能给他们什么建议,但如果他们有疑问,我会非常高兴。
What advice would you have for the next participant in the clinical trial?
您对临床试验的下一位参与者有什么建议?
That they should have fun with this, because it is a lot of fun, and that I hope they work really, really hard because it’s not just for us, it’s for everyone that comes after us.
他们应该从中获得乐趣,因为这很有趣,我希望他们非常非常努力地工作,因为这不仅是为了我们,也是为了我们之后的每个人。
8:10:10 And come to me if they need anything.
如果他们需要什么就来找我。
And to go to Neuralink if they need anything.
如果他们需要什么就去 Neuralink。
Man, Neuralink moves mountains.
伙计,Neuralink 可以移山。
They do absolutely anything for me that they can, and it’s an amazing support system to have.
他们绝对会为我做任何力所能及的事情,这是一个令人惊叹的支持系统。
It puts my mind at ease for so many things that I have had questions about or so many things I want to do, and they’re always there, and that’s really, really nice.
它让我对很多我有疑问的事情或很多我想做的事情感到放心,而且它们总是在那里,这真的非常好。
And so I would tell them not to be afraid to go to Neuralink with any questions that they have, any concerns, anything that they’re looking to do with this.
因此,我会告诉他们,不要害怕去 Neuralink 提出任何问题、任何疑虑、任何他们想要做的事情。
And any help that Neuralink is capable of providing, I know they will.
我知道 Neuralink 能够提供的任何帮助他们都会提供。
And I don’t know.
我不知道。
I don’t know.
我不知道。
Just work your ass off because it’s really important that we try to give our all to this.
努力工作吧,因为我们要全力以赴,这一点非常重要。
So have fun and work hard.
所以,玩得开心,努力工作。
Yeah.
是的。
8:11:21 Yeah.
是的。
There we go.
我们开始吧。
Maybe that’s what I’ll just start saying to people.
也许这就是我要开始对人们说的话。
Have fun, work hard.
玩得开心,努力工作。
Now you’re a real pro athlete.
现在你是一名真正的职业运动员了。
8:11:26 Just keep it short.
只要保持简短即可。
Maybe it’s good to talk about what you’ve been able to do now that you have a Neurolink implant, the freedom you gain from this way of interacting with the outside world.
也许最好谈谈您现在拥有 Neurolink 植入物后能够做的事情,以及您从这种与外界互动的方式中获得的自由。
You play video games all night and you do that by yourself, and that’s the freedom.
你整夜玩电子游戏,而且你自己玩,这就是自由。
Can you speak to that freedom that you gain?
您能谈谈您获得的自由吗?
Yeah.
是的。
8:11:53 It’s what all…
这就是一切……
I don’t know, people in my position want.
我不知道,处于我地位的人想要。
They just want more independence.
他们只是想要更多的独立性。
The more load that I can take away from people around me, the better.
我能从周围人身上分担的负担越多越好。
If I’m able to interact with the world without using my family, without going through any of my friends, needing them to help me with things, the better.
如果我能够在不借助家人、不通过任何朋友、不需要他们帮助我做事的情况下与世界互动,那就更好了。
If I’m able to sit up on my computer all night and not need someone to sit me up, say, on my iPad, in a position where I can use it, and then have to have them wait up for me all night until I’m ready to be done using it, it takes a load off of all of us and it’s really all I can ask for.
如果我能够整晚坐在电脑前,而不需要有人帮我坐起来,比如说,在我的 iPad 上,在我可以使用它的位置,然后让他们整晚等我,直到我准备好使用它,这会减轻我们所有人的负担,这确实是我所能要求的。
It’s something that I could never thank Neuralink enough for, and I know my family feels the same way.
我对 Neuralink 感激不尽,我知道我的家人也有同样的感受。
Just being able to have the freedom to do things on my own at any hour of the day or night, it means the world to me and…
只要能够在白天或晚上的任何时间自由地做自己的事情,这对我来说就意味着整个世界......
I don’t know.
我不知道。
When you’re up at 2:00 AM playing Webgrid by yourself, I just imagine it’s darkness and there’s just a light glowing and you’re just focused.
当你凌晨 2:00 起床独自玩 Webgrid 时,我只是想象周围一片黑暗,只有一盏灯在发光,而你只是专注。
8:13:02 What’s going through your mind?
你脑子里在想什么?
Or you were in a state of flow where it’s like the mind is empty like those Zen masters.
或者你像那些禅宗大师一样处于一种流动的状态,就像头脑是空的。
Yeah.
是的。
8:13:22 Generally, it is me playing music of some sort.
一般来说,是我在演奏某种音乐。
I have a massive playlist, and so I’m just rocking out to music.
我有一个庞大的播放列表,所以我只是随着音乐摇摆。
And then it’s also just a race against time, because I’m constantly looking at how much battery percentage I have left on my implant, like, “All right.
这也是一场与时间的赛跑,因为我不断地查看我的植入物上还剩下多少电池百分比,就像,“好吧。
I have 30%, which equates to X amount of time, which means I have to break this record in the next hour and a half or else it’s not happening tonight.” And so it’s a little stressful when that happens.
我有 30%,相当于 X 时间,这意味着我必须在接下来的一个半小时内打破这个记录,否则今晚就不会发生。”所以当这种情况发生时会有点压力。
When it’s above 50%, I’m like, “Okay, I got time.” It starts getting down to 30, and then 20 it’s like, “All right, 10%, a little popup is going to pop up right here, and it’s going to really screw my Webgrid flow.
当它超过 50% 时,我会说,“好吧,我还有时间。”它开始下降到 30,然后是 20,就像,“好吧,10%,这里会弹出一个小弹出窗口,它会真正破坏我的 Webgrid 流程。
It’s going to tell me that…
它会告诉我……
The low battery popup comes up and I’m like, “It’s really going to screw me over.
电池电量不足的弹出窗口出现,我想,“这真的要把我搞砸了。
So if I’m going to break this record, I have to do it in the next 30 seconds,” or else that popup is going to get in the way, cover my Webgrid.
因此,如果我要打破这个记录,我必须在接下来的 30 秒内完成,”否则该弹出窗口就会挡住我的网络网格。
8:14:26 And then after that, I go click on it, go back into Webgrid, and I’m like, “All right, that means I have 10 minutes left before this thing’s dead.” That’s what’s going on in my head, generally.
然后,我点击它,返回 Webgrid,然后我说,“好吧,这意味着我还有 10 分钟的时间,这个东西就会消失。”一般来说,这就是我脑子里发生的事情。
That and whatever song’s playing.
那首歌以及正在播放的任何歌曲。
And I want to break those records so bad.
我非常想打破这些记录。
It’s all I want when I’m playing Webgrid.
当我玩 Webgrid 时,这就是我想要的。
It has become less of like, “Oh, this is just a leisurely activity.
它不再像“哦,这只是一项休闲活动。
I just enjoy doing this because it just feels so nice and it puts me at ease.” It is, “No.
我只是喜欢这样做,因为它感觉很好,让我很放松。”是,“不。
Once I’m in Webgrid, you better break this record or you’re going to waste five hours of your life right now.” And I don’t know.
一旦我进入 Webgrid,你最好打破这个记录,否则你现在就会浪费你生命中的五个小时。”我不知道。
It’s just fun.
这很有趣。
It’s fun, man.
这很有趣,伙计。
Have you ever tried Webgrid with two targets and three targets?
您是否尝试过具有两个目标和三个目标的 Webgrid?
8:15:05 Can you get higher BPS with that?
这样你能获得更高的 BPS 吗?
Can you do that?
你能做到吗?
You mean different colored targets or you mean-
你的意思是不同颜色的目标或者你的意思是-
Oh, multiple targets.
哦,多个目标。
8:15:14 Does that change the thing?
这会改变事情吗?
Yeah.
是的。
8:15:16 So BPS is a log of number of targets times correct minus incorrect, divided by time.
因此,BPS 是正确目标次数减去错误目标次数除以时间的对数。
And so you can think of different clicks as basically double the number of active targets.
因此,您可以将不同的点击视为活动目标数量的两倍。
Got it.
明白了。
So basically higher BPS, the more options there are, the more difficult the task.
所以基本上 BPS 越高,选择越多,任务就越困难。
8:15:26 And there’s also Zen mode you’ve played in before, which is infinite-
还有你以前玩过的禅宗模式,是无限的——
Yeah.
是的。
8:15:33 Yeah.
是的。
It covers the whole screen with a grid and…
它用网格覆盖整个屏幕......
I don’t know-
我不知道-
And so you can go…
这样你就可以走了……
8:15:41 That’s insane.
这太疯狂了。
Yeah.
是的。
He doesn’t like it because it didn’t show BPS, so-
他不喜欢它,因为它没有显示 BPS,所以-
I had them put in a giant BPS in the background, so now it’s the opposite of Zen mode.
我让它们在后台放置了一个巨大的 BPS,所以现在它与 Zen 模式相反。
8:15:49 It’s super hard mode, just metal mode.
这是超级困难模式,只是金属模式。
If it’s just a giant number in the back [inaudible 08:16:01].
如果它只是后面的一个巨大数字 [听不清 08:16:01]。
We should renamed that.
我们应该重命名它。
8:16:01 Metal mode is a much better [inaudible 08:16:03].
金属模式要好得多 [听不清 08:16:03]。
So you also play Civilization VI.
所以你也玩文明VI。
I love Civ VI.
我喜欢《公民六》。
8:16:08 Yeah.
是的。
Usually go with Korea, you said?
你说通常去韩国?
I do.
我愿意。
8:16:11 Yeah.
是的。
So the great part about Korea is they focus on science tech victories, which was not planned.
因此,韩国最重要的一点是他们专注于科学技术的胜利,而这是没有计划的。
I’ve been playing Korea for years, and then all of the [inaudible 08:16:23] stuff happened, so it aligns.
我已经打韩国很多年了,然后所有的[听不清 08:16:23] 的事情都发生了,所以它是一致的。
But what I’ve noticed with tech victories is if you can just rush tech, rush science, then you can do anything.
但我在技术胜利中注意到的是,如果你能加快技术、加快科学,那么你就可以做任何事情。
At one point in the game, you’ll be so far ahead of everyone technologically that you’ll have musket men, infantrymen, planes sometimes, and people will still be fighting with bows and arrows.
在游戏的某一时刻,你在技术上远远领先于所有人,有时你会有火枪手、步兵、飞机,而人们仍然会用弓箭战斗。
And so if you want to win a domination victory, you just get to a certain point with the science, and then go and wipe out the rest of the world.
因此,如果你想赢得统治胜利,你只需在科学上达到一定程度,然后去消灭世界其他地方。
Or you can just take science all the way and win that way, and you’re going to be so far ahead of everyone because you’re producing so much science that it’s not even close.
或者你可以一直采用科学并以此方式获胜,你将遥遥领先于所有人,因为你产生了如此多的科学成果,甚至还没有接近。
I’ve accidentally won in different ways just by focusing on science.
仅仅通过专注于科学,我就意外地以不同的方式获胜。
Accidentally won by focusing on science-
专注于科学意外获胜——
Yeah.
是的。
8:17:20 I was playing only science, obviously.
显然,我只玩科学。
Just science all the way, just tech.
一直都是科学,只是技术。
And I was trying to get every tech in the tech tree and stuff, and then I accidentally won through a diplomatic victory, and I was so mad.
我试图获得科技树中的每一项科技之类的东西,然后我意外地通过外交胜利获胜,我非常生气。
I was so mad because it just ends the game one turn.
我很生气,因为游戏一回合就结束了。
It was like, “Oh, you won.
就像是,“哦,你赢了。
You’re so diplomatic.” I’m like, “I don’t want to do this.
你真是太有外交手腕了。”我想,“我不想这样做。
I should have declared war on more people or something.” It was terrible.
我应该向更多的人宣战或者其他什么。”太可怕了。
But you don’t need giant civilizations with tech, especially with Korea.
但你不需要拥有科技的巨型文明,尤其是韩国。
You can keep it pretty small.
你可以把它保持得很小。
So I generally just get to a certain military unit and put them all around my border to keep everyone out, and then I will just build up.
所以我通常只是到达某个军事单位并将它们放在我的边界周围以将所有人拒之门外,然后我就会建立起来。
So very isolationist.
所以非常孤立主义者。
Nice.
不错。
Yeah.
是的。
Just work on the science and the tech.
只是致力于科学和技术。
Yep, that’s it.
是的,就是这样。
You’re making it sound so fun.
你让它听起来很有趣。
It’s so much fun.
太有趣了。
And I also saw a Civilization VII trailer.
我还看到了《文明VII》的预告片。
Oh, man.
哦,伙计。
8:18:13 I’m so pumped.
我很兴奋。
And that’s probably coming out-
这可能会出来——
Come on Civ VII, hit me up.
来吧《文明VII》,来打我吧。
8:18:16 All alpha, beta tests, whatever.
所有 alpha、beta 测试,等等。
Wait, when is it coming out?
等等,什么时候出?
2025.
2025 年。
Yeah, yeah, next year.
是啊是啊,明年吧
8:18:22 Yeah.
是的。
What other stuff would you like to see improved about the Neuralink app and just the entire experience?
您还希望看到 Neuralink 应用程序以及整个体验的哪些方面得到改进?
I would like to, like I said, get back to the click on demand, the regular clicks.
正如我所说,我想回到按需点击、常规点击。
8:18:29 That would be great.
那太好了。
I would like to be able to connect to more devices.
我希望能够连接到更多设备。
Right now, it’s just the computer.
现在,只有电脑了。
I’d like to be able to use it on my phone or use it on different consoles, different platforms.
我希望能够在我的手机上使用它,或者在不同的游戏机、不同的平台上使用它。
I’d like to be able to control as much stuff as possible, honestly.
老实说,我希望能够控制尽可能多的事情。
An Optimus robot would be pretty cool.
擎天柱机器人会很酷。
That would be sick if I could control an Optimus robot.
如果我能控制擎天柱机器人那就太恶心了。
The Link app itself, it seems like we are getting pretty dialed in to what it might look like down the road.
Link 应用程序本身,我们似乎已经很熟悉它未来的样子了。
It seems like we’ve gotten through a lot of what I want from it, at least.
看来我们至少已经经历了很多我想要的事情。
The only other thing I would say is more control over all the parameters that I can tweak with my cursor and stuff.
我要说的唯一一件事是更好地控制我可以用光标和其他东西调整的所有参数。
There’s a lot of things that go into how the cursor moves in certain ways, and I have…
有很多事情涉及光标如何以某种方式移动,我已经......
I don’t know.
我不知道。
Three or four of those parameters, and there might-
其中三个或四个参数,可能-
Gain and friction and all that.
增益和摩擦等等。
Gain and friction, yeah.
增益和摩擦,是的。
8:19:43 And there’s maybe double the amount of those with just velocity and then with the actual [inaudible 08:19:51] cursor.
仅使用速度和实际 [听不清 08:19:51] 光标的数量可能是其数量的两倍。
So I would like all of it.
所以我想要这一切。
I want as much control over my environment as possible, especially-
我希望尽可能多地控制我的环境,尤其是-
So you want advanced mode.
所以你需要高级模式。
8:19:58 There’s usually this basic mode, and you’re one of those folks, the power-user, advanced-
通常有这种基本模式,而你就是这些人中的一员,高级用户,高级-
Yeah.
是的。
8:20:06 Yeah.
是的。
Got it.
明白了。
That’s what I want.
这就是我想要的。
8:20:07 I want as much control over this as possible.
我希望对此有尽可能多的控制。
So, yeah, that’s really all I can ask for.
所以,是的,这就是我所能要求的。
Just give me everything.
只要给我一切。
Has speech been useful?
说话有用吗?
8:20:18 Just being able to talk also in addition to everything else?
除了其他一切之外,还能说话吗?
Yeah, you mean while I’m using it?
是的,你是说当我使用它的时候?
While you’re using it?
当你使用它的时候?
8:20:25 Speech-to-text?
语音转文字?
Oh, yeah.
哦,是的。
Or do you type…
或者你输入...
8:20:28 Because there’s also a keyboard-
因为还有键盘——
Yeah, yeah, yeah.
是啊,是啊,是啊。
8:20:30 So there’s a virtual keyboard.
所以就有了虚拟键盘。
That’s another thing I would like to work more on is finding some way to type or text in a different way.
我想要做更多工作的另一件事是找到某种方式以不同的方式打字或发短信。
Right now, it is a dictation basically and a virtual keyboard that I can use with the cursor, but we’ve played around with finger spelling, sign language finger spelling, and that seems really promising.
现在,它基本上是一个听写和一个可以与光标一起使用的虚拟键盘,但我们已经尝试过手指拼写、手语手指拼写,这看起来非常有前途。
So I have this thought in my head that it’s going to be a very similar learning curve that I had with the cursor where I went from attempted movement to imagine movement at one point.
所以我脑子里有这样的想法,这将是一个与我对光标的非常相似的学习曲线,我从尝试移动到想象在某一点上的移动。
I have a feeling, this is just my intuition, that at some point, I’m going to be doing finger spelling and I won’t need to actually attempt to finger spell anymore, that I’ll just be able to think the letter that I want and it’ll pop up.
我有一种感觉,这只是我的直觉,在某个时候,我将进行手指拼写,我不再需要实际尝试手指拼写,我只需想到我想要的字母,它就会弹出。
That would be epic.
那将是史诗般的。
8:21:24 That’s challenging.
这很有挑战性。
That’s hard.
这很难。
That’s a lot of work for you to take that leap, but that would be awesome.
要实现这一飞跃,你需要做很多工作,但这会很棒。
And then going from letters to words is another step.
然后从字母到单词是另一个步骤。
8:21:30 Right now, it’s finger spelling of just the sign language alphabet, but if it’s able to pick that up, then it should be able to pick up the whole sign language language, and so then if I could do something along those lines, or just the sign language spelled word, if I can spell it at a reasonable speed and it can pick that up, then I would just be able to think that through and it would do the same thing.
现在,它只是手语字母表的手指拼写,但如果它能够识别出来,那么它应该能够识别整个手语语言,所以如果我可以沿着这些思路做一些事情,或者只是手语拼写的单词,如果我能以合理的速度拼写它并且它可以识别它,那么我就能够思考,并且它会做同样的事情。
After what I saw with the cursor control, I don’t see why it wouldn’t work, but we’d have to play around with it more.
在我看到光标控件之后,我不明白为什么它不起作用,但我们必须更多地尝试它。
What was the process in terms of training yourself to go from attempted movement to imagined movement?
训练自己从尝试运动到想象运动的过程是怎样的?
8:22:10 How long did that take?
那花了多长时间?
So how long would this process take?
那么这个过程需要多长时间呢?
Well, it was a couple weeks before it just happened upon me.
好吧,几周后它才发生在我身上。
8:22:19 But now that I know that that was possible, I think I could make it happen with other things.
但现在我知道这是可能的,我想我可以通过其他事情来实现它。
I think it would be much, much simpler.
我认为这会简单得多。
Would you get an upgraded implant device?
您会获得升级版植入设备吗?
Sure, absolutely.
当然,绝对。
8:22:34 Whenever they’ll let me.
每当他们允许我的时候。
So you don’t have any concerns for you with the surgery experience?
那么您对手术经历没有任何顾虑吗?
8:22:39 All of it was no regrets?
这一切都没有遗憾吗?
No.
不。
So everything’s been good so far?
那么到目前为止一切都很好吗?
Yep.
是的。
You just keep getting upgrades.
您只需不断升级即可。
Yeah.
是的。
8:22:50 I mean, why not?
我的意思是,为什么不呢?
I’ve seen how much it’s impacted my life already, and I know that everything from here on out, it’s just going to get better and better.
我已经看到它对我的生活产生了多大的影响,而且我知道从现在开始,一切都会变得越来越好。
So I would love to get the upgrade.
所以我很想升级。
What future capabilities are you excited about?
您对哪些未来功能感到兴奋?
8:23:02 So beyond this telepathy, is vision interesting?
那么除了心灵感应之外,视觉还有趣吗?
So for folks, for example, who are blind, so Neuralink enabling people to see, or for speech.
例如,对于盲人来说,Neuralink 可以帮助人们看到东西或讲话。
Yeah, there’s a lot that’s very, very cool about this.
是的,这有很多非常非常酷的地方。
8:23:19 I mean, we’re talking about the brain, so this is just motor cortex stuff.
我的意思是,我们谈论的是大脑,所以这只是运动皮层的东西。
There’s so much more that can be done.
还有很多事情可以做。
The vision one is fascinating to me.
这个愿景对我来说很着迷。
I think that is going to be very, very cool.
我认为这将非常非常酷。
To give someone the ability to see for the first time in their life would just be…
让某人有生以来第一次看到东西的能力只是……
I mean, it might be more amazing than even helping someone like me.
我的意思是,这可能比帮助像我这样的人更令人惊奇。
That just sounds incredible.
这听起来令人难以置信。
The speech thing is really interesting.
演讲的事情真的很有趣。
Being able to have some real-time translation and cut away that language barrier would be really cool.
能够进行实时翻译并消除语言障碍真是太酷了。
Any actual impairments that it could solve with speech would be very, very cool.
它可以通过语音解决任何实际障碍,这将是非常非常酷的。
8:24:00 And then also, there are a lot of different disabilities that all originate in the brain, and you would be able to hopefully be able to solve a lot of those.
而且,有很多不同的残疾都起源于大脑,你有望能够解决其中的很多问题。
I know there’s already stuff to help people with seizures that can be implanted in the brain.
我知道已经有一些东西可以植入大脑来帮助癫痫患者。
I imagine the same thing.
我想象同样的事情。
And so you could do something like that.
所以你可以做类似的事情。
I know that even someone like Joe Rogan has talked about the possibilities with being able to stimulate the brain in different ways.
我知道,甚至像乔·罗根这样的人也谈到了以不同方式刺激大脑的可能性。
I’m not sure how ethical a lot of that would be.
我不确定其中有多少是道德的。
That’s beyond me, honestly.
老实说,这超出了我的范围。
But I know that there is a lot that can be done when we’re talking about the brain and being able to go in and physically make changes to help people or to improve their lives.
但我知道,当我们谈论大脑并能够进入并在身体上做出改变以帮助人们或改善他们的生活时,我们可以做很多事情。
So I’m really looking forward to everything that comes from this.
所以我真的很期待由此带来的一切。
And I don’t think it’s all that far off.
我认为这一切并不遥远。
I think a lot of this can be implemented within my lifetime, assuming that I live a long life.
我认为,假设我的寿命很长,其中很多都可以在我的有生之年实现。
What you were referring to is things like people suffering from depression or things of that nature, potentially getting help.
你指的是患有抑郁症或类似性质的人可能会获得帮助。
Yeah, flip a switch like that, make someone happy.
是的,像这样拨动开关,让某人开心。
8:25:14 I think Joe has talked about it more in terms of you want to experience what a drug trip feels like.
我认为乔更多地谈到了你想要体验毒品之旅的感觉。
You want to experience what it’d be like to be on mushrooms or something like that, DMT.
你想体验一下吃蘑菇或类似的东西,DMT 的感觉。
You can just flip that switch in the brain.
你只需打开大脑中的开关即可。
My buddy, Bain, has talked about being able to wipe parts of your memory and re-experience things for the first time, like your favorite movie or your favorite book, just wipe that out real quick, and then re-fall in love with Harry Potter or something.
我的朋友贝恩曾谈到能够抹掉你的部分记忆并重新体验第一次的事物,比如你最喜欢的电影或你最喜欢的书,很快就把它抹掉,然后重新爱上哈利·波特之类的东西。
I told him, I was like, “I don’t know how I feel about people being able to just wipe parts of your memory.
我告诉他,我当时想,“我不知道我对人们能够抹去你的部分记忆有什么感觉。
That seems a little sketchy to me.” He’s like, “They’re already doing it.”
这对我来说似乎有点粗略。”他说:“他们已经在这么做了。”
Sounds legit.
听起来合法。
8:25:59 I would love memory replay.
我喜欢记忆重播。
Just actually high resolution, replay of old memories.
实际上只是高分辨率,旧记忆的重播。
Yeah.
是的。
8:26:07 I saw an episode of Black Mirror about that once, so I don’t think I want it.
我曾经看过《黑镜》中关于此事的一集,所以我认为我不想要它。
Yeah, so Black Mirror always considers the worst case, which is important.
是的,所以《黑镜》总是考虑最坏的情况,这一点很重要。
8:26:10 I think people don’t consider the best case or the average case enough.
我认为人们没有充分考虑最好的情况或平均的情况。
I don’t know what it is about us humans.
我不知道我们人类是什么。
We want to think about the worst possible thing.
我们想考虑最坏的情况。
We love drama.
我们喜欢戏剧。
It’s like how is this new technology going to kill everybody?
就像这项新技术如何杀死所有人一样?
We just love that.
我们就是喜欢这样。
Again like, “Yes, let’s watch.”
再次就像,“是的,让我们看看。”
Hopefully people don’t think about that too much with me.
希望人们不要和我一起想太多。
8:26:32 It’ll ruin a lot of my plans.
它会毁掉我的很多计划。
Yeah, I assume you’re going to have to take over the world.
是的,我想你将不得不接管世界。
8:26:37 I mean, I love your Twitter.
我的意思是,我喜欢你的推特。
You tweeted, “I’d like to make jokes about hearing voices in my head since getting the Neuralink, but I feel like people would take it the wrong way.
你在推特上写道:“自从获得 Neuralink 以来,我想开个玩笑,说我脑子里听到了声音,但我觉得人们会误解它。
Plus the voices in my head told me not to.”
而且我脑子里的声音告诉我不要这样做。”
Yeah.
是的。
Yeah.
是的。
Yeah.
是的。
Please never stop.
请永远不要停止。
8:26:53 So you were talking about Optimus.
所以你在谈论擎天柱。
Is that something you would love to be able to do to control the robotic arm or the entirety of Optimus?
您是否希望能够控制机械臂或整个擎天柱?
Oh, yeah, for sure.
哦,是的,当然。
8:27:05 For sure.
当然。
Absolutely.
绝对的。
You think there’s something fundamentally different about just being able to physically interact with the world?
你认为仅仅能够与世界进行身体互动有什么本质上的不同吗?
Yeah.
是的。
8:27:12 Oh, 100%.
哦,100%。
I know another thing with being able to give people the ability to feel sensation and stuff too, by going in with the brain and having a Neuralink maybe do that, that could be something that could be transferred through the Optimus as well.
我知道另一件事是能够让人们有能力感受感觉和其他东西,通过进入大脑并让 Neuralink 可以做到这一点,这也可以通过擎天柱转移。
There’s all sorts of really cool interplay between that.
它们之间存在着各种非常酷的相互作用。
And then also, like you said, just physically interacting.
然后,就像你说的,只是身体上的互动。
I mean, 99% of the things that I can’t do myself, obviously, I need a caretaker for, someone to physically do things for me.
我的意思是,99% 的事情我自己无法完成,显然,我需要一个看护者,有人亲自为我做事。
If an Optimus robot could do that, I could live an incredibly independent life and not be such a burden on those around me, and it would change the way people like me live, at least until whatever this is gets cured.
如果擎天柱机器人能够做到这一点,我就可以过上令人难以置信的独立生活,而不会成为周围人的负担,这将改变像我这样的人的生活方式,至少在这种情况得到治愈之前是这样。
8:28:12 But being able to interact with the world physically, that would just be amazing.
但能够与世界进行物理互动,那就太棒了。
And not just for having it be a caretaker or something, but something like I talked about.
不仅仅是让它成为看门人之类的,而是像我所说的那样。
Just being able to read a book.
只要能看书就可以了。
Imagine an Optimus robot just being able to hold a book open in front of me.
想象一下,一个擎天柱机器人能够在我面前打开一本书。
I get that smell again.
我又闻到了那种味道。
I might not be able to feel it at that point, or maybe I could, again, with the sensation and stuff.
那时我可能无法感觉到它,或者也许我可以再次感受到这种感觉和东西。
But there’s something different about reading a physical book than staring at a screen or listening to an audiobook.
但阅读实体书与盯着屏幕或听有声读物有一些不同。
I actually don’t like audiobooks.
其实我不喜欢有声读物。
I’ve listened to a ton of them at this point, but I don’t really like them.
我现在已经听了很多,但我不太喜欢它们。
I would much rather read a physical copy.
我更愿意阅读实体版。
So one of the things you would love to be able to experience is opening the book, bringing it up to you, and to feel the touch of the paper.
因此,您希望能够体验的事情之一就是打开这本书,将其带到您面前,并感受纸张的触感。
Yeah.
是的。
8:29:01 Oh, man.
哦,伙计。
The touch, the smell.
触觉、气味。
I mean, it’s just something about the words on the page.
我的意思是,这只是关于页面上的文字。
And they’ve replicated that page color on the Kindle and stuff.
他们在 Kindle 等设备上复制了页面颜色。
Yeah, it’s just not the same.
是的,只是不一样。
Yeah.
是的。
So just something as simple as that.
就这么简单。
So one of the things you miss is touch?
那么你想念的事情之一就是触摸吗?
I do.
我愿意。
8:29:20 Yeah.
是的。
A lot of things that I interact with in the world, like clothes or literally any physical thing that I interact within the world, a lot of times what people around me will do is they’ll just come rub it on my face.
我在世界上互动的很多东西,比如衣服或者我在世界上互动的任何物理事物,很多时候我周围的人会做的就是把它擦在我的脸上。
They’ll lay something on me so I can feel the weight.
他们会在我身上放一些东西,这样我就能感觉到重量。
They will rub a shirt on me so I can feel fabric.
他们会在我身上擦一件衬衫,这样我就能感觉到布料的感觉。
There’s something very profound about touch, and it’s something that I miss a lot and something I would love to do again.
触摸有一些非常深刻的东西,这是我非常怀念的东西,也是我很想再次做的事情。
We’ll see.
我们会看到的。
What would be the first thing you do with a hand that can touch?
如果你有一只可以触摸的手,你会做的第一件事是什么?
8:29:56 Give your mom a hug after that, right?
然后给你妈妈一个拥抱吧?
Yeah.
是的。
8:30:02 I know.
我知道。
It’s one thing that I’ve asked God for basically every day since my accident was just being able to one day move, even if it was only my hand, so that way, I could squeeze my mom’s hand or something just to show her how much I care and how much I love her and everything.
这是我基本上每天都向上帝祈求的一件事,因为我的事故只是有一天能够移动,即使只是我的手,这样,我就可以挤压我妈妈的手或其他什么东西,只是为了向她展示我有多么在乎,我有多么爱她和一切。
Something along those lines.
沿着这些思路。
Being able to just interact with the people around me.
能够与周围的人互动。
Handshake, give someone a hug.
握手,给某人一个拥抱。
I don’t know.
我不知道。
Anything like that.
任何类似的事情。
Being able to help me eat.
能够帮我吃饭。
I’d probably get really fat, which would be a terrible, terrible thing.
我可能会变得非常胖,这将是一件非常非常糟糕的事情。
Also, beat Bliss in chess on a physical board.
此外,还可以在实体棋盘上的国际象棋比赛中击败布利斯。
Yeah.
是的。
8:30:47 Yeah.
是的。
I mean, there were just so many upsides.
我的意思是,有很多好处。
And any way to find some way to feel like I’m bringing Bliss down to my level because he’s just such an amazing guy, and everything about him is just so above and beyond, that anything I can do to take him down a notch, I’m more than happy-
无论如何,找到某种方式让我感觉自己正在将布利斯降低到我的水平,因为他真是一个了不起的人,他的一切都是那么的超凡脱俗,无论我能做些什么来把他拉低一个档次,我都非常高兴——
Yeah.
是的。
8:31:10 Yeah, humble him a bit.
是的,让他谦虚一点。
He needs it.
他需要它。
Yeah.
是的。
Okay.
好的。
8:31:13 As he’s sitting next to me.
当他坐在我旁边时。
Did you ever make sense of why God puts good people through such hardship?
你是否明白神为什么让好人经历这样的苦难呢?
Oh, man.
哦,伙计。
8:31:23 I think it’s all about understanding how much we need God.
我认为这一切都在于了解我们有多么需要上帝。
And I don’t think that there’s any light without the dark.
我认为没有黑暗就没有光明。
I think that if all of us were happy all the time, there would be no reason to turn to God ever.
我认为,如果我们所有人一直都快乐,就没有理由转向上帝。
I feel like there would be no concept of good or bad, and I think that as much of the darkness and the evil that’s in the world, it makes us all appreciate the good and the things we have so much more.
我觉得不会有好坏的概念,我认为世界上有那么多的黑暗和邪恶,它让我们所有人更加珍惜我们所拥有的美好和事物。
And I think when I had my accident, one of the first things I said to one of my best friends was…
我想当我发生事故时,我对我最好的朋友说的第一句话是……
And this was within the first month or two after my accident, I said, “Everything about this accident has just made me understand and believe that God is real and that there really is a God, basically.
这是在我发生事故后的一两个月内,我说:“关于这次事故的一切让我理解并相信上帝是真实的,基本上真的有一个上帝。
And that my interactions with him have all been real and worthwhile.”
我和他的互动都是真实且有价值的。”
8:32:32 And he said, if anything, seeing me go through this accident, he believes that there isn’t a God.
他说,如果有的话,看到我经历这次事故,他相信没有上帝。
And it’s a very different reaction, but I believe that it is a way for God to test us, to build our character, to send us through trials and tribulations, to make sure that we understand how precious He is and the things that He’s given us and the time that He’s given us, and then to hopefully grow from all of that.
这是一种非常不同的反应,但我相信这是上帝考验我们、塑造我们品格、送我们经历考验和磨难的一种方式,以确保我们理解他是多么宝贵,以及他给我们的东西和他给我们的时间,然后希望从这一切中成长。
I think that’s a huge part of being here, is to not just have an easy life and do everything that’s easy, but to step out of our comfort zones and really challenge ourselves because I think that’s how we grow.
我认为这是在这里的一个重要部分,不仅是过轻松的生活,做一切容易的事情,而且要走出我们的舒适区,真正挑战自己,因为我认为这就是我们成长的方式。
What gives you hope about this whole thing we have going on human civilization?
是什么让你对人类文明所发生的一切充满希望?
Oh, man.
哦,伙计。
8:33:27 I think people are my biggest inspiration.
我认为人是我最大的灵感。
Even just being at Neuralink for a few months, looking people in the eyes and hearing their motivations for why they’re doing this, it’s so inspiring.
即使只是在 Neuralink 呆了几个月,看着人们的眼睛,听听他们这样做的动机,这都非常鼓舞人心。
And I know that they could be other places, at cushier jobs, working somewhere else, doing X, Y, or Z, that doesn’t really mean that much.
我知道他们可能在其他地方,从事更轻松的工作,在其他地方工作,做 X、Y 或 Z,这并没有多大意义。
But instead, they’re here and they want to better humanity, and they want to better just the people around them.
但相反,他们来到这里,他们想要改善人性,他们想要改善周围的人。
The people that they’ve interacted with in their life, they want to make better lives for their own family members who might have disabilities, or they look at someone like me and they say, “I can do something about that.
他们在生活中接触过的人,他们希望为自己可能患有残疾的家庭成员过上更好的生活,或者他们看着像我这样的人,他们说:“我可以为此做点什么。
So I’m going to.” And it’s always been what I’ve connected with most in the world are people.
所以我就去。”我在世界上与人联系最紧密的一直是人。
8:34:22 I’ve always been a people person and I love learning about people, and I love learning how people developed and where they came from, and to see how much people are willing to do for someone like me when they don’t have to, and they’re going out of their way to make my life better.
我一直是一个善于交际的人,我喜欢了解人们,我喜欢了解人们如何发展以及他们来自哪里,并了解人们在不必要的时候愿意为像我这样的人做多少事情,并且他们不遗余力地让我的生活变得更好。
It gives me a lot of hope for just humanity in general, how much we care and how much we’re capable of when we all get together and try to make a difference.
这让我对整个人类抱有很大的希望,看到当我们齐心协力并努力做出改变时,我们有多么关心,我们有多大能力。
And I know there’s a lot of bad out there in the world, but there always has been and there always will be.
我知道世界上有很多不好的事情,但过去总是存在,将来也永远存在。
And I think that that is…
我认为那是……
It shows human resiliency and it shows what we’re able to endure and how much we just want to be there and help each other, and how much satisfaction we get from that, because I think that’s one of the reasons that we’re here is just to help each other, and…
它显示了人类的韧性,显示了我们能够忍受的事情,以及我们多么想在那里互相帮助,以及我们从中获得了多少满足感,因为我认为这就是我们在这里只是为了互相帮助的原因之一,而且……
I don’t know.
我不知道。
That always gives me hope, is just realizing that there are people out there who still care and who want to help.
这总是给我带来希望,只是意识到有人仍然关心并想要提供帮助。
And thank you for being one such human being and continuing to be a great human being through everything you’ve been through and being an inspiration to many people, to myself, for many reasons, including your epic, unbelievably great performance on Webgrid.
感谢你成为这样的人,并通过你所经历的一切继续成为一个伟大的人,并出于多种原因激励许多人和我自己,包括你在 Webgrid 上史诗般的、令人难以置信的出色表现。
8:35:31 I’ll be training all night tonight to try to catch up.
今晚我将整夜训练,试图赶上。
Hey, man.
嘿,伙计。
8:35:52 You can do it.
你可以做到的。
You can do it.
你可以做到的。
And I believe in you that once you come back…
我相信你,一旦你回来......
So sorry to interrupt with the Austin trip, once you come back, eventually beat Bliss.
很抱歉打断奥斯汀之旅,一旦你回来,最终会击败布利斯。
Yeah, yeah, for sure.
是的,是的,当然。
8:36:00 Absolutely.
绝对的。
I’m rooting for you, though.
不过,我支持你。
8:36:02 The whole world is rooting for you.
全世界都在支持你。
Thank you.
谢谢你。
Thank you for everything you’ve done, man.
谢谢你所做的一切,伙计。
Thanks.
谢谢。
8:36:07 Thanks, man.
谢谢,伙计。
Thanks for listening to this conversation with Nolan Arbaugh, and before that, with Elon Musk, DJ Seo, Matthew McDougall, and Bliss Chapman.
感谢您收听诺兰·阿博 (Nolan Arbaugh) 的对话,以及在此之前收听埃隆·马斯克 (Elon Musk)、DJ Seo、马修·麦克杜格尔 (Matthew McDougall) 和布利斯·查普曼 (Bliss Chapman) 的对话。
8:36:09 To support this podcast, please check out our sponsors in the description.
为了支持这个播客,请在说明中查看我们的赞助商。
And now, let me leave you with some words from Aldous Huxley in The Doors of Perception.
现在,让我向您介绍奥尔德斯·赫胥黎在《知觉之门》中的一些话。
“We live together.
“我们住在一起。
We act on and react to one another.
我们互相行动、互相反应。
But always, and in all circumstances, we are by ourselves.
但在任何情况下,我们总是独自一人。
The martyrs go hand in hand into the arena.
烈士们手挽着手走进竞技场。
They are crucified alone.
他们独自被钉在十字架上。
Embrace the lovers desperately tried to fuse their insulated ecstasies into a single self-transcendence in vain.
拥抱这对恋人拼命地试图将他们孤立的狂喜融合成单一的自我超越,但徒劳无功。
But it’s very nature, every embodied spirit is doomed to suffer and enjoy its solitude, sensations, feelings, insights, fancies, all these are private, and except through symbols and a secondhand incommunicable.
但这是很自然的,每一个具体的精神都注定要受苦并享受它的孤独,感觉、感情、洞察力、幻想,所有这些都是私人的,除非通过符号和二手的不可交流的东西。
We can pool information about experiences, but never the experiences themselves.
我们可以汇集有关体验的信息,但不能汇集体验本身。
From family to nation, every human group is a society of island universes.” Thank you for listening and hope to see you next time.
从家庭到国家,每个人类群体都是一个岛屿宇宙社会。”感谢您的聆听,并希望下次再见。
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